Works matching IS 00219738 AND DT 2007 AND VI 117

Results: 598

OX40-OX40L interactions: a promising therapeutic target for allergic diseases?

Published in:

2007

By:

Wang, Yui-Hsi;
Liu, Yong-Jun

Publication type:

journal article

Milk fat globule-EGF factor 8/lactadherin plays a crucial role in maintenance and repair of murine intestinal epithelium.

Published in:

2007

By:

Bu, Heng-Fu;
Zuo, Xiu-Li;
Wang, Xiao;
Ensslin, Michael A;
Koti, Vjola;
Hsueh, Wei;
Raymond, Adam S;
Shur, Barry D;
Tan, Xiao-Di

Publication type:

journal article

Bone marrow-derived circulating progenitor cells fail to transdifferentiate into adipocytes in adult adipose tissues in mice.

Published in:

2007

By:

Koh, Young Jun;
Kang, Shinae;
Lee, Hyuek Jong;
Choi, Tae-Saeng;
Lee, Ho Sub;
Cho, Chung-Hyun;
Koh, Gou Young

Publication type:

journal article

Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling.

Published in:

2007

By:

Hu, Kebin;
Wu, Chuanyue;
Mars, Wendy M;
Liu, Youhua

Publication type:

journal article

FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.

Published in:

2007

By:

Zuo, Tao;
Liu, Runhua;
Zhang, Huiming;
Chang, Xing;
Liu, Yan;
Wang, Lizhong;
Zheng, Pan;
Liu, Yang

Publication type:

journal article

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.

Published in:

2007

By:

Calzascia, Thomas;
Pellegrini, Marc;
Hall, Håkan;
Sabbagh, Laurent;
Ono, Nobuyuki;
Elford, Alisha R;
Mak, Tak W;
Ohashi, Pamela S

Publication type:

journal article

Recombinant adeno-associated virus vectors induce functionally impaired transgene product-specific CD8+ T cells in mice.

Published in:

2007

By:

Lin, Shih-Wen;
Hensley, Scott E;
Tatsis, Nia;
Lasaro, Marcio O;
Ertl, Hildegund C J

Publication type:

journal article

Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans.

Published in:

2007

By:

Panicot-Dubois, Laurence;
Thomas, Grace M;
Furie, Barbara C;
Furie, Bruce;
Lombardo, Dominique;
Dubois, Christophe

Publication type:

journal article

The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3940, doi. 10.1172/JCI32741

By:

Jun-ichi Hanai;
Peirang Cao;
Tanksale, Preeti;
Imamura, Shintaro;
Koshimizu, Eriko;
Jinghui Zhao;
Kishi, Shuji;
Yamashita, Michiaki;
Phillips, Paul S.;
Sukhatme, Vikas P.;
Lecker, Stewart H.

Publication type:

Article

CD200 is induced by ERK and is a potential therapeutic target in melanoma.

Published in:

2007

By:

Petermann, Kimberly B.;
Rozenberg, Gabriela I.;
Zedek, Daniel;
Groben, Pamela;
McKinnon, Karen;
Buehler, Christin;
Kim, William Y.;
Shields, Janiel M.;
Penland, Shannon;
Bear, James E.;
Thomas, Nancy E.;
Serody, Jonathan S.;
Sharpless, Norman E.

Publication type:

journal article

The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.

Published in:

2007

By:

Suliman, Hagir B;
Carraway, Martha Sue;
Ali, Abdelwahid S;
Reynolds, Chrystal M;
Welty-Wolf, Karen E;
Piantadosi, Claude A

Publication type:

journal article

Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.

Published in:

2007

By:

Burkart, Eileen M;
Sambandam, Nandakumar;
Han, Xianlin;
Gross, Richard W;
Courtois, Michael;
Gierasch, Carolyn M;
Shoghi, Kooresh;
Welch, Michael J;
Kelly, Daniel P

Publication type:

journal article

An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic.

Published in:

2007

By:

Fernández, Ariel;
Sanguino, Angela;
Peng, Zhenghong;
Ozturk, Eylem;
Chen, Jianping;
Crespo, Alejandro;
Wulf, Sarah;
Shavrin, Aleksander;
Qin, Chaoping;
Ma, Jianpeng;
Trent, Jonathan;
Lin, Yvonne;
Han, Hee-Dong;
Mangala, Lingegowda S;
Bankson, James A;
Gelovani, Juri;
Samarel, Allen;
Bornmann, William;
Sood, Anil K;
Lopez-Berestein, Gabriel

Publication type:

journal article

Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons.

