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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.
Published in:
2007
By:
- Yvan-Charvet, Laurent;
- Ranalletta, Mollie;
- Nan Wang;
- Seongah Han;
- Terasaka, Naoki;
- Rong Li;
- Welch, Carrie;
- Tall, Alan R.;
- Wang, Nan;
- Han, Seongah;
- Li, Rong
Publication type:
journal article
FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.
Published in:
2007
By:
- Zuo, Tao;
- Liu, Runhua;
- Zhang, Huiming;
- Chang, Xing;
- Liu, Yan;
- Wang, Lizhong;
- Zheng, Pan;
- Liu, Yang
Publication type:
journal article
TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.
Published in:
2007
By:
- Calzascia, Thomas;
- Pellegrini, Marc;
- Hall, Håkan;
- Sabbagh, Laurent;
- Ono, Nobuyuki;
- Elford, Alisha R;
- Mak, Tak W;
- Ohashi, Pamela S
Publication type:
journal article
Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 4022, doi. 10.1172/JCI32829
By:
- Yan Rao;
- Zhong-Wu Liu;
- Borok, Erzsebet;
- Rabenstein, Rebecca L.;
- Shanabrough, Marya;
- Min Lu;
- Picciotto, Marina R.;
- Horvath, Tamas L.;
- Xiao-Bing Gao
Publication type:
Article
OX40-OX40L interactions: a promising therapeutic target for allergic diseases?
Published in:
2007
By:
- Wang, Yui-Hsi;
- Liu, Yong-Jun
Publication type:
journal article
Bone marrow-derived circulating progenitor cells fail to transdifferentiate into adipocytes in adult adipose tissues in mice.
Published in:
2007
By:
- Koh, Young Jun;
- Kang, Shinae;
- Lee, Hyuek Jong;
- Choi, Tae-Saeng;
- Lee, Ho Sub;
- Cho, Chung-Hyun;
- Koh, Gou Young
Publication type:
journal article
Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans.
Published in:
2007
By:
- Panicot-Dubois, Laurence;
- Thomas, Grace M;
- Furie, Barbara C;
- Furie, Bruce;
- Lombardo, Dominique;
- Dubois, Christophe
Publication type:
journal article
Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling.
Published in:
2007
By:
- Hu, Kebin;
- Wu, Chuanyue;
- Mars, Wendy M;
- Liu, Youhua
Publication type:
journal article
Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.
Published in:
2007
By:
- Burkart, Eileen M;
- Sambandam, Nandakumar;
- Han, Xianlin;
- Gross, Richard W;
- Courtois, Michael;
- Gierasch, Carolyn M;
- Shoghi, Kooresh;
- Welch, Michael J;
- Kelly, Daniel P
Publication type:
journal article
The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.
Published in:
2007
By:
- Suliman, Hagir B;
- Carraway, Martha Sue;
- Ali, Abdelwahid S;
- Reynolds, Chrystal M;
- Welty-Wolf, Karen E;
- Piantadosi, Claude A
Publication type:
journal article
An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic.
Published in:
2007
By:
- Fernández, Ariel;
- Sanguino, Angela;
- Peng, Zhenghong;
- Ozturk, Eylem;
- Chen, Jianping;
- Crespo, Alejandro;
- Wulf, Sarah;
- Shavrin, Aleksander;
- Qin, Chaoping;
- Ma, Jianpeng;
- Trent, Jonathan;
- Lin, Yvonne;
- Han, Hee-Dong;
- Mangala, Lingegowda S;
- Bankson, James A;
- Gelovani, Juri;
- Samarel, Allen;
- Bornmann, William;
- Sood, Anil K;
- Lopez-Berestein, Gabriel
Publication type:
journal article
Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons.
Published in:
2007
By:
- Rao, Yan;
- Liu, Zhong-Wu;
- Borok, Erzsebet;
- Rabenstein, Rebecca L;
- Shanabrough, Marya;
- Lu, Min;
- Picciotto, Marina R;
- Horvath, Tamas L;
- Gao, Xiao-Bing
Publication type:
journal article
Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.
Published in:
2007
By:
- Hu, Chang-yun;
- Rodriguez-Pinto, Daniel;
- Du, Wei;
- Ahuja, Anupama;
- Henegariu, Octavian;
- Wong, F Susan;
- Shlomchik, Mark J;
- Wen, Li
Publication type:
journal article
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.
Published in:
2007
By:
- Liu, Tianju;
- Chung, Myoung Ja;
- Ullenbruch, Matthew;
- Yu, Hongfeng;
- Jin, Hong;
- Hu, Biao;
- Choi, Yoon Young;
- Ishikawa, Fuyuki;
- Phan, Sem H
Publication type:
journal article
OX40-OX40L interactions: a promising therapeutic target for allergic diseases?
