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Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1.
Published in:
Journal of Clinical Investigation, 2021, v. 131, n. 4, p. 1, doi. 10.1172/jci141799
By:
- Petrosino, Jennifer M.;
- Longenecker, Jacob Z.;
- Ramkumar, Srinivasagan;
- Xianyao Xu;
- Dorn, Lisa E.;
- Bratasz, Anna;
- Lianbo Yu;
- Maurya, Santosh;
- Tolstikov, Vladimir;
- Bussberg, Valerie;
- Janssen, M. L.;
- Periasamy, Muthu;
- Kiebish, Michael A.;
- Duester, Gregg;
- von Lintig, Johannes;
- Ziouzenkova, Ouliana;
- Accornero, Federica
Publication type:
Article
Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice.
Published in:
2021
By:
- Perampalam, Pirunthan;
- Hassan, Haider M.;
- Lilly, Grace E.;
- Passos, Daniel T.;
- Torchia, Joseph;
- Kiser, Patti K.;
- Bozovic, Andrea;
- Kulasingam, Vathany;
- Dick, Frederick A.
Publication type:
journal article
Active bacterial modification of the host environment through RNA polymerase II inhibition.
Published in:
Journal of Clinical Investigation, 2021, v. 131, n. 4, p. 1, doi. 10.1172/jci140333
By:
- Ambite, Inès;
- Filenko, Nina A.;
- Zaldastanishvili, Elisabed;
- Butler, Daniel S. C.;
- Thi Hien Tran;
- Chaudhuri, Arunima;
- Esmaeili, Parisa;
- Ahmadi, Shahram;
- Paul, Sanchari;
- Wullt, Björn;
- Putze, Johannes;
- Chen, Swaine L.;
- Dobrindt, Ulrich;
- Svanborg, Catharina
Publication type:
Article
Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis.
Published in:
2021
By:
- Fan, Liyan;
- Sweet, David R.;
- Prosdocimo, Domenick A.;
- Vinayachandran, Vinesh;
- Chan, Ernest R.;
- Zhang, Rongli;
- Ilkayeva, Olga;
- Yuan Lu;
- Keerthy, Komal S.;
- Booth, Chloe E.;
- Newgard, Christopher B.;
- Jain, Mukesh K.;
- Lu, Yuan
Publication type:
journal article
Severe insulin resistance syndromes.
Published in:
2021
By:
- Angelidi, Angeliki M.;
- Filippaios, Andreas;
- Mantzoros, Christos S.
Publication type:
journal article
Testosterone replacement in aging men: an evidence-based patient-centric perspective.
Published in:
Journal of Clinical Investigation, 2021, v. 131, n. 4, p. 1, doi. 10.1172/jci146607
By:
- Bhasin, Shalender
Publication type:
Article
Paracardial fat and vitamin A: a mechanism for regulating exercise performance.
Published in:
2021
By:
- Joseph, Leroy C.;
- Morrow, John P.
Publication type:
journal article
Gastrointestinal motility disorders in neurologic disease.
Published in:
2021
By:
- Camilleri, Michael
Publication type:
journal article
Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells.
Published in:
Journal of Clinical Investigation, 2021, v. 131, n. 4, p. 1, doi. 10.1172/jci143137
By:
- Mingcan Yu;
- Pal, Subhashis;
- Paterson, Cameron W.;
- Jau-Yi Li;
- Tyagi, Abdul Malik;
- Adams, Jonathan;
- Coopersmith, Craig M.;
- Weitzmann, M. Neale;
- Pacifici, Roberto
Publication type:
Article
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus.
Published in:
2021
By:
- Vlahava, Virginia-Maria;
- Murrell, Isa;
- Lihui Zhuang;
- Aicheler, Rebecca J.;
- Lim, Eleanor;
- Miners, Kelly L.;
- Ladell, Kristin;
- Suárez, Nicolás M.;
- Price, David A.;
- Davison, Andrew J.;
- Wilkinson, Gavin W. G.;
- Wills, Mark R.;
- Weekes, Michael P.;
- Wang, Eddie C. Y.;
- Stanton, Richard J.;
- Zhuang, Lihui;
- Wilkinson, Gavin Wg;
- Wang, Eddie Cy
Publication type:
journal article
Research gaps in medical treatment of transgender/nonbinary people.
Published in:
2021
By:
- Safer, Joshua D.
Publication type:
journal article
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders.
Published in:
2021
By:
- Jia Li;
- Fredericks, Maureen;
- Cannel, Marishka;
- Wang, Kathryn;
- Sako, Dianne;
- Maguire, Michelle C.;
- Grenha, Rosa;
- Liharska, Katia;
- Krishnan, Lavanya;
- Bloom, Troy;
- Belcheva, Elitza P.;
- Martinez, Pedro A.;
- Castonguay, Roselyne;
- Keates, Sarah;
- Alexander, Mark J.;
- Hyunwoo Choi;
- Grinberg, Asya V.;
- Pearsall, R. Scott;
- Oh, Paul;
- Kumar, Ravindra
Publication type:
journal article
Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer.
Published in:
2021
By:
- Shidong Lv;
- Qiong Song;
- Guang Chen;
- Erdong Cheng;
- Wei Chen;
- Cole, Ryan;
- Zeyu Wu;
- Pascal, Laura E.;
- Ke Wang;
- Wipf, Peter;
- Nelson, Joel B.;
- Qiang Wei;
- Wenhua Huang;
- Zhou Wang;
- Lv, Shidong;
- Song, Qiong;
- Chen, Guang;
- Cheng, Erdong;
- Chen, Wei;
- Wu, Zeyu
Publication type:
journal article
MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT.
Published in:
2021
By:
- Tao Shen;
- Wei Wang;
- Wolong Zhou;
- Coleman, Ilsa;
- Qinbo Cai;
- Bingning Dong;
- Ittmann, Michael M.;
- Creighton, Chad J.;
- Yingnan Bian;
- Yanling Meng;
- Rowley, David R.;
- Nelson, Peter S.;
- Moore, David D.;
- Feng Yang;
- Shen, Tao;
- Wang, Wei;
- Zhou, Wolong;
- Cai, Qinbo;
- Dong, Bingning;
- Bian, Yingnan
Publication type:
journal article
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
Published in:
Journal of Clinical Investigation, 2021, v. 131, n. 4, p. 1, doi. 10.1172/jci140299
By:
- McQuattie-Pimentel, Alexandra C.;
- Ziyou Ren;
- Joshi, Nikita;
- Watanabe, Satoshi;
- Stoeger, Thomas;
- Chi, Monica;
- Ziyan Lu;
- Sichizya, Lango;
- Aillon, Raul Piseaux;
- Ching-I Chen;
- Soberanes, Saul;
- Zhangying Chen;
- Reyfman, Paul A.;
- Walter, James M.;
- Anekalla, Kishore R.;
- Davis, Jennifer M.;
- Helmin, Kathryn A.;
- Runyan, Constance E.;
- Abdala-Valencia, Hiam;
- Nam, Kiwon
Publication type:
Article
Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes.
Published in:
2021
By:
- Akiko Nagamachi;
- Akinori Kanai;
- Megumi Nakamura;
- Hiroshi Okuda;
- Akihiko Yokoyama;
- Satoru Shinriki;
- Hirotaka Matsui;
- Toshiya Inaba;
- Nagamachi, Akiko;
- Kanai, Akinori;
- Nakamura, Megumi;
- Okuda, Hiroshi;
- Yokoyama, Akihiko;
- Shinriki, Satoru;
- Matsui, Hirotaka;
- Inaba, Toshiya
Publication type:
journal article
Bone marrow niche ATP levels determine leukemia-initiating cell activity via P2X7 in leukemic models.
Published in:
2021
By:
- Xiaoxiao He;
- Jiangbo Wan;
- Xiaona Yang;
- Xiuze Zhang;
- Dan Huang;
- Xie Li;
- Yejun Zou;
- Chiqi Chen;
- Zhuo Yu;
- Li Xie;
- Yaping Zhang;
- Ligen Liu;
- Shangang Li;
- Yuzheng Zhao;
- Hongfang Shao;
- Ye Yu;
- Junke Zheng;
- He, Xiaoxiao;
- Wan, Jiangbo;
- Yang, Xiaona
Publication type:
journal article
PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury.
Published in:
2021
By:
- Triantafyllou, Evangelos;
- Gudd, Cathrin L. C.;
- Mawhin, Marie-Anne;
- Husbyn, Hannah C.;
- Trovato, Francesca M.;
- Siggins, Matthew K.;
- O'Connor, Thomas;
- Hiromi Kudo;
- Mukherjee, K.;
- Wendon, Julia A.;
- Bernsmeier, Christine;
- Goldin, Robert D.;
- Botto, Marina;
- Khamri, Wafa;
- McPhai, Mark J. W.;
- Possamai, Lucia A.;
- Woollard, Kevin J.;
- Antoniades, Charalambos G.;
- Thursz, Mark R.;
- Kudo, Hiromi
Publication type:
journal article
Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice.
Published in:
2021
By:
- Kadiyala, Padma;
- Carney, Stephen V.;
- Gauss, Jessica C.;
- Garcia-Fabiani, Maria B.;
- Haase, Santiago;
- Alghamri, Mahmoud S.;
- Núñez, Felipe J.;
- Yayuan Liu;
- Minzhi Yu;
- Taher, Ayman;
- Nunez, Fernando M.;
- Dan Li;
- Edwards, Marta B.;
- Kleer, Celina G.;
- Appelman, Henry;
- Yilun Sun;
- Lili Zhao;
- Moon, James J.;
- Schwendeman, Anna;
- Lowenstein, Pedro R.
Publication type:
journal article
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer.
Published in:
2021
By:
- Edwards, Deanna N.;
- Ngwa, Verra M.;
- Raybuck, Ariel L.;
- Shan Wang;
- Yoonha Hwang;
- Kim, Laura C.;
- Sung Hoon Cho;
- Paik, Yeeun;
- Qingfei Wang;
- Siyuan Zhang;
- Manning, H. Charles;
- Rathmell, Jeffrey C.;
- Cook, Rebecca S.;
- Boothby, Mark R.;
- Jin Chen;
- Wang, Shan;
- Hwang, Yoonha;
- Cho, Sung Hoon;
- Wang, Qingfei;
- Zhang, Siyuan
Publication type:
journal article
Endothelium-derived semaphorin 3G attenuates ischemic retinopathy by coordinating β-catenin-dependent vascular remodeling.
Published in:
2021
By:
- Dan-Yang Chen;
- Ning-He Sun;
- Xiang Chen;
- Song-Tao Yuan;
- Zi-Zhong Hu;
- Nan-Nan Lu;
- Jakob Körbelin;
- Kohji Fukunaga;
- Qing-Huai Liu;
- Ying-Mei Lu;
- Feng Han;
- Chen, Dan-Yang;
- Sun, Ning-He;
- Chen, Xiang;
- Gong, Jun-Jie;
- Yuan, Song-Tao;
- Hu, Zi-Zhong;
- Lu, Nan-Nan;
- Körbelin, Jakob;
- Fukunaga, Kohji
Publication type:
journal article
TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis.
Published in:
2021
By:
- Jinchao Hou;
- Jue Zhang;
- Ping Cui;
- Yingyue Zhou;
- Can Liu;
- Xiaoliang Wu;
- Yun Ji;
- Sicong Wang;
- Baoli Cheng;
- Hui Ye;
- Liqi Shu;
- Kai Zhang;
- Di Wang;
- Jielin Xu;
- Qiang Shu;
- Colonna, Marco;
- Xiangming Fang;
- Hou, Jinchao;
- Zhang, Jue;
- Cui, Ping
Publication type:
journal article
Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer.
Published in:
Journal of Clinical Investigation, 2021, v. 131, n. 4, p. 1, doi. 10.1172/jci131517
By:
- Guo, Yuchen;
- Gabola, Monica;
- Lattanzio, Rossano;
- Paul, Conception;
- Pinet, Valérie;
- Ruizhi Tang;
- Tural, Hulya;
- Bremond, Julie;
- Longobardi, Ciro;
- Maurizy, Chloé;
- Da Costa, Quentin;
- Finetti, Pascal;
- Boissière-Michot, Florence;
- Rivière, Benjamin;
- Lemmers, Céline;
- Garnier, Séverine;
- Bertucci, François;
- Zlobec, Inti;
- Chebli, Karim;
- Tazi, Jamal
Publication type:
Article
Streptococcus pyogenes infects human endometrium by limiting the innate immune response.
Published in:
2021
By:
- Weckel, Antonin;
- Guilbert, Thomas;
- Lambert, Clara;
- Plainvert, Céline;
- Goffinet, François;
- Poyart, Claire;
- Méhate, Céline;
- Fouet, Agnès;
- Goffinet, Francois;
- Méhats, Céline
Publication type:
journal article
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Published in:
2021
By:
- Sandusky-Beltran, Leslie A.;
- Kovalenko, Andrii;
- Placides, Devon S.;
- Ratnasamy, Kevin;
- Chao Ma;
- Hunt Jr, Jerry B.;
- Liang, Huimin;
- Calahatian, John Ivan T.;
- Michalski, Camilla;
- Fahnestock, Margaret;
- Blair, Laura J.;
- Darling, April L.;
- Baker, Jeremy D.;
- Fontaine, Sarah N.;
- Dickey, Chad A.;
- Gamsby, Joshua J.;
- Nash, Kevin R.;
- Abner, Erin;
- Selenica, Maj-Linda B.;
- Lee, Daniel C.
Publication type:
journal article

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