Works matching IS 00099236 AND DT 2021 AND VI 109 AND IP 5

Results: 30

ASCPT News.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1175, doi. 10.1002/cpt.2232
Publication type:
Article
Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1173, doi. 10.1002/cpt.2231
Publication type:
Article
Real‐World Evidence and the Regulation of Medicines.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1169, doi. 10.1002/cpt.2230
By:
- Honig, Peter K.
Publication type:
Article
In This Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1167, doi. 10.1002/cpt.2229
Publication type:
Article
Defining Clinically Relevant Target Populations Using Real‐World Data to Guide the Design of Representative Antidiabetic Drug Trials.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1219, doi. 10.1002/cpt.2213
By:
- Pradhan, Richeek;
- Abrahami, Devin;
- Yin, Hui;
- Yu, Oriana H.Y.;
- Sahasrabudhe, Vaishali;
- Baumfeld Andre, Elodie;
- Azoulay, Laurent
Publication type:
Article
A New Era in Pharmacovigilance: Toward Real‐World Data and Digital Monitoring.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1197, doi. 10.1002/cpt.2172
By:
- Lavertu, Adam;
- Vora, Bianca;
- Giacomini, Kathleen M.;
- Altman, Russ;
- Rensi, Stefano
Publication type:
Article
Drug‐Drug Interaction Surveillance Study: Comparing Self‐Controlled Designs in Five Empirical Examples in Real‐World Data.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1353, doi. 10.1002/cpt.2119
By:
- Bykov, Katsiaryna;
- Li, Hu;
- Kim, Sangmi;
- Vine, Seanna M.;
- Lo Re, Vincent;
- Gagne, Joshua J.
Publication type:
Article
CORRIGENDUM: Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1362, doi. 10.1002/cpt.2116
Publication type:
Article
Depletion of LAG‐3<sup>+</sup> T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1293, doi. 10.1002/cpt.2091
By:
- Ellis, Joanne;
- J.B. Marks, Daniel;
- Srinivasan, Naren;
- Barrett, Christine;
- Hopkins, Thomas G.;
- Richards, Anna;
- Fuhr, Rainard;
- Albayaty, Muna;
- Coenen, Martin;
- Liefaard, Lia;
- Leavens, Karen;
- Nevin, Katherine L.;
- Tang, Shuo;
- Hughes, Stephen A.;
- Fortunato, Léa;
- Edwards, Ken;
- Cui, Yi;
- Anselm, Rabia;
- Delves, Christopher J.;
- Charles, Emilie
Publication type:
Article
Organic Anion Transporting Polypeptide Inhibition Dramatically Increases Plasma Exposure but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure of Firsocostat.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1334, doi. 10.1002/cpt.2105
By:
- Kirby, Brian J.;
- Lutz, Justin D.;
- Yue, Mun Sang;
- Garrison, Kimberly L.;
- Qin, Ann Ran‐Ran;
- Ampaw, Lorraine;
- Beysen, Carine;
- Myers, Robert P.;
- Kearney, Brian P.;
- Mathias, Anita
Publication type:
Article
Pharmacology‐Guided Rule‐Based Adaptive Dose Escalation in First‐in‐Human Studies.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1326, doi. 10.1002/cpt.2101
By:
- Hoogdalem, Ewoud‐Jan;
- Iersel, Mattheus (Thijs);
- Winter, Erica;
- Constant, John;
- Kappler, Martin
Publication type:
Article
Population Pharmacokinetics of Trastuzumab Deruxtecan in Patients With HER2‐Positive Breast Cancer and Other Solid Tumors.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1314, doi. 10.1002/cpt.2096
By:
- Yin, Ophelia;
- Xiong, Yuan;
- Endo, Seiko;
- Yoshihara, Kazutaka;
- Garimella, Tushar;
- AbuTarif, Malaz;
- Wada, Russ;
- LaCreta, Frank
Publication type:
Article
Effects of Protein and Calorie Restriction on the Metabolism and Toxicity Profile of Irinotecan in Cancer Patients.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1304, doi. 10.1002/cpt.2094
By:
- Man, Femke M.;
- Eerden, Ruben A.G.;
- Doorn, Gerdien M.;
- Oomen‐de Hoop, Esther;
- Koolen, Stijn L.W.;
- Olieman, Joanne F.;
- Bruijn, Peter;
- Veraart, Joris N.;
- Halteren, Henk K.;
- Sandberg, Yorick;
- Moelker, Adriaan;
- IJzermans, Jan N.M.;
- Lolkema, Martijn P.;
- Gelder, Teun;
- Dollé, Martijn E.T.;
- Bruin, Ron W.F.;
- Mathijssen, Ron H.J.
