Works in Clinical Pharmacology & Therapeutics, 2004, Vol 75, Issue 2

Results: 366

The pediatric module at the coordination center for clinical trials heidelberg-an approach to improve quality and conduct of clinical drug trials in children.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P24, doi. 10.1016/j.clpt.2003.11.090

By:

Ebert, U.;
Feneberg, R.;
Toenshoff, B.;
Seibert-Grafe, M.

Publication type:

Article

Pregvit: an alternate prenatal supplement for women with nausea and vomiting in pregnancy.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P25, doi. 10.1016/j.clpt.2003.11.093

By:

Ahn, E.;
Kapur, B.;
Einarson, A.;
Koren, G.

Publication type:

Article

Steady state pharmacokinetic study of FLAGYL® ER in pregnant patients during the second to third trimester of pregnancy.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P24, doi. 10.1016/j.clpt.2003.11.091

By:

Stika, C.;
Andrews, W.;
Frederiksen, M.;
Mercer, B.;
Sibai, B.;
Antal, E.

Publication type:

Article

Ontogeny of renal P-glycoprotein expression in mice: implications for pediatric dosing*.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P25, doi. 10.1016/j.clpt.2003.11.092

By:

Pinto, N.;
Halachmi, N.;
Woodland, C.;
Koren, G.

Publication type:

Article

The transfer of glyburide into breast milk*.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P24, doi. 10.1016/j.clpt.2003.11.089

By:

Feig, D. S.;
Kraemer, J. M.;
Moskovitz, D. N.;
Donat, D.;
Koren, G.

Publication type:

Article

Fluvoxamine (LUVOX™) use in pregnancy.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P25, doi. 10.1016/j.clpt.2003.11.094

By:

Sivojelezova, A.

Publication type:

Article

The use of fatty acid ethyl esters in neonatal hair to identify infants affected by prenatal alcohol exposure: a baseline study.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P25, doi. 10.1016/j.clpt.2003.11.095

By:

Caprara, D. L.;
Klein, J.;
Koren, G.

Publication type:

Article

Increased reactive oxygen stress in cells of patients with drug hypersensitivity.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P26, doi. 10.1016/j.clpt.2003.11.096

By:

Rieder, M. J.;
Cukernik, V.;
Oakes, G.;
Bend, J.

Publication type:

Article

Triangular test (TT), a sequential approach for comparative trials in children.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P26, doi. 10.1016/j.clpt.2003.11.098

By:

Pons, G.;
Hulot, J.;
Treluyer, J.;
Chiron, C.;
Tonnelier, S.;
Lechat, P.

Publication type:

Article

Absence of circadian variation in the pharmacokinetics (PK) of lopinavir/ritonavir (LPV/R) in a once-daily (QD) dosing regimen in HIV-1-infected subjects.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P35, doi. 10.1016/j.clpt.2003.11.133

By:

van Heeswijk, R.;
Bourbeau, M.;
Seguin, I.;
Cote, D.;
Giguere, P.;
Garber, G.;
Cameron, B.

Publication type:

Article

ASsessment of botanical supplementation on human cytochrome P450 phenotype: citrus aurantium, echinacea, milk thistle, saw palmetto.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P35, doi. 10.1016/j.clpt.2003.11.134

By:

Gurley, B. J.;
Gardner, S. F.;
Hubbard, M. A.;
Williams, K.;
Gentry, B.;
Carrier, J.;
Edwards, D.;
Khan, I.

Publication type:

Article

Torsades des Pointe (TDP) associated with methadone maintenance therapy (MMT) in a patient with hepatitis-induced cirrhosis.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P45, doi. 10.1016/j.clpt.2003.11.167

By:

Tiyyagura, S. R.;
Waldman, S. A.;
Kraft, W. K.

Publication type:

Article

Time-dependent toxicity of sulfonamide reactive metabolites in cells of patients with sulfonamide hypersensitivity.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P26, doi. 10.1016/j.clpt.2003.11.097

By:

Cukernik, V.;
Rieder, M. J.

