Works matching IS 00099236 AND DT 2021 AND VI 109 AND IP 4

Results: 39

Clinical Pharmacology‐Informed Development of COVID‐19 Therapeutics: Regulatory Experience.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 810, doi. 10.1002/cpt.2210
By:
- Choi, Su‐Young;
- Arya, Vikram;
- Reynolds, Kellie
Publication type:
Article
In This Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 791, doi. 10.1002/cpt.2209
Publication type:
Article
The Complex Roadmap to Infectious Disease Innovation: The Intersection of Bugs, Drugs, and Special Populations.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 793, doi. 10.1002/cpt.2208
By:
- Nicol, Melanie R.;
- Cicali, Emily J.;
- Seo, Shirley K.;
- Rao, Gauri G.
Publication type:
Article
Vaccines: Underlying Principles of Design and Testing.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 987, doi. 10.1002/cpt.2207
By:
- Kallon, Sallay;
- Samir, Shahryar;
- Goonetilleke, Nilu
Publication type:
Article
ASCPT News.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 799, doi. 10.1002/cpt.2206
Publication type:
Article
Combating Multidrug‐Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1000, doi. 10.1002/cpt.2205
By:
- Lang, Yinzhi;
- Shah, Nirav R.;
- Tao, Xun;
- Reeve, Stephanie M.;
- Zhou, Jieqiang;
- Moya, Bartolome;
- Sayed, Alaa R. M.;
- Dharuman, Suresh;
- Oyer, Jeremiah L.;
- Copik, Alicja J.;
- Fleischer, Brett A.;
- Shin, Eunjeong;
- Werkman, Carolin;
- Basso, Kari B.;
- Deveson Lucas, Deanna;
- Sutaria, Dhruvitkumar S.;
- Mégroz, Marianne;
- Kim, Tae Hwan;
- Loudon‐Hossler, Victoria;
- Wright, Amy
Publication type:
Article
Highlights: April.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 797, doi. 10.1002/cpt.2204
Publication type:
Article
From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 928, doi. 10.1002/cpt.2202
By:
- Wicha, Sebastian G.;
- Märtson, Anne‐Grete;
- Nielsen, Elisabet I.;
- Koch, Birgit C.P.;
- Friberg, Lena E.;
- Alffenaar, Jan‐Willem;
- Minichmayr, Iris K.
Publication type:
Article
Key Challenges in Providing Effective Antibiotic Therapy for Critically Ill Patients with Bacterial Sepsis and Septic Shock.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 892, doi. 10.1002/cpt.2203
By:
- Landersdorfer, Cornelia B.;
- Nation, Roger L.
Publication type:
Article
Anti‐Infective Dosing in Special Populations: Pregnancy.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 977, doi. 10.1002/cpt.2192
By:
- Hazenberg, Phoebe;
- Navaratnam, Kate;
- Busuulwa, Paula;
- Waitt, Catriona
Publication type:
Article
Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 867, doi. 10.1002/cpt.2198
By:
- Rayner, Craig R.;
- Smith, Patrick F.;
- Andes, David;
- Andrews, Kayla;
- Derendorf, Hartmut;
- Friberg, Lena E.;
- Hanna, Debra;
- Lepak, Alex;
- Mills, Edward;
- Polasek, Thomas M.;
- Roberts, Jason A.;
- Schuck, Virna;
- Shelton, Mark J.;
- Wesche, David;
- Rowland‐Yeo, Karen
Publication type:
Article
Evaluation Strategies for Triple‐Drug Combinations against Carbapenemase‐Producing Klebsiella Pneumoniae in an In Vitro Hollow‐Fiber Infection Model.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1074, doi. 10.1002/cpt.2197
By:
- Garcia, Estefany;
- Diep, John K.;
- Sharma, Rajnikant;
- Hanafin, Patrick O.;
- Abboud, Cely S.;
- Kaye, Keith S.;
- Li, Jian;
- Velkov, Tony;
- Rao, Gauri G.
Publication type:
Article
Neglecting Plasma Protein Binding in COVID‐19 Patients Leads to a Wrong Interpretation of Lopinavir Overexposure.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1030, doi. 10.1002/cpt.2196
By:
- Stanke‐Labesque, Francoise;
- Concordet, Didier;
- Djerada, Zoubir;
- Bouchet, Stéphane;
- Solas, Caroline;
- Mériglier, Etienne;
- Bonnet, Fabrice;
- Mourvillier, Bruno;
- Ruiz, Stéphanie;
- Martin‐Blondel, Guillaume;
- Epaulard, Olivier;
- Schwebel, Carole;
- Gautier‐Veyret, Elodie;
- Gandia, Peggy
Publication type:
Article
Tribute to Professor Hartmut Derendorf ‐ 1953 to 2020: Driving force in Clinical Pharmacology and Mentor Extraordinaire.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 805, doi. 10.1002/cpt.2193
By:
- Johnson, Julie A.;
- Schmidt, Stephan
Publication type:
Article
Antimicrobial Dose Selection under the Animal Rule.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 971, doi. 10.1002/cpt.2201
By:
- Wu, Kunyi;
- Choi, Su‐Young;
- Bergman, Kimberly;
- Seo, Shirley
Publication type:
Article
Evaluation of Meropenem‐Ciprofloxacin Combination Dosage Regimens for the Pharmacokinetics of Critically Ill Patients With Augmented Renal Clearance.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1104, doi. 10.1002/cpt.2191
By:
- Agyeman, Akosua A.;
- Rogers, Kate E.;
- Tait, Jessica R.;
- Bergen, Phillip J.;
- Kirkpatrick, Carl M.;
- Wallis, Steven C.;
- Bulitta, Jürgen B.;
- Paterson, David L.;
- Lipman, Jeffrey;
- Nation, Roger L.;
- Roberts, Jason A.;
- Landersdorfer, Cornelia B.
Publication type:
Article
Too Much of a Good Thing: Defining Antimicrobial Therapeutic Targets to Minimize Toxicity.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 905, doi. 10.1002/cpt.2190
By:
- Downes, Kevin J.;
- Goldman, Jennifer L.
Publication type:
Article
Pharmacology of HIV Cure: Site of Action.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 841, doi. 10.1002/cpt.2187
By:
- Devanathan, Aaron S.;
- Cottrell, Mackenzie L.
Publication type:
Article
The Lymph Node Reservoir: Physiology, HIV Infection, and Antiretroviral Therapy.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 918, doi. 10.1002/cpt.2186
By:
- Scholz, Erin M. B.;
- Kashuba, Angela D. M.
Publication type:
Article
Real‐World Evidence for Assessing Pharmaceutical Treatments in the Context of COVID‐19.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 816, doi. 10.1002/cpt.2185
By:
- Franklin, Jessica M.;
- Lin, Kueiyu Joshua;
- Gatto, Nicolle M.;
- Rassen, Jeremy A.;
- Glynn, Robert J.;
- Schneeweiss, Sebastian
Publication type:
Article
How Semiphysiological Population Pharmacokinetic Modeling Incorporating Active Hepatic Uptake Supports Phase II Dose Selection of RO7049389, A Novel Anti–Hepatitis B Virus Drug.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1081, doi. 10.1002/cpt.2184
By:
- Cosson, Valérie;
- Feng, Sheng;
- Jaminion, Felix;
- Lemenuel‐Diot, Annabelle;
- Parrott, Neil;
- Paehler, Axel;
- Bo, Qingyan;
- Jin, Yuyan
Publication type:
Article
Antimicrobial Dosing in Specific Populations and Novel Clinical Methodologies: Obesity.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 942, doi. 10.1002/cpt.2181
By:
- Pai, Manjunath P.
Publication type:
Article
Pivotal Role of Translation in Anti‐Infective Development.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 856, doi. 10.1002/cpt.2182
By:
- Friberg, Lena E.
Publication type:
Article
Variation in Target Attainment of Beta‐Lactam Antibiotic Dosing Between International Pediatric Formularies.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 958, doi. 10.1002/cpt.2180
By:
- Gastine, Silke;
- Hsia, Yingfen;
- Clements, Michelle;
- Barker, Charlotte I.S.;
- Bielicki, Julia;
- Hartmann, Christine;
- Sharland, Mike;
- Standing, Joseph F.
Publication type:
Article
Antimicrobial Dosing in Specific Populations and Novel Clinical Methodologies: Kidney Function.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 952, doi. 10.1002/cpt.2179
By:
- Pai, Manjunath P.
Publication type:
Article
Physiologically‐Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1025, doi. 10.1002/cpt.2178
By:
- Stader, Felix;
- Courlet, Perrine;
- Decosterd, Laurent A.;
- Battegay, Manuel;
- Marzolini, Catia
Publication type:
Article
RAAS Blockade and COVID‐19: Mechanistic Modeling of Mas and AT1 Receptor Occupancy as Indicators of Pro‐Inflammatory and Anti‐Inflammatory Balance.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1092, doi. 10.1002/cpt.2177
By:
- Melissa Hallow, Karen;
- Dave, Ishaan
Publication type:
Article
Physiologically‐Based Pharmacokinetic Modeling of Remdesivir and Its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients With COVID‐19.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1116, doi. 10.1002/cpt.2176
By:
- Lutz, Justin D.;
- Mathias, Anita;
- German, Polina;
- Pikora, Cheryl;
- Reddy, Sunila;
- Kirby, Brian J.
