Works in Clinical Pharmacology & Therapeutics, 2018, Vol 104, Issue 1

Results: 28

In This Issue.

Published in:: 2018
Publication type:: Table of Contents

Highlights.

Published in:: Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 12, doi. 10.1002/cpt.1107
Publication type:: Article

ASCPT News.

Published in:: Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 14, doi. 10.1002/cpt.1106
Publication type:: Article

Digital Technology: The Future Is Bright.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 9, doi. 10.1002/cpt.1092

By:

Smith, Brian;
Sverdlov, Alex

Publication type:

Article

Smartphones Democratize Advanced Biomedical Instruments and Foster Innovation.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 38, doi. 10.1002/cpt.1081

By:

Ceylan Koydemir, Hatice;
Ozcan, Aydogan

Publication type:

Article

Optimizing Digital Integrated Care via Micro‐Randomized Trials.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 53, doi. 10.1002/cpt.1079

By:

Walton, Ashley;
Murphy, Susan;
Nahum‐Shani, Inbal;
Crosby, Lori;
Klasnja, Predrag

Publication type:

Article

Brain Monitoring Devices in Neuroscience Clinical Research: The Potential of Remote Monitoring Using Sensors, Wearables, and Mobile Devices.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 59, doi. 10.1002/cpt.1077

By:

Byrom, Bill;
McCarthy, Marie;
Muehlhausen, Willie;
Schueler, Peter

Publication type:

Article

Reduced Variability to Aspirin Antiplatelet Effect by the Coadministration of Statins in High‐Risk Patients for Cardiovascular Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 111, doi. 10.1002/cpt.1075

By:

Tacconelli, Stefania;
Dovizio, Melania;
Di Francesco, Luigia;
D'Agostino, Ilaria;
Bruno, Annalisa;
Patrignani, Paola;
Capone, Marta L.;
Grossi, Linda;
Ballerini, Patrizia;
Meneguzzi, Alessandra;
Fava, Cristiano;
Minuz, Pietro;
Evangelista, Virgilio;
Manarini, Stefano;
Porreca, Ettore;
Di Febbo, Concetta;
Levantesi, Giacomo

Publication type:

Article

Model‐Informed Drug Development and Review for Generic Products: Summary of FDA Public Workshop.

Published in:

2018

By:

Fang, Lanyan;
Kim, Myong‐Jin;
Li, Zhichuan;
Lionberger, Robert;
Zhao, Liang;
Wang, Yaning;
DiLiberti, Charles E.;
Au, Jