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Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates.
Published in:
2018
By:
- Gu, Xiaorong;
- Ebrahem, Quteba;
- Mahfouz, Reda Z;
- Hasipek, Metis;
- Enane, Francis;
- Radivoyevitch, Tomas;
- Rapin, Nicolas;
- Przychodzen, Bartlomiej;
- Hu, Zhenbo;
- Balusu, Ramesh;
- Cotta, Claudiu V;
- Wald, David;
- Argueta, Christian;
- Landesman, Yosef;
- Martelli, Maria Paola;
- Falini, Brunangelo;
- Carraway, Hetty;
- Porse, Bo T;
- Maciejewski, Jaroslaw;
- Jha, Babal K
Publication type:
journal article
Generations of physician-scientists.
Published in:
2018
By:
- Ebert, Benjamin L.
Publication type:
journal article
RNA biologist Joan Steitz awarded the 2018 Lasker~Koshland Special Achievement prize.
Published in:
2018
By:
- Jackson, Sarah
Publication type:
Biography
Aging and scientific medicine: 60 is the new 40.
Published in:
2018
By:
- Erzurum, Serpil C.
Publication type:
journal article
Michael Grunstein and David Allis receive the 2018 Lasker Basic Medical Research Award.
Published in:
2018
By:
- Williams, Corinne L.
Publication type:
historical material
Science, serendipity, and the single degree.
Published in:
2018
By:
- Hobbs, Helen H.
Publication type:
journal article
The 2018 Lasker~DeBakey Clinical Medical Research Award recognizes John Baird Glen for the discovery of propofol.
Published in:
2018
By:
- Dankoski, Elyse
Publication type:
Biography
Entering the spotlight: hepatitis B surface antigen-specific B cells.
Published in:
2018
By:
- Neumann-Haefelin, Christoph;
- Thimme, Robert
Publication type:
journal article
Stu Orkin is a superhero.
Published in:
2018
By:
- Zon, Leonard I.
Publication type:
journal article
A conversation with Carla Shatz.
Published in:
2018
By:
- Neill, Ushma S
Publication type:
Biography
Making the scientific literature fail-safe.
Published in:
2018
By:
- Casadevall, Arturo;
- Fang, Ferric C.
Publication type:
journal article
Neutralize the neutrophils! Neutrophil β1/β2 integrin activation contributes to JAK2-V617F-driven thrombosis.
Published in:
2018
By:
- Oh, Stephen T.
Publication type:
journal article
Targeting the aryl hydrocarbon receptor/polyamine biosynthesis axis of evil for cancer therapy.
Published in:
2018
By:
- Casero Jr., Robert A.;
- Casero, Robert A Jr
Publication type:
journal article
Tale of two vaccines: differences in response to herpes zoster vaccines.
Published in:
2018
By:
- Gershon, Anne A.
Publication type:
journal article
NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell.
Published in:
2018
By:
- Dunai, Cordelia;
- Murphy, William J.
Publication type:
journal article
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
Published in:
2018
By:
- McKenney, Anna Sophia;
- Lau, Allison N;
- Somasundara, Amritha Varshini Hanasoge;
- Spitzer, Barbara;
- Intlekofer, Andrew M;
- Ahn, Jihae;
- Shank, Kaitlyn;
- Rapaport, Franck T;
- Patel, Minal A;
- Papalexi, Efthymia;
- Shih, Alan H;
- Chiu, April;
- Freinkman, Elizaveta;
- Akbay, Esra A;
- Steadman, Mya;
- Nagaraja, Raj;
- Yen, Katharine;
- Teruya-Feldstein, Julie;
- Wong, Kwok-Kin;
- Rampal, Raajit
Publication type:
journal article
Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
Published in:
2018
By:
- Jin, Cong;
- Shelburne, Christopher P;
- Li, Guojie;
- Potts, Erin N;
- Riebe, Kristina J;
- Sempowski, Gregory D;
- Foster, W Michael;
- Abraham, Soman N
Publication type:
journal article
Regulatory T cells in embryo implantation and the immune response to pregnancy.