Publication type:
Article
Assessing Transporter‐Mediated Natural Product‐Drug Interactions Via In vitro‐In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1342, doi. 10.1002/cpt.2107
By:
- Nguyen, James T.;
- Tian, Dan‐Dan;
- Tanna, Rakshit S.;
- Hadi, Deena L.;
- Bansal, Sumit;
- Calamia, Justina C.;
- Arian, Christopher M.;
- Shireman, Laura M.;
- Molnár, Bálint;
- Horváth, Miklós;
- Kellogg, Joshua J.;
- Layton, Matthew E.;
- White, John R.;
- Cech, Nadja B.;
- Boyce, Richard D.;
- Unadkat, Jashvant D.;
- Thummel, Kenneth E.;
- Paine, Mary F.
Publication type:
Article
Real‐World Comparative Effectiveness and Safety of Non‐Vitamin K Antagonist Oral Anticoagulants vs. Warfarin in a Developing Country.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1282, doi. 10.1002/cpt.2090
By:
- Mitsuntisuk, Phatcharin;
- Nathisuwan, Surakit;
- Junpanichjaroen, Athirat;
- Wongcharoen, Wanwarang;
- Phrommintikul, Arintaya;
- Wattanaruengchai, Phannita;
- Rattanavipanon, Wipharak;
- Chulavatnatol, Suvatna;
- Chaiyakunapruk, Nathorn;
- Likittanasombat, Khanchit;
- Lip, Gregory Y. H.
Publication type:
Article
Randomized Controlled Trials Versus Real World Evidence: Neither Magic Nor Myth.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1212, doi. 10.1002/cpt.2083
By:
- Eichler, Hans‐Georg;
- Pignatti, Francesco;
- Schwarzer‐Daum, Brigitte;
- Hidalgo‐Simon, Ana;
- Eichler, Irmgard;
- Arlett, Peter;
- Humphreys, Anthony;
- Vamvakas, Spiros;
- Brun, Nikolai;
- Rasi, Guido
Publication type:
Article
Inosine 5'‐Monophosphate to Raise Serum Uric Acid Level in Multiple System Atrophy (IMPROVE‐MSA study).