Publication type:

Article

Over-the-counter vitamin K1-Containing multivitamin supplements disrupt oral anticoagulation in susceptible patients-a prospective trial.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P27, doi. 10.1016/j.clpt.2003.11.100

By:

Kurnik, D.;
Rabinovitz, H.;
Loebstein, R.;
Austerweil, N.;
Almog, S.;
Halkin, H.

Publication type:

Article

Pharmacokinetics (PK) and pharmacodynamics (PD) of enfuvirtide in hiv-1 infected adolescents over 24 weeks of treatment.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P26, doi. 10.1016/j.clpt.2003.11.099

By:

Zhang, X.;
Dorr, A.;
Siddique, Z.;
Bertasso, A.;
Rowell, L.;
Kolis, S.

Publication type:

Article

A double blind comparison of the opiate antagonist, naltrexone and promethazine in the prophylaxis or palliation of chloroquine induced pruritus in malaria fever.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P27, doi. 10.1016/j.clpt.2003.11.101

By:

Ajayi, A.;
Kolawole, B. A.

Publication type:

Article

Are brand-name and generic warfarin interchangeable?

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P27, doi. 10.1016/j.clpt.2003.11.103

By:

Pereira, J. A.;
Holbrook, A. M.;
Dolovich, L.;
Douketis, J. D.;
Crowther, M. A.;
Bates, S. M.;
Ginsberg, J. R.;
Goldsmith, C.;
Thabane, L.

Publication type:

Article

Plasma and cerebrospinal fluid (CSF) pharmacokinetics of CP-457,920, a selective alpha 5 GABA-A receptor inverse agonist in young, healthy volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P30, doi. 10.1016/j.clpt.2003.11.115

By:

Bednar, M.;
Chieffo, C.;
Morse, T.;
Duplin, M.;
Gibbs, M. A.

Publication type:

Article

Natural health product use in Canada: patterns of use and the risk of interactions with pharmaceuticals.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P28, doi. 10.1016/j.clpt.2003.11.104

By:

Singh, S. R.;
Levine, M.

Publication type:

Article

Geographic variation in indicators of opiate abuse and treatment availability in California.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P28, doi. 10.1016/j.clpt.2003.11.105

By:

Mendelson, J. E.;
Lodhia, N.

Publication type:

Article

Effect of fluvastatin on CYP2C9 activity using warfarin as a probe.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P28, doi. 10.1016/j.clpt.2003.11.106

By:

Kim, M.;
Nafziger, A. N.;
Kirchheiner, J.;
Bauer, S.;
Gaedigk, A.;
Bertino, J. S.

Publication type:

Article

Dose-dependent pharmacokinetics (PK) of short IV infusions of selodenoson (DTI-0009), a novel adenosine (A1-) receptor agonist, in healthy subjects.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P28, doi. 10.1016/j.clpt.2003.11.107

By:

Venitz, J.;
Men, A. Y.;
Townsend, R. W.;
Dessimoz, M.

Publication type:

Article

Decreased bioavailability of rifampicin and other anti-tb drugs in patients with advanced HIV disease.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P29, doi. 10.1016/j.clpt.2003.11.108

By:

Gurumurthy, P.;
Ramachandran, G.;
Hemanthkumar, A.;
Rajasekaran, S.;
Padmapriyadarsini, C.;
Swaminathan, S.;
Bhagavathy, S.;
Venkatesan, P.;
Sekar, L.;
Mahilmaran, A.;
Ravichandran, N.;
Paramesh, P.

Publication type:

Article

Effect of multiple doses of fenofibrate on the pharmacokinetics of pravastatin.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P29, doi. 10.1016/j.clpt.2003.11.109

By:

Gustavson, L. E.;
Schweitzer, S. M.;
Koehne-Voss, S.;
Achari, R.;
Chira, T.;
Esslinger, H.;
Yannicelli, H. D.

Publication type:

Article

Interaction between grapefruit juice and hypnotic drugs: comparison of triazolam and quazepam.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P29, doi. 10.1016/j.clpt.2003.11.110

By:

Fujimura, A.;
Sugimoto, K.;
Araki, N.;
Ohmori, M.;
Cui, Y.;
Tsuruoka, S.;
Kawaguchi, A.

