Works matching IS 00099236 AND DT 2022 AND VI 111 AND IP 5

Results: 26

The Polymorphic Nuclear Factor NFIB Regulates Hepatic CYP2D6 Expression and Influences Risperidone Metabolism in Psychiatric Patients.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1165, doi. 10.1002/cpt.2571
By:
- Lenk, Hasan Çağın;
- Klöditz, Katharina;
- Johansson, Inger;
- Smith, Robert Løvsletten;
- Jukić, Marin M.;
- Molden, Espen;
- Ingelman‐Sundberg, Magnus
Publication type:
Article
In This Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 981, doi. 10.1002/cpt.2569
Publication type:
Article
Probability of Success in Drug Development.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 983, doi. 10.1002/cpt.2568
Publication type:
Article
ASCPT News.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 988, doi. 10.1002/cpt.2567
Publication type:
Article
Clinical and Molecular Profiling to Develop a Potential Prediction Model for the Response to Alemtuzumab Therapy for Acute Kidney Transplant Rejection.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1155, doi. 10.1002/cpt.2566
By:
- Hullegie‐Peelen, Daphne M.;
- van der Zwan, Marieke;
- Clahsen‐van Groningen, Marian C.;
- Mustafa, Dana A.M.;
- Baart, Sara J.;
- Reinders, Marlies E.J.;
- Baan, Carla C.;
- Hesselink, Dennis A.
Publication type:
Article
Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 986, doi. 10.1002/cpt.2562
Publication type:
Article
Leveraging Real‐World Data for EMA Qualification of a Model‐Based Biomarker Tool to Optimize Type‐1 Diabetes Prevention Studies.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1133, doi. 10.1002/cpt.2559
By:
- Podichetty, Jagdeep T.;
- Lang, Patrick;
- O'Doherty, Inish M.;
- David, Sarah E.;
- Muse, Rhoda N.;
- Karpen, Stephen R.;
- Song, Laura Sue;
- Romero, Klaus;
- Burton, Jackson K.
Publication type:
Article
Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1142, doi. 10.1002/cpt.2558
By:
- Wegler, Christine;
- Wiśniewski, Jacek R.;
- Robertsen, Ida;
- Christensen, Hege;
- Kristoffer Hertel, Jens;
- Hjelmesæth, Jøran;
- Jansson‐Löfmark, Rasmus;
- Åsberg, Anders;
- Andersson, Tommy B.;
- Artursson, Per
Publication type:
Article
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin‐Associated Musculoskeletal Symptoms.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1007, doi. 10.1002/cpt.2557
By:
- Cooper‐DeHoff, Rhonda M.;
- Niemi, Mikko;
- Ramsey, Laura B.;
- Luzum, Jasmine A.;
- Tarkiainen, E. Katriina;
- Straka, Robert J.;
- Gong, Li;
- Tuteja, Sony;
- Wilke, Russell A.;
- Wadelius, Mia;
- Larson, Eric A.;
- Roden, Dan M.;
- Klein, Teri E.;
- Yee, Sook Wah;
- Krauss, Ronald M.;
- Turner, Richard M.;
- Palaniappan, Latha;
- Gaedigk, Andrea;
- Giacomini, Kathleen M.;
- Caudle, Kelly E.
Publication type:
Article
The Central Role of pH in the Clinical Pharmacology of Nicotine: Implications for Abuse Liability, Cigarette Harm Reduction and FDA Regulation.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1004, doi. 10.1002/cpt.2555
Publication type:
Article
Association of CYP2C19 Polymorphism With Proton Pump Inhibitors Effectiveness and With Fractures in Real‐Life: Retrospective Cohort Study.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1084, doi. 10.1002/cpt.2552
By:
- Gronich, Naomi;
- lavi, Idit;
- Lejbkowicz, Flavio;
- Pinchev, Mila;
- Rennert, Gad
Publication type:
Article
Identification of Risk Factors for COVID‐19 Hospitalization in Patients With Anti‐Rheumatic Drugs: Results From a Multicenter Nested Case Control Study.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1061, doi. 10.1002/cpt.2551
By:
- Opdam, Merel A. A.;
- Benoy, Sophie;
- Verhoef, Lise M.;
- Van Bijnen, Sandra;
- Lamers‐Karnebeek, Femke;
- Traksel, René A. M.;
- Vos, Petra;
- den Broeder, Alfons A.;
- Broen, Jasper
Publication type:
Article
OX40L Inhibition Suppresses KLH‐driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof‐of‐Pharmacology for KY1005.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1121, doi. 10.1002/cpt.2539
By:
- Saghari, Mahdi;
- Gal, Pim;
- Gilbert, Sally;
- Yateman, Martin;
- Porter‐Brown, Ben;
- Brennan, Nuala;
- Quaratino, Sonia;
