Works matching IS 00219738 AND DT 2012 AND VI 122 AND IP 6

Results: 46

TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2195, doi. 10.1172/JCI45414

By:

Liu, Tong;
Berta, Temugin;
Xu, Zhen-Zhong;
Park, Chul-Kyu;
Zhang, Ling;
Lü, Ning;
Liu, Qin;
Liu, Yang;
Gao, Yong-Jing;
Liu, Yen-Chin;
Ma, Qiufu;
Dong, Xinzhong;
Ji, Ru-Rong

Publication type:

Article

CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2257, doi. 10.1172/JCI45851

By:

Chung, Elaine Y.;
Psathas, James N.;
Yu, Duonan;
Li, Yimei;
Weiss, Mitchell J.;
Thomas-Tikhonenko, Andrei

Publication type:

Article

Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2208, doi. 10.1172/JCI45850

By:

Mahdi, Layla K.;
Wang, Hui;
Van der Hoek, Mark B.;
Paton, James C.;
Ogunniyi, Abiodun D.

Publication type:

Article

Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2104, doi. 10.1172/JCI61228

By:

Jasuja, Reema;
Passam, Freda H.;
Kennedy, Daniel R.;
Kim, Sarah H.;
Hessem, Lotte van;
Lin, Lin;
Bowley, Sheryl R.;
Joshi, Sucharit S.;
Dilks, James R.;
Furie, Bruce;
Furie, Barbara C.;
Flaumenhaft, Robert

Publication type:

Article

STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2267, doi. 10.1172/JCI59953

By:

Dramane, Gado;
Abdoul-Azize, Souleymane;
Hichami, Aziz;
Vögtle, Timo;
Akpona, Simon;
Chouabe, Christophe;
Sadou, Hassimi;
Nieswandt, Bernhard;
Besnard, Philippe;
Khan, Naim Akhtar

Publication type:

Article

Malonyl-CoA: the regulator of fatty acid synthesis and oxidation.

Published in:

2012

By:

Foster DW;
Foster, Daniel W

Publication type:

journal article

The molecular pathogenesis of head and neck squamous cell carcinoma.

Published in:

2012

By:

Rothenberg SM;
Ellisen LW;
Rothenberg, S Michael;
Ellisen, Leif W

Publication type:

journal article

A conversation with Lloyd Hollingsworth Smith Jr.

Published in:

2012

By:

Smith LH Jr;
Smith, Lloyd Hollingsworth Jr

Publication type:

Historical Material

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice.

Published in:

2012

By:

Pantelyushin S;
Haak S;
Ingold B;
Kulig P;
Heppner FL;
Navarini AA;
Becher B;
Pantelyushin, Stanislav;
Haak, Stefan;
Ingold, Barbara;
Kulig, Paulina;
Heppner, Frank L;
Navarini, Alexander A;
Becher, Burkhard

Publication type:

journal article

MicroRNA-181b regulates NF-κB-mediated vascular inflammation.

Published in:

2012

By:

Sun X;
Icli B;
Wara AK;
Belkin N;
He S;
Kobzik L;
Hunninghake GM;
Vera MP;
Blackwell TS;
Baron RM;
Feinberg MW;
MICU Registry;
Sun, Xinghui;
Icli, Basak;
Wara, Akm Khyrul;
Belkin, Nathan;
He, Shaolin;
Kobzik, Lester;
Hunninghake, Gary M;
Vera, Miguel Pinilla

Publication type:

journal article

Genetic modifiers of hypertension in soluble guanylate cyclase α1-deficient mice.

Published in:

2012

By:

Buys ES;
Raher MJ;
Kirby A;
Shahid M;
Mohd S;
Baron DM;
Hayton SR;
Tainsh LT;
Sips PY;
Rauwerdink KM;
Yan Q;
Tainsh RE;
Shakartzi HR;
Stevens C;
Decaluwé K;
Rodrigues-Machado Mda G;
Malhotra R;
Van de Voorde J;
Wang T;
Brouckaert P

Publication type:

journal article

Corrigendum.

Published in:: 2012
Publication type:: Correction Notice

Erratum.

