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The next big LEAP2 understanding ghrelin function.
Published in:
2019
By:
- Andrews, Zane B.
Publication type:
journal article
Diving beneath the surface: addressing gender inequities among clinical investigators.
Published in:
2019
By:
- Beeler, Whitney H.;
- Cortina, Lilia M.;
- Jagsi, Reshma
Publication type:
journal article
A PHD in immunosuppression: oxygen-sensing pathways regulate immunosuppressive Tregs.
Published in:
2019
By:
- Weiping Zou;
- Shah, Yatrik M.;
- Zou, Weiping
Publication type:
journal article
Human fecal metabolomic profiling could inform Clostridioides difficile infection diagnosis and treatment.
Published in:
2019
By:
- Theriot, Casey M.;
- Fletcher, Joshua R.
Publication type:
journal article
The supply chain of human pancreatic β cell lines.
Published in:
2019
By:
- Scharfmann, Raphael;
- Staels, Willem;
- Albagli, Olivier
Publication type:
journal article
Clinical testing should be individualized, not based on populations.
Published in:
2019
By:
- Walt, David R.
Publication type:
journal article
The perils of intersectionality: racial and sexual harassment in medicine.
Published in:
2019
By:
- Golden, Sherita Hill
Publication type:
journal article
Oxidative stress and α-synuclein conspire in vulnerable neurons to promote Parkinson's disease progression.
Published in:
2019
By:
- Luk, Kelvin C.
Publication type:
journal article
Antiobesogenic effects of central GIPR antagonism.
Published in:
2019
By:
- Yue, Jessica T. Y.;
- Lam, Tony K. T.;
- Yue, Jessica Ty;
- Lam, Tony Kt
Publication type:
journal article
Hybrid lipids, peptides, and lymphocytes: new era in type 1 diabetes research.
Published in:
2019
By:
- Hamad, Abdel Rahim A.;
- Sadasivam, Mohanraj;
- Rabb, Hamid
Publication type:
journal article
Breaking barriers for T cells by targeting the EPHA2/TGF-β/COX-2 axis in pancreatic cancer.
Published in:
2019
By:
- Conejo-Garcia, Jose R.
Publication type:
journal article
Functional diversification of IgGs through Fc glycosylation.
Published in:
2019
By:
- Wang, Taia T.;
- Ravetch, Jeffrey V.
Publication type:
journal article
X-tra X: An escape to autoimmunity.
Published in:
2019
By:
- Wu, Gregory F.
Publication type:
journal article
Targeting innate immunity for tuberculosis vaccination.
Published in:
2019
By:
- Khader, Shabaana A.;
- Divangahi, Maziar;
- Hanekom, Willem;
- Hill, Philip C.;
- Maeurer, Markus;
- Makar, Karen W.;
- Mayer-Barber, Katrin D.;
- Mhlanga, Musa M.;
- Nemes, Elisa;
- Schlesinger, Larry S.;
- van Crevel, Reinout;
- Vankalayapati, Ramakrishna;
- Xavier, Ramnik J.;
- Netea, Mihai G.;
- Vankayalapati, Raman (Krishna);
- Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group18
Publication type:
journal article
Killers 2.0: NK cell therapies at the forefront of cancer control.
Published in:
2019
By:
- Hodgins, Jonathan J.;
- Khan, Sarwat T.;
- Park, Maria M.;
- Auer, Rebecca C.;
- Ardolino, Michele
Publication type:
journal article
Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2).
Published in:
2019
By:
- Markosyan, Nune;
- Jinyang Li;
- Sun, Yu H.;
- Richman, Lee P.;
- Lin, Jeffrey H.;
- Fangxue Yan;
- Quinones, Liz;
- Sela, Yogev;
- Taiji Yamazoe;
- Gordon, Naomi;
- Tobias, John W.;
- Byrne, Katelyn T.;
- Rech, Andrew J.;
- FitzGerald, Garret A.;
- Stanger, Ben Z.;
- Vonderheide, Robert H.;
- Li, Jinyang;
- Yan, Fangxue;
- Yamazoe, Taiji
Publication type:
journal article
TLR9 signaling in fibroblastic reticular cells regulates peritoneal immunity.
