Works in Journal of Clinical Investigation, 2011, Vol 121, Issue 3
Results: 43
RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it.
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- journal article
Adherent-invasive E. coli in Crohn disease: bacterial "agent provocateur".
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Unraveling virus-induced lymphomagenesis.
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Upper urinary tract pacemaker cells join the GLI club.
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Food allergy.
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Corrigendum.
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- Correction Notice
Dangerous pregnancies.
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- Book Review
The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region.
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Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells.
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Erratum.
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- Correction Notice
A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children.
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Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells.
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Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.
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GLI3 repressor controls functional development of the mouse ureter.
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IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B.
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Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in mice.
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- 2011
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Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1.
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- 2011
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NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children.
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A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans.
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Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.
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Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype.
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Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4+ T cells.
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The pain chronicles.
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- Book Review
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.
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Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.
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CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression.
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Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.
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MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation.
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Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections.
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An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice.
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Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay.
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Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance.
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SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans.
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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers.
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Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae.
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Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation.
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Pier Paolo Pandolfi wins Pezcoller-AACR International Award for Cancer Research.
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- 2011
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- Interview
IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.
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Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
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Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients.
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Hunk is required for HER2/neu-induced mammary tumorigenesis.
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Genetic control of hepatitis A severity and susceptibility to allergy.
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Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.
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