Published in:: 2012
Publication type:: Correction Notice

Genetic modifiers of hypertension in soluble guanylate cyclase α1-deficient mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2316, doi. 10.1172/JCI60119

By:

Buys, Emmanuel S.;
Raher, Michael J.;
Kirby, Andrew;
Mohd, Shahid;
Baron, David M.;
Hayton, Sarah R.;
Tainsh, Laurel T.;
Sips, Patrick Y.;
Rauwerdink, Kristen M.;
Yan, Qingshang;
Tainsh, Robert E. T.;
Shakartzi, Hannah R.;
Stevens, Christine;
Decaluwé, Kelly;
Rodrigues-Machado, Maria da Gloria;
Malhotra, Rajeev;
Van de Voorde, Johan;
Wang, Tong;
Brouckaert, Peter;
Daly, Mark J.

Publication type:

Article

Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2306, doi. 10.1172/JCI61319

By:

Distler, Margaret G.;
Plant, Leigh D.;
Sokoloff, Greta;
Hawk, Andrew J.;
Aneas, Ivy;
Wuenschell, Gerald E.;
Termini, John;
Meredith, Stephen C.;
Nobrega, Marcelo A.;
Palmer, Abraham A.

Publication type:

Article

Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2301, doi. 10.1172/JCI61822

By:

Ojo, Kayode K.;
Pfander, Claudia;
Mueller, Natascha R.;
Burstroem, Charlotte;
Larson, Eric T.;
Bryan, Cassie M.;
Fox, Anna M. W.;
Reid, Molly C.;
Johnson, Steven M.;
Murphy, Ryan C.;
Kennedy, Mark;
Mann, Henning;
Leibly, David J.;
Hewitt, Stephen N.;
Verlinde, Christophe L. M. J.;
Kappe, Stefan;
Merritt, Ethan A.;
Maly, Dustin J.;
Billker, Oliver;
Van Voorhis, Wesley C.

Publication type:

Article

Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2289, doi. 10.1172/JCI57817

By:

Tan, Kai Soo;
Lee, Kok Onn;
Low, Kee Chung;
Gamage, Akshamal Mihiranga;
Liu, Yichun;
Tan, Gek-Yen Gladys;
Koh, Hui Qi Vanessa;
Alonso, Sylvie;
Gan, Yunn-Hwen

Publication type:

Article

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2283, doi. 10.1172/JCI61745

By:

Begus-Nahrmann, Yvonne;
Hartmann, Daniel;
Kraus, Johann;
Eshraghi, Parisa;
Scheffold, Annika;
Grieb, Melanie;
Rasche, Volker;
Schirmacher, Peter;
Lee, Han-Wong;
Kestler, Hans A.;
Lechel, André;
Rudolph, K. Lenhard

Publication type:

Article

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2176, doi. 10.1172/JCI41636

By:

Benhamed, Fadila;
Denechaud, Pierre-Damien;
Lemoine, Maud;
Robichon, Céline;
Moldes, Marthe;
Bertrand-Michel, Justine;
Ratziu, Vlad;
Serfaty, Lawrence;
Housset, Chantal;
Capeau, Jacqueline;
Girard, Jean;
Guillou, Hervé;
Postic, Catherine

Publication type:

Article

p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2153, doi. 10.1172/JCI62644

By:

Wang, Yingli;
Zhou, Xueyan;
Oberoi, Kurun;
Phelps, Robert;
Couwenhoven, Ross;
Sun, Miao;
Rezza, Amélie;
Holmes, Greg;
Percival, Christopher J.;
Friedenthal, Jenna;
Krejci, Pavel;
Richtsmeier, Joan T.;
Huso, David L.;
Rendl, Michael

Publication type:

Article

Rorγt<sup>+</sup> innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2252, doi. 10.1172/JCI61862

By:

Pantelyushin, Stanislav;
Haak, Stefan;
Ingold, Barbara;
Kulig, Paulina;
Heppner, Frank L.;
Navarini, Alexander A.;
Becher, Burkhard

Publication type:

Article

Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2239, doi. 10.1172/JCI58147

By:

Jung, Camille;
Meinzer, Ulrich;
Montcuquet, Nicolas;
Thachil, Elodie;
Château, Danielle;
Thiébaut, Raphaële;
Roy, Maryline;
Alnabhani, Ziad;
Berrebi, Dominique;
Dussaillant, Monique;
Pedruzzi, Eric;
Thenet, Sophie;
Cerf-Bensussan, Nadine;
Hugot, Jean-Pierre;
Barreau, Frederick

Publication type:

Article

Antigen-presenting cell-derived complement modulates graft-versus-host disease.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2234, doi. 10.1172/JCI61019

By:

Kwan, Wing-Hong;
Hashimoto, Daigo;
Paz-Artal, Estela;
Ostrow, Katya;
Greter, Melanie;
Raedler, Hugo;
Medof, M. Edward;
Merad, Miriam;
Heeger, Peter S.

Publication type:

Article

IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2221, doi. 10.1172/JCI59535

By:

Liu, Daofeng;
Song, Liping;
Wei, Jie;
Courtney, Amy N.;
Gao, Xiuhua;
Marinova, Ekaterina;
Guo, Linjie;
Heczey, Andras;
Asgharzadeh, Shahab;
Kim, Eugene;
Dotti, Gianpietro;
Metelitsa, Leonid S.

Publication type:

Article

Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2141, doi. 10.1172/JCI61788

By:

Sauer, Aisha V.;
Morbach, Henner;
Brigida, Immacolata;
Ng, Yen-Shing;
Aiuti, Alessandro;
Meffre, Eric

Publication type:

Article

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2130, doi. 10.1172/JCI60006

By:

Vandevyver, Sofie;
Dejager, Lien;
Bogaert, Tom Van;
Kleyman, Anna;
Liu, Yusen;
Tuckermann, Jan;
Libert, Claude

Publication type:

Article

mTORC1 is essential for leukemia propagation but not stem cell self-renewal.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2114, doi. 10.1172/JCI62279

By:

Hoshii, Takayuki;
Tadokoro, Yuko;
Naka, Kazuhito;
Ooshio, Takako;
Muraguchi, Teruyuki;
Sugiyama, Naoyuki;
Soga, Tomoyoshi;
Araki, Kimi;
Yamamura, Ken-ichi;
Hirao, Atsushi

Publication type:

Article

CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2165, doi. 10.1172/JCI61380

By:

Jian Hong;
Kaishun Hu;
Yunfei Yuan;
Yi Sang;
Qiangui Bu;
Guihua Chen;
Longjun Yang;
Binkui Li;
Pinzhu Huang;
Dongtai Chen;
Yi Liang;
Ruhua Zhang;
Jingxuan Pan;
Yi-Xin Zeng;
Tiebang Kang

Publication type:

Article

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2092, doi. 10.1172/JCI60144

By:

Hamidi, Tewfik;
Algül, Hana;
Cano, Carla Eliana;
Sandi, Maria José;
Molejon, Maria Inés;
Riemann, Marc;
Calvo, Ezequiel Luis;
Lomberk, Gwen;
Dagorn, Jean-Charles;
Weih, Falk;
Urrutia, Raul;
Schmid, Roland Michael;
Iovanna, Juan Lucio

Publication type:

Article

14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2079, doi. 10.1172/JCI59719

By:

Jing Jiang;
Balcerek, Joanna;
Rozenova, Krasimira;
Ying Cheng;
Bersenev, Alexey;
Chao Wu;
Yiwen Song;
Wei Tong

Publication type:

Article

Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2066, doi. 10.1172/JCI59735

By:

Battula, Venkata Lokesh;
Shi, Yuexi;
Evans, Kurt W.;
Rui-Yu Wang;
Spaeth, Erika L.;
Jacamo, Rodrigo O.;
Guerra, Rudy;
Sahin, Aysegul A.;
Marini, Frank C.;
Hortobagyi, Gabriel;
Mani, Sendurai A.;
Andreeff, Michael

Publication type:

Article

microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2054, doi. 10.1172/JCI62656

By:

Liu, Ning;
Williams, Andrew H.;
Maxeiner, Johanna M.;
Bezprozvannaya, Svetlana;
Shelton, John M.;
Richardson, James A.;
Bassel-Duby, Rhonda;
Olson, Eric N.

