Works matching IS 00099236 AND DT 2021 AND VI 109 AND IP 1

Results: 34

ASCPT News January.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 17, doi. 10.1002/cpt.2115
By:
- Laffman‐Johnson, Elise
Publication type:
Article
Roger W. Jelliffe, MD, FCP, FAAPS: A World Leader in Population Pharmacokinetic and Pharmacodynamic Modeling and Model‐Based Target Controlled Individualized Dosing.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 22, doi. 10.1002/cpt.2114
By:
- Neely, Michael N.;
- Vinks, Alexander A.
Publication type:
Article
Evaluation of a Pilot Vancomycin Precision Dosing Advisory Service on Target Exposure Attainment Using an Interrupted Time Series Analysis.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 212, doi. 10.1002/cpt.2113
By:
- Stocker, Sophie L.;
- Carland, Jane E.;
- Reuter, Stephanie E.;
- Stacy, Alexandra E.;
- Schaffer, Andrea L.;
- Stefani, Maurizio;
- Lau, Cindy;
- Kirubakaran, Ranita;
- Yang, Jennifer J.;
- Shen, Catriona F.J.;
- Roberts, Darren M.;
- Marriott, Deborah J.E.;
- Day, Richard O.;
- Brett, Jonathan
Publication type:
Article
Precision Dosing: The Clinical Pharmacology of Goldilocks.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 11, doi. 10.1002/cpt.2112
By:
- Peck, Richard W.;
- Shahin, Mohamed H.;
- Vinks, Alexander A.
Publication type:
Article
Physiologically Based Precision Dosing Approach for Drug‐Drug‐Gene Interactions: A Simvastatin Network Analysis.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 201, doi. 10.1002/cpt.2111
By:
- Wojtyniak, Jan‐Georg;
- Selzer, Dominik;
- Schwab, Matthias;
- Lehr, Thorsten
Publication type:
Article
In this Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 9, doi. 10.1002/cpt.2110
Publication type:
Article
Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 222, doi. 10.1002/cpt.2102
By:
- Achour, Brahim;
- Al‐Majdoub, Zubida M.;
- Grybos‐Gajniak, Agnieszka;
- Lea, Kristi;
- Kilford, Peter;
- Zhang, Mian;
- Knight, David;
- Barber, Jill;
- Schageman, Jeoffrey;
- Rostami‐Hodjegan, Amin
Publication type:
Article
Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 15, doi. 10.1002/cpt.2109
Publication type:
Article
Model‐Based Approach to Improve Clinical Outcomes in Neonates With Opioid Withdrawal Syndrome Using Real‐World Data.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 243, doi. 10.1002/cpt.2093
By:
- Wijekoon, Nadeesri;
- Aduroja, Oluwatobi;
- Biggs, Jessica M.;
- El‐Metwally, Dina;
- Gopalakrishnan, Mathangi
Publication type:
Article
Physiologically‐Based Pharmacokinetic Models as Enablers of Precision Dosing in Drug Development: Pivotal Role of the Human Mass Balance Study.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 51, doi. 10.1002/cpt.2092
By:
- Rowland Yeo, Karen;
- Venkatakrishnan, Karthik
Publication type:
Article
Continuous Learning in Model‐Informed Precision Dosing: A Case Study in Pediatric Dosing of Vancomycin.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 233, doi. 10.1002/cpt.2088
By:
- Hughes, Jasmine H.;
- Tong, Dominic M. H.;
- Lucas, Sarah Scarpace;
- Faldasz, Jonathan D.;
- Goswami, Srijib;
- Keizer, Ron J.
Publication type:
Article
Quantitative Benefit–Risk Assessment of P‐gp–Mediated Drug–Drug Interactions of Dabigatran Coadministered With Pharmacokinetic Enhancers in Patients With Renal Impairment.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 193, doi. 10.1002/cpt.2087
By:
- Lingineni, Karthik;
- Farhan, Nashid;
- Kim, Sarah;
- Cristofoletti, Rodrigo;
- Gordon, Lori A.;
- Kumar, Parag;
- Penzak, Scott;
- Hadigan, Colleen;
- George, Jomy M.;
- Brown, Joshua D.;
- Schmidt, Stephan
Publication type:
Article
A Tutorial for Pharmacogenomics Implementation Through End‐to‐End Clinical Decision Support Based on Ten Years of Experience from PREDICT.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 101, doi. 10.1002/cpt.2079
By:
- Liu, Michelle;
- Vnencak‐Jones, Cindy L.;
- Roland, Bartholomew P.;
- Gatto, Cheryl L.;
- Mathe, Janos L.;
- Just, Shari L.;
- Peterson, Josh F.;
- Van Driest, Sara L.;
- Weitkamp, Asli O.
