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Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.
Published in:
2015
By:
- Maltecca, Francesca;
- Baseggio, Elisa;
- Consolato, Francesco;
- Mazza, Davide;
- Podini, Paola;
- Young, Samuel M Jr;
- Drago, Ilaria;
- Bahr, Ben A;
- Puliti, Aldamaria;
- Codazzi, Franca;
- Quattrini, Angelo;
- Casari, Giorgio
Publication type:
journal article
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Published in:
2015
By:
- Gerriets, Valerie A;
- Kishton, Rigel J;
- Nichols, Amanda G;
- Macintyre, Andrew N;
- Inoue, Makoto;
- Ilkayeva, Olga;
- Winter, Peter S;
- Liu, Xiaojing;
- Priyadharshini, Bhavana;
- Slawinska, Marta E;
- Haeberli, Lea;
- Huck, Catherine;
- Turka, Laurence A;
- Wood, Kris C;
- Hale, Laura P;
- Smith, Paul A;
- Schneider, Martin A;
- MacIver, Nancie J;
- Locasale, Jason W;
- Newgard, Christopher B
Publication type:
journal article
Podoplanin negatively regulates CD4+ effector T cell responses.
Published in:
2015
By:
- Peters, Anneli;
- Burkett, Patrick R;
- Sobel, Raymond A;
- Buckley, Christopher D;
- Watson, Steve P;
- Bettelli, Estelle;
- Kuchroo, Vijay K
Publication type:
journal article
Corrigendum.
Published in:
2015
Publication type:
Correction Notice
Corrigendum.
Published in:
2015
Publication type:
Correction Notice
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.
Published in:
2015
By:
- Haller, Michael J.;
- Gitelman, Stephen E.;
- Gottlieb, Peter A.;
- Michels, Aaron W.;
- Rosenthal, Stephen M.;
- Shuster, Jonathan J.;
- Zou, Baiming;
- Brusko, Todd M.;
- Hulme, Maigan A.;
- Wasserfall, Clive H.;
- Mathews, Clayton E.;
- Atkinson, Mark A.;
- Schatz, Desmond A.
Publication type:
journal article
Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 437, doi. 10.1172/JCI78794
By:
- Bailey, Justin R.;
- Wasilewski, Lisa N.;
- Snider, Anna E.;
- El-Diwany, Ramy;
- Osburn, William O.;
- Zhenyong Keck;
- Foung, Steven K. H.;
- Ray, Stuart C.
Publication type:
Article
TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 425, doi. 10.1172/JCI78206
By:
- Zheng Hu;
- Wencheng Ding;
- Da Zhu;
- Lan Yu;
- Xiaohui Jiang;
- Xiaoli Wang;
- Changlin Zhang;
- Liming Wang;
- Teng Ji;
- Dan Liu;
- Dan He;
- Xi Xia;
- Tao Zhu;
- Juncheng Wei;
- Peng Wu;
- Changyu Wang;
- Ling Xi;
- Qinglei Gao;
- Gang Chen;
- Rong Liu
Publication type:
Article
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 413, doi. 10.1172/JCI78001
By:
- Gunther, Claudia;
- Kind, Barbara;
- Reijns, Martin A. M.;
- Berndt, Nicole;
- Martinez-Bueno, Manuel;
- Wolf, Christine;
- Tüngler, Victoria;
- Chara, Osvaldo;
- Young Ae Lee;
- Hübner, Norbert;
- Bicknell, Louise;
- Blum, Sophia;
- Krug, Claudia;
- Schmidt, Franziska;
- Kretschmer, Stefanie;
- Koss, Sarah;
- Astell, Katy R.;
- Ramantani, Georgia;
- Bauerfeind, Anja;
- Morris, David L.
Publication type:
Article
Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 263, doi. 10.1172/JCI74770
By:
- Maltecca, Franceca;
- Baseggio, Elisa;
- Consolato, Francesco;
- Mazza, Davide;
- Podini, Paola;
- Young Jr., Samuel M.;
- Drago, Ilaria;
- Bahr, Ben A.;
- Puliti, Aldamaria;
- Codazzi, Franca;
- Quattrini, Angelo;
- Casari, Giorgio
Publication type:
Article
Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 403, doi. 10.1172/JCI76919
By:
- Park, David S.;
- Cerrone, Marina;
- Morley, Gregory;
- Vasquez, Carolina;
- Fowler, Steven;
- Nian Liu;
- Bernstein, Scott A.;
- Fang-Yu Liu;
- Jie Zhang;
- Rogers, Christopher S.;
- Priori, Silvia G.;
- Chinitz, Larry A.;
- Fishman, Glenn I.