Published in:
2018
By:
- Robertson, Sarah A.;
- Care, Alison S.;
- Moldenhauer, Lachlan M.
Publication type:
journal article
DNA repair defects and implications for immunotherapy.
Published in:
2018
By:
- Bever, Katherine M.;
- Le, Dung T.
Publication type:
journal article
ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
Published in:
2018
By:
- Liles, John T.;
- Corkey, Britton K.;
- Notte, Gregory T.;
- Budas, Grant R.;
- Lansdon, Eric B.;
- Hinojosa-Kirschenbaum, Ford;
- Badal, Shawn S.;
- Lee, Michael;
- Schultz, Brian E.;
- Wise, Sarah;
- Pendem, Swetha;
- Graupe, Michael;
- Castonguay, Laurie;
- Koch, Keith A.;
- Wong, Melanie H.;
- Papalia, Giuseppe A.;
- French, Dorothy M.;
- Sullivan, Theodore;
- Huntzicker, Erik G.;
- Ma, Frank Y.
Publication type:
journal article
Use of contraceptive depot medroxyprogesterone acetate is associated with impaired cervicovaginal mucosal integrity.
Published in:
2018
By:
- Zalenskaya, Irina A.;
- Chandra, Neelima;
- Yousefieh, Nazita;
- Xi Fang;
- Adedipe, Oluwatosin E.;
- Jackson, Suzanne S.;
- Anderson, Sharon M.;
- Mauck, Christine K.;
- Schwartz, Jill L.;
- Thurman, Andrea R.;
- Doncel, Gustavo F.;
- Fang, Xi
Publication type:
journal article
Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis.
Published in:
2018
By:
- Dongxue Su;
- Shuai Ma;
- Lin Shan;
- Yue Wang;
- Yuejiao Wang;
- Cheng Cao;
- Beibei Liu;
- Chao Yang;
- Liyong Wang;
- Shanshan Tian;
- Xiang Ding;
- Xinhua Liu;
- Na Yu;
- Nan Song;
- Ling Liu;
- Shangda Yang;
- Qi Zhang;
- Fuquan Yang;
- Kai Zhang;
- Lei Shi
Publication type:
journal article
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
Published in:
2018
By:
- Li Li;
- Naidu Guturi, Kiran Kumar;
- Gautreau, Brandon;
- Patel, Parasvi S.;
- Saad, Amine;
- Morii, Mayako;
- Mateo, Francesca;
- Palomero, Luis;
- Barbour, Haithem;
- Gomez, Antonio;
- Deborah Ng;
- Kotlyar, Max;
- Pastrello, Chiara;
- Jackson, Hartland W.;
- Khokha, Rama;
- Jurisica, Igor;
- Affar, El Bachir;
- Raught, Brian;
- Sanchez, Otto;
- Alaoui-Jamali, Moulay
Publication type:
journal article
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
Published in:
2018
By:
- Burton, Alice R.;
- Pallett, Laura J.;
- McCoy, Laura E.;
- Suveizdyte, Kornelija;
- Amin, Oliver E.;
- Swadling, Leo;
- Alberts, Elena;
- Davidson, Brian R.;
- Kennedy, Patrick T. F.;
- Gill, Upkar S.;
- Mauri, Claudia;
- Blair, Paul A.;
- Pelletier, Nadege;
- Maini, Mala K.;
- Kennedy, Patrick Tf
Publication type:
journal article
PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection.
Published in:
2018
By:
- Salimzadeh, Loghman;
- Le Bert, Nina;
- Dutertre, Charles-A.;
- Gill, Upkar S.;
- Newell, Evan W.;
- Frey, Christian;
- Hung, Magdeleine;
- Novikov, Nikolai;
- Fletcher, Simon;
- Kennedy, Patrick T. F.;
- Bertoletti, Antonio;
- Kennedy, Patrick Tf
Publication type:
journal article
Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.