Publication type:
Article
FDA's Limited Population Pathway for Antibacterial and Antifungal Drugs.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 813, doi. 10.1002/cpt.2175
By:
- Nambiar, Sumathi;
- Walinsky, Sarah;
- Schumann, Katherine
Publication type:
Article
Mechanistic Modeling of SARS‐CoV‐2 and Other Infectious Diseases and the Effects of Therapeutics.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 829, doi. 10.1002/cpt.2160
By:
- Perelson, Alan S.;
- Ke, Ruian
Publication type:
Article
Remdesivir and Acute Renal Failure: A Potential Safety Signal From Disproportionality Analysis of the WHO Safety Database.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1021, doi. 10.1002/cpt.2145
By:
- Gérard, Alexandre O.;
- Laurain, Audrey;
- Fresse, Audrey;
- Parassol, Nadège;
- Muzzone, Marine;
- Rocher, Fanny;
- Esnault, Vincent L.M.;
- Drici, Milou‐Daniel
Publication type:
Article
Clinical Characteristics and Outcome of Drug‐Induced Liver Injury in the Older Patients: From the Young‐Old to the Oldest‐Old.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1147, doi. 10.1002/cpt.2108
By:
- Weersink, Rianne A.;
- Alvarez‐Alvarez, Ismael;
- Medina‐Cáliz, Inmaculada;
- Sanabria‐Cabrera, Judith;
- Robles‐Díaz, Mercedes;
- Ortega‐Alonso, Aida;
- García‐Cortés, Miren;
- Bonilla, Elvira;
- Niu, Hao;
- Soriano, German;
- Jimenez‐Perez, Miguel;
- Hallal, Hacibe;
- Blanco, Sonia;
- Kaplowitz, Neil;
- Lucena, M. Isabel;
- Andrade, Raúl J.;
- Andrade, R.J.;
- Lucena, M.I.;
- Stephens, C.;
- García Cortés, M.
Publication type:
Article
Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1063, doi. 10.1002/cpt.2104
By:
- Sou, Tomás;
- Hansen, Jon;
- Liepinsh, Edgars;
- Backlund, Maria;
- Ercan, Onur;
- Grinberga, Solveiga;
- Cao, Sha;
- Giachou, Paraskevi;
- Petersson, Anna;
- Tomczak, Magdalena;
- Urbas, Malgorzata;
- Zabicka, Dorota;
- Vingsbo Lundberg, Carina;
- Hughes, Diarmaid;
- Hobbie, Sven N.;
- Friberg, Lena E.
Publication type:
Article
Genetic Risk Factors in Drug‐Induced Liver Injury Due to Isoniazid‐Containing Antituberculosis Drug Regimens.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1125, doi. 10.1002/cpt.2100
By:
- Nicoletti, Paola;
- Devarbhavi, Harshad;
- Goel, Ashish;
- Venkatesan, Radha;
- Eapen, Chundamannil E.;
- Grove, Jane I.;
- Zafer, Samreen;
- Bjornsson, Einar;
- Lucena, M. Isabel;
- Andrade, Raul J.;
- Pirmohamed, Munir;
- Wadelius, Mia;
- Larrey, Dominique;
- Maitland‐van der Zee, Anke‐Hilse;
- Ibanez, Luisa;
- Watkins, Paul B;
- Daly, Ann K.;
- Aithal, Guruprasad P.
Publication type:
Article
Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1136, doi. 10.1002/cpt.2097
By:
- Al‐Majdoub, Zubida M.;
- Couto, Narciso;
- Achour, Brahim;
- Harwood, Matthew D.;
- Carlson, Gordon;
- Warhurst, Geoffrey;
- Barber, Jill;
- Rostami‐Hodjegan, Amin
Publication type:
Article
Pharmacokinetics and Drug‐Drug Interactions of Isoniazid and Efavirenz in Pregnant Women Living With HIV in High TB Incidence Settings: Importance of Genotyping.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1034, doi. 10.1002/cpt.2044
By:
- Gausi, Kamunkhwala;
- Wiesner, Lubbe;
- Norman, Jennifer;
- Wallis, Carole L.;
- Onyango‐Makumbi, Carolyne;
- Chipato, Tsungai;
- Haas, David W.;
- Browning, Renee;
- Chakhtoura, Nahida;
- Montepiedra, Grace;
- Aaron, Lisa;
- McCarthy, Katie;
- Bradford, Sarah;
- Vhembo, Tichaona;
- Stranix‐Chibanda, Lynda;
- Masheto, Gaerolwe R.;
- Violari, Avy;
- Mmbaga, Blandina T.;
- Aurpibul, Linda;
- Bhosale, Ramesh
Publication type:
Article
Cannabidivarin for HIV‐Associated Neuropathic Pain: A Randomized, Blinded, Controlled Clinical Trial.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1055, doi. 10.1002/cpt.2016
By:
- Eibach, Luca;
- Scheffel, Simone;
- Cardebring, Madeleine;
- Lettau, Marie;
- Özgür Celik, M.;
- Morguet, Andreas;
- Roehle, Robert;
- Stein, Christoph
Publication type:
Article
Modeling the Effect of DAV132, a Novel Colon‐Targeted Adsorbent, on Fecal Concentrations of Moxifloxacin and Gut Microbiota Diversity in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1045, doi. 10.1002/cpt.1977
By:
- Guk, Jinju;
- Guedj, Jérémie;
- Burdet, Charles;
- Andremont, Antoine;
- Gunzburg, Jean;
- Ducher, Annie;
- Mentré, France
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 783, doi. 10.1002/cpt.1898
Publication type:
Article