Publication type:
Article
Targeting development of incretin-producing cells increases insulin secretion.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 379, doi. 10.1172/JCI75838
By:
- Petersen, Natalia;
- Reimann, Frank;
- van Es, Johan H.;
- van den Berg, Bernard M.;
- Kroone, Chantal;
- Pais, Ramona;
- Jansen, Erik;
- Clevers, Hans;
- Gribble, Fiona M.;
- de Koning, Eelco J. P.
Publication type:
Article
Glucokinase activity in the arcuate nucleus regulates glucose intake.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 337, doi. 10.1172/JCI77172
By:
- Hussain, Syed;
- Richardson, Errol;
- Yue Ma;
- Holton, Christopher;
- De Backer, Ivan;
- Buckley, Niki;
- Dhillo, Waljit;
- Bewick, Gavin;
- Shuai Zhang;
- Carling, David;
- Bloom, Steve;
- Gardiner, James
Publication type:
Article
Follicular helper T cell signature in type 1 diabetes.
Published in:
2015
By:
- Kenefeck, Rupert;
- Chun Jing Wang;
- Kapadi, Tauseef;
- Wardzinski, Lukasz;
- Attridge, Kesley;
- Clough, Louise E.;
- Heuts, Frank;
- Kogimtzis, Alexandras;
- Patel, Sapna;
- Rosenthal, Miranda;
- Masahiro Ono;
- Sansom, David M.;
- Narendran, Parth;
- Walker, Lucy S. K.;
- Wang, Chun Jing;
- Kogimtzis, Alexandros;
- Ono, Masahiro
Publication type:
journal article
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 386, doi. 10.1172/JCI76738
By:
- Changtao Jiang;
- Cen Xie;
- Fei Li;
- Limin Zhang;
- Nichols, Robert C.;
- Krausz, Kristopher W.;
- Jingwei Cai;
- Yunpeng Qi;
- Zhong-Ze Fang;
- Shogo Takahashi;
- Naoki Tanaka;
- Desai, Dhimant;
- Amin, Shantu C.;
- Albert, Istvan;
- Patterson, Andrew D.;
- Gonzalez, Frank J.
Publication type:
Article
CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 365, doi. 10.1172/JCI66771
By:
- Krauthausen, Marius;
- Kummer, Markus P.;
- Zimmermann, Julian;
- Reyes-Irisarri, Elisabet;
- Terwel, Dick;
- Bulic, Bruno;
- Heneka, Michael T.;
- Müller, Marcus
Publication type:
Article
LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 304, doi. 10.1172/JCI76357
By:
- Shi-Dong Ma;
- Xuequn Xu;
- Plowshay, Julie;
- Ranheim, Erik A.;
- Burlingham, William J.;
- Jensen, Jeffrey L.;
- Asimakopoulos, Fotis;
- Weihua Tang;
- Gulley, Margaret L.;
- Cesarman, Ethel;
- Cumperz, Jenny E.;
- Kenney, Shannon C.
Publication type:
Article
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 275, doi. 10.1172/JCI74961
By:
- Hiroko Miyadera;
- Jun Ohashi;
- Lernmark, Åke;
- Toshio Kitamura;
- Katsushi Tokunaga
Publication type:
Article
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 350, doi. 10.1172/JCI77487
By:
- Johansson, Jenny U.;
- Woodling, Nathaniel S.;
- Qian Wang;
- Panchal, Maharshi;
- Xibin Liang;
- Trueba-Saiz, Angel;
- Brown, Holden D.;
- Mhatre, Siddhita D.;
- Loui, Taylor;
- Andreasson, Katrin I.
Publication type:
Article
Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 316, doi. 10.1172/JCI76802
By:
- Preuss, Klaus-Dieter;
- Pfreundschuh, Michael;
- Fadle, Natalie;
- Regitz, Evi;
- Kubuschok, Boris
Publication type:
Article
Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 324, doi. 10.1172/JCI76881
By:
- Zhongwen Xie;
- Wen Su;
- Shu Liu;
- Guogang Zhao;
- Esser, Karyn;
- Schroder, Elizabeth A.;
- Lefta, Mellani;
- Stauss, Harald M.;
- Zhenheng Guo;
- Ming Cui Gong
Publication type:
Article
Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 258, doi. 10.1172/jci78473
By:
- AlAsiri, Saleh;
- Basit, Sulman;
- Wood-Trageser, Michelle A.;
- Yatsenko, Svetlana A.;
- Jeffries, Elizabeth P.;
- Surti, Urvashi;
- Ketterer, Deborah M.;
- Afzal, Sibtain;
- Ramzan, Khushnooda;
- Haque, Muhammad Faiyaz-UI;
- Huaiyang Jiang;
- Trakselis, Michael A.;
- Rajkovic, Aleksandar
Publication type:
Article
Clinical trial demonstrates exercise following bariatric surgery improves insulin sensitivity.