Published in:
2018
By:
- Rodrigues, Daniel Nava;
- Rescigno, Pasquale;
- Liu, David;
- Wei Yuan;
- Carreira, Suzanne;
- Lambros, Maryou B.;
- Seed, George;
- Mateo, Joaquin;
- Riisnaes, Ruth;
- Mullane, Stephanie;
- Margolis, Claire;
- Miao, Diana;
- Miranda, Susana;
- Dolling, David;
- Clarke, Matthew;
- Bertan, Claudia;
- Crespo, Mateus;
- Boysen, Gunther;
- Ferreira, Ana;
- Sharp, Adam
Publication type:
journal article
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium.
Published in:
2018
By:
- Dar, Haider H.;
- Tyurina, Yulia Y.;
- Mikulska-Ruminska, Karolina;
- Shrivastava, Indira;
- Hsiu-Chi Ting;
- Tyurin, Vladimir A.;
- Krieger, James;
- St. Croix, Claudette M.;
- Watkins, Simon;
- Bayir, Erkan;
- Mao, Gaowei;
- Armbruster, Catherine R.;
- Kapralov, Alexandr;
- Hong Wang;
- Parsek, Matthew R.;
- Anthonymuthu, Tamil S.;
- Ogunsola, Abiola F.;
- Flitter, Becca A.;
- Freedman, Cody J.;
- Gaston, Jordan R.
Publication type:
journal article
Zika virus infects human testicular tissue and germ cells.
Published in:
2018
By:
- Matusali, Giulia;
- Houzet, Laurent;
- Satie, Anne-Pascale;
- Mahé, Dominique;
- Aubry, Florence;
- Couderc, Thérèse;
- Frouard, Julie;
- Bourgeau, Salomé;
- Bensalah, Karim;
- Lavoué, Sylvain;
- Joguet, Guillaume;
- Bujan, Louis;
- Cabié, André;
- Avelar, Gleide;
- Lecuit, Marc;
- Le Tortorec, Anna;
- Dejucq-Rainsford, Nathalie
Publication type:
journal article
No recovery of replication-competent HIV-1 from human liver macrophages.
Published in:
2018
By:
- Kandathil, Abraham J.;
- Sugawara, Sho;
- Goyal, Ashish;
- Durand, Christine M.;
- Quinn, Jeffrey;
- Sachithanandham, Jaiprasath;
- Cameron, Andrew M.;
- Bailey, Justin R.;
- Perelson, Alan S.;
- Balagopal, Ashwin
Publication type:
journal article
Th1 memory differentiates recombinant from live herpes zoster vaccines.
Published in:
2018
By:
- Levin, Myron J.;
- Kroehl, Miranda E.;
- Johnson, Michael J.;
- Hammes, Andrew;
- Reinhold, Dominik;
- Lang, Nancy;
- Weinberg, Adriana
Publication type:
journal article
Endothelial pyruvate kinase M2 maintains vascular integrity.
Published in:
2018
By:
- Boa Kim;
- Cholsoon Jang;
- Dharaneeswaran, Harita;
- Jian Li;
- Bhide, Mohit;
- Yang, Steven;
- Li, Kristina;
- Arany, Zolt;
- Kim, Boa;
- Jang, Cholsoon;
- Li, Jian
Publication type:
journal article
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer.
Published in:
2018
By:
- Mabe, Nathaniel W.;
- Fox, Douglas B.;
- Lupo, Ryan;
- Decker, Amy E.;
- Phelps, Stephanie N.;
- Thompson, J. Will;
- Alvarez, James V.
Publication type:
journal article
Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth.
