Found: 24
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Halistanol sulfates I and J, new SIRT1-3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 273, doi. 10.1038/ja.2017.145
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Synthesis and SARs of novel lincomycin derivatives Part 5: optimization of lincomycin analogs exhibiting potent antibacterial activities by chemical modification at the 6- and 7-positions.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 298, doi. 10.1038/ja.2017.114
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Challenges and discoveries in the total synthesis of complex polyketide natural products.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 215, doi. 10.1038/ja.2017.111
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Biography of Professor Nicolaou: a journey to the extremes of molecular complexity.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 149, doi. 10.1038/ja.2017.144
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Large-scale preparation of key building blocks for the manufacture of fully synthetic macrolide antibiotics.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 318, doi. 10.1038/ja.2017.116
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Enantiospecific total synthesis of the squalene synthase inhibitors (-)-CJ-13,982 and its enantiomer from a common intermediate.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 234, doi. 10.1038/ja.2017.127
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Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 333, doi. 10.1038/ja.2017.146
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Total synthesis of (+)-lysergic acid.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 240, doi. 10.1038/ja.2017.80
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Using experimental evolution to identify druggable targets that could inhibit the evolution of antimicrobial resistance.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 279, doi. 10.1038/ja.2017.108
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Formal synthesis of englerin A utilizing regio- and diastereoselective [4+3] cycloaddition.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 257, doi. 10.1038/ja.2017.91
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Synthesis of deoxyelephantopin analogues.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 248, doi. 10.1038/ja.2017.132
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Corrigendum: Total synthesis and absolute configuration of avenolide, extracellular factor in Streptomyces avermitilis.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 348, doi. 10.1038/ja.2017.148
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A three-component coupling approach to the ACE-ring substructure of C19-diterpene alkaloids.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 326, doi. 10.1038/ja.2017.69
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Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 287, doi. 10.1038/ja.2017.86
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Professor KC Nicolaou expanded the world of synthetic organic chemistry by total synthesis and his laboratories have fostered many talented researchers.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 151, doi. 10.1038/ja.2017.147
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Chemotherapeutics overcoming nonsense mutation-associated genetic diseases: medicinal chemistry of negamycin.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 205, doi. 10.1038/ja.2017.112
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A brief history of antibiotics and select advances in their synthesis.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 153, doi. 10.1038/ja.2017.62
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Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 268, doi. 10.1038/ja.2017.77
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Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 345, doi. 10.1038/ja.2017.60
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Synthesis of unique spirocyclic orthoester-type derivatives of isothiazolo[4,3-d]pyrimidine nucleosides.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 342, doi. 10.1038/ja.2017.87
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Albiducins A and B, salicylaldehyde antibiotics from the ash tree-associated saprotrophic fungus Hymenoscyphus albidus.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 339, doi. 10.1038/ja.2017.66
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Corrigendum: Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 349, doi. 10.1038/ja.2017.149
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Total synthesis of architecturally complex indole terpenoids: strategic and tactical evolution.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 185, doi. 10.1038/ja.2017.94
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Progress towards the total synthesis of hamigerans C and D: a direct approach to an elaborated 6-7-5 carbocyclic core.
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- Journal of Antibiotics, 2018, v. 71, n. 2, p. 263, doi. 10.1038/ja.2017.96
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