Publication type:

Article

Population pharmacokinetics analysis of patients receiving enoxaparin by continuous intravenous infusion.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P30, doi. 10.1016/j.clpt.2003.11.112

By:

Feng, Y.;
Bies, R. R.;
Bobek, M. B.;
Kane, S. L.

Publication type:

Article

Accurate vs. approximate likelihood methods in population analysis of sparse data sets.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P30, doi. 10.1016/j.clpt.2003.11.113

By:

Leary, R. H.;
Jelliffe, R.;
Schumitzky, A.;
Port, R. E.

Publication type:

Article

Evaluate human PK prediction of compound LY based on allometric scaling with three species.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P30, doi. 10.1016/j.clpt.2003.11.114

By:

Mu, S.;
Anderson, S.;
Mahadevan, S.

Publication type:

Article

Oral clotrimazole (CLZ) decreases presystemic metabolism of cytochrome P450 (CYP) 3A4 substrates.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P31, doi. 10.1016/j.clpt.2003.11.117

By:

Shord, S. S.;
Chan, L.;
Camp, J. R.;
Vasquez, E.;
Baum, C.;
Molokie, R. E.

Publication type:

Article

The contraceptive vaginal ring, nuvaring, shows no interaction with broad spectrum oral antibiotics.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P33, doi. 10.1016/j.clpt.2003.11.124

By:

Dogterom, P.;
van den Heuvel, M.;
Thomsen, T.

Publication type:

Article

Population pharmacokinetics (POPPK) of valproic acid (VPA) following rapid infusion in epilepsy patients.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P31, doi. 10.1016/j.clpt.2003.11.116

By:

Dutta, S.;
Cloyd, J. C.

Publication type:

Article

Celecoxib pharmacokinetics in pediatric cancer patients-The effects of food and pharmacogenetics*.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P31, doi. 10.1016/j.clpt.2003.11.118

By:

Stempak, D. C.;
Bukaveckas, B. L.;
Linder, M. W.;
Koren, G.;
Baruchel, S.

Publication type:

Article

Clinical pharmacology of tezosentan, a dual endothelin receptor antagonist, in patients with liver cirrhosis.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P31, doi. 10.1016/j.clpt.2003.11.119

By:

Dingemanse, J.;
Halabi, A.;
Hoever, P.;
Chadha-Boreham, H.;
van Giersbergen, P. L.

Publication type:

Article

The safety, tolerability and pharmacodynamic responses of interferon BETA-1A (Rebif®) versus interferon BETA-1B (Betaseron®) in healthy male volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P32, doi. 10.1016/j.clpt.2003.11.120

By:

Gariepy, S.;
Marier, J.;
Potvin, D.;
Di Marco, M.;
Byrnes, W.;
Abdul-Ahad, A.

Publication type:

Article

Nelfinavir (NFV) population pharmacokinetics (PK) in long-term suppressors compared with the pk of the new 625 mg formulation in healthy volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P32, doi. 10.1016/j.clpt.2003.11.121

By:

Capparelli, E.;
Goebel, F. D.;
Williams, I.;
Opravil, M.;
Nelson, M.;
Daniels, E.;
Pun, E.;
Hsyu, P.

Publication type:

Article

Pharmacokinetics of single and multiple escalating doses of dapoxetine in healthy volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P32, doi. 10.1016/j.clpt.2003.11.123

By:

Dresser, M.;
Lindert, K.;
Lin, D.;
Gidwani, S.;
Gupta, S. K.;
Modi, N. B.

Publication type:

Article

Nonlinear mixed effects model analysis of the pharmacokinetics of metoprolol in middle-aged and elderly Japanese patients.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P32, doi. 10.1016/j.clpt.2003.11.122

By:

Taguchi, M.;
Nozawa, T.;
Mizumaki, K.;
Inoue, H.;
Tahara, K.;
Takesono, C.;
Hashimoto, Y.

Publication type:

Article

An open-label study on the pharmacokinetics (PK) of pitavastatin (NK-104) when administered concomitantly with fenofibrate or gemfibrozil in healthy volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P33, doi. 10.1016/j.clpt.2003.11.125

By:

Mathew, P.;
Cuddy, T.;
Tracewell, W. G.;
Salazar, D.

