Works matching IS 00099236 AND DT 2012 AND VI 92 AND IP 2

Results: 23

Rare Diseases: The Bane of Modern Society and the Quest for Cures.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 135, doi. 10.1038/clpt.2012.97
By:
- Azie, N;
- Vincent, J
Publication type:
Article
Raising Orphans: How Clinical Development Programs of Drugs for Rare and Common Diseases Are Different.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 262, doi. 10.1038/clpt.2012.87
By:
- Orfali, M;
- Feldman, L;
- Bhattacharjee, V;
- Harkins, P;
- Kadam, S;
- Lo, C;
- Ravi, M;
- Shringarpure, D T;
- Mardekian, J;
- Cassino, C;
- Coté, T
Publication type:
Article
Detection of Pharmacovigilance-Related Adverse Events Using Electronic Health Records and Automated Methods.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 228, doi. 10.1038/clpt.2012.54
By:
- Haerian, K;
- Varn, D;
- Vaidya, S;
- Ena, L;
- Chase, H S;
- Friedman, C
Publication type:
Article
Quantitative Analysis to Guide Orphan Drug Development.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 258, doi. 10.1038/clpt.2012.80
By:
- Lesko, L J
Publication type:
Article
The Future of Orphan Drug Development.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 146, doi. 10.1038/clpt.2012.89
By:
- Woodcock, J
Publication type:
Article
The Challenges of Orphan Drugs and Orphan Diseases: Real and Imagined.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 151, doi. 10.1038/clpt.2012.72
By:
- Hudson, I;
- Breckenridge, A
Publication type:
Article
Equivalent Dynamic Human Brain NK1-Receptor Occupancy Following Single-Dose i.v. Fosaprepitant vs. Oral Aprepitant as Assessed by PET Imaging.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 243, doi. 10.1038/clpt.2012.62
By:
- Van Laere, K;
- De Hoon, J;
- Bormans, G;
- Koole, M;
- Derdelinckx, I;
- De Lepeleire, I;
- Declercq, R;
- Sanabria Bohorquez, S M;
- Hamill, T;
- Mozley, P D;
- Tatosian, D;
- Xie, W;
- Liu, Y;
- Liu, F;
- Zappacosta, P;
- Mahon, C;
- Butterfield, K L;
- Rosen, L B;
- Murphy, M G;
- Hargreaves, R J
Publication type:
Article
Drug Absorption Interactions Between Oral Targeted Anticancer Agents and PPIs: Is pH-Dependent Solubility the Achilles Heel of Targeted Therapy?
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 203, doi. 10.1038/clpt.2012.73
By:
- Budha, N R;
- Frymoyer, A;
- Smelick, G S;
- Jin, J Y;
- Yago, M R;
- Dresser, M J;
- Holden, S N;
- Benet, L Z;
- Ware, J A
Publication type:
Article
Time-Varying Belatacept Exposure and Its Relationship to Efficacy/Safety Responses in Kidney-Transplant Recipients.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 251, doi. 10.1038/clpt.2012.84
By:
- Zhou, Z;
- Shen, J;
- Hong, Y;
- Kaul, S;
- Pfister, M;
- Roy, A
Publication type:
Article
Off-Label Use of Medicines: Time for Action.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 157, doi. 10.1038/clpt.2012.74
By:
- Gnjidic, D;
- Le Couteur, D G;
- Hilmer, S N
Publication type:
Article
ASCPT News.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 142, doi. 10.1038/clpt.2012.91
Publication type:
Article
Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 140, doi. 10.1038/clpt.2012.104
Publication type:
Article
The Effects of Heparins on the Liver: Application of Mechanistic Serum Biomarkers in a Randomized Study in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 214, doi. 10.1038/clpt.2012.40
By:
- Harrill, A H;
- Roach, J;
- Fier, I;
- Eaddy, J S;
- Kurtz, C L;
- Antoine, D J;
- Spencer, D M;
- Kishimoto, T K;
- Pisetsky, D S;
- Park, B K;
- Watkins, P B
Publication type:
Article
In This Issue.
Published in:
2012
Publication type:
Table of Contents
LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 158, doi. 10.1038/clpt.2012.58
By:
- Zambrowicz, B;
- Freiman, J;
- Brown, P M;
- Frazier, K S;
- Turnage, A;
- Bronner, J;
- Ruff, D;
- Shadoan, M;
- Banks, P;
- Mseeh, F;
- Rawlins, D B;
- Goodwin, N C;
- Mabon, R;
- Harrison, B A;
- Wilson, A;
- Sands, A;
- Powell, D R
Publication type:
Article
UGT1A4*3 Encodes Significantly Increased Glucuronidation of Olanzapine in Patients on Maintenance Treatment and in Recombinant Systems.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 221, doi. 10.1038/clpt.2012.46
By:
- Haslemo, T;
- Loryan, I;
- Ueda, N;
- Mannheimer, B;
- Bertilsson, L;
- Ingelman-Sundberg, M;
- Molden, E;
- Eliasson, E
Publication type:
Article
The Role of Academic Institutions in the Development of Drugs for Rare and Neglected Diseases.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 193, doi. 10.1038/clpt.2012.83
By:
- Coles, L D;
- Cloyd, J C
Publication type:
Article
Neglected Infections of Poverty in Texas and the Rest of the United States: Management and Treatment Options.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 170, doi. 10.1038/clpt.2012.85
By:
- Barry, M A;
- Bezek, S;
- Serpa, J A;
- Hotez, P J;
- Woc-Colburn, L
Publication type:
Article
The Current State of Therapeutic Drug Trials in Pregnancy.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 149, doi. 10.1038/clpt.2012.81
By:
- Endicott, S;
- Haas, D M
Publication type:
Article
Gene, Stem Cell, and Future Therapies for Orphan Diseases.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 182, doi. 10.1038/clpt.2012.82
By:
- Phillips, M Ian
Publication type:
Article
Optimizing Drug Outcomes Through Pharmacogenetics: A Case for Preemptive Genotyping.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 235, doi. 10.1038/clpt.2012.66
By:
- Schildcrout, J S;
- Denny, J C;
- Bowton, E;
- Gregg, W;
- Pulley, J M;
- Basford, M A;
- Cowan, J D;
- Xu, H;
- Ramirez, A H;
- Crawford, D C;
- Ritchie, M D;
- Peterson, J F;
- Masys, D R;
- Wilke, R A;
- Roden, D M
Publication type:
Article
Ethical Considerations in Orphan Drug Approval and Use.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 153, doi. 10.1038/clpt.2012.92
By:
- Kesselheim, A S
Publication type:
Article
Modeling Helps in Understanding Antidepressants.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 2, p. 155, doi. 10.1038/clpt.2012.88
By:
- Holford, N
Publication type:
Article