- Wilson, Rosamund;
- Grievink, Hendrika W.;
- Klaassen, Erica S.;
- Bergmann, Kirsten R.;
- Burggraaf, Jacobus;
- van Doorn, Martijn B. A.;
- Powell, John;
- Moerland, Matthijs;
- Rissmann, Robert
Publication type:
Article
The Impact of COVID‐19 on the Initiation of Clinical Trials in Europe and the United States.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1093, doi. 10.1002/cpt.2534
By:
- Lasch, Florian;
- Psarelli, Eftychia‐Eirini;
- Herold, Ralf;
- Mattsson, Andrea;
- Guizzaro, Lorenzo;
- Pétavy, Frank;
- Schiel, Anja
Publication type:
Article
Development of a Generic Physiologically‐Based Pharmacokinetic Model for Lactation and Prediction of Maternal and Infant Exposure to Ondansetron via Breast Milk.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1111, doi. 10.1002/cpt.2530
By:
- Job, Kathleen M.;
- Dallmann, André;
- Parry, Samuel;
- Saade, George;
- Haas, David M.;
- Hughes, Brenna;
- Berens, Pamela;
- Chen, Jia‐Yu;
- Fu, Christina;
- Humphrey, Kelsey;
- Hornik, Christoph;
- Balevic, Stephen;
- Zimmerman, Kanecia;
- Watt, Kevin
Publication type:
Article
The Pharmacoeconomic Benefits of Pemetrexed Dose Individualization in Patients With Lung Cancer.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1103, doi. 10.1002/cpt.2529
By:
- de Rouw, Nikki;
- de Boer, Merel;
- Boosman, René J.;
- van den Heuvel, Michel M.;
- Burger, David M.;
- Lieverse, Joris E.;
- Derijks, Hieronymus J.;
- Frederix, Geert W.J.;
- ter Heine, Rob
Publication type:
Article
SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1075, doi. 10.1002/cpt.2527
By:
- Voora, Deepak;
- Baye, Jordan;
- McDermaid, Adam;
- Narayana Gowda, Smitha;
- Wilke, Russell A.;
- Nicole Myrmoe, Anna;
- Hajek, Catherine;
- Larson, Eric A.
Publication type:
Article
Probability of Success: A Crucial Concept to Inform Decision Making in Pharmaceutical Research and Development.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1001, doi. 10.1002/cpt.2513
By:
- Lalonde, Richard L.;
- Peck, Carl C.
Publication type:
Article
The pH of Smokeless Tobacco Determines Nicotine Buccal Absorption: Results of a Randomized Crossover Trial.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1066, doi. 10.1002/cpt.2493
By:
- Wilhelm, Jess;
- Mishina, Elena;
- Viray, Lauren;
- Paredes, Antonio;
- Pickworth, Wallace B.
Publication type:
Article
Mechanistic Basis for Maximally Efficacious Dose of Pembrolizumab.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 994, doi. 10.1002/cpt.2492
By:
- Mayawala, Kapil;
- Nayak, Tapan;
- Jain, Lokesh;
- de Alwis, Dinesh
Publication type:
Article
Dose Optimization of Pembrolizumab: Less May Be More.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 993, doi. 10.1002/cpt.2490
By:
- Ratain, Mark J.;
- Peer, Cody J.;
- Figg, William D.;
- Goldstein, Daniel A.
Publication type:
Article
A New Comprehensive Approach to Assess the Probability of Success of Development Programs Before Pivotal Trials.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1050, doi. 10.1002/cpt.2488
By:
- Hampson, Lisa V.;
- Holzhauer, Björn;
- Bornkamp, Björn;
- Kahn, Joseph;
- Lange, Markus R.;
- Luo, Wen‐Lin;
- Singh, Pritibha;
- Ballerstedt, Steffen;
- Cioppa, Giovanni Della
Publication type:
Article
Physiologically‐Based Pharmacokinetic Modeling to Support Determination of Bioequivalence for Dermatological Drug Products: Scientific and Regulatory Considerations.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1036, doi. 10.1002/cpt.2356
By:
- Tsakalozou, Eleftheria;
- Alam, Khondoker;
- Babiskin, Andrew;
- Zhao, Liang
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 973, doi. 10.1002/cpt.2296
Publication type:
Article
Heterogeneity in COVID‐19 Convalescent Plasma Clinical Trials.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 995, doi. 10.1002/cpt.2281
By:
- Müller‐Olling, Mirco;
- Vahlensieck, Ute;
- Hilger, Anneliese
Publication type:
Article
Can In Vitro–In Vivo Extrapolation Be Successful? Recognizing the Incorrect Clearance Assumptions.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1022, doi. 10.1002/cpt.2482
By:
- Benet, Leslie Z.;
- Sodhi, Jasleen K.
Publication type:
Article