Published in:
2018
By:
- Fontán, Lorena;
- Qi Qiao;
- Hatcher, John M.;
- Casalena, Gabriella;
- Us, Ilkay;
- Teater, Matt;
- Durant, Matt;
- Guangyan Du;
- Min Xia;
- Bilchuk, Natalia;
- Chennamadhavuni, Spandan;
- Palladino, Giuseppe;
- Inghirami, Giorgio;
- Philippar, Ulrike;
- Hao Wu;
- Scott, David A.;
- Gray, Nathanael S.;
- Melnick, Ari;
- Qiao, Qi;
- Du, Guangyan
Publication type:
journal article
Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype.
Published in:
2018
By:
- Chaoqun Wang;
- Reyes de Mochel, Nabora S.;
- Christenson, Stephanie A.;
- Cassandras, Monica;
- Moon, Rebecca;
- Brumwell, Alexis N.;
- Byrnes, Lauren E.;
- Li, Alfred;
- Yasuyuki Yokosaki;
- Peiying Shan;
- Sneddon, Julie B.;
- Jablons, David;
- Lee, Patty J.;
- Matthay, Michael A.;
- Chapman, Harold A.;
- Tien Peng;
- Wang, Chaoqun;
- de Mochel, Nabora S Reyes;
- Yokosaki, Yasuyuki;
- Shan, Peiying
Publication type:
journal article
Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming.
Published in:
2018
By:
- Mishra, Rajeev;
- Haldar, Subhash;
- Placencio, Veronica;
- Madhav, Anisha;
- Rohena-Rivera, Krizia;
- Agarwal, Priyanka;
- Duong, Frank;
- Angara, Bryan;
- Tripathi, Manisha;
- Zhenqiu Liu;
- Gottlieb, Roberta A.;
- Wagner, Shawn;
- Posadas, Edwin M.;
- Bhowmick, Neil A.;
- Liu, Zhenqiu
Publication type:
journal article
Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade.
Published in:
2018
By:
- Hsu, Joy;
- Hodgins, Jonathan J.;
- Marathe, Malvika;
- Nicolai, Chris J.;
- Bourgeois-Daigneault, Marie-Claude;
- Trevino, Troy N.;
- Azimi, Camillia S.;
- Scheer, Amit K.;
- Randolph, Haley E.;
- Thompson, Thornton W.;
- Zhang, Lily;
- Iannello, Alexandre;
- Mathur, Nikhita;
- Jardine, Karen E.;
- Kirn, Georgia A.;
- Bell, John C.;
- McBurney, Michael W.;
- Raulet, David H.;
- Ardolino, Michele
Publication type:
journal article
Endothelial cell CD36 optimizes tissue fatty acid uptake.
Published in:
2018
By:
- Ni-Huiping Son;
- Basu, Debapriya;
- Samovski, Dmitri;
- Pietka, Terri A.;
- Peche, Vivek S.;
- Willecke, Florian;
- Xiang Fang;
- Shui-Qing Yu;
- Scerbo, Diego;
- Hye Rim Chang;
- Fei Sun;
- Bagdasarov, Svetlana;
- Drosatos, Konstantinos;
- Yeh, Steve T.;
- Mullick, Adam E.;
- Shoghi, Kooresh I.;
- Gumaste, Namrata;
- Kyeong Jin Kim;
- Huggins, Lesley-Ann;
- Lhakhang, Tenzin
Publication type:
journal article
Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment.
Published in:
2018
By:
- Allard, Denise E.;
- Yan Wang;
- Jian Joel Li;
- Conley, Bridget;
- Xu, Erin W.;
- Sailer, David;
- Kimpston, Caellaigh;
- Notini, Rebecca;
- Smith, Collin-Jamal;
- Koseoglu, Emel;
- Starmer, Joshua;
- Zeng, Xiaopei L.;
- Howard Jr, James F.;
- Hoke, Ahmet;
- Scherer, Steven S.;
- Su, Maureen A.;
- Wang, Yan;
- Li, Jian Joel;
- Howard, James F Jr
Publication type:
journal article
TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.
