Works matching IS 00121797 AND DT 2002 AND VI 51

Results: 677

Genetic manipulations of fatty acid metabolism in beta-cells are associated with dysregulated insulin secretion.

Published in:

2002

By:

Eto, Kazuhiro;
Yamashita, Tokuyuki;
Matsui, Junji;
Terauchi, Yasuo;
Noda, Mitsuhiko;
Kadowaki, Takashi

Publication type:

journal article

Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics.

Published in:

2002

By:

Matschinsky, Franz M

Publication type:

journal article

Regulation of intracellular Ca2+ stores by multiple Ca2+-releasing messengers.

Published in:

2002

By:

Cancela, Jose M;
Petersen, Ole H

Publication type:

journal article

Activation of nuclear factor-kappaB by depolarization and Ca(2+) influx in MIN6 insulinoma cells.

Published in:

2002

By:

Bernal-Mizrachi, Ernesto;
Wen, Wu;
Shornick, Michael;
Permutt, M Alan

Publication type:

journal article

Genetics of obesity and type 2 diabetes: tracking pathogenic traits during the predisease period.

Published in:

2002

By:

Bougnères P;
Bougnères, Pierre

Publication type:

journal article

Increased insulin resistance in obese children who have both 972 IRS-1 and 1057 IRS-2 polymorphisms.

Published in:

2002

By:

Le Fur S;
Le Stunff C;
Bougnères P;
Le Fur, Sophie;
Le Stunff, Catherine;
Bougnères, Pierre

Publication type:

journal article

Challenges and strategies for investigating the genetic complexity of common human diseases.

Published in:

2002

By:

Rich SS;
Concannon P;
Rich, Stephen S;
Concannon, Patrick

Publication type:

journal article

Proinsulin 2 knockout NOD mice: a model for genetic variation of insulin gene expression in type 1 diabetes.

Published in:

2002

By:

Dubois-Lafforgue, Danièle;
Mogenet, Laurent;
Thébault, Karine;
Jami, Jacques;
Krief, Patricia;
Boitard, Christian;
Dubois-Lafforgue, Danièle;
Thébault, Karine

Publication type:

journal article

Activation of Nuclear Factor-κB by Depolarization and Ca[sup2+] Influx in MIN6 Insulinoma Cells.

Published in:

Diabetes, 2002, v. 51, p. S484, doi. 10.2337/diabetes.51.2007.S484

By:

Bernal-Mizrachi, Ernesto;
Wen, Wu;
Shornick, Michael;
Permutt, M. Alan

Publication type:

Article

Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice.

Published in:

2002

By:

Unno, Michiaki;
Nata, Koji;
Noguchi, Naoya;
Narushima, Yoichi;
Akiyama, Takako;
Ikeda, Takayuki;
Nakagawa, Kei;
Takasawa, Shin;
Okamoto, Hiroshi

Publication type:

journal article

Prolonged in vitro exposure to autoantibodies against CD38 impairs the function and survival of human pancreatic islets.

Published in:

2002

By:

Marchetti, Piero;
Antonelli, Alessandro;
Lupi, Roberto;
Marselli, Lorella;
Fallahi, Poupak;
Nesti, Claudia;
Baj, Germano;
Ferrannini, Ele

Publication type:

journal article

Recent Advances in the Okamoto Model The CD38-Cyclic ADP-Ribose Signal System and the Regenerating Gene Protein (Reg)-Reg Receptor System in Β-Cells.

Published in:

Diabetes, 2002, v. 51, p. S462, doi. 10.2337/diabetes.51.2007.S462

By:

Okamoto, Hiroshi;
Takasawa, Shin

Publication type:

Article

Endoplasmic reticulum stress and the development of diabetes: a review.

Published in:

2002

By:

Harding, Heather P.;
Ron, David

Publication type:

journal article

Two generations of insulinotropic imidazoline compounds.

Published in:

2002

By:

Efendic, Suad;
Efanov, Alexander M.;
Berggren, Per-Olof;
Zaitsev, Sergei V.