Publication type:

Article

Zona glomerulosa cells of the mouse adrenal cortex are intrinsic electrical oscillators.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2046, doi. 10.1172/JCI61996

By:

Changlong Hu;
Rusin, Craig G.;
Tan, Zhiyong;
Guagliardo, Nick A.;
Barrett, Paula Q.

Publication type:

Article

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2018, doi. 10.1172/JCI46231

By:

LaBelle, James L.;
Katz, Samuel G.;
Bird, Gregory H.;
Gavathiotis, Evripidis;
Stewart, Michelle L.;
Lawrence, Chelsea;
Fisher, Jill K.;
Godes, Marina;
Pitter, Kenneth;
Kung, Andrew L.;
Walensky, Loren D.

Publication type:

Article

Blood flow reprograms lymphatic vessels to blood vessels.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2006, doi. 10.1172/JCI57513

By:

Chiu-Yu Chen;
Bertozzi, Cara;
Zhiying Zou;
Yuan, Lijun;
Lee, John S.;
Lu, MinMin;
Stachelek, Stan J.;
Srinivasan, Sathish;
Guo, Lili;
Vincente, Andres;
Mericko, Patricia;
Levy, Robert J.;
Makinen, Taija;
Oliver, Guillermo;
Kahn, Mark L.

Publication type:

Article

Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1991, doi. 10.1172/JCI58832

By:

Felcht, Moritz;
Luck, Robert;
Schering, Alexander;
Seidel, Philipp;
Srivastava, Kshitij;
Hu, Junhao;
Bartol, Arne;
Kienast, Yvonne;
Vettel, Christiane;
Loos, Elias K.;
Kutschera, Simone;
Bartels, Susanne;
Appak, Sila;
Besemfelder, Eva;
Terhardt, Dorothee;
Chavakis, Emmanouil;
Wieland, Thomas;
Klein, Christian;
Thomas, Markus;
Uemura, Akiyoshi

Publication type:

Article

MicroRNA-181b regulates NF-&kgr;B-mediated vascular inflammation.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1973, doi. 10.1172/JCI61495

By:

Sun, Xinghui;
Icli, Basak;
Wara, Akm Khyrul;
Belkin, Nathan;
He, Shaolin;
Kobzik, Lester;
Hunninghake, Gary M.;
Vera, Miguel Pinilla;
Registry, Micu;
Blackwell, Timothy S.;
Baron, Rebecca M.;
Feinberg, Mark W.

Publication type:

Article

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2032, doi. 10.1172/JCI60132

By:

Yao, Hongwei;
Chung, Sangwoon;
Hwang, Jae-woong;
Rajendrasozhan, Saravanan;
Sundar, Isaac K.;
Dean, David A.;
McBurney, Michael W.;
Guarente, Leonard;
Gu, Wei;
Rönty, Mikko;
Kinnula, Vuokko L.;
Rahman, Irfan

Publication type:

Article

A conversation with Lloyd Hollingsworth Smith Jr.

Published in:

2012

By:

Neill, Ushma S.

Publication type:

Interview

Getting to the finish line with mTORC1-targeted therapy.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1970, doi. 10.1172/JCI64227

By:

Henske, Elizabeth

Publication type:

Article

Taming endothelial activation with a microRNA.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1967, doi. 10.1172/JCI63818

By:

Fish, Jason E.;
Cybulsky, Myron I.

Publication type:

Article

Therapeutic potential of a peptide targeting BCL-2 cell guardians in cancer.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1965, doi. 10.1172/JCI64120

By:

Adams, Jerry M.

Publication type:

Article

Telomere stability and carcinogenesis: an off-again, on-again relationship.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1962, doi. 10.1172/JCI63979

By:

Wanat, Jennifer J.;
Johnson, F. Brad

Publication type:

Article

Restoring balance to B cells in ADA deficiency.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1960, doi. 10.1172/JCI63782

By:

Prak, Eline T. Luning

Publication type:

Article

Malonyl-CoA: the regulator of fatty acid synthesis and oxidation.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1958, doi. 10.1172/JCI63967

By:

Foster, Daniel W.

Publication type:

Article

The molecular pathogenesis of head and neck squamous cell carcinoma.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 1951, doi. 10.1172/JCI59889

By:

Rothenberg, S. Michael;
Ellisen, Leif W.

Publication type:

Article