Published in:
2018
By:
- Liang Cheng;
- Qi Wang;
- Guangming Li;
- Banga, Riddhima;
- Jianping Ma;
- Haisheng Yu;
- Fumihiko Yasui;
- Zheng Zhang;
- Pantaleo, Giuseppe;
- Perreau, Matthieu;
- Zurawski, Sandra;
- Zurawski, Gerard;
- Levy, Yves;
- Lishan Su;
- Cheng, Liang;
- Wang, Qi;
- Li, Guangming;
- Ma, Jianping;
- Yu, Haisheng;
- Yasui, Fumihiko
Publication type:
journal article
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
Published in:
2018
By:
- Braun, Daniela A.;
- Lovric, Svjetlana;
- Schapiro, David;
- Schneider, Ronen;
- Marquez, Jonathan;
- Asif, Maria;
- Hussain, Muhammad Sajid;
- Daga, Ankana;
- Widmeier, Eugen;
- Rao, Jia;
- Ashraf, Shazia;
- Tan, Weizhen;
- Lusk, C. Patrick;
- Kolb, Amy;
- Jobst-Schwan, Tilman;
- Schmidt, Johanna Magdalena;
- Hoogstraten, Charlotte A.;
- Eddy, Kaitlyn;
- Kitzler, Thomas M.;
- Shril, Shirlee
Publication type:
journal article
Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferation.
Published in:
2018
By:
- Yaoyao Zou;
- Siqi Xu;
- Youjun Xiao;
- Qian Qiu;
- Maohua Shi;
- Jingnan Wang;
- Liuqin Liang;
- Zhongping Zhan;
- Xiuyan Yang;
- Nancy Olsen;
- Song Guo Zheng;
- Hanshi Xu;
- Zou, Yaoyao;
- Xu, Siqi;
- Xiao, Youjun;
- Qiu, Qian;
- Shi, Maohua;
- Wang, Jingnan;
- Liang, Liuqin;
- Zhan, Zhongping
Publication type:
journal article
Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans.
Published in:
2018
By:
- Ulrichts, Peter;
- Guglietta, Antonio;
- Dreier, Torsten;
- van Bragt, Tonke;
- Hanssens, Valérie;
- Hofman, Erik;
- Vankerckhoven, Bernhardt;
- Verheesen, Peter;
- Ongenae, Nicolas;
- Lykhopiy, Valentina;
- Enriquez, Javier;
- Jun Haeng Cho;
- Ober, Raimund J.;
- Ward, E. Sally;
- de Haard, Hans;
- Leupin, Nicolas;
- Enriquez, F Javier;
- Cho, JunHaeng
Publication type:
journal article
Inhibition of neogenin fosters resolution of inflammation and tissue regeneration.
Published in:
2018
By:
- Schlegel, Martin;
- Körner, Andreas;
- Kaussen, Torsten;
- Knausberg, Urs;
- Gerber, Carmen;
- Hansmann, Georg;
- Jónasdóttir, Hulda Soffia;
- Giera, Martin;
- Mirakaj, Valbona
Publication type:
journal article
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology.
Published in:
2018
By:
- Rangasamy, Suresh B.;
- Jana, Malabendu;
- Roy, Avik;
- Corbett, Grant T.;
- Kundu, Madhuchhanda;
- Chandra, Sujyoti;
- Mondal, Susanta;
- Dasarathi, Sridevi;
- Mufson, Elliott J.;
- Mishra, Rama K.;
- Chi-Hao Luan;
- Bennett, David A.;
- Pahan, Kalipada;
- Luan, Chi-Hao
Publication type:
journal article
REVERBa couples the circadian clock to hepatic glucocorticoid action.