Publication type:

journal article

Glucagon-like peptide-1 receptor activation antagonizes voltage-dependent repolarizing K(+) currents in beta-cells: a possible glucose-dependent insulinotropic mechanism.

Published in:

2002

By:

MacDonald, Patrick E.;
Salapatek, Anne Marie F.;
Wheeler, Michael B.

Publication type:

journal article

The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion.

Published in:

2002

By:

MacDonald, Patrick E.;
El-kholy, Wasim;
Riedel, Michael J.;
Salapatek, Anne Marie F.;
Light, Peter E.;
Wheeler, Michael B.

Publication type:

journal article

Insulin Receptor Signaling and Sarco/Endoplasmic Reticulum Calcium ATPase in Β-Cells.

Published in:

Diabetes, 2002, v. 51, p. S427, doi. 10.2337/diabetes.51.2007.S427

By:

Borge, Prabakhar D.;
Moibi, Jacob;
Greene, Scott R.;
Trucco, Matteo;
Young, Robert A.;
Gao, Zhiyong;
Wolf, Bryan A.

Publication type:

Article

Glutaminolysis and insulin secretion: from bedside to bench and back.

Published in:

2002

By:

Kelly, Andrea;
Li, Changhong;
Gao, Zhiyong;
Stanley, Charles A.;
Matschinsky, Franz M.

Publication type:

journal article

Genetic Manipulation of Fatty Acid Metabolism in Β-Cells Are Associated With Dysregulated Insulin Secretion.

Published in:

Diabetes, 2002, v. 51, p. S414, doi. 10.2337/diabetes.51.2007.S414

By:

Eto, Kazuhiro;
Yamashita, Tokuyuki;
Matsui, Junji;
Terauchi, Yasuo;
Noda, Mitsuhiko;
Kadowaki, Takashi

Publication type:

Article

Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes.

Published in:

2002

By:

Prentki, Marc;
Joly, Erik;
El-Assaad, Wissal;
Roduit, Raphaël;
Roduit, Raphaël

Publication type:

journal article

Regulation of Pancreatic Β-Cell Glucokinase.

Published in:

Diabetes, 2002, v. 51, p. S394, doi. 10.2337/diabetes.51.2007.S394

By:

Matschinsky, Franz M.

Publication type:

Article

Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach.

Published in:

2002

By:

Newgard, Christopher B.;
Lu, Danhong;
Jensen, Mette Valentin;
Schissler, Jonathan;
Boucher, Anne;
Burgess, Shawn;
Sherry, A. Dean

Publication type:

journal article

Intracellular targeting of protein kinases and phosphatases.

Published in:

2002

By:

Alto, Neal;
Michel, Jennifer J. Carlisle;
Dodge, Kimberly L.;
Langeberg, Lorene K.;
Scott, John D.;
Carlisle Michel, Jennifer J

Publication type:

journal article

Gliclazide directly inhibits arginine-induced glucagon release.

Published in:

2002

By:

Cejvan, Kenan;
Coy, David H.;
Holst, Jens Juul;
Cerasi, Erol;
Efendic, Suad

Publication type:

journal article

Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.

Published in:

2002

By:

Lippiat, Jonathan D.;
Albinson, Sophie L.;
Ashcroft, Frances M.

Publication type:

journal article

Sulfonylurea Stimulation of Insulin Secretion.

Published in:

Diabetes, 2002, v. 51, p. S368, doi. 10.2337/diabetes.51.2007.S368

By:

Proks, Peter;
Reimann, Frank;
Green, Nick;
Gribble, Fiona;
Ashcroft, Frances

Publication type:

Article

The common single nucleotide polymorphism E23K in K(IR)6.2 sensitizes pancreatic beta-cell ATP-sensitive potassium channels toward activation through nucleoside diphosphates.

Published in:

2002

By:

Schwanstecher, Christina;
Neugebauer, Bettina;
Schulz, Miriam;
Schwanstecher, Mathias

Publication type:

journal article

Nucleotide Sensitivity of Pancreatic ATP-Sensitive Potassium and Type 2 Diabetes.