Published in:
2015
By:
- Coen, Paul M.;
- Tanner, Charles J.;
- Helbling, Nicole L.;
- Dubis, Gabriel S.;
- Hames, Kazanna C.;
- Hui Xie;
- Eid, George M.;
- Stefanovic-Racic, Maja;
- Toledo, Frederico G. S.;
- Jakicic, John M.;
- Houmard, Joseph A.;
- Coodpaster, Bret H.;
- Xie, Hui;
- Goodpaster, Bret H
Publication type:
journal article
Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 234, doi. 10.1172/JCI77888
By:
- Zhifang Dong;
- Huili Han;
- Hongjie Li;
- Yanrui Bai;
- Wei Wang;
- Man Tu;
- Yan Peng;
- Limin Zhou;
- Wenting He;
- Xiaobin Wu;
- Tao Tan;
- Mingjing Liu;
- Xiaoyan Wu;
- Weihui Zhou;
- Wuyang Jin;
- Shu Zhang;
- Sacktor, Todd Charlton;
- Tingyu Li;
- Weihong Song;
- Yu Tian Wang
Publication type:
Article
Human pDCs preferentially sense enveloped hepatitis A virions.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 169, doi. 10.1172/JCI77527
By:
- Zongdi Feng;
- You Li;
- McKnight, Kevin L.;
- Hensley, Lucinda;
- Lanford, Robert E.;
- Walker, Christopher M.;
- Lemon, Stanley M.
Publication type:
Article
Rare codons capacitate Kras-driven de novo tumorigenesis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 222, doi. 10.1172/JCI77627
By:
- Pershing, Nicole L. K.;
- Lampson, Benjamin L.;
- Belsky, Jason A.;
- Kaltenbrun, Erin;
- MacAlpine, David M.;
- Counter, Christopher M.
Publication type:
Article
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 194, doi. 10.1172/JCI76012
By:
- Cerriets, Valerie A.;
- Kishton, Rigel J.;
- Nichols, Amanda C.;
- Macintyre, Andrew N.;
- Makoto Inoue;
- Ilkayeva, Olga;
- Winter, Peter S.;
- Xiaojing Liu;
- Priyadharshini, Bhavana;
- Slawinska, Marta E.;
- Haeberli, Lea;
- Huck, Catherine;
- Turka, Laurence A.;
- Wood, Kris C.;
- Hale, Laura P.;
- Smith, Paul A.;
- Schneider, Martin A.;
- Maclver, Nancie J.;
- Locasale, Jason W.;
- Newgard, Christopher B.
Publication type:
Article
Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 183, doi. 10.1172/JCI73615
By:
- Ceun Hyang Kim;
- Gyun-Sik Oh;
- Jin Yoon;
- Gang Gu Lee;
- Ki-Up Lee;
- Seung-Whan Kim
Publication type:
Article
Protein tyrosine phosphatase-σ regulates hematopoietic stem cell-repopulating capacity.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 177, doi. 10.1172/JCI77866
By:
- Quarmyne, Mamie;
- Doan, Phuong L.;
- Himburg, Heather A.;
- Xiao Yan;
- Mai Nakamura;
- Liman Zhao;
- Chao, Nelson J.;
- Chute, John P.
Publication type:
Article
Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis.
Published in:
2015
By:
- Menon, Madhav C.;
- Chuang, Peter Y.;
- Zhengzhe Li;
- Chengguo Wei;
- Weijia Zhang;
- Yi Luan;
- Zhengzi Yi;
- Huabao Xiong;
- Woytovich, Christopher;
- Greene, Ilana;
- Overbey, Jessica;
- Rosales, Ivy;
- Bagiella, Emilia;
- Rong Chen;
- Meng Ma;
- Li Li;
- Wei Ding;
- Djamali, Arjang;
- Saminego, Millagros;
- O'Connell, Philip J.
Publication type:
journal article
Survivin-specific T cell receptor targets tumor but not T cells.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 157, doi. 10.1172/JCI75876
By:
- Arber, Caroline;
- Xiang Feng;
- Abhyankar, Harshal;
- Romero, Errika;
- Meng-Fen Wu;
- Heslop, Helen E.;
- Barth, Patrick;
- Dotti, Cianpietro;
- Savoldo, Barbara
Publication type:
Article
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 141, doi. 10.1172/JCI75852
By:
- Gomez, Ivan C.;
- MacKenna, Deidre A.;
- Johnson, Bryce G.;
- Kaimal, Vivek;
- Roach, Allie M.;
- Shuyu Ren;
- Naoki Nakagawa;
- Cuiyan Xin;
- Newitt, Rick;
- Pandya, Shweta;
- Tai-He Xia;
- Xueqing Liu;
- Borza, Dorin-Bogdan;
- Grafals, Monica;
- Shankland, Stuart J.;
- Himmelfarb, Jonathan;
- Portilla, Didier;
- Shiguang Liu;
- Chau, B. Nelson;
- Duffield, Jeremy S.
