Works matching IS 00219738 AND DT 2011 AND VI 121 AND IP 6

Results: 50

The three R's of lung health and disease: repair, remodeling, and regeneration.

Published in:

2011

By:

Beers, Michael F.;
Morrisey, Edward E.

Publication type:

journal article

From probiotics to therapeutics: another step forward?

Published in:

2011

By:

Ghishan, Fayez K.;
Kiela, Pawel R.

Publication type:

journal article

Chronic lung allograft rejection and airway microvasculature: is HIF-1 the missing link?

Published in:

2011

By:

Wilkes, David S.

Publication type:

journal article

Neuroanatomy of body weight control: lessons learned from leptin.

Published in:

2011

By:

Williams, Diana L.;
Schwartz, Michael W.

Publication type:

journal article

Spotlight on childhood blindness.

Published in:

2011

By:

Sahel, José-Alain

Publication type:

journal article

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.

Published in:

2011

By:

Bezy, Olivier;
Tran, Thien T.;
Pihlajamäki, Jussi;
Suzuki, Ryo;
Emanuelli, Brice;
Winnay, Jonathan;
Mori, Marcelo A.;
Haas, Joel;
Biddinger, Sudha B.;
Leitges, Michael;
Goldfine, Allison B.;
Patti, Mary Elizabeth;
King, George L.;
Kahn, C. Ronald;
Pihlajamäki, Jussi

Publication type:

journal article

Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape.

Published in:

2011

By:

Lazaro, Estibaliz;
Kadie, Carl;
Stamegna, Pamela;
Shao Chong Zhang;
Gourdain, Pauline;
Lai, Nicole Y.;
Mei Zhang;
Martinez, Sergio A.;
Heckerman, David;
Le Gall, Sylvie;
Zhang, Shao Chong;
Zhang, Mei

Publication type:

journal article

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras.

Published in:

2011

By:

Wheeler, Lee Adam;
Trifonova, Radiana;
Vrbanac, Vladimir;
Basar, Emre;
McKernan, Shannon;
Zhan Xu;
Seung, Edward;
Deruaz, Maud;
Dudek, Tim;
Einarsson, Jon Ivar;
Yang, Linda;
Allen, Todd M.;
Luster, Andrew D.;
Tager, Andrew M.;
Dykxhoorn, Derek M.;
Lieberman, Judy;
Xu, Zhan

Publication type:

journal article

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling.

Published in:

2011

By:

Miller, Russell A.;
Qingwei Chu;
Le Lay, John;
Scherer, Philipp E.;
Ahima, Rexford S.;
Kaestner, Klaus H.;
Foretz, Marc;
Viollet, Benoit;
Birnbaum, Morris J.;
Chu, Qingwei

Publication type:

journal article

The targeted podocyte.

Published in:

2011

By:

Fogo, Agnes B.

Publication type:

journal article

Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation.

Published in:

2011

By:

Fujioka, Masato;
Tokano, Hisashi;
Fujioka, Keiko Shiina;
Okano, Hideyuki;
Edge, Albert S. B.

Publication type:

journal article

Epicutaneous challenge of orally immunized mice redirects antigen-specific gut-homing T cells to the skin.

Published in:

2011

By:

Oyoshi, Michiko K.;
Elkhal, Abdallah;
Scott, Jordan E.;
Wurbel, Marc-Andre;
Hornick, Jason L.;
Campbell, James J.;
Geha, Raif S.

Publication type:

journal article

Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke--induced emphysema in mice.

Published in:

Journal of Clinical Investigation, 2011, v. 121, n. 6, p. 2470, doi. 10.1172/JCI43881

By:

Clauss, Matthias;
Voswinckel, Robert;
Rajashekhar, Gangaraju;
Sigua, Ninotchka L.;
Fehrenbach, Heinz;
Rush, Natalia I.;
Schweitzer, Kelly S.;
Yildirim, Ali Ö.;
Kamocki, Krzysztof;
Fisher, Amanda J.;
Yuan Gu;
Safadi, Bilal;
Nikam, Sandeep;
Hubbard, Walter C.;
Tuder, Rubin M.;
Twigg, Homer L.;
Presson, Robert G.;
Sethi, Sanjay;
Petrache, Irina

Publication type:

Article

A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection.

Published in:

2011

By:

Montamat-Sicotte, Damien J.;
Millington, Kerry A.;
Willcox, Carrie R.;
Hingley-Wilson, Suzie;
Hackforth, Sarah;
Innes, John;
Onn Min Kon;
Lammas, David A.;
Minnikin, David E.;
Besra, Gurdyal S.;
Willcox, Benjamin E.;
Lalvani, Ajit;
Kon, Onn Min

Publication type:

journal article

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque.

