Works matching IS 00099236 AND DT 2025 AND VI 117 AND IP 3

Results: 30

Impact of Chronic Inflammatory Diseases on Clinical Pharmacokinetics of Antibody‐Based Therapeutic Proteins.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 646, doi. 10.1002/cpt.3513

By:

Tian, Xiaofan;
Yu, Yichao;
Neeli, Harshith;
Jappar, Dilara

Publication type:

Article

Progress in Clinical Pharmacology in China: An Ongoing Evolution.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 609, doi. 10.1002/cpt.3549

By:

Zhao, Liang;
van der Graaf, Piet H.

Publication type:

Article

Highlighted Articles.

Published in:: Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 612, doi. 10.1002/cpt.3548
Publication type:: Article

FDA Approval Summary: Nalmefene Nasal Spray for the Emergency Treatment of Known or Suspected Opioid Overdose.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 620, doi. 10.1002/cpt.3514

By:

Nallani, Srikanth C.;
Li, Zhihua;
Florian, Jeffry;
Xu, Yun;
Sabarinath, Sreedharan;
Brescia‐Oddo, Tanya;
Roca, Rigoberto A.;
Uppoor, Ramana S.;
Mehta, Mehul U.

Publication type:

Article

Assessment of Efficacy Evidence for Approvals of Novel Drugs in China Between 2018 and 2022.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 749, doi. 10.1002/cpt.3511

By:

Xu, Yang;
Li, Xinyu;
Guo, Qixiang;
Chen, Qi;
Su, Mengfan;
Zhang, Xuenong;
Yang, Yue

Publication type:

Article

ASCPT News.

Published in:: Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 614, doi. 10.1002/cpt.3551
Publication type:: Article

In This Issue.

Published in:: Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 607, doi. 10.1002/cpt.3550
Publication type:: Article

Oxygenation Effects of Antihypertensive Agents in Intensive Care: A Prospective Comparative Study of Nicardipine and Urapidil.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 742, doi. 10.1002/cpt.3509

By:

Suard, Florimond;
Mombrun, Martin;
Fischer, Marc‐Olivier;
Hanouz, Jean‐Luc;
Decros, Jean‐Baptiste;
Derville, Sébastien;
Gakuba, Clément;
Al Issa, Gulbhar;
Menard, Caroline;
Chretien, Basile;
Descamps, Richard

Publication type:

Article

Integrated Longitudinal Population Dose‐Hemoglobin Response of Daprodustat Following Dose Titration in Patients With Anemia in Chronic Kidney Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 846, doi. 10.1002/cpt.3544

By:

Mahar, Kelly M.;
van Noort, Martijn;
van den Berg, Paul;
Yang, Shuying;
Visser, Sandra A. G.;
Post, Teun M.

Publication type:

Article

Correction to "The Effect of Low‐Dose Colchicine on the Phenotype and Function of Neutrophils and Monocytes in Patients with Chronic Coronary Artery Disease: A Double‐Blind Randomized Placebo‐Controlled Cross‐over Study".

Published in:: Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 857, doi. 10.1002/cpt.3541
Publication type:: Article

Efficacy and Safety of Janus Kinase Inhibitors in Patients with Vitiligo: A Systematic Review and Meta‐Analysis.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 659, doi. 10.1002/cpt.3538

By:

Huang, Fan;
Hu, Dingyuan;
Fan, Huaying;
Hu, Binyi;
Liu, Yian;
Dong, Wenliang;
Liu, Xiangxing;
Li, Yanting;
Yan, Diqin;
Ding, Rui;
Niu, Suping;
Chen, Liming;
Nie, Xiaoyan;
Fang, Yi

Publication type:

Article

Impact of CYP2C19 Phenotype on Escitalopram Response in Geriatrics: Based on Physiologically‐Based Pharmacokinetic Modeling and Clinical Observation.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 826, doi. 10.1002/cpt.3537

By:

Jang, Yoo Jin;
Kim, Doh Kwan;
Lim, Shinn‐Won;
Hong, Eunjin

Publication type:

Article

Trends of Publication of Negative Trials Over Time.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 818, doi. 10.1002/cpt.3535

By:

Laviolle, Bruno;
Locher, Clara;
Allain, Jean‐Sébastien;
Le Cornu, Quentin;
Charpentier, Pierre;
Lefebvre, Marie;
Le Pape, Clémence;
Leven, Cyril;
Palpacuer, Clément;
Pontoizeau, Clémence;
Bellissant, Eric;
Naudet, Florian

Publication type:

Article

Prevalence Estimates of Cytochrome P450 Phenoconversion in Youth Receiving Pharmacotherapy for Mental Health Conditions.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 670, doi. 10.1002/cpt.3534

By:

Gerlach, Samuel;
Maruf, Abdullah Al;
Shaheen, Sarker M.;
McCloud, Ryden;
Heintz, Madison;
McAusland, Laina;
Arnold, Paul D.;
Bousman, Chad A.