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3655, doi. 10.1172/JCI34182
By:
- Yui-Hsi Wang;
- Yong-Jun Liu
Publication type:
Article
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.
Published in:
2007
By:
- Gao, Sizhi Paul;
- Mark, Kevin G;
- Leslie, Kenneth;
- Pao, William;
- Motoi, Noriko;
- Gerald, William L;
- Travis, William D;
- Bornmann, William;
- Veach, Darren;
- Clarkson, Bayard;
- Bromberg, Jacqueline F
Publication type:
journal article
Recombinant adeno-associated virus vectors induce functionally impaired transgene product-specific CD8+ T cells in mice.
Published in:
2007
By:
- Lin, Shih-Wen;
- Hensley, Scott E;
- Tatsis, Nia;
- Lasaro, Marcio O;
- Ertl, Hildegund C J
Publication type:
journal article
An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 4044, doi. 10.1172/JCI32373
By:
- Ariel Fernández;
- Angela Sanguino;
- Zhenghong Peng;
- Eylem Ozturk;
- Jianping Chen;
- Alejandro Crespo;
- Sarah Wulf;
- Aleksander Shavrin;
- Chaoping Qin;
- Jianpeng Ma;
- Jonathan Trent;
- Yvonne Lin;
- Hee-Dong Han;
- Lingegowda S. Mangala;
- James A. Bankson;
- Juri Gelovani;
- Allen Samarel;
- William Bornmann;
- Anil K. Sood;
- Gabriel Lopez-Berestein
Publication type:
Article
Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.
Published in:
2007
By:
- Regard, Jean B.;
- Kataoka, Hiroshi;
- Cano, David A.;
- Camerer, Eric;
- Liya Yin;
- Yao-Wu Zheng;
- Scanlan, Thomas S.;
- Hebrok, Matthias;
- Coughlin, Shaun R.;
- Yin, Liya;
- Zheng, Yao-Wu
Publication type:
journal article
Milk fat globule-EGF factor 8/lactadherin plays a crucial role in maintenance and repair of murine intestinal epithelium.
Published in:
2007
By:
- Bu, Heng-Fu;
- Zuo, Xiu-Li;
- Wang, Xiao;
- Ensslin, Michael A;
- Koti, Vjola;
- Hsueh, Wei;
- Raymond, Adam S;
- Shur, Barry D;
- Tan, Xiao-Di
Publication type:
journal article
The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.
Published in:
2007
By:
- Hanai, Jun-ichi;
- Cao, Peirang;
- Tanksale, Preeti;
- Imamura, Shintaro;
- Koshimizu, Eriko;
- Zhao, Jinghui;
- Kishi, Shuji;
- Yamashita, Michiaki;
- Phillips, Paul S;
- Sukhatme, Vikas P;
- Lecker, Stewart H
Publication type:
journal article
PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis.
Published in:
2007
By:
- Belguise, Karine;
- Sonenshein, Gail E.
Publication type:
journal article
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland.
Published in:
2007
By:
- Sansone, Pasquale;
- Storci, Gianluca;
- Tavolari, Simona;
- Guarnieri, Tiziana;
- Giovannini, Catia;
- Taffurelli, Mario;
- Ceccarelli, Claudio;
- Santini, Donatella;
- Paterini, Paola;
- Marcu, Kenneth B.;
- Chieco, Pasquale;
- Bonafè, Massimiliano;
- Bonafè, Massimiliano
Publication type:
journal article
The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3940, doi. 10.1172/JCI32741
By:
- Jun-ichi Hanai;
- Peirang Cao;
- Tanksale, Preeti;
- Imamura, Shintaro;
- Koshimizu, Eriko;
- Jinghui Zhao;
- Kishi, Shuji;
- Yamashita, Michiaki;
- Phillips, Paul S.;
- Sukhatme, Vikas P.;
- Lecker, Stewart H.
Publication type:
Article
Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene.
Published in:
2007
By:
- Selva, David M.;
- Hogeveen, Kevin N.;
- Innis, Sheila M.;
- Hammond, Geoffrey L.
Publication type:
journal article
Deletion of TLR5 results in spontaneous colitis in mice.
Published in:
2007
By:
- Vijay-Kumar, Matam;
- Sanders, Catherine J.;
- Taylor, Rebekah T.;
- Kumar, Amrita;
- Aitken, Jesse D.;
- Sitaraman, Shanthi V.;
- Neish, Andrew S.;
- ematsu, Satoshi;
- Akira, Shizuo;
- Williams, Ifor R.;
- Gewirtz, Andrew T.;
- Uematsu, Satoshi
Publication type:
journal article
The parathyroid is a target organ for FGF23 in rats.
