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ASCPT News.
Published in:
2022
Publication type:
Proceeding
How a Pandemic Simultaneously Strengthened Existing Fundamentals and Drove New Innovations in Clinical Pharmacology.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1141, doi. 10.1002/cpt.2758
By:
- Seo, Shirley K.;
- van der Graaf, Piet H.
Publication type:
Article
Off‐Label, but on‐Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1243, doi. 10.1002/cpt.2736
By:
- van der Zanden, Tjitske M.;
- Smeets, Nori J.L.;
- de Hoop‐Sommen, Marika;
- Schwerzel, Michiel F.T.;
- Huang, Hui Jun;
- Barten, Lieke J.C.;
- van der Heijden, Joyce E.M.;
- Freriksen, Jolien J.M.;
- Horstink, Akira A.L.;
- Holsappel, Inge H.G.;
- Mooij, Miriam G.;
- de Hoog, Matthijs;
- de Wildt, Saskia N.
Publication type:
Article
The Broader Context of Liquid Biopsy in Absorption, Distribution, Metabolism, and Elimination.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1154, doi. 10.1002/cpt.2734
By:
- Rowland, Andrew;
- Useckaite, Zivile;
- Sorich, Michael J.
Publication type:
Article
Response to Rowland et al. and Achour et al.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1155, doi. 10.1002/cpt.2733
By:
- Pridgeon, Chris S.;
- Johansson, Inger;
- Ingelman‐Sundberg, Magnus
Publication type:
Article
Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1145, doi. 10.1002/cpt.2756
Publication type:
Article
Cost Effectiveness of Pharmacogenetic Testing for Drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines: A Systematic Review.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1318, doi. 10.1002/cpt.2754
By:
- Morris, Sarah A.;
- Alsaidi, Ashraf T.;
- Verbyla, Allison;
- Cruz, Adilen;
- Macfarlane, Casey;
- Bauer, Joseph;
- Patel, Jai N.
Publication type:
Article
Is Liquid Biopsy Only Restricted to Diagnostics or Can it Go Beyond the Confines of Genotyping and Phenotyping for Quantitative Pharmacology?
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1152, doi. 10.1002/cpt.2732
By:
- Achour, Brahim;
- Rostami‐Hodjegan, Amin
Publication type:
Article
Integration of Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy into Model‐Informed Dose Selection in Oncology First‐in‐Human Study: A Case of Roblitinib (FGF401).
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1329, doi. 10.1002/cpt.2752
By:
- Wilbaux, Mélanie;
- Yang, Shu;
- Jullion, Astrid;
- Demanse, David;
- Porta, Diana Graus;
- Myers, Andrea;
- Meille, Christophe;
- Gu, Yi
Publication type:
Article
In This Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1139, doi. 10.1002/cpt.2751
Publication type:
Article
Pharmacogenomic Testing and Depressive Symptom Remission: A Systematic Review and Meta‐Analysis of Prospective, Controlled Clinical Trials.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1303, doi. 10.1002/cpt.2748
By:
- Brown, Lisa C.;
- Stanton, Joseph D.;
- Bharthi, Kanika;
- Maruf, Abdullah Al;
- Müller, Daniel J.;
- Bousman, Chad A.
Publication type:
Article
Population PK and PD Analysis of Domagrozumab in Pediatric Patients with Duchenne Muscular Dystrophy.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1291, doi. 10.1002/cpt.2747
By:
- Wojciechowski, Jessica;
- Purohit, Vivek S.;
- Harnisch, Lutz O.;
- Dua, Pinky;
- Tan, Beesan;
- Nicholas, Timothy
Publication type:
Article
Changes in Sertraline Plasma Concentrations Across Pregnancy and Postpartum.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1280, doi. 10.1002/cpt.2746
By:
- Stika, Catherine S.;
- Wisner, Katherine L.;
- George, Alfred L.;
- Avram, Michael J.;
- Zumpf, Katelyn;
- Rasmussen‐Torvik, Laura J.;
- Mesches, Gabrielle A.;
- Caritis, Steve N.;
- Venkataramanan, Raman;
- Costantine, Maged M.;
- West, Holly A.;
- Clark, Shannon;
- Ciolino, Jody D.
Publication type:
Article
Safety and Dosing Study of a Cholecystokinin Receptor Antagonist in Non‐alcoholic Steatohepatitis.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1271, doi. 10.1002/cpt.2745
By:
- Rabiee, Atoosa;
- Gay, Martha D.;
- Shivapurkar, Narayan;
- Cao, Hong;
- Nadella, Sandeep;
- Smith, Coleman I.;
- Lewis, James H.;
- Bansal, Sunil;
- Cheema, Amrita;
- Kwagyan, John;
- Smith, Jill P.
Publication type:
Article
Studying Telmisartan Plasma Exposure, Kidney Distribution, Receptor Occupancy, and Response in Patients With Type 2 Diabetes Using [<sup>11</sup>C]Telmisartan.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1264, doi. 10.1002/cpt.2744
By:
- van der Hoek, Sjoukje;
- Mulder, Douwe J.;
- Willemsen, Antoon T.M.;
- Visser, Ton;
- Heeres, Andre;
- Slart, Riemer H.J.A.;
- Elsinga, Philip H.;
- Heerspink, Hiddo J.L.;
- Stevens, Jasper
Publication type:
Article
Physiologically‐Based Pharmacokinetic Model Development, Validation, and Application for Prediction of Eliglustat Drug–Drug Interactions.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1254, doi. 10.1002/cpt.2738
By:
- Sahasrabudhe, Siddhee A.;
- Cheng, Shen;
- Al‐Kofahi, Mahmoud;
- Jarnes, Jeanine R.;
- Weinreb, Neal J.;
- Kartha, Reena V.