Published in:

Diabetes, 2002, v. 51, p. S358, doi. 10.2337/diabetes.51.2007.S358

By:

Schwanstecher, Christina;
Schwanstecher, Mathias

Publication type:

Article

Regulation of Inracellular Ca[sup2+] Stores by Multiple Ca[sup2+]-Releasing Messengers.

Published in:

Diabetes, 2002, v. 51, p. S349, doi. 10.2337/diabetes.51.2007.S349

By:

Cancela, Jose M.;
Petersen, Ole H.

Publication type:

Article

Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).

Published in:

2002

By:

Boileau, Pascal;
Wolfrum, Christian;
Shih, David Q.;
Yang, Tien-An;
Wolkoff, Allan W.;
Stoffel, Markus

Publication type:

journal article

Experimental models of transcription factor-associated maturity-onset diabetes of the young.

Published in:

2002

By:

Wang, Haiyan;
Hagenfeldt-Johansson, Kerstin;
Otten, Luc A.;
Gauthier, Benoit R.;
Herrera, Pedro L.;
Wollheim, Claes B.

Publication type:

journal article

Glucose-Regulated Gene Expression Maintaining the Glucose-Responsive State of Β-Cells.

Published in:

Diabetes, 2002, v. 51, p. S326, doi. 10.2337/diabetes.51.2007.S326

By:

Schuit, Frans;
Flamez, Daisy;
De Vos, Anick;
Pipeleers, Daniel

Publication type:

Article

Regulation of pdx-1 gene expression.

Published in:

2002

By:

Melloul, Danielle;
Marshak, Sonya;
Cerasi, Erol

Publication type:

journal article

Cellular basis of diabetic nephropathy: II. The transforming growth factor-beta system and diabetic nephropathy lesions in type 1 diabetes.

Published in:

2002

By:

Huang, Chunmei;
Kim, Youngki;
Caramori, Maria Luiza A;
Fish, Alfred J;
Rich, Stephen S;
Miller, Michael E;
Russell, Gregory B;
Mauer, Michael

Publication type:

journal article

Evidence for a novel type 1 diabetes susceptibility locus on chromosome 8.

Published in:

2002

By:

Sale, Michèle M.;
FitzGerald, Liesel M.;
Charlesworth, Jacinta C.;
Bowden, Donald W.;
Rich, Stephen S.;
Sale, Michèle M

Publication type:

journal article

Increased Insulin Resistance in Obese Children Who Have Both 972 IRS-1 and 1057 IRS-2 Polymorphisms.

Published in:

Diabetes, 2002, v. 51, p. S304, doi. 10.2337/diabetes.51.2007.S304

By:

Le Fur, Sophie;
Le Stunff, Catherine;
Bougnères, Pierre

Publication type:

Article

Combined effects of genetic and environmental factors on insulin resistance associated with reduced fetal growth.

Published in:

2002

By:

Jaquet D;
Trégouët DA;
Godefroy T;
Nicaud V;
Chevenne D;
Tiret L;
Czernichow P;
Lévy-Marchal C;
Jaquet, Delphine;
Trégouët, David A;
Godefroy, Thierry;
Nicaud, Viviane;
Chevenne, Didi;
Tiret, Laurence;
Czernichow, Paul;
Lévy-Marchal, Claire

Publication type:

journal article

Challenges and Strategies for Investigating the Genetic Complexity of Common Human Diseases.

Published in:

Diabetes, 2002, v. 51, p. S288, doi. 10.2337/diabetes.51.2007.S288

By:

Rich, Stephen S.;
Concannon, Patrick

Publication type:

Article

Regulation of Insulin Production In Search of Therapeutic Targets.

Published in:

2002

By:

Efendic, Suad;
Boitard, Christian;
Cerasi, Erol;
Ferrannini, Ele;
Henquin, Jean-Claude;
Steiner, Donald F.

Publication type:

Editorial

Searching for type 2 diabetes genes on chromosome 20.

Published in:

2002

By:

Permutt, Marshall Alan;
Wasson, Jonathan;
Love-Gregory, Latisha;
Ma, Jiyan;
Skolnick, Gary;
Suarez, Brian;
Lin, Jennifer;
Glaser, Benjamin

Publication type:

journal article

Lipolysis in the absence of hormone-sensitive lipase: evidence for a common mechanism regulating distinct lipases.