Published in:
2007
By:
- Ben-Dov, Iddo Z.;
- Galitzer, Hillel;
- Lavi-Moshayoff, Vardit;
- Goetz, Regina;
- Kuro-o, Makoto;
- Mohammadi, Moosa;
- Sirkis, Roy;
- Naveh-Many, Tally;
- Silver, Justin
Publication type:
journal article
STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3890, doi. 10.1172/JCI33010
By:
- Zan Huang;
- Richmond, Terri D.;
- Muntean, Andrew G.;
- Barber, Dwayne L.;
- Weiss, Mitchell J.;
- Crispino, John D.
Publication type:
Article
von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Published in:
2007
By:
- Hickey, Michele M.;
- Lam, Jennifer C.;
- Bezman, Natalie A.;
- Rathmell, W. Kimryn;
- Simon, M. Celeste
Publication type:
journal article
Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri.
Published in:
2007
By:
- Jurisicova, Andrea;
- Taniuchi, Asako;
- Han Li;
- Yuan Shang;
- Antenos, Monica;
- Detmar, Jacqui;
- Jing Xu;
- Matikainen, Tiina;
- Benito^Hernández, Adalberto;
- Nunez, Gabriel;
- Casper, Robert F.;
- Li, Han;
- Shang, Yuan;
- Xu, Jing;
- Benito Hernández, Adalberto
Publication type:
journal article
Recombinant adeno-associated virus vectors induce functionally impaired transgene product--specific CD8+ T cells in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3958, doi. 10.1172/JCI33138
By:
- Shih-Wen Lin;
- Hensley, Scott E.;
- Tatsis, Nia;
- Lasaro, Marcio O.;
- Ertl, Hildegund C. J.
Publication type:
Article
Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy.
Published in:
2007
By:
- Wheeler, Thurman M.;
- Lueck, John D.;
- Swanson, Maurice S.;
- Dirksen, Robert T.;
- Thornton, Charles A.
Publication type:
journal article
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Published in:
2007
By:
- Seshasayee, Dhaya;
- Lee, Wyne P.;
- Meijuan Zhou;
- Jean Shu;
- Suto, Eric;
- Juan Zhang;
- Diehl, Laurie;
- Austin, Cary D.;
- Gloria Meng, Y.;
- Martha Tan;
- Bullens, Sherron L.;
- Seeber, Stefan;
- Fuentes, Maria E.;
- Labrijn, Aran F.;
- Graus, Yvo M. F.;
- Miller, Lisa A.;
- Schelegle, Edward S.;
- Hyde, Dallas M.;
- Wu, Lawren C.;
- Hymowitz, Sarah G.
Publication type:
journal article
Nuclear receptors PPARβ/δ and PPARα direct distinct metabolic regulatory programs in the mouse heart.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3930, doi. 10.1172/JCI32578
By:
- Burkart, Eileen M.;
- Sambandam, Nandakumar;
- Xianlin Han;
- Gross, Richard W.;
- Courtois, Michael;
- Gierasch, Carolyn M.;
- Shoghi, Kooresh;
- Welch, Michael J.;
- Kelly, Daniel P.
Publication type:
Article
CD200 is induced by ERK and is a potential therapeutic target in melanoma.
Published in:
2007
By:
- Petermann, Kimberly B.;
- Rozenberg, Gabriela I.;
- Zedek, Daniel;
- Groben, Pamela;
- McKinnon, Karen;
- Buehler, Christin;
- Kim, William Y.;
- Shields, Janiel M.;
- Penland, Shannon;
- Bear, James E.;
- Thomas, Nancy E.;
- Serody, Jonathan S.;
- Sharpless, Norman E.
Publication type:
journal article
Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3857, doi. 10.1172/JCI32405
By:
- Chang-yun Hu;
- Rodriguez-Pinto, Daniel;
- Wei Du;
- Ahuja, Anupama;
- Henegariu, Octavian;
- Susan Wong, F.;
- Shlomchik, Mark J.;
- Li Wen
Publication type:
Article
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3846, doi. 10.1172/JCI31871
By:
- Sizhi Paul Gao;
- Mark, Kevin G.;
- Leslie, Kenneth;
- Pao, William;
- Motoi, Noriko;
- Gerald, William L.;
- Travis, William D.;
- Bornmann, William;
- Veach, Darren;
- Clarkson, Bayard;
- Bromberg, Jacqueline F.
Publication type:
Article
TNF-α is critical for antitumor but not antiviral T cell immunity in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3833, doi. 10.1172/JCI32567
By:
- Calzascia, Thomas;
- Pellegrini, Marc;
- Hall, Håkan;
- Sabbagh, Laurent;
- Ono, Nobuyuki;
- Elford, Alisha R.;
- Mak, Tak W.;
- Ohashi, Pamela S.
Publication type:
Article
Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor--related protein 1--mediated integrin signaling.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3821, doi. 10.1172/JCI32301
By:
- Kebin Hu;
- Chuanyue Wu;
- Mars, Wendy M.;
- Youhua Liu
Publication type:
Article
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.