Publication type:
Article
A Systematic Assessment of US Food and Drug Administration Dosing Recommendations For Drug Development Programs Amenable to Response‐Guided Titration.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 123, doi. 10.1002/cpt.2068
By:
- Wang, Lingshan;
- Maxfield, Kimberly;
- Guinn, Daphne;
- Madabushi, Rajanikanth;
- Zineh, Issam;
- Schuck, Robert N.
Publication type:
Article
PharmGKB Tutorial for Pharmacogenomics of Drugs Potentially Used in the Context of COVID‐19.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 116, doi. 10.1002/cpt.2067
By:
- Huddart, Rachel;
- Whirl‐Carrillo, Michelle;
- Altman, Russ B.;
- Klein, Teri E.
Publication type:
Article
A Model Averaging/Selection Approach Improves the Predictive Performance of Model‐Informed Precision Dosing: Vancomycin as a Case Study.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 175, doi. 10.1002/cpt.2065
By:
- Uster, David W.;
- Stocker, Sophie L.;
- Carland, Jane E.;
- Brett, Jonathan;
- Marriott, Deborah J.E.;
- Day, Richard O.;
- Wicha, Sebastian G.
Publication type:
Article
Precision Dosing: An Industry Perspective.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 47, doi. 10.1002/cpt.2064
By:
- Peck, Richard W.
Publication type:
Article
Supporting Precision Dosing in Drug Labeling.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 37, doi. 10.1002/cpt.2054
By:
- Neely, Michael;
- Onufrak, Nikolas;
- Scheetz, Marc H.;
- Avedissian, Sean;
- Lakota, Elizabeth;
- Deitchman, Amelia N.;
- Gonzalez, Daniel
Publication type:
Article
Perspectives on Model‐Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 29, doi. 10.1002/cpt.2049
By:
- Kluwe, Franziska;
- Michelet, Robin;
- Mueller‐Schoell, Anna;
- Maier, Corinna;
- Klopp‐Schulze, Lena;
- Dyk, Madelé;
- Mikus, Gerd;
- Huisinga, Wilhelm;
- Kloft, Charlotte
Publication type:
Article
Extrapolating Pharmacodynamic Effects From Adults to Pediatrics: A Case Study of Ustekinumab in Pediatric Patients With Moderate to Severe Plaque Psoriasis.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 131, doi. 10.1002/cpt.2033
By:
- Zhou, Wangda;
- Hu, Chuanpu;
- Zhu, Yaowei;
- Randazzo, Bruce;
- Song, Michael;
- Sharma, Amarnath;
- Xu, Zhenhua;
- Zhou, Honghui
Publication type:
Article
Changing the Clinical Paradigm of Hydroxyurea Treatment for Sickle Cell Anemia Through Precision Medicine.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 73, doi. 10.1002/cpt.2028
By:
- Dong, Min;
- McGann, Patrick T.
Publication type:
Article
Model Informed Development of VRC01 in Newborn Infants Using a Population Pharmacokinetics Approach.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 184, doi. 10.1002/cpt.2026
By:
- Li, Jerry;
- Nikanjam, Mina;
- Cunningham, Coleen K.;
- McFarland, Elizabeth J.;
- Coates, Emily E.;
- Houser, Katherine V.;
- Lin, Bob C.;
- McDermott, Adrian B.;
- Flach, Britta;
- Gama, Lucio;
- Koup, Richard A.;
- Graham, Barney S.;
- Mascola, John R.;
- Ledgerwood, Julie E.;
- Capparelli, Edmund V.