Publication type:

Article

Toward Developing Alternative Opioid Antagonists for Treating Community Overdose: A Model‐Based Evaluation of Important Pharmacological Attributes.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 836, doi. 10.1002/cpt.3527

By:

Chaturbedi, Anik;
Mann, John;
Chakravartula, Shilpa;
Thrasher, Bradlee;
Arabidarrehdor, Ghazal;
Zirkle, Joel;
Meshkin, Hamed;
Nallani, Srikanth C.;
Florian, Jeffry;
Li, Zhihua

Publication type:

Article

Current Use of Physiologically Based Pharmacokinetic modeling in New Medicinal Product Approvals at EMA.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 808, doi. 10.1002/cpt.3525

By:

Paul, Polly;
Colin, Pieter J.;
Musuamba Tshinanu, Flora;
Versantvoort, Carolien;
Manolis, Efthymios;
Blake, Kevin

Publication type:

Article

Population Pharmacokinetic/Pharmacodynamic and Exposure‐Response Modeling Analyses of Sotatercept in Healthy Participants and Patients with Pulmonary Arterial Hypertension.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 798, doi. 10.1002/cpt.3524

By:

Ait‐Oudhia, Sihem;
Jaworowicz, David;
Hu, Ziheng;
Gaurav, Mitali;
Barcomb, Heather;
Hu, Shuai;
Bihorel, Sébastien;
Balasubrahmanyam, Budda;
Mistry, Bipin;
de Oliveira Pena, Janethe;
Wenning, Larissa;
Gheyas, Ferdous

Publication type:

Article

TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine‐1‐Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 787, doi. 10.1002/cpt.3521

By:

de Cuba, Catherine M. K. E.;
de Goede, Annika A.;
Klaassen, Erica S.;
Otto, Marije E.;
Doll, Robert J.;
Kim, Jessica;
Demitrack, Mark A.;
Chen, Ruihua;
Groeneveld, Geert Jan;
Heuberger, Jules A. A. C.

Publication type:

Article

Background Factors Contributing to Safety Warning Discordance in the Initial Labeling of New Drugs in Japan, the United States, and the European Union.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 779, doi. 10.1002/cpt.3518

By:

Fukuda, Koichi;
Narukawa, Mamoru

Publication type:

Article

Safety, Pharmacokinetics, and Pharmacodynamics of a First‐in‐Class ClC‐1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 768, doi. 10.1002/cpt.3516

By:

Ruijs, Titia Q.;
de Cuba, Catherine M. K. E.;
Heuberger, Jules A. A. C.;
Hutchison, John;
Bold, Jane;
Grønnebæk, Thomas S.;
Jensen, Klaus G.;
Chin, Eva;
Quiroz, Jorge A.;
Petersen, Thomas K.;
Flagstad, Peter;
de Kam, Marieke L.;
van Esdonk, Michiel J.;
Klaassen, Erica;
Doll, Robert J.;
Koopmans, Ingrid W.;
de Goede, Annika A.;
Aulin, Linda B. S.;
Pedersen, Thomas H.;
Groeneveld, Geert Jan

Publication type:

Article

Pharmacokinetics of the Monoclonal Antibody, Sotrovimab, in Healthy Participants Following IM Administration at Different Injection Sites.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 759, doi. 10.1002/cpt.3515

By:

El‐Zailik, Asma;
Sager, Jennifer;
Sánchez‐Pearson, Yasmin;
Parra, Sergio;
Moore, Jennifer;
Sarkar, Prosenjit;
Aylott, Alicia;
Wang, Qianwen;
Aldinger, Melissa;
Garner, Chad;
Mogalian, Erik;
Skingsley, Andrew;
Peppercorn, Amanda;
Reyes, Maribel