Published in:

2002

By:

Okazaki, Hiroaki;
Osuga, Jun-Ichi;
Tamura, Yoshiaki;
Yahagi, Naoya;
Tomita, Sachiko;
Shionoiri, Futoshi;
Iizuka, Yoko;
Ohashi, Ken;
Harada, Kenji;
Kimura, Satoshi;
Gotoda, Takanari;
Shimano, Hitoshi;
Yamada, Nobuhiro;
Ishibashi, Shun

Publication type:

journal article

Genetics of Obesity and Type 2 Diabetes Tracking Pathodgenic Traits During the Predisease Period.

Published in:

Diabetes, 2002, v. 51, p. S295, doi. 10.2337/diabetes.51.2007.S295

By:

Bougnères, Pierre

Publication type:

Article

The relative contributions of birth weight, weight change, and current weight to insulin resistance in contemporary 5-year-olds: the EarlyBird Study.

Published in:

2002

By:

Wilkin TJ;
Metcalf BS;
Murphy MJ;
Kirkby J;
Jeffery AN;
Voss LD;
Wilkin, Terence J;
Metcalf, Bradley S;
Murphy, Michael J;
Kirkby, Joanne;
Jeffery, Alison N;
Voss, Linda D

Publication type:

journal article

Errata.

Published in:: Diabetes, 2002, v. 51, n. 12, p. 3591, doi. 10.2337/diabetes.51.12.3591
Publication type:: Article

PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy.

Published in:

2002

By:

Hegele, Robert A.;
Cao, Henian;
Frankowski, Christy;
Mathews, Suresh T.;
Leff, Todd

Publication type:

journal article

Interleukin-1 receptor antagonist genotype is associated with coronary atherosclerosis in patients with type 2 diabetes.

Published in:

2002

By:

Marculescu, Rodrig;
Endler, Georg;
Schillinger, Martin;
Iordanova, Nelly;
Exner, Markus;
Hayden, Evelyn;
Huber, Kurt;
Wagner, Oswald;
Mannhalter, Christine

Publication type:

journal article

Cellular Basis of Diabetic Nephropathy.

Published in:

Diabetes, 2002, v. 51, n. 12, p. 3577, doi. 10.2337/diabetes.51.12.3577

By:

Huang, Chunmei;
Kim, Youngki;
Caramori, Maria Luiza A.;
Fish, Alfred J.;
Rich, Stephen S.;
Miller, Michael E.;
Russell, Gregory B.;
Mauer, Michael

Publication type:

Article

Sex-related bias and exclusion mapping of the nonrecombinant portion of chromosome Y in human type 1 diabetes in the isolated founder population of Sardinia.

Published in:

2002

By:

Contu, Daniela;
Morelli, Laura;
Zavattari, Patrizia;
Lampis, Rosanna;
Angius, Efisio;
Frongia, Paola;
Murru, Daniela;
Maioli, Mario;
Francalacci, Paolo;
Todd, John A.;
Cucca, Francesco

Publication type:

journal article

A quantitative trait locus influencing type 2 diabetes susceptibility maps to a region on 5q in an extended French family.

Published in:

2002

By:

Martin, Lisa J.;
Comuzzie, Anthony G.;
Dupont, Sophie;
Vionnet, Nathalie;
Dina, Christian;
Gallina, Sophie;
Houari, Mouna;
Blangero, John;
Froguel, Philippe

Publication type:

journal article

Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.

Published in:

2002

By:

Rasmussen, Søren K.;
Urhammer, Søren A.;
Berglund, Lars;
Jensen, Jan N.;
Hansen, Lars;
Echwald, Søren M.;
Borch-Johnsen, Knut;
Horikawa, Yukio;
Mashima, Hirosato;
Lithell, Hans;
Cox, Nancy J.;
Hansen, Torben;
Bell, Graeme I.;
Pedersen, Oluf;
Rasmussen, Søren K;
Urhammer, Søren A;
Echwald, Søren M

Publication type:

journal article