Published in:
2007
By:
- Higgins, Debra F.;
- Kimura, Kuniko;
- Bernhardt, Wanja M.;
- Shrimanker, Nikita;
- Akai, Yasuhiro;
- Hohenstein, Bernd;
- Saito, Yoshihiko;
- Johnson, Randall S.;
- Kretzler, Matthias;
- Cohen, Clemens D.;
- Eckardt, Kai-Uwe;
- Iwano, Masayuki;
- Haase, Volker H.
Publication type:
journal article
Telomerase activity is required for bleomycininduced pulmonary fibrosis in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3800, doi. 10.1172/JCI32369
By:
- Tianju Liu;
- Myoung Ja Chung;
- Ullenbruch, Matthew;
- Hongfeng Yu;
- Hong Jin;
- Biao Hu;
- Yoon Young Choi;
- Fuyuki Ishikawa;
- Sem H. Phan
Publication type:
Article
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3786, doi. 10.1172/JCI32285
By:
- Gasse, Pamela;
- Mary, Caroline;
- Guenon, Isabelle;
- Noulin, Nicolas;
- Charron, Sabine;
- Schnyder-Candrian, Silvia;
- Schnyder, Bruno;
- Akira, Shizuo;
- Quesniaux, Valérie F. J.;
- Lagente, Vincent;
- Ryffel, Bernhard;
- Couillin, Isabelle
Publication type:
Article
Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis.
Published in:
2007
By:
- Babu, Ashok N.;
- Murakawa, Tomohiro;
- Thurman, Joshua M.;
- Miller, Edmund J.;
- Henson, Peter M.;
- Zamora, Martin R.;
- Voelkel, Norbert F.;
- Nicolls, Mark R.
Publication type:
journal article
FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3765, doi. 10.1172/JCI32538
By:
- Tao Zuo;
- Runhua Liu;
- Huiming Zhang;
- Xing Chang;
- Yan Liu;
- Lizhong Wang;
- Pan Zheng;
- Yang Liu
Publication type:
Article
CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3753, doi. 10.1172/JCI32481
By:
- Xiuwei Tang;
- Yucui Zhu;
- Lydia Han;
- Kim, Arianna L.;
- Kopelovich, Levy;
- Bickers, David R.;
- Athar, Mohammad
Publication type:
Article
Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia.
Published in:
2007
By:
- Tan, Serena Y.;
- Rosenthal, Julie;
- Xiao-Qing Zhao;
- Francis, Richard J.;
- Chatterjee, Bishwanath;
- Sabol, Steven L.;
- Linask, Kaari L.;
- Bracero, Luciann;
- Connelly, Patricia S.;
- Daniels, Mathew P.;
- Qing Yu;
- Omran, Heymut;
- Leatherbury, Linda;
- Lo, Cecilia W.;
- Zhao, Xiao-Qing;
- Yu, Qing
Publication type:
journal article
The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3730, doi. 10.1172/JCI32967
By:
- Hagir B. Suliman;
- Martha Sue Carraway;
- Abdelwahid S. Ali;
- Chrystal M. Reynolds;
- Karen E. Welty-Wolf;
- Claude A. Piantadosi
Publication type:
Article
Visual phenotype in Williams-Beuren syndrome challenges magnocellular theories explaining human neurodevelopmental visual cortical disorders.
Published in:
2007
By:
- Castelo-Branco, Miguel;
- Mendes, Mafalda;
- Sebastião, Ana Raquel;
- Reis, Aldina;
- Soares, Mário;
- Saraiva, Jorge;
- Bernardes, Rui;
- Flores, Raquel;
- Pérez-Jurado, Luis;
- Silva, Eduardo;
- Sebastião, Ana Raquel;
- Soares, Mário;
- Pérez-Jurado, Luis
Publication type:
journal article
Bile salt--dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3708, doi. 10.1172/JCI32655
By:
- Laurence Panicot-Dubois;
- Grace M. Thomas;
- Barbara C. Furie;
- Bruce Furie;
- Dominique Lombardo;
- Christophe Dubois
Publication type:
Article
Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice.
Published in:
2007
By:
- Shing, Danielle C.;
- Trubia, Maurizio;
- Marchesi, Francesco;
- Radaelli, Enrico;
- Belloni, Elena;
- Tapinassi, Cinzia;
- Scanziani, Eugenio;
- Mecucci, Cristina;
- Crescenzi, Barbara;
- Lahortiga, Idoya;
- Odero, Maria D.;
- Zardo, Giuseppe;
- Gruszka, Alicja;
- Minucci, Saverio;
- Di^Fiore, Pier Paolo;
- Pelicci, Pier Giuseppe
Publication type:
journal article

Found: 69