Publication type:
Article
Creatinine‐Based Renal Function Assessment in Pediatric Drug Development: An Analysis Using Clinical Data for Renally Eliminated Drugs.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 263, doi. 10.1002/cpt.1991
By:
- Zhang, Yifei;
- Sherwin, Catherine M.;
- Gonzalez, Daniel;
- Zhang, Qunshu;
- Khurana, Mona;
- Fisher, Jeffrey;
- Burckart, Gilbert J.;
- Wang, Yaning;
- Yao, Lynne P.;
- Ganley, Charles J.;
- Wang, Jian
Publication type:
Article
Physiologically‐Based Pharmacokinetic Modeling Characterizes the CYP3A‐Mediated Drug‐Drug Interaction Between Fluconazole and Sildenafil in Infants.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 253, doi. 10.1002/cpt.1990
By:
- Salerno, Sara N.;
- Edginton, Andrea;
- Gerhart, Jacqueline G.;
- Laughon, Matthew M.;
- Ambalavanan, Namasivayam;
- Sokol, Gregory M.;
- Hornik, Chi D.;
- Stewart, Dan;
- Mills, Mary;
- Martz, Karen;
- Gonzalez, Daniel;
- Benjamin Jr, Daniel K;
- Hornik, Christoph;
- Zimmerman, Kanecia;
- Kennel, Phyllis;
- Beci, Rose;
- Hornik, Chi Dang;
- Kearns, Gregory L;
- Laughon, Matthew;
- Paul, Ian M
Publication type:
Article
Regulatory Efforts to Facilitate Evaluation and Clinical Management of Drug‐Drug Interaction Risks.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 42, doi. 10.1002/cpt.1984
By:
- Yang, Xinning;
- Pfuma Fletcher, Elimika;
- Huang, Shiew‐Mei;
- Zineh, Issam;
- Madabushi, Rajanikanth
Publication type:
Article
Quantification of In Vivo Metabolic Activity of CYP2D6 Genotypes and Alleles Through Population Pharmacokinetic Analysis of Vortioxetine.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 150, doi. 10.1002/cpt.1972
By:
- Frederiksen, Trine;
- Areberg, Johan;
- Schmidt, Ellen;
- Bjerregaard Stage, Tore;
- Brøsen, Kim
Publication type:
Article
From Real‐World Patient Data to Individualized Treatment Effects Using Machine Learning: Current and Future Methods to Address Underlying Challenges.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 87, doi. 10.1002/cpt.1907
By:
- Bica, Ioana;
- Alaa, Ahmed M.;
- Lambert, Craig;
- Schaar, Mihaela
Publication type:
Article
Proceedings of a Workshop: Precision Dosing: Defining the Need and Approaches to Deliver Individualized Drug Dosing in the Real‐World Setting.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 25, doi. 10.1002/cpt.1933
By:
- Maxfield, Kimberly;
- Milligan, Lauren;
- Wang, Lingshan;
- Gonzalez, Daniel;
- Johnson‐Williams, Bernadette;
- Liu, Qi;
- Madabushi, Rajanikanth;
- Powell, Robert;
- Wang, Yaning;
- Zhu, Hao;
- Zineh, Issam
Publication type:
Article
Drug Dosing Recommendations for All Patients: A Roadmap for Change.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 65, doi. 10.1002/cpt.1923
By:
- Powell, J. Robert;
- Cook, Jack;
- Wang, Yaning;
- Peck, Richard;
- Weiner, Dan
Publication type:
Article
Interpretation of Cytochrome P‐450 Inhibition and Induction Effects From Clinical Data: Current Standards and Recommendations for Implementation.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 82, doi. 10.1002/cpt.1918
By:
- Stout, Stephen M.;
- Nemerovski, Carrie W.;
- Streetman, Daniel S.;
- Berg, Melody;
- Hoffman, Jamie;
- Burke, Kayann;
- Bemben, Nina M.;
- Sklar, Stephen J.
Publication type:
Article
Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 55, doi. 10.1002/cpt.1916
By:
- Zamek‐Gliszczynski, Maciej J.;
- Patel, Mitesh;
- Yang, Xinning;
- Lutz, Justin D.;
- Chu, Xiaoyan;
- Brouwer, Kim L. R.;
- Lai, Yurong;
- Lee, Caroline A.;
- Neuhoff, Sibylle;
- Paine, Mary F.;
- Sugiyama, Yuichi;
- Taskar, Kunal S.;
- Galetin, Aleksandra
Publication type:
Article
Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost‐Effectiveness of Preemptive Pharmacogenetic Testing.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 160, doi. 10.1002/cpt.1944
By:
- Zhou, Yitian;
- Krebs, Kristi;
- Milani, Lili;
- Lauschke, Volker M.
Publication type:
Article
The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 140, doi. 10.1002/cpt.1890
By:
- Groen, Bianca D.;
- Krekels, Elke H. J.;
- Mooij, Miriam G.;
- Duijn, Esther;
- Vaes, Wouter H. J.;
- Windhorst, Albert D.;
- Rosmalen, Joost;
- Hartman, Stan J. F.;
- Hendrikse, N. Harry;
- Koch, Birgit C. P.;
- Allegaert, Karel;
- Tibboel, Dick;
- Knibbe, Catherijne A. J.;
- Wildt, Saskia N.
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 1, doi. 10.1002/cpt.1895
Publication type:
Article