Publication type:
Article
Podoplanin negatively regulates CD4+ effector T cell responses.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 129, doi. 10.1172/JCI74685
By:
- Peters, Anneli;
- Burkett, Patrick R.;
- Sobel, Raymond A.;
- Buckley, Christopher D.;
- Watson, Steve P.;
- Bettelli, Estelle;
- Kuchroo, Vijay K.
Publication type:
Article
mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 117, doi. 10.1172/JCI73935
By:
- Gleason, Catherine E.;
- Frindt, Gustavo;
- Chih-jen Cheng;
- Ng, Michael;
- Kidwai, Atif;
- Rashmi, Priyanka;
- Lang, Florian;
- Baum, Michel;
- Palmer, Lawrence G.;
- Pearce, David
Publication type:
Article
Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 105, doi. 10.1172/JCI65654
By:
- Byrne, Leah C.;
- Dalkara, Deniz;
- Luna, Gabriel;
- Fisher, Steven K.;
- Clérin, Emmanuelle;
- Sahel, Jose-Alain;
- Léveillard, Thierry;
- Flannery, John G.
Publication type:
Article
AGS, SLE, and RNASEH2 mutations: translating insights into therapeutic advances.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 102, doi. 10.1172/jci78533
By:
- Pendergraft III, William F.;
- Means, Terry K.
Publication type:
Article
Bringing home the bacon? The next step in cardiac sodium channelopathies.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 99, doi. 10.1172/JCI80014
By:
- Wilde, Arthur A. M.;
- Postema, Pieter C.
Publication type:
Article
The genetics of hepatitis C virus underlie its ability to escape humoral immunity.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 97, doi. 10.1172/JCI79424
By:
- Kolls, Jay K.;
- Szabo, Gyongyi
Publication type:
Article
Immune therapy for treating type 1 diabetes: challenging existing paradigms.
Published in:
2015
By:
- Skyler, Jay S.
Publication type:
journal article
The functional and pathologic relevance of autophagy proteases.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 33, doi. 10.1172/JCI73940
By:
- Fernández, Álvaro F.;
- López-Otín, Carlos
Publication type:
Article
Essential role for autophagy in life span extension.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 85, doi. 10.1172/JCI73946
By:
- Madeo, Frank;
- Zimmermann, Andreas;
- Maiuri, Maria Chiara;
- Kroemer, Guido
Publication type:
Article
mTOR: a pharmacologic target for autophagy regulation.
Published in:
2015
By:
- Young Chul Kim;
- Kun-Liang Guan;
- Kim, Young Chul;
- Guan, Kun-Liang
Publication type:
journal article
Development of autophagy inducers in clinical medicine.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 14, doi. 10.1172/JCI73938
By:
- Levine, Beth;
- Packer, Milton;
- Codogno, Patrice
Publication type:
Article
Pharmacologic agents targeting autophagy.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 5, doi. 10.1172/JCI73937
By:
- Vakifahmetoglu-Norberg, Helin;
- Hong-guang Xia;
- Junying Yuan
Publication type:
Article
Autophagy in cellular metabolism and cancer.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 47, doi. 10.1172/JCI73942
By:
- Xuejun Jiang;
- Overholtzer, Michael;
- Thompson, Craig B.
Publication type:
Article
Immunologic manifestations of autophagy.
Published in:
2015
By:
- Deretic, Vojo;
- Kimura, Tomonori;
- Timmins, Graham;
- Moseley, Pope;
- Chauhan, Santosh;
- Mandell, Michael
Publication type:
journal article
Autophagy and neurodegeneration.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 65, doi. 10.1172/JCI73944
By:
- Frake, Rebecca A.;
- Ricketts, Thomas;
- Menzies, Fiona M.;
- Rubinsztein, David C.
Publication type:
Article
Autophagy in cardiovascular biology.
Published in:
2015
By:
- Lavandero, Sergio;
- Chiong, Mario;
- Rothermel, Beverly A.;
- Hill, Joseph A.
Publication type:
journal article
Autophagy: a druggable process that is deregulated in aging and human disease.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 1, doi. 10.1172/JCI78652
By:
- Kroemer, Guido
Publication type:
Article
The role for autophagy in cancer.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 42, doi. 10.1172/JCI73941
By:
- White, Eileen
Publication type:
Article

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