Published in:

2007

By:

Rao, Yan;
Liu, Zhong-Wu;
Borok, Erzsebet;
Rabenstein, Rebecca L;
Shanabrough, Marya;
Lu, Min;
Picciotto, Marina R;
Horvath, Tamas L;
Gao, Xiao-Bing

Publication type:

journal article

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.

Published in:

2007

By:

Hu, Chang-yun;
Rodriguez-Pinto, Daniel;
Du, Wei;
Ahuja, Anupama;
Henegariu, Octavian;
Wong, F Susan;
Shlomchik, Mark J;
Wen, Li

Publication type:

journal article

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Published in:

2007

By:

Gao, Sizhi Paul;
Mark, Kevin G;
Leslie, Kenneth;
Pao, William;
Motoi, Noriko;
Gerald, William L;
Travis, William D;
Bornmann, William;
Veach, Darren;
Clarkson, Bayard;
Bromberg, Jacqueline F

Publication type:

journal article

OX40-OX40L interactions: a promising therapeutic target for allergic diseases?

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3655, doi. 10.1172/JCI34182

By:

Yui-Hsi Wang;
Yong-Jun Liu

Publication type:

Article

Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 4022, doi. 10.1172/JCI32829

By:

Yan Rao;
Zhong-Wu Liu;
Borok, Erzsebet;
Rabenstein, Rebecca L.;
Shanabrough, Marya;
Min Lu;
Picciotto, Marina R.;
Horvath, Tamas L.;
Xiao-Bing Gao

Publication type:

Article

Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.

Published in:

2007

By:

Liu, Tianju;
Chung, Myoung Ja;
Ullenbruch, Matthew;
Yu, Hongfeng;
Jin, Hong;
Hu, Biao;
Choi, Yoon Young;
Ishikawa, Fuyuki;
Phan, Sem H

Publication type:

journal article

The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.

Published in:

2007

By:

Hanai, Jun-ichi;
Cao, Peirang;
Tanksale, Preeti;
Imamura, Shintaro;
Koshimizu, Eriko;
Zhao, Jinghui;
Kishi, Shuji;
Yamashita, Michiaki;
Phillips, Paul S;
Sukhatme, Vikas P;
Lecker, Stewart H

Publication type:

journal article

PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis.

Published in:

2007

By:

Belguise, Karine;
Sonenshein, Gail E.

Publication type:

journal article

The parathyroid is a target organ for FGF23 in rats.

Published in:

2007

By:

Ben-Dov, Iddo Z.;
Galitzer, Hillel;
Lavi-Moshayoff, Vardit;
Goetz, Regina;
Kuro-o, Makoto;
Mohammadi, Moosa;
Sirkis, Roy;
Naveh-Many, Tally;
Silver, Justin

Publication type:

journal article

An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 4044, doi. 10.1172/JCI32373

By:

Ariel Fernández;
Angela Sanguino;
Zhenghong Peng;
Eylem Ozturk;
Jianping Chen;
Alejandro Crespo;
Sarah Wulf;
Aleksander Shavrin;
Chaoping Qin;
Jianpeng Ma;
Jonathan Trent;
Yvonne Lin;
Hee-Dong Han;
Lingegowda S. Mangala;
James A. Bankson;
Juri Gelovani;
Allen Samarel;
William Bornmann;
Anil K. Sood;
Gabriel Lopez-Berestein

Publication type:

Article

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

Published in:

2007

By:

Regard, Jean B.;
Kataoka, Hiroshi;
Cano, David A.;
Camerer, Eric;
Liya Yin;
Yao-Wu Zheng;
Scanlan, Thomas S.;
Hebrok, Matthias;
Coughlin, Shaun R.;
Yin, Liya;
Zheng, Yao-Wu

Publication type:

journal article

Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene.

Published in:

2007

By:

Selva, David M.;
Hogeveen, Kevin N.;
Innis, Sheila M.;
Hammond, Geoffrey L.

Publication type:

journal article

Recombinant adeno-associated virus vectors induce functionally impaired transgene product--specific CD8+ T cells in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3958, doi. 10.1172/JCI33138

By:

Shih-Wen Lin;
Hensley, Scott E.;
Tatsis, Nia;
Lasaro, Marcio O.;
Ertl, Hildegund C. J.