Published in:
2018
By:
- Caratti, Giorgio;
- Iqbal, Mudassar;
- Hunter, Louise;
- Kim, Donghwan;
- Ping Wang;
- Vonslow, Ryan M.;
- Begley, Nicola;
- Tetley, Abigail J.;
- Woodburn, Joanna L.;
- Pariollaud, Marie;
- Maidstone, Robert;
- Donaldson, Ian J.;
- Zhenguang Zhang;
- Ince, Louise M.;
- Kitchen, Gareth;
- Baxter, Matthew;
- Poolman, Toryn M.;
- Daniels, Dion A.;
- Stirling, David R.;
- Brocker, Chad
Publication type:
journal article
PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.
Published in:
2018
By:
- Petrelli, Alessandra;
- Mijnheer, Gerdien;
- Hoytema van Konijnenburg, David P.;
- van der Wal, Maria M.;
- Giovannone, Barbara;
- Mocholi, Enric;
- Vazirpanah, Nadia;
- Broen, Jasper C.;
- Hijnen, Dirkjan;
- Oldenburg, Bas;
- Coffer, Paul J.;
- Vastert, Sebastian J.;
- Prakken, Berent J.;
- Spierings, Eric;
- Pandit, Aridaman;
- Mokry, Michal;
- van Wijk, Femke;
- van Konijnenburg, David P Hoytema
Publication type:
journal article
The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease.
Published in:
2018
By:
- McDonald-Hyman, Cameron;
- Muller, James T.;
- Loschi, Michael;
- Thangavelu, Govindarajan;
- Saha, Asim;
- Kumari, Sudha;
- Reichenbach, Dawn K.;
- Smith, Michelle J.;
- Guoan Zhang;
- Koehn, Brent H.;
- Jiqiang Lin;
- Mitchell, Jason S.;
- Fife, Brian T.;
- Panoskaltsis-Mortari, Angela;
- Feser, Colby J.;
- Kirchmeier, Andrew Kemal;
- Osborn, Mark J.;
- Hippen, Keli L.;
- Kelekar, Ameeta;
- Serody, Jonathan S.
Publication type:
journal article
JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
Published in:
2018
By:
- Edelmann, Bärbel;
- Gupta, Nibedita;
- Schnoeder, Tina M.;
- Oelschlegel, Anja M.;
- Shahzad, Khurrum;
- Goldschmidt, Jürgen;
- Philipsen, Lars;
- Weinert, Soenke;
- Ghosh, Aniket;
- Saalfeld, Felix C.;
- Nimmagadda, Subbaiah Chary;
- Müller, Peter;
- Braun-Dullaeus, Rüdiger;
- Mohr, Juliane;
- Wolleschak, Denise;
- Kliche, Stefanie;
- Amthauer, Holger;
- Heidel, Florian H.;
- Schraven, Burkhart;
- Isermann, Berend
Publication type:
journal article
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Published in:
2018
By:
- Bianchi-Smiraglia, Anna;
- Bagati, Archis;
- Fink, Emily E.;
- Affronti, Hayley C.;
- Lipchick, Brittany C.;
- Moparthy, Sudha;
- Long, Mark D.;
- Rosario, Spencer R.;
- Lightman, Shivana M.;
- Moparthy, Kalyana;
- Wolff, David W.;
- Dong Hyun Yun;
- Zhannan Han;
- Polechetti, Anthony;
- Roll, Matthew V.;
- Gitlin, Ilya I.;
- Leonova, Katerina I.;
- Rowsam, Aryn M.;
- Kandel, Eugene S.;
- Gudkov, Andrei V.
Publication type:
journal article
CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection.
Published in:
2018
By:
- Mathews, David V.;
- Ying Dong;
- Higginbotham, Laura B.;
- Kim, Steven C.;
- Breeden, Cynthia P.;
- Stobert, Elizabeth A.;
- Jenkins, Joseph;
- Yun Tso;
- Larsen, Christian P.;
- Adams, Andrew B.;
- Dong, Ying;
- Tso, J Yun
Publication type:
journal article

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