Publication type:

Article

Semimechanistic Population PK/PD Modeling of Axatilimab in Healthy Participants and Patients With Solid Tumors or Chronic Graft‐Versus‐Host Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 704, doi. 10.1002/cpt.3503

By:

Yang, Yan‐ou;
Sokolov, Victor;
Volkova, Alina;
Liu, Xing;
Leon, Cristina;
Kosinsky, Yuri;
Barker, Breann;
Zhang, Xuecheng;
Ordentlich, Peter;
Sheng, Jennifer;
Chen, Xuejun

Publication type:

Article

Clinical Actionability of the NUDT15 *4 (p.R139H) Allele and Its Association With Hispanic Ethnicity.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 724, doi. 10.1002/cpt.3501

By:

Maillard, Maud;
Nguyen, Jenny Q.;
Yang, Wenjian;
Hoshitsuki, Keito;
Relling, Mary V.;
Caudle, Kelly E.;
Crews, Kristine R.;
Jeha, Sima;
Inaba, Hiroto;
Pui, Ching‐Hon;
Bhatia, Smita;
Karol, Seth E.;
Antillon‐Klussmann, Federico G.;
Haidar, Cyrine E.;
Bhojwani, Deepa;
Yang, Jun J.

Publication type:

Article

Barriers and Facilitators for Bringing Model‐Informed Precision Dosing to the Patient's Bedside: A Systematic Review.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 633, doi. 10.1002/cpt.3510

By:

Dibbets, Anna Caroline;
Koldeweij, Charlotte;
Osinga, Esra P.;
Scheepers, Hubertina C. J.;
de Wildt, Saskia N.

Publication type:

Article

Planning and Implementing Master Protocol Trials in Japan: Key Considerations of the Japanese Guideline.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 627, doi. 10.1002/cpt.3508

By:

Hirakawa, Akihiro;
Asakawa, Takashi;
Tokushige, Kota;
Ozaki, Ryoto;
Yoshida, Mizuki;
Okuma, Hitomi Sumiyoshi;
Saito, Sho;
Shimizu, Yosuke;
Kitabayashi, Ryo;
Hanazawa, Ryoichi;
Sato, Hiroyuki;
Uemura, Yukari

Publication type:

Article

Clinical and Physiologically Based Pharmacokinetic Model Evaluations of Adagrasib Drug–Drug Interactions.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 732, doi. 10.1002/cpt.3506

By:

Cilliers, Cornelius;
Howgate, Eleanor;
Jones, Hannah M.;
Rahbaek, Lisa;
Tran, Jonathan Q.

Publication type:

Article

Mechanistic Modeling of Spatial Heterogeneity of Drug Penetration and Exposure in the Human Central Nervous System and Brain Tumors.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 690, doi. 10.1002/cpt.3505

By:

Li, Jing;
Wickramasinghe, Charuka;
Jiang, Jun;
Wu, Andrew;
Jiang, Yuanyuan;
Tovmasyan, Artak;
Kim, Seongho;
Sanai, Nader

Publication type:

Article

A Phase I Trial of the Pharmacokinetic Interaction Between Cannabidiol and Tacrolimus.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 716, doi. 10.1002/cpt.3504

By:

So, Gerald C.;
Lu, Jessica Bo Li;
Koyama, Sachiko;
Cheng, Ying‐Hua;
Gisch, Debora L.;
McClara, Kelsey;
Dexter, Paul R.;
Sharfuddin, Asif A.;
Etkins, Jumar;
Tillman, Emma M.;
Beamon, Travis R.;
Cowsert, Zachary;
Stuart, Jennifer S.;
Desta, Zeruesenay;
Eadon, Michael T.

Publication type:

Article

Distribution Characteristics and Impacting Factors of Drug CYP Enzymes and Transporters in the Gastrointestinal Tract of Chinese Healthy Subjects.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 676, doi. 10.1002/cpt.3497

By:

Zhang, Miao;
Zhang, Lei;
Suo, Baojun;
Wei, Yudong;
Xu, Yue;
Jiang, Muhan;
Dong, Jing;
Li, Xiaodong;
Song, Zhiqiang;
Liu, Dongyang

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 599, doi. 10.1002/cpt.3319
Publication type:: Article