Publication type:

Article

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

Published in:

2007

By:

Yvan-Charvet, Laurent;
Ranalletta, Mollie;
Nan Wang;
Seongah Han;
Terasaka, Naoki;
Rong Li;
Welch, Carrie;
Tall, Alan R.;
Wang, Nan;
Han, Seongah;
Li, Rong

Publication type:

journal article

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland.

Published in:

2007

By:

Sansone, Pasquale;
Storci, Gianluca;
Tavolari, Simona;
Guarnieri, Tiziana;
Giovannini, Catia;
Taffurelli, Mario;
Ceccarelli, Claudio;
Santini, Donatella;
Paterini, Paola;
Marcu, Kenneth B.;
Chieco, Pasquale;
Bonafè, Massimiliano;
Bonafè, Massimiliano

Publication type:

journal article

Nuclear receptors PPARβ/δ and PPARα direct distinct metabolic regulatory programs in the mouse heart.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3930, doi. 10.1172/JCI32578

By:

Burkart, Eileen M.;
Sambandam, Nandakumar;
Xianlin Han;
Gross, Richard W.;
Courtois, Michael;
Gierasch, Carolyn M.;
Shoghi, Kooresh;
Welch, Michael J.;
Kelly, Daniel P.

Publication type:

Article

Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri.

Published in:

2007

By:

Jurisicova, Andrea;
Taniuchi, Asako;
Han Li;
Yuan Shang;
Antenos, Monica;
Detmar, Jacqui;
Jing Xu;
Matikainen, Tiina;
Benito^Hernández, Adalberto;
Nunez, Gabriel;
Casper, Robert F.;
Li, Han;
Shang, Yuan;
Xu, Jing;
Benito Hernández, Adalberto

Publication type:

journal article

Deletion of TLR5 results in spontaneous colitis in mice.

Published in:

2007

By:

Vijay-Kumar, Matam;
Sanders, Catherine J.;
Taylor, Rebekah T.;
Kumar, Amrita;
Aitken, Jesse D.;
Sitaraman, Shanthi V.;
Neish, Andrew S.;
ematsu, Satoshi;
Akira, Shizuo;
Williams, Ifor R.;
Gewirtz, Andrew T.;
Uematsu, Satoshi

Publication type:

journal article

Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy.

Published in:

2007

By:

Wheeler, Thurman M.;
Lueck, John D.;
Swanson, Maurice S.;
Dirksen, Robert T.;
Thornton, Charles A.

Publication type:

journal article

von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.

Published in:

2007

By:

Hickey, Michele M.;
Lam, Jennifer C.;
Bezman, Natalie A.;
Rathmell, W. Kimryn;
Simon, M. Celeste

Publication type:

journal article

Telomerase activity is required for bleomycininduced pulmonary fibrosis in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3800, doi. 10.1172/JCI32369

By:

Tianju Liu;
Myoung Ja Chung;
Ullenbruch, Matthew;
Hongfeng Yu;
Hong Jin;
Biao Hu;
Yoon Young Choi;
Fuyuki Ishikawa;
Sem H. Phan

Publication type:

Article

Nonviral delivery of synthetic siRNAs in vivo.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3623, doi. 10.1172/JCI33494

By:

Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis.

Published in:

2007

By:

Babu, Ashok N.;
Murakawa, Tomohiro;
Thurman, Joshua M.;
Miller, Edmund J.;
Henson, Peter M.;
Zamora, Martin R.;
Voelkel, Norbert F.;
Nicolls, Mark R.

Publication type:

journal article

STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3890, doi. 10.1172/JCI33010

By:

Zan Huang;
Richmond, Terri D.;
Muntean, Andrew G.;
Barber, Dwayne L.;
Weiss, Mitchell J.;
Crispino, John D.

Publication type:

Article

Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice.

Published in:

2007

By:

Shing, Danielle C.;
Trubia, Maurizio;
Marchesi, Francesco;
Radaelli, Enrico;
Belloni, Elena;
Tapinassi, Cinzia;
Scanziani, Eugenio;
Mecucci, Cristina;
Crescenzi, Barbara;
Lahortiga, Idoya;
Odero, Maria D.;
Zardo, Giuseppe;
Gruszka, Alicja;
Minucci, Saverio;
Di^Fiore, Pier Paolo;
Pelicci, Pier Giuseppe

Publication type:

journal article

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.

