Works in Clinical Pharmacology & Therapeutics, 2023, Vol 114, Issue 3

Results: 28

In this Issue.

Published in:: Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 491, doi. 10.1002/cpt.2998
Publication type:: Article

ASCPT News.

Published in:: Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 499, doi. 10.1002/cpt.2997
Publication type:: Article

Clinical Pharmacology and Translational Considerations in the Development of CRISPR‐Based Therapies.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 591, doi. 10.1002/cpt.3000

By:

Abdelhady, Ahmed M.;
Phillips, Jonathan A.;
Xu, Yuanxin;
Stroh, Mark

Publication type:

Article

Novel Therapeutic Modalities: The Future is Now.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 493, doi. 10.1002/cpt.2996

By:

Choi, Yewon;
Vinks, Alexander A.;
van der Graaf, Piet H.

Publication type:

Article

Assessing Information Gaps Associated with Initial Pediatric Study Plans for New Oncology Drug and Biological Products.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 618, doi. 10.1002/cpt.2995

By:

Guinn, Daphne;
Gafford, Marilyn;
Burckart, Gilbert J.;
Reaman, Gregory;
Charlab, Rosane

Publication type:

Article

Highlights.

Published in:: Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 497, doi. 10.1002/cpt.2993
Publication type:: Article

Bioanalytical Methods for Characterization of CAR‐T Cellular Kinetics: Comparison of PCR Assays and Matrices.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 664, doi. 10.1002/cpt.2991

By:

Masilamani, Madhan;
Jawa, Vibha;
Dai, Yanshan;
Das, Romita;
Park, Alice;
Lamba, Manisha;
Wu, Fan;
Zheng, Xirong;
Lu, Edwin;
Gleason, Carol;
Mack, Tim;
Mora, Johanna;
Surapaneni, Sekhar

Publication type:

Article

Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 693, doi. 10.1002/cpt.2973

By:

Bansal, Sumit;
Zamarripa, C. Austin;
Spindle, Tory R.;
Weerts, Elise M.;
Thummel, Kenneth E.;
Vandrey, Ryan;
Paine, Mary F.;
Unadkat, Jashvant D.

Publication type:

Article

Best Practices and Considerations for Clinical Pharmacology and Pharmacometric Aspects for Optimal Development of CAR‐T and TCR‐T Cell Therapies: An Industry Perspective.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 530, doi. 10.1002/cpt.2986

By:

Mody, Hardik;
Ogasawara, Ken;
Zhu, Xu;
Miles, Dale;
Shastri, Prathap Nagaraja;
Gokemeijer, Jochem;
Liao, Michael Z.;
Kasichayanula, Sreeneeranj;
Yang, Tong‐Yuan;
Chemuturi, Nagendra;
Gupta, Swati;
Jawa, Vibha;
Upreti, Vijay V.

Publication type:

Article

Digital Therapeutics as a New Therapeutic Modality: A Review from the Perspective of Clinical Pharmacology.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 578, doi. 10.1002/cpt.2989

By:

Ribba, Benjamin;
Peck, Richard;
Hutchinson, Lucy;
Bousnina, Imein;
Motti, Dario

Publication type:

Article

Clinical Translation of Targeted Protein Degraders.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 558, doi. 10.1002/cpt.2985

By:

Kong, Nikki R.;
Jones, Lyn H.

Publication type:

Article

Prognostic Factors of COVID‐19: An Umbrella Review Endorsed by the International Society for Pharmacoepidemiology.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 604, doi. 10.1002/cpt.2977

By:

Sarri, Grammati;
Liu, Wei;
Zabotka, Luke;
Freitag, Andreas;
Claire, Ravinder;
Wangge, Grace;
Elvidge, Jamie;
Dawoud, Dalia;
Bennett, Dimitri;
Wen, Xuerong;
Li, Xiaojuan;
Rentsch, Christopher T.;
Uddin, Md Jamal;
Ali, M. Sanni;
Gokhale, Mugdha;
Déruaz‐Luyet, Anouk;
Moga, Daniela C.;
Guo, Jeff Jianfei;
Zullo, Andrew R.;
Patorno, Elisabetta

Publication type:

Article

Pharmacologic Heterogeneity and Risk of Severe Hypoglycemia with Concomitant Use of Sulfonylureas and DPP‐4 Inhibitors: Population‐Based Cohort Study.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 712, doi. 10.1002/cpt.2975

By:

Dimakos, Jenny;
Cui, Ying;
Platt, Robert W.;
Renoux, Christel;
Filion, Kristian B.;
Douros, Antonios

Publication type:

Article

Model‐Informed Approaches and Innovative Clinical Trial Design for Adeno‐Associated Viral Vector‐Based Gene Therapy Product Development: A White Paper.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 515, doi. 10.1002/cpt.2972

By:

Mitra, Amitava;
Ahmed, Mariam A.;
Krishna, Rajesh;
Sun, Kefeng;
Gibbons, Francis D.;
Campagne, Olivia;
Rayad, Noha;
Roman, Youssef M.;
Albusaysi, Salwa;
Burian, Maria;
Younis, Islam R.

Publication type:

Article

Considerations for Cell and Gene Therapy Programs Entering the Clinical Space.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 569, doi. 10.1002/cpt.2971

By:

Walford, Geoffrey A.;
Bautmans, An;
Cannon, Carol;
Duncan, Kelly E.;
Deschamps, Kathleen;
Matthews, Randolph P.;
Nussbaum, Jesse;
Stoch, S. Aubrey

Publication type:

Article

T1dCteGui: A User‐Friendly Clinical Trial Enrichment Tool to Optimize T1D Prevention Studies by Leveraging AI/ML Based Synthetic Patient Population.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 704, doi. 10.1002/cpt.2976

By:

Pauley, Mike;
Henscheid, Nick;
David, Sarah E.;
Karpen, Stephen R.;
Romero, Klaus;
Podichetty, Jagdeep T.

