Works matching IS 00099236 AND DT 2014 AND VI 95
Results: 147
Aspirin Decreases Systemic Exposure to Clopidogrel Through Modulation of P-Glycoprotein But Does Not Alter Its Antithrombotic Activity.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 608, doi. 10.1038/clpt.2014.49
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A Resource for Facilitating the Development of Tools in the Education and Implementation of Genomics-Informed Personalized Medicine.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 590, doi. 10.1038/clpt.2014.39
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Ivacaftor Therapy in the Context of CFTR Genotype.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 592, doi. 10.1038/clpt.2014.54
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Highlights.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 572, doi. 10.1038/clpt.2014.80
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Methods for Measuring, Enhancing, and Accounting for Medication Adherence in Clinical Trials.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 617, doi. 10.1038/clpt.2014.59
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Misinterpretation of TPMT by a DTC Genetic Testing Company.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 598, doi. 10.1038/clpt.2014.60
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In This Issue.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 565, doi. 10.1038/clpt.2014.81
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Should Pharmacometrics Be Training the Next R&D President?
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 579, doi. 10.1038/clpt.2014.68
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Pacemaker Current Inhibition in Experimental Human Cardiac Sympathetic Activation: A Double-Blind, Randomized, Crossover Study.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 601, doi. 10.1038/clpt.2014.25
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Whither Pharmacometrics?: Present State and Future Choices.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 567, doi. 10.1038/clpt.2014.72
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Response to 'The Effect of Green Tea With Exceptionally High Catechin Content on Nadolol Plasma Concentration'.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 589, doi. 10.1038/clpt.2014.61
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Integrating Systems Biology Sources Illuminates Drug Action.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 663, doi. 10.1038/clpt.2014.51
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CYP2C9, SLCO1B1, SLCO1B3, and ABCB11 Polymorphisms in Patients With Bosentan-Induced Liver Toxicity.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 583, doi. 10.1038/clpt.2014.42
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ASCPT News.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 574, doi. 10.1038/clpt.2014.73
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- Article
The Effect of Green Tea With Exceptionally High Catechin Content on Nadolol Plasma Concentration.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 588, doi. 10.1038/clpt.2014.36
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Fluoxetine- and Norfluoxetine-Mediated Complex Drug-Drug Interactions: In Vitro to In Vivo Correlation of Effects on CYP2D6, CYP2C19, and CYP3A4.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 653, doi. 10.1038/clpt.2014.50
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Genetic Risk Factors for Major Bleeding in Patients Treated With Warfarin in a Community Setting.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 636, doi. 10.1038/clpt.2014.26
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Drug Resistance of a Viral Population and Its Individual Intrahost Variants During the First 48 Hours of Therapy.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 627, doi. 10.1038/clpt.2014.20
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Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 644, doi. 10.1038/clpt.2014.37
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Clopidogrel for Smokers and Aspirin for Nonsmokers?: Not So Fast.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 585, doi. 10.1038/clpt.2014.52
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The ISoP Standards and Best Practices Committee.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 6, p. 581, doi. 10.1038/clpt.2014.65
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Recent Trends and Success Factors in Reducing the Lag Time to Approval of New Drugs in Japan.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 467, doi. 10.1038/clpt.2013.256
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Drug Development in Serious Diseases: The New 'Breakthrough Therapy' Designation.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 483, doi. 10.1038/clpt.2014.23
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The FDA's Role in the Development of Medical Mobile Applications.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 485, doi. 10.1038/clpt.2014.45
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Advances in Inhaled Technologies: Understanding the Therapeutic Challenge, Predicting Clinical Performance, and Designing the Optimal Inhaled Product.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 509, doi. 10.1038/clpt.2014.27
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Improving the Assessment of Heart Toxicity for All New Drugs Through Translational Regulatory Science.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 501, doi. 10.1038/clpt.2013.238
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Mobile Medical Applications: Old Wine in New Bottles?
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 476, doi. 10.1038/clpt.2014.35
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In This Issue.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 453, doi. 10.1038/clpt.2014.58
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The Biotechnology Innovation Machine: A Source of Intelligent Biopharmaceuticals for the Pharma Industry-Mapping Biotechnology's Success.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 528, doi. 10.1038/clpt.2014.14
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ASCPT News.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 462, doi. 10.1038/clpt.2014.53
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Significant Differences in Drug Lag in Clinical Development Among Various Strategies Used for Regulatory Submissions in Japan.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 533, doi. 10.1038/clpt.2013.223
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Exposure-Response Relationship of T-DM1: Insight Into Dose Optimization for Patients With HER2-Positive Metastatic Breast Cancer.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 558, doi. 10.1038/clpt.2014.24
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Modeling and Simulation of Biopharmaceutical Performance.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 480, doi. 10.1038/clpt.2014.40
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Itraconazole and Clarithromycin as Ketoconazole Alternatives for Clinical CYP3A Inhibition Studies.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 473, doi. 10.1038/clpt.2014.41
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PBPK Model Describes the Effects of Comedication and Genetic Polymorphism on Systemic Exposure of Drugs That Undergo Multiple Clearance Pathways.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 550, doi. 10.1038/clpt.2014.43
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The Role of Academic Medical Centers in Advancing Regulatory Science.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 471, doi. 10.1038/clpt.2014.33
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Assessment of Factors Associated With Dose Differences Between Japan and the United States.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 542, doi. 10.1038/clpt.2013.231
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Physiologically Based Pharmacokinetic Modeling: From Regulatory Science to Regulatory Policy.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 478, doi. 10.1038/clpt.2014.46
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Response to 'Can CYP3A Activity Be Evaluated for Drug Interaction Using a Nanogram Dose of Probe Drug?': Evaluation of CYP3A Activity With Microdoses of Midazolam.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 490, doi. 10.1038/clpt.2014.28
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The Role of Big Data and Advanced Analytics in Drug Discovery, Development, and Commercialization.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 492, doi. 10.1038/clpt.2014.29
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The Paradox of Scientific Excellence and the Search for Productivity in Pharmaceutical Research and Development.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 521, doi. 10.1038/clpt.2013.242
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Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 Update.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 499, doi. 10.1038/clpt.2014.38
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Promise and Challenges With the Use of Mobile Applications to Support and Improve Patient Care: An Industry Perspective.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 469, doi. 10.1038/clpt.2014.34
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Exploring the FDA Adverse Event Reporting System to Generate Hypotheses for Monitoring of Disease Characteristics.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 496, doi. 10.1038/clpt.2014.17
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Can CYP3A Activity Be Evaluated for Drug Interaction Using a Nanogram Dose of Probe Drug?
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 489, doi. 10.1038/clpt.2014.6
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Highlights.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 460, doi. 10.1038/clpt.2014.57
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Intelligent Pharmaceuticals: Beyond the Tipping Point.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 5, p. 455, doi. 10.1038/clpt.2014.32
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Adaptive Reprogramming of the Breast Cancer Kinome.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 4, p. 413, doi. 10.1038/clpt.2014.8
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Green Tea Ingestion Greatly Reduces Plasma Concentrations of Nadolol in Healthy Subjects.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 4, p. 432, doi. 10.1038/clpt.2013.241
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Identification and Characterization of a Defective CYP3A4 Genotype in a Kidney Transplant Patient With Severely Diminished Tacrolimus Clearance.
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- Clinical Pharmacology & Therapeutics, 2014, v. 95, n. 4, p. 416, doi. 10.1038/clpt.2013.210
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