Publication type:
Article
DNA‐Thioguanine Nucleotides as a Marker for Thiopurine Induced Late Leukopenia after Dose Optimizing by NUDT15 C415T in Chinese Patients with IBD.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1236, doi. 10.1002/cpt.2730
By:
- Zhu, Xia;
- Chao, Kang;
- Yang, Ting;
- Wang, Xue‐ding;
- Guan, Shaoxing;
- Tang, Jian;
- Xie, Wen;
- Yu, Ai‐ming;
- Yang, Qing fan;
- Li, Miao;
- Yang, Hong‐sheng;
- Diao, Na;
- Hu, Pin‐jin;
- Gao, Xiang;
- Huang, Min
Publication type:
Article
Sotrovimab Lowers the Risk of COVID‐19 Related Hospitalization or Death in a Large Population Cohort in the United Arab Emirates.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1214, doi. 10.1002/cpt.2700
By:
- Saheb Sharif‐Askari, Fatemeh;
- Ali Hussain Alsayed, Hawra;
- Tleyjeh, Imad;
- Saheb Sharif‐Askari, Narjes;
- Al Sayed Hussain, Ali;
- Saddik, Basema;
- Hamid, Qutayba;
- Halwani, Rabih
Publication type:
Article
Assessing the Combined Public Health Impact of Pharmaceutical Interventions on Pandemic Transmission and Mortality: An Example in SARS CoV‐2.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1224, doi. 10.1002/cpt.2728
By:
- Kamal, Mohamed A.;
- Kuznik, Andreas;
- Qi, Luyuan;
- Więcek, Witold;
- Hussein, Mohamed;
- Hassan, Hazem E.;
- Patel, Kashyap;
- Obadia, Thomas;
- Toroghi, Masood Khaksar;
- Conrado, Daniela J.;
- Al‐Huniti, Nidal;
- Casciano, Roman;
- O'Brien, Meagan P.;
- Barnabas, Ruanne V.;
- Cohen, Myron S.;
- Smith, Patrick F.
Publication type:
Article
Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS‐CoV‐2 Infection.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1207, doi. 10.1002/cpt.2706
By:
- Bender Ignacio, Rachel A.;
- Wohl, David A.;
- Arends, Rosalin;
- Pilla Reddy, Venkatesh;
- Mu, Ying;
- Javan, Arzhang Cyrus;
- Hughes, Michael D.;
- Eron, Joseph J.;
- Currier, Judith S.;
- Smith, Davey;
- Chew, Kara W.;
- Gibbs, Michael;
- Fletcher, Courtney V.
Publication type:
Article
Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1201, doi. 10.1002/cpt.2683
By:
- Singh, Ravi Shankar P.;
- Walker, Gregory S.;
- Kadar, Eugene P.;
- Cox, Loretta M.;
- Eng, Heather;
- Sharma, Raman;
- Bergman, Arthur J.;
- Van Eyck, Lien;
- Hackman, Frances;
- Toussi, Sima S.;
- Kalgutkar, Amit S.;
- Obach, R. Scott
Publication type:
Article
Recommendations for the Management of Drug–Drug Interactions Between the COVID‐19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1191, doi. 10.1002/cpt.2646
By:
- Marzolini, Catia;
- Kuritzkes, Daniel R.;
- Marra, Fiona;
- Boyle, Alison;
- Gibbons, Sara;
- Flexner, Charles;
- Pozniak, Anton;
- Boffito, Marta;
- Waters, Laura;
- Burger, David;
- Back, David J.;
- Khoo, Saye
Publication type:
Article
Managing Potential Drug Interactions of Nirmatrelvir/Ritonavir in COVID‐19 Patients: A Perspective from an Israeli Cross‐Sector Collaboration.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1156, doi. 10.1002/cpt.2610
By:
- Guy‐Alfandary, Shiri;
- Zhurat, Sasha;
- Berlin, Maya;
- De Haan, Tal;
- Gueta, Itai;
- Shihmanter, Renata;
- Golik, Ahuva;
- Berkovitch, Matitiahu;
- Eyal, Sara;
- Goldstein, Lee H.
Publication type:
Article
Estimands and Complex Innovative Designs.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1183, doi. 10.1002/cpt.2575
By:
- Collignon, Olivier;
- Schiel, Anja;
- Burman, Carl‐Fredrik;
- Rufibach, Kaspar;
- Posch, Martin;
- Bretz, Frank
Publication type:
Article
The Current Landscape and Emerging Applications for Real‐World Data in Diagnostics and Clinical Decision Support and its Impact on Regulatory Decision Making.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1172, doi. 10.1002/cpt.2565
By:
- Baumfeld Andre, Elodie;
- Carrington, Nate;
- Siami, Flora S.;
- Hiatt, Jo Carol;
- McWilliams, Carly;
- Hiller, Carolyn;
- Surinach, Andy;
- Zamorano, Alejandro;
- Pashos, Chris L.;
- Schulz, Wade L.
Publication type:
Article
PharmVar GeneFocus: CYP3A5.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1159, doi. 10.1002/cpt.2563
By:
- Rodriguez‐Antona, Cristina;
- Savieo, Jessica L.;
- Lauschke, Volker M.;
- Sangkuhl, Katrin;
- Drögemöller, Britt I.;
- Wang, Danxin;
- van Schaik, Ron H. N.;
- Gilep, Andrei A.;
- Peter, Arul P.;
- Boone, Erin C.;
- Ramey, Bronwyn E.;
- Klein, Teri E.;
- Whirl‐Carrillo, Michelle;
- Pratt, Victoria M.;
- Gaedigk, Andrea
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1131, doi. 10.1002/cpt.2303
Publication type:
Article

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