Publication type:

Article

Hypoxia Associated With Dihydropyridine Calcium Channel Inhibitors: A Pharmacovigilance Study in VigiBase.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 686, doi. 10.1002/cpt.2970

By:

Chrétien, Basile;
Decros, Jean Baptiste;
Suard, Florimond;
Dolladille, Charles;
Fischer, Marc‐Olivier;
Alexandre, Joachim;
Descamps, Richard

Publication type:

Article

Mechanistic, Functional, and Clinical Aspects of Pro‐inflammatory Cytokine Mediated Regulation of ADME Gene Expression in 3D Human Liver Spheroids.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 673, doi. 10.1002/cpt.2969

By:

Klöditz, Katharina;
Tewolde, Eida;
Nordling, Åsa;
Ingelman‐Sundberg, Magnus

Publication type:

Article

Machine Learning Application Identifies Germline Markers of Hypertension in Patients With Ovarian Cancer Treated With Carboplatin, Taxane, and Bevacizumab.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 652, doi. 10.1002/cpt.2960

By:

Polano, Maurizio;
Bedon, Luca;
Dal Bo, Michele;
Sorio, Roberto;
Bartoletti, Michele;
De Mattia, Elena;
Cecchin, Erika;
Pisano, Carmela;
Lorusso, Domenica;
Lissoni, Andrea Alberto;
De Censi, Andrea;
Cecere, Sabrina Chiara;
Scollo, Paolo;
Marchini, Sergio;
Arenare, Laura;
De Giorgi, Ugo;
Califano, Daniela;
Biagioli, Elena;
Chiodini, Paolo;
Perrone, Francesco

Publication type:

Article

Adopting Model‐Informed Precision‐Dosing for Eculizumab in Transplant Associated‐Thrombotic Microangiopathy to Gene Therapies.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 511, doi. 10.1002/cpt.2966

By:

Jodele, Sonata;
Mizuno, Kana;
Sabulski, Anthony;
Vinks, Alexander A.

Publication type:

Article

Future Opportunities in Drug Development: American Society for Clinical Pharmacology and Therapeutics Pharmacometrics and Pharmacokinetics Community Vision.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 507, doi. 10.1002/cpt.2955

By:

Burton, Jackson;
Abuasal, Bilal;
Bachhav, Sagar;
Connarn, Jamie;
Cosman, Josh;
Gupta, Neeraj;
Jing, Jing;
Kim, Sarah;
Long, Tao;
Terranova, Nadia;
Venkatakrishnan, Karthik;
Wang, Jian;
Liu, Qi

Publication type:

Article

Physician Perspectives on the Food and Drug Administration's Decision to Grant Accelerated Approval to Aducanumab for Alzheimer's Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 614, doi. 10.1002/cpt.2954

By:

Dhruva, Sanket S.;
Kesselheim, Aaron S.;
Woloshin, Steven;
Ji, Robin Z.;
Lu, Zhigang;
Darrow, Jonathan J.;
Redberg, Rita F.

Publication type:

Article

Early Decision Making in a Randomized Phase II Trial of Atezolizumab in Biliary Tract Cancer Using a Tumor Growth Inhibition‐Survival Modeling Framework.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 644, doi. 10.1002/cpt.2953

By:

Shemesh, Colby S.;
Chan, Phyllis;
Marchand, Mathilde;
Gonçalves, Antonio;
Vadhavkar, Shweta;
Wu, Benjamin;
Li, Chunze;
Jin, Jin Y.;
Hack, Stephen P.;
Bruno, Rene

Publication type:

Article

A Quantitative Systems Pharmacology Model Describing the Cellular Kinetic‐Pharmacodynamic Relationship for a Live Biotherapeutic Product to Support Microbiome Drug Development.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 633, doi. 10.1002/cpt.2952

By:

Renardy, Marissa;
Prokopienko, Alexander J.;
Maxwell, Joseph R.;
Flusberg, Deborah A.;
Makaryan, Sahak;
Selimkhanov, Jangir;
Vakilynejad, Majid;
Subramanian, Kalyanasundaram;
Wille, Lucia

Publication type:

Article

Assessment of Clinical Response to V937 Oncolytic Virus After Intravenous or Intratumoral Administration Using Physiologically‐Based Modeling.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 623, doi. 10.1002/cpt.2937

By:

Parra‐Guillen, Zinnia P.;
Sancho‐Araiz, Aymara;
Mayawala, Kapil;
Zalba, Sara;
Garrido, Maria J.;
de Alwis, Dinesh;
Troconiz, Iñaki F.;
Freshwater, Tomoko

Publication type:

Article

Erratum to: ASCPT Abstract PII‐054: Effect of Complement Factor 5A Receptor 1 (C5AR1) Antagonist ACT‐101‐6450 on the Cytochrome P450 2C19 and 3A4 Substrates Omeprazole and Midazolam in a Cocktail Study in Healthy Subjects.

Published in:: Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 721, doi. 10.1002/cpt.2916
Publication type:: Article

Successes and Opportunities during the Pandemic: Reflections and Revelations from a Vaccine Development Perspective.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 504, doi. 10.1002/cpt.2889

By:

Heaton, Penny M.;
Palaniappan, Kavitha;
Stona, Anne‐Claire;
Vogel, Silke;
Lim, John C. W.

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 483, doi. 10.1002/cpt.2661
Publication type:: Article