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1274, doi. 10.1002/cpt.2082
By:
- Jung Lee, Jae;
- Han Yoon, Jung;
- Jin Kim, Sang;
- Soo Yoo, Han;
- Jong Chung, Seok;
- Hyun Lee, Yang;
- Yun Kang, Suk;
- Shin, Hae‐Won;
- Keun Song, Sook;
- Yong Hong, Jin;
- Sunwoo, MunKyung;
- Eun Lee, Ji;
- Sam Baik, Jong;
- Sohn, Young H.;
- Hyu Lee, Phil
Publication type:
Article
Evolving Landscape of New Drug Approval in Japan and Lags from International Birth Dates: Retrospective Regulatory Analysis.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1265, doi. 10.1002/cpt.2080
By:
- Tanaka, Mototsugu;
- Idei, Mayumi;
- Sakaguchi, Hiroshi;
- Kato, Ryosuke;
- Sato, Daisuke;
- Sawanobori, Kenji;
- Kawarasaki, Shuichi;
- Hata, Toshiyuki;
- Yoshizaki, Asako;
- Nakamura, Miki;
- Ikuma, Mutsuhiro
Publication type:
Article
Tri‐Allelic Haplotypes Determine and Differentiate Functionally Normal Allele CYP2D6*2 and Impaired Allele CYP2D6*41.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1256, doi. 10.1002/cpt.2078
By:
- Zanger, Ulrich M.;
- Momoi, Kyoko;
- Hofmann, Ute;
- Schwab, Matthias;
- Klein, Kathrin
Publication type:
Article
Model‐Based Quantification of Impact of Genetic Polymorphisms and Co‐Medications on Pharmacokinetics of Tamoxifen and Six Metabolites in Breast Cancer.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1244, doi. 10.1002/cpt.2077
By:
- Puszkiel, Alicja;
- Arellano, Cécile;
- Vachoux, Christelle;
- Evrard, Alexandre;
- Le Morvan, Valérie;
- Boyer, Jean‐Christophe;
- Robert, Jacques;
- Delmas, Caroline;
- Dalenc, Florence;
- Debled, Marc;
- Venat‐Bouvet, Laurence;
- Jacot, William;
- Dohollou, Nadine;
- Bernard‐Marty, Chantal;
- Laharie‐Mineur, Hortense;
- Filleron, Thomas;
- Roché, Henri;
- Chatelut, Etienne;
- Thomas, Fabienne;
- White‐Koning, Melanie
Publication type:
Article
Regarding Combined Pediatric and Adult Trials Submitted to the US Food and Drug Administration 2012–2018.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1181, doi. 10.1002/cpt.2076
By:
- Cook, Jack;
- Weiner, Dan;
- Powell, J. Robert
Publication type:
Article
CORRIGENDUM: Tribute: Marcus M. Reidenberg, MD.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1361, doi. 10.1002/cpt.2075
Publication type:
Article
Target Adverse Event Profiles for Predictive Safety in the Postmarket Setting.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1232, doi. 10.1002/cpt.2074
By:
- Schotland, Peter;
- Racz, Rebecca;
- Jackson, David B.;
- Soldatos, Theodoros G.;
- Levin, Robert;
- Strauss, David G.;
- Burkhart, Keith
Publication type:
Article
Cannabidiol and Abnormal Liver Chemistries in Healthy Adults: Results of a Phase I Clinical Trial.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1224, doi. 10.1002/cpt.2071
By:
- Watkins, Paul B.;
- Church, Rachel J.;
- Li, Jie;
- Knappertz, Volker
Publication type:
Article
Clopidogrel Dosing: Current Successes and Emerging Factors for Further Consideration.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1203, doi. 10.1002/cpt.2055
By:
- Chetty, Manoranjenni;
- Ravenstijn, Paulien;
- Manchandani, Pooja
Publication type:
Article
The Certainty Framework for Assessing Real‐World Data in Studies of Medical Product Safety and Effectiveness.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1189, doi. 10.1002/cpt.2045
By:
- Cocoros, Noelle M.;
- Arlett, Peter;
- Dreyer, Nancy A.;
- Ishiguro, Chieko;
- Iyasu, Solomon;
- Sturkenboom, Miriam;
- Zhou, Wei;
- Toh, Sengwee
Publication type:
Article
Balancing Safety and Efficacy With Early Availability in the Regulation of Regenerative Medicine Product.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1182, doi. 10.1002/cpt.2034
By:
- Fujiwara, Yasuhiro;
- Maruyama, Yoshiaki;
- Honda, Futaba
Publication type:
Article
Possible Role of ABCB1 in Lysosomal Accumulation of Azithromycin in COVID‐19 Therapy.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1180, doi. 10.1002/cpt.2020
By:
- Scherrmann, Jean‐Michel
Publication type:
Article
3D Spheroids of Primary Human Hepatocytes: An In Vitro Model That Will Make Pharmacotherapy Safer?
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1186, doi. 10.1002/cpt.2019
By:
- Pavek, Petr
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 5, p. 1159, doi. 10.1002/cpt.1899
Publication type:
Article