Publication type:

Article

Effect of rofecoxib, etoricoxib, celecoxib, and naproxen on urinary excretion of prostanoids in elderly volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P34, doi. 10.1016/j.clpt.2003.11.127

By:

Schwartz, J. I.;
Vandormael, K.;
Thach, C.;
Lasseter, K. C.;
Holmes, G. B.;
Miller, J. L.;
Hreniuk, D.;
Hilliard, D.;
Snyder, K. M.;
Gertz, B. J.;
Gottesdiener, K. M.

Publication type:

Article

Pharmacokinetic (PK) interaction study of sirolimus (SRL) and cyclosporine (CSA).

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P33, doi. 10.1016/j.clpt.2003.11.126

By:

Patat, A.;
Zimmerman, J. J.;
Parks, V.;
Richards, J.

Publication type:

Article

Initial antipyrine disposition in man is altered by propranolol.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P34, doi. 10.1016/j.clpt.2003.11.128

By:

Avram, M. J.;
Henthorn, T. K.;
Niemann, C. U.;
Shanks, C. A.;
Krejcie, T. C.

Publication type:

Article

Effect of rifampin on the pharmacokinetics of rosiglitazone in korean healthy subjects.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P34, doi. 10.1016/j.clpt.2003.11.129

By:

Park, J.;
Kim, K.;
Jung, W.;
Kim, S.;
Shin, J.

Publication type:

Article

Assessment of biliary excretion in humans using a novel oroenteric tube*.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P35, doi. 10.1016/j.clpt.2003.11.132

By:

Johnson, B. M.;
Ghibellini, G.;
Heizer, W. D.;
Brouwer, K. L.

Publication type:

Article

Pharmacokinetics (PK) of intraveneous scopolamine (SCP) plus physostigmine (PHY) in healthy elderly male and female volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P34, doi. 10.1016/j.clpt.2003.11.130

By:

Men, A.;
Venitz, J.

Publication type:

Article

Renal function and albumin concentration are determinants of mycophenolic acid pharmacokinetics.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P35, doi. 10.1016/j.clpt.2003.11.131

By:

van Hest, R. M.;
van Gelder, T.;
Vulto, A. G.;
Mathot, R. A.

Publication type:

Article

Effect of CYP3A-inhibitor and -inducer on the pharmacokinetics of intravenous midazolam in CYP3A5*3 allele carriers.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P38, doi. 10.1016/j.clpt.2003.11.143

By:

Cho, J.;
Hong, K.;
Chung, J.;
Oh, D.;
Kim, J.;
Lim, H.;
Yi, S.;
Chung, H.;
Liu, K.;
Shin, J.;
Yu, K.;
Shin, S.;
Jang, I.

Publication type:

Article

In vitro-in vivo extrapolation of CYP2D6 inactivation by paroxetine: prediction of nonstationary pharmacokinetics and drug interaction magnitude.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P38, doi. 10.1016/j.clpt.2003.11.144

By:

Venkatakrishnan, K.;
Obach, R.;
Bertelsen, K.;
von Moltke, L. L.;
Greenblatt, D. J.

Publication type:

Article

Delayed disposition of cocaine in sweat patches and in skin blister: cocaine may migrate from plasma to sweat patches via interstitial fluid.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P44, doi. 10.1016/j.clpt.2003.11.163

By:

Uemura, N.;
Harkey, M. R.;
Nath, R. P.;
Henderson, G. L.;
Mendelson, J. E.;
Jones, R. T.

Publication type:

Article

Ephedra and caffeine produce insulin resistance and hypokalemia in healthy subjects.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P44, doi. 10.1016/j.clpt.2003.11.165

By:

Haller, C. A.;
Benowitz, N. L.

Publication type:

Article

Oral contraceptives induce CYP2A6 activity and accelerate nicotine metabolism.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 2, p. P36, doi. 10.1016/j.clpt.2003.11.135

By:

Benowitz, N. L.;
Swan, G. L.;
Lessov, C. N.;
Jacob, P.

Publication type:

Article