Published in:

2011

By:

Rotger, Margalida;
Dalmau, Judith;
Rauch, Andri;
McLaren, Paul;
Bosinger, Steven E.;
Martinez, Raquel;
Sandler, Netanya G.;
Roque, Annelys;
Liebner, Julia;
Battegay, Manuel;
Bernasconi, Enos;
Descombes, Patrick;
Erkizia, Itziar;
Fellay, Jacques;
Hirschel, Bernard;
Miró, Jose M.;
Palou, Eduard;
Hoffmann, Matthias;
Massanella, Marta;
Julià Blanco

Publication type:

journal article

Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease.

Published in:

2011

By:

Yong-Hee Rhee;
Ji-Yun Ko;
Mi-Yoon Chang;
Sang-Hoon Yi;
Dohoon Kim;
Chun-Hyung Kim;
Jae-Won Shim;
A-Young Jo;
Byung-Woo Kim;
Hyunsu Lee;
Suk-Ho Lee;
Wonhee Suh;
Chang-Hwan Park;
Hyun-Chul Koh;
Yong-Sung Lee;
Lanza, Robert;
Kwang-Soo Kim;
Sang-Hun Lee;
Rhee, Yong-Hee;
Ko, Ji-Yun

Publication type:

journal article

Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes.

Published in:

2011

By:

Christodoulou, Constantina;
Longmire, Tyler A.;
Shen, Steven S.;
Bourdon, Alice;
Sommer, Cesar A.;
Gadue, Paul;
Spira, Avrum;
Gouon-Evans, Valerie;
Murphy, George J.;
Mostoslavsky, Gustavo;
Kotton, Darrell N.

Publication type:

journal article

Mitochondrial dysfunction in patients with primary congenital insulin resistance.

Published in:

2011

By:

Sleigh, Alison;
Raymond-Barker, Philippa;
Thackray, Kerrie;
Porter, David;
Hatunic, Mensud;
Vottero, Alessandra;
Burren, Christine;
Mitchell, Catherine;
McIntyre, Martin;
Brage, Soren;
Carpenter, T. Adrian;
Murgatroyd, Peter R.;
Brindle, Kevin M.;
Kemp, Graham J.;
O'Rahilly, Stephen;
Semple, Robert K.;
Savage, David B.

Publication type:

journal article

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.

Published in:

2011

By:

Qing-Jun Zhang;
Hou-Zao Chen;
Lin Wang;
De-Pei Liu;
Hill, Joseph A.;
Zhi-Ping Liu;
Zhang, Qing-Jun;
Chen, Hou-Zao;
Wang, Lin;
Liu, De-Pei;
Liu, Zhi-Ping

Publication type:

journal article

A dual role for the immune response in a mouse model of inflammation-associated lung cancer.

Published in:

2011

By:

Dougan, Michael;
Danan Li;
Neuberg, Donna;
Mihm, Martin;
Googe, Paul;
Kwok-Kin Wong;
Dranoff, Glenn;
Li, Danan;
Wong, Kwok-Kin

Publication type:

journal article

The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice.

Published in:

2011

By:

Bell, Christie L.;
Vandenberghe, Luk H.;
Bell, Peter;
Limberis, Maria P.;
Guang-Ping Gao;
Van Vliet, Kim;
Agbandje-McKenna, Mavis;
Wilson, James M.;
Gao, Guang-Ping

Publication type:

journal article

Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice.

Published in:

2011

By:

Yingjie Wu;
Chengyu Liu;
Hui Sun;
Vijayakumar, Archana;
Raeisi Giglou, Pejman;
Ruifang Qiao;
Oppenheimer, Joshua;
Yakar, Shoshana;
LeRoith, Derek;
Wu, Yingjie;
Liu, Chengyu;
Sun, Hui;
Giglou, Pejman Raeisi;
Qiao, Ruifang

Publication type:

journal article

Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice.

Published in:

2011

By:

Scott, Michael M.;
Williams, Kevin W.;
Rossi, Jari;
Lee, Charlotte E.;
Elmquist, Joel K.

Publication type:

journal article

Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload.

Published in:

2011

By:

Koitabashi, Norimichi;
Danner, Thomas;
Zaiman, Ari L.;
Pinto, Yigal M.;
Rowell, Janelle;
Mankowski, Joseph;
Dou Zhang;
Nakamura, Taishi;
Takimoto, Eiki;
Kass, David A.;
Zhang, Dou

Publication type:

journal article

Engagement of S1P₁-degradative mechanisms leads to vascular leak in mice.

Published in:

2011

By:

Myat Lin Oo;
Sung-Hee Chang;
Thangada, Shobha;
Ming-Tao Wu;
Rezaul, Karim;
Blaho, Victoria;
Sun-Il Hwang;
Han, David K.;
Hla, Timothy;
Oo, Myat Lin;
Chang, Sung-Hee;
Wu, Ming-Tao;
Hwang, Sun-Il

Publication type:

journal article

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.

Published in:

2011

By:

Gödel, Markus;
Hartleben, Björn;
Herbach, Nadja;
Shuya Liu;
Zschiedrich, Stefan;
Shun Lu;
Debreczeni-Mór, Andrea;
Lindenmeyer, Maja T.;
Rastaldi, Maria-Pia;
Hartleben, Götz;
Wiech, Thorsten;
Fornoni, Alessia;
Nelson, Robert G.;
Kretzler, Matthias;
Wanke, Rüdiger;
Pavenstädt, Hermann;
Kerjaschki, Dontscho;
Cohen, Clemens D.;
Hall, Michael N.;
Rüegg, Markus A.

Publication type:

journal article

Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts.

Published in:

2011

By:

Xiaohua Ni;
Yonggang Zhang;
Ribas, Judit;
Chowdhury, Wasim H.;
Castanares, Mark;
Zhewei Zhang;
Laiho, Marikki;
DeWeese, Theodore L.;
Lupold, Shawn E.;
Ni, Xiaohua;
Zhang, Yonggang;
Zhang, Zhewei

Publication type:

journal article

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice.

Published in:

2011

By:

Long Wang51;
Jie Fan;
Thompson, Linda F.;
Yi Zhang;
Shin, Tahiro;
Curiel, Tyler J.;
Bin Zhang;
Wang, Long;
Fan, Jie;
Zhang, Yi;
Zhang, Bin

Publication type:

journal article

Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.

Published in:

2011

By:

Aucagne, Romain;
Droin, Nathalie;
Paggetti, Jérôme;
Lagrange, Brice;
Largeot, Anne;
Hammann, Arlette;
Bataille, Amandine;
Martin, Laurent;
Kai-Ping Yan;
Fenaux, Pierre;
Losson, Régine;
Solary, Eric;
Bastie, Jean-Noël;
Delva, Laurent;
Paggetti, Jérôme;
Yan, Kai-Ping;
Losson, Régine;
Bastie, Jean-Noël

Publication type:

journal article

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients.

Published in:

2011

By:

Baitsch, Lukas;
Baumgaertner, Petra;
Devêvre, Estelle;
Raghav, Sunil K.;
Legat, Amandine;
Barba, Leticia;
Wieckowski, Sébastien;
Bouzourene, Hanifa;
Deplancke, Bart;
Romero, Pedro;
Rufer, Nathalie;
Speiser, Daniel E.;
Devêvre, Estelle;
Wieckowski, Sébastien

Publication type:

journal article

Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection.

Published in:

2011

By:

Xinguo Jiang;
Khan, Mohammad A.;
Wen Tian;
Beilke, Joshua;
Natarajan, Ramesh;
Kosek, Jon;
Yoder, Mervin C.;
Semenza, Gregg L.;
Nicolls, Mark R.;
Jiang, Xinguo;
Tian, Wen

Publication type:

journal article

Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice.

Published in:

2011

By:

Behrens, Edward M.;
Canna, Scott W.;
Slade, Katharine;
Rao, Sheila;
Kreiger, Portia A.;
Paessler, Michele;
Kambayashi, Taku;
Koretzky, Gary A.

Publication type:

journal article

CD8⁺ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung.

Published in:

2011

By:

Piet, Berber;
de Bree, Godelieve J.;
Smids-Dierdorp, Barbara S.;
van der Loos, Chris M.;
Remmerswaal, Ester B. M.;
von der Thüsen, Jan H.;
van Haarst, Jan M. W.;
Eerenberg, Jan P.;
Brinke, Anja ten;
Wim van der Bij;
Wim Timens;
van Lier, René A. W.;
Jonkers, René E.;
von der Thüsen, Jan H;
ten Brinke, Anja;
van der Bij, Wim;
Timens, Wim;
van Lier, René A W;
Jonkers, René E

Publication type:

journal article

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.

Published in:

2011

By:

Fang Yan;
Hanwei Cao;
Cover, Timothy L.;
Washington, M. Kay;
Yan Shi;
LinShu Liu;
Chaturvedi, Rupesh;
Peek Jr., Richard M.;
Wilson, Keith T.;
Polk, D. Brent;
Yan, Fang;
Cao, Hanwei;
Shi, Yan;
Liu, LinShu;
Peek, Richard M Jr

Publication type:

journal article

Autoimmunity in MFG-E8-deficient mice is associated with altered trafficking and enhanced cross-presentation of apoptotic cell antigens.

Published in:

2011

By:

YuFeng Peng;
Elkon, Keith B.;
Peng, YuFeng

Publication type:

journal article

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.

Published in:

2011

By:

Jeansson, Marie;
Gawlik, Alexander;
Anderson, Gregory;
Chengjin Li;
Kerjaschki, Dontscho;
Henkelman, Mark;
Quaggin, Susan E.;
Li, Chengjin

Publication type:

journal article

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.

Published in:

2011

By:

Inoki, Ken;
Mori, Hiroyuki;
Junying Wang;
Suzuki, Tsukasa;
SungKi Hong;
Sei Yoshida;
Blattner, Simone M.;
Ikenoue, Tsuneo;
Rüegg, Markus A.;
Hall, Michael N.;
Kwiatkowski, David J.;
Rastaldi, Maria P.;
Huber, Tobias B.;
Kretzler, Matthias;
Holzman, Lawrence B.;
Wiggins, Roger C.;
Kun-Liang Guan;
Wang, Junying;
Hong, SungKi;
Yoshida, Sei

Publication type:

journal article

Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice.

Published in:

2011

By:

Boldt, Karsten;
Mans, Dorus A.;
Jungyeon Won;
van Reeuwijk, Jeroen;
Vogt, Andreas;
Kinkl, Norbert;
Letteboer, Stef J. F.;
Hicks, Wanda L.;
Hurd, Ron E.;
Jürgen K. Naggert;
Texier, Yves;
den Hollander, Anneke I.;
Koenekoop, Robert K.;
Bennett, Jean;
Cremers, Frans P. M.;
Gloeckner, Christian J.;
Nishina, Patsy M.;
Roepman, Ronald;
Ueffing, Marius;
Won, Jungyeon

Publication type:

journal article

The human visual cortex responds to gene therapy-mediated recovery of retinal function.

Published in:

2011

By:

Ashtari, Manzar;
Cyckowski, Laura L.;
Monroe, Justin F.;
Marshall, Kathleen A.;
Chung, Daniel C.;
Auricchio, Alberto;
Simonelli, Francesca;
Leroy, Bart P.;
Maguire, Albert M.;
Shindler, Kenneth S.;
Bennett, Jean

Publication type:

journal article

The yin, the yang, and the angiopoietin-1.

Published in:

2011

By:

Saharinen, Pipsa;
Alitalo, Kari

Publication type:

journal article

Circadian rhythms, sleep, and metabolism.

Published in:

Journal of Clinical Investigation, 2011, v. 121, n. 6, p. 2133, doi. 10.1172/JCI46043

By:

Wenyu Huang;
Ramsey, Kathryn Moynihan;
Marcheva, Biliana;
Bass, Joseph

Publication type:

Article

Gut microbiome, obesity, and metabolic dysfunction.

Published in:

2011

By:

Tilg, Herbert;
Kaser, Arthur

Publication type:

journal article

Dynamics of insulin secretion and the clinical implications for obesity and diabetes.

Published in:

2011

By:

Seino, Susumu;
Shibasaki, Tadao;
Minami, Kohtaro

Publication type:

journal article

Inflammatory links between obesity and metabolic disease.

Published in:

2011

By:

Lumeng, Carey N.;
Saltiel, Alan R.

Publication type:

journal article

The role of lipid droplets in metabolic disease in rodents and humans.

Published in:

2011

By:

Greenberg, Andrew S.;
Coleman, Rosalind A.;
Kraemer, Fredric B.;
McManaman, James L.;
Obin, Martin S.;
Puri, Vishwajeet;
Qing-Wu Yan;
Miyoshi, Hideaki;
Mashek, Douglas G.;
Yan, Qing-Wu

Publication type:

journal article

Adipose tissue remodeling and obesity.

Published in:

2011

By:

Kai Sun;
Kusminski, Christine M.;
Scherer, Philipp E.;
Sun, Kai

Publication type:

journal article

Sixteen years and counting: an update on leptin in energy balance.

Published in:

2011

By:

Gautron, Laurent;
Elmquist, Joel K.

Publication type:

journal article

Genetic approaches to understanding human obesity.

Published in:

2011

By:

Ramachandrappa, Shwetha;
Farooqi, I. Sadaf

Publication type:

journal article

Digging deeper into obesity.

Published in:

2011

By:

Ahima, Rexford S.

Publication type:

research

Duke/UNC to helm the JCI in March 2012.

Published in:

2011

By:

Neill, Ushma S.

Publication type:

Interview