Published in:

2007

By:

Seshasayee, Dhaya;
Lee, Wyne P.;
Meijuan Zhou;
Jean Shu;
Suto, Eric;
Juan Zhang;
Diehl, Laurie;
Austin, Cary D.;
Gloria Meng, Y.;
Martha Tan;
Bullens, Sherron L.;
Seeber, Stefan;
Fuentes, Maria E.;
Labrijn, Aran F.;
Graus, Yvo M. F.;
Miller, Lisa A.;
Schelegle, Edward S.;
Hyde, Dallas M.;
Wu, Lawren C.;
Hymowitz, Sarah G.

Publication type:

journal article

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3857, doi. 10.1172/JCI32405

By:

Chang-yun Hu;
Rodriguez-Pinto, Daniel;
Wei Du;
Ahuja, Anupama;
Henegariu, Octavian;
Susan Wong, F.;
Shlomchik, Mark J.;
Li Wen

Publication type:

Article

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3846, doi. 10.1172/JCI31871

By:

Sizhi Paul Gao;
Mark, Kevin G.;
Leslie, Kenneth;
Pao, William;
Motoi, Noriko;
Gerald, William L.;
Travis, William D.;
Bornmann, William;
Veach, Darren;
Clarkson, Bayard;
Bromberg, Jacqueline F.

Publication type:

Article

Visual phenotype in Williams-Beuren syndrome challenges magnocellular theories explaining human neurodevelopmental visual cortical disorders.

Published in:

2007

By:

Castelo-Branco, Miguel;
Mendes, Mafalda;
Sebastião, Ana Raquel;
Reis, Aldina;
Soares, Mário;
Saraiva, Jorge;
Bernardes, Rui;
Flores, Raquel;
Pérez-Jurado, Luis;
Silva, Eduardo;
Sebastião, Ana Raquel;
Soares, Mário;
Pérez-Jurado, Luis

Publication type:

journal article

TNF-α is critical for antitumor but not antiviral T cell immunity in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3833, doi. 10.1172/JCI32567

By:

Calzascia, Thomas;
Pellegrini, Marc;
Hall, Håkan;
Sabbagh, Laurent;
Ono, Nobuyuki;
Elford, Alisha R.;
Mak, Tak W.;
Ohashi, Pamela S.

Publication type:

Article

Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor--related protein 1--mediated integrin signaling.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3821, doi. 10.1172/JCI32301

By:

Kebin Hu;
Chuanyue Wu;
Mars, Wendy M.;
Youhua Liu

Publication type:

Article

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.

Published in:

2007

By:

Higgins, Debra F.;
Kimura, Kuniko;
Bernhardt, Wanja M.;
Shrimanker, Nikita;
Akai, Yasuhiro;
Hohenstein, Bernd;
Saito, Yoshihiko;
Johnson, Randall S.;
Kretzler, Matthias;
Cohen, Clemens D.;
Eckardt, Kai-Uwe;
Iwano, Masayuki;
Haase, Volker H.

Publication type:

journal article

Bone marrow--derived circulating progenitor cells fail to transdifferentiate into adipocytes in adult adipose tissues in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3684, doi. 10.1172/JCI32504

By:

Young Jun Koh;
Shinae Kang;
Hyuek Jong Lee;
Tae-Saeng Choi;
Ho Sub Lee;
Chung-Hyun Cho;
Gou Young Koh

Publication type:

Article

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3786, doi. 10.1172/JCI32285

By:

Gasse, Pamela;
Mary, Caroline;
Guenon, Isabelle;
Noulin, Nicolas;
Charron, Sabine;
Schnyder-Candrian, Silvia;
Schnyder, Bruno;
Akira, Shizuo;
Quesniaux, Valérie F. J.;
Lagente, Vincent;
Ryffel, Bernhard;
Couillin, Isabelle

Publication type:

Article

The weight of cell identity.

Published in:

2007

By:

Scadden, David T.

Publication type:

journal article

FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3765, doi. 10.1172/JCI32538

By:

Tao Zuo;
Runhua Liu;
Huiming Zhang;
Xing Chang;
Yan Liu;
Lizhong Wang;
Pan Zheng;
Yang Liu

Publication type:

Article

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3753, doi. 10.1172/JCI32481

By:

Xiuwei Tang;
Yucui Zhu;
Lydia Han;
Kim, Arianna L.;
Kopelovich, Levy;
Bickers, David R.;
Athar, Mohammad

Publication type:

Article