Published in:
2019
By:
- Li Xu;
- Yiming Li;
- Chenxuan Yang;
- Loughran, Patricia;
- Hong Liao;
- Hoffman, Rosemary;
- Billiar, Timothy R.;
- Meihong Deng;
- Xu, Li;
- Li, Yiming;
- Yang, Chenxuan;
- Liao, Hong;
- Deng, Meihong
Publication type:
journal article
Antibodies targeting sialyl Lewis A mediate tumor clearance through distinct effector pathways.
Published in:
2019
By:
- Weitzenfeld, Polina;
- Bournazos, Stylianos;
- Ravetch, Jeffrey V.
Publication type:
journal article
Allergen presensitization drives an eosinophil-dependent arrest in lung-specific helminth development.
Published in:
2019
By:
- Gazzinelli-Guimaraes, Pedro H.;
- de Queiroz Prado, Rafael;
- Ricciardi, Alessandra;
- Bonne-Année, Sandra;
- Sciurba, Joshua;
- Karmele, Erik P.;
- Fujiwara, Ricardo T.;
- Nutman, Thomas B.
Publication type:
journal article
N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
Published in:
Journal of Clinical Investigation, 2019, v. 129, n. 9, p. 3924, doi. 10.1172/JCI127961
By:
- Berger, Adeline;
- Brady, Nicholas J.;
- Bareja, Rohan;
- Robinson, Brian;
- Conteduca, Vincenza;
- Augello, Michael A.;
- Puca, Loredana;
- Ahmed, Adnan;
- Dardenne, Etienne;
- Xiaodong Lu;
- Inah Hwang;
- Bagadion, Alyssa M.;
- Sboner, Andrea;
- Elemento, Olivier;
- Paik, Jihye;
- Jindan Yu;
- Barbieri, Christopher E.;
- Dephoure, Noah;
- Beltran, Himisha;
- Rickman, David S.
Publication type:
Article
The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration.
Published in:
2019
By:
- Masaki Uchida;
- Maier, Bernhard;
- Waghwani, Hitesh Kumar;
- Selivanovitch, Ekaterina;
- Pay, S. Louise;
- Avera, John;
- EJun Yun;
- Sandoval, Ruben M.;
- Molitoris, Bruce A.;
- Zollman, Amy;
- Douglas, Trevor;
- Takashi Hato;
- Uchida, Masaki;
- Yun, EJun;
- Hato, Takashi
Publication type:
journal article
Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells.
Published in:
2019
By:
- Ningguo Feng;
- Liya Hu;
- Siyuan Ding;
- Sanyal, Mrinmoy;
- Boyang Zhao;
- Sankaran, Banumathi;
- Ramani, Sasirekha;
- McNeal, Monica;
- Yasukawa, Linda L.;
- Yanhua Song;
- Prasad, B. V. Venkataram;
- Greenberg, Harry B.;
- Feng, Ningguo;
- Hu, Liya;
- Ding, Siyuan;
- Zhao, Boyang;
- Song, Yanhua
Publication type:
journal article
Neuronal FcγRI mediates acute and chronic joint pain.
Published in:
2019
By:
- Li Wang;
- Xiaohua Jiang;
- Qin Zheng;
- Sang-Min Jeon;
- Tiane Chen;
- Yan Liu;
- Kulaga, Heather;
- Reed, Randall;
- Xinzhong Dong;
- J. Caterina, Michael;
- Lintao Qu;
- Wang, Li;
- Jiang, Xiaohua;
- Zheng, Qin;
- Jeon, Sang-Min;
- Chen, Tiane;
- Liu, Yan;
- Dong, Xinzhong;
- Caterina, Michael J;
- Qu, Lintao
Publication type:
journal article
Long telomeres and cancer risk: the price of cellular immortality.
Published in:
2019
By:
- McNally, Emily J.;
- Luncsford, Paz J.;
- Armanios, Mary
Publication type:
journal article
Metabolomic networks connect host-microbiome processes to human Clostridioides difficile infections.
Published in:
2019
By:
- Robinson, John I.;
- Weir, William H.;
- Crowley, Jan R.;
- Hink, Tiffany;
- Reske, Kimberly A.;
- Kwon, Jennie H.;
- Burnham, Carey-Ann D.;
- Dubberke, Erik R.;
- Mucha, Peter J.;
- Henderson, Jeffrey P.
Publication type:
journal article
TGFβ signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome.
Published in:
2019
By:
- Joyce, Cailin E.;
- Saadatpour, Assieh;
- Ruiz-Gutierrez, Melisa;
- Bolukbasi, Ozge Vargel;
- Lan Jiang;
- Thomas, Dolly D.;
- Young, Sarah;
- Hofmann, Inga;
- Sieff, Colin A.;
- Myers, Kasiani C.;
- Whangbo, Jennifer;
- Libermann, Towia A.;
- Nusbaum, Chad;
- Guo-Cheng Yuan;
- Shimamura, Akiko;
- Novina, Carl D.;
- Jiang, Lan;
- Yuan, Guo-Cheng
Publication type:
journal article
Oxidative stress in vagal neurons promotes parkinsonian pathology and intercellular α-synuclein transfer.
Published in:
2019
By:
- Musgrove, Ruth E.;
- Helwig, Michael;
- Eun-Jin Bae;
- Aboutalebi, Helia;
- Seung-Jae Lee;
- Ulusoy, Ayse;
- Di Monte, Donato A.;
- Bae, Eun-Jin;
- Lee, Seung-Jae
Publication type:
journal article
Multiple stimulation parameters influence efficacy of deep brain stimulation in parkinsonian mice.
Published in:
2019
By:
- Schor, Jonathan S.;
- Nelson, Alexandra B.
Publication type:
journal article
RASA1-dependent cellular export of collagen IV controls blood and lymphatic vascular development.
Published in:
2019
By:
- Di Chen;
- Teng, Joyce M.;
- North, Paula E.;
- Lapinski, Philip E.;
- King, Philip D.;
- Chen, Di
Publication type:
journal article
TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.
Published in:
2019
By:
- Kunihiko Araki;
- Amane Araki;
- Daiyu Honda;
- Takako Izumoto;
- Atsushi Hashizume;
- Yasuhiro Hijikata;
- Shinichiro Yamada;
- Yohei Iguchi;
- Akitoshi Hara;
- Kazuhiro Ikumi;
- Kaori Kawai;
- Shinsuke Ishigaki;
- Yoko Nakamichi;
- Shin Tsunekawa;
- Yusuke Seino;
- Akiko Yamamoto;
- Yasunori Takayama;
- Shihomi Hidaka;
- Makoto Tominaga;
- Mica Ohara-Imaizumi
Publication type:
journal article
Roles of HIFs and VEGF in angiogenesis in the retina and brain.
Published in:
2019
By:
- Rattner, Amir;
- Williams, John;
- Nathans, Jeremy
Publication type:
journal article
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.
Published in:
2019
By:
- Channappanavar, Rudragouda;
- Fehr, Anthony R.;
- Jian Zheng;
- Wohlford-Lenane, Christine;
- Abrahante, Juan E.;
- Mack, Matthias;
- Sompallae, Ramakrishna;
- McCray Jr., Paul B.;
- Meyerholz, David K.;
- Perlman, Stanley;
- Zheng, Jian;
- McCray, Paul B Jr
Publication type:
journal article
β-Cell-intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion.
Published in:
2019
By:
- Barella, Luiz F.;
- Rossi, Mario;
- Lu Zhu;
- Yinghong Cui;
- Mei, Fang C.;
- Xiaodong Cheng;
- Wei Chen;
- Gurevich, Vsevolod V.;
- Wess, Jürgen;
- Zhu, Lu;
- Cui, Yinghong;
- Cheng, Xiaodong;
- Chen, Wei
Publication type:
journal article
The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity.
Published in:
2019
By:
- Yuichiro Itoh;
- Golden, Lisa C.;
- Noriko Itoh;
- Macy Akiyo Matsukawa;
- Ren, Emily;
- Tse, Vincent;
- Arnold, Arthur P.;
- Voskuhl, Rhonda R.;
- Itoh, Yuichiro;
- Itoh, Noriko;
- Matsukawa, Macy Akiyo
Publication type:
journal article
Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.
Published in:
2019
By:
- Shigeki Sekine;
- Tohru Kiyono;
- Eijitsu Ryo;
- Reiko Ogawa;
- Susumu Wakai;
- Hitoshi Ichikawa;
- Koyu Suzuki;
- Satoru Arai;
- Koji Tsuta;
- Mitsuaki Ishida;
- Yuko Sasajima;
- Naoki Goshima;
- Naoya Yamazaki;
- Taisuke Mori;
- Sekine, Shigeki;
- Kiyono, Tohru;
- Ryo, Eijitsu;
- Ogawa, Reiko;
- Wakai, Susumu;
- Ichikawa, Hitoshi
Publication type:
journal article
Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition.
Published in:
2019
By:
- Kentaro Kaneko;
- Yukiko Fu;
- Hsiao-Yun Lin;
- Cordonier, Elizabeth L.;
- Qianxing Mo;
- Yong Gao;
- Ting Yao;
- Naylor, Jacqueline;
- Howard, Victor;
- Kenji Saito;
- Pingwen Xu;
- Chen, Siyu S.;
- Miao-Hsueh Chen;
- Yong Xu;
- Williams, Kevin W.;
- Ravn, Peter;
- Makoto Fukuda;
- Kaneko, Kentaro;
- Fu, Yukiko;
- Lin, Hsiao-Yun
Publication type:
journal article
CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells.
Published in:
2019
By:
- Halkias, Joanna;
- Rackaityte, Elze;
- Hillman, Sara L.;
- Aran, Dvir;
- Mendoza, Ventura F.;
- Marshall, Lucy R.;
- MacKenzie, Tippi C.;
- Burt, Trevor D.
Publication type:
journal article
Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming.
Published in:
2019
By:
- Merino, Aimee;
- Bin Zhang;
- Dougherty, Philip;
- Xianghua Luo;
- Jinhua Wang;
- Blazar, Bruce R.;
- Miller, Jeffrey S.;
- Cichocki, Frank;
- Zhang, Bin;
- Luo, Xianghua;
- Wang, Jinhua
Publication type:
journal article
Systemic silencing of PHD2 causes reversible immune regulatory dysfunction.
Published in:
2019
By:
- Atsushi Yamamoto;
- Hester, Joanna;
- Macklin, Philip S.;
- Kawai, Kento;
- Masateru Uchiyama;
- Biggs, Daniel;
- Bishop, Tammie;
- Bull, Katherine;
- Xiaotong Cheng;
- Cawthorne, Eleanor;
- Coleman, Mathew L.;
- Crockford, Tanya L.;
- Davies, Ben;
- Dow, Lukas E.;
- Goldin, Rob;
- Kranc, Kamil;
- Hiromi Kudo;
- Lawson, Hannah;
- McAuliffe, James;
- Milward, Kate
Publication type:
journal article
LEAP2 changes with body mass and food intake in humans and mice.
Published in:
2019
By:
- Mani, Bharath K.;
- Puzziferri, Nancy;
- Zhenyan He;
- Rodriguez, Juan A.;
- Osborne-Lawrence, Sherri;
- Metzger, Nathan P.;
- Chhina, Navpreet;
- Gaylinn, Bruce;
- Thorner, Michael O.;
- Thomas, E. Louise;
- Bell, Jimmy D.;
- Williams, Kevin W.;
- Goldstone, Anthony P.;
- Zigman, Jeffrey M.;
- He, Zhenyan
Publication type:
journal article
Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10-producing regulatory B cells.
Published in:
2019
By:
- Yoshiyuki Mishima;
- Akihiko Oka;
- Bo Liu;
- Herzog, Jeremy W.;
- Chang Soo Eun;
- Ting-Jia Fan;
- Bulik-Sullivan, Emily;
- Carroll, Ian M.;
- Hansen, Jonathan J.;
- Liang Chen;
- Wilson, Justin E.;
- Fisher, Nancy C.;
- Ting, Jenny P. Y.;
- Tomonori Nochi;
- Wahl, Angela;
- Garcia, J. Victor;
- Karp, Christopher L.;
- Sartor, R. Balfour;
- Mishima, Yoshiyuki;
- Oka, Akihiko
Publication type:
journal article
Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.
Published in:
2019
By:
- Chie Miyabe;
- Yoshishige Miyabe;
- Bricio-Moreno, Laura;
- Lian, Jeffrey;
- Rahimi, Rod A.;
- Miura, Noriko N.;
- Naohito Ohno;
- Yoichiro Iwakura;
- Tamihiro Kawakami;
- Luster, Andrew D.;
- Miyabe, Chie;
- Miyabe, Yoshishige;
- Ohno, Naohito;
- Iwakura, Yoichiro;
- Kawakami, Tamihiro
Publication type:
journal article
Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells.
Published in:
2019
By:
- Martin, Matthew D.;
- Jensen, Isaac J.;
- Ishizuka, Andrew S.;
- Lefebvre, Mitchell;
- Qiang Shan;
- Hai-Hui Xue;
- Harty, John T.;
- Seder, Robert A.;
- Badovinac, Vladimir P.;
- Shan, Qiang;
- Xue, Hai-Hui
Publication type:
journal article
Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model.
Published in:
2019
By:
- Meriwether, David;
- Sulaiman, Dawoud;
- Volpe, Carmen;
- Dorfman, Anna;
- Grijalva, Victor;
- Dorreh, Nasrin;
- Solorzano-Vargas, R. Sergio;
- Jifang Wang;
- O’Connor, Ellen;
- Papesh, Jeremy;
- Larauche, Muriel;
- Trost, Hannah;
- Palgunachari, Mayakonda N.;
- Anantharamaiah, G. M.;
- Herschman, Harvey R.;
- Martin, Martin G.;
- Fogelman, Alan M.;
- Reddy, Srinivasa T.;
- Wang, Jifang;
- O'Connor, Ellen
Publication type:
journal article
Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.
Published in:
2019
By:
- Jia He;
- Yinjing Song;
- Gaopeng Li;
- Peng Xiao;
- Yang Liu;
- Yue Xue;
- Qian Cao;
- Xintao Tu;
- Ting Pan;
- Zhinong Jiang;
- Xuetao Cao;
- Lihua Lai;
- Qingqing Wang;
- He, Jia;
- Song, Yinjing;
- Li, Gaopeng;
- Xiao, Peng;
- Liu, Yang;
- Xue, Yue;
- Cao, Qian
Publication type:
journal article
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Published in:
2019
By:
- Haiqing Zhang;
- Xin Tian;
- Xi Lu;
- Demei Xu;
- Yi Guo;
- Zhifang Dong;
- Yun Li;
- Yuanlin Ma;
- Chengzhi Chen;
- Yong Yang;
- Min Yang;
- Yi Yang;
- Feng Liu;
- Ruijiao Zhou;
- Miaoqing He;
- Fei Xiao;
- Xuefeng Wang;
- Zhang, Haiqing;
- Tian, Xin;
- Lu, Xi
Publication type:
journal article
PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice.
Published in:
2019
By:
- Syed, Ismail;
- Rubin de Celis, Maria F.;
- Mohan, James F.;
- Moraes-Vieira, Pedro M.;
- Vijayakumar, Archana;
- Nelson, Andrew T.;
- Siegel, Dionicio;
- Saghatelian, Alan;
- Mathis, Diane;
- Kahn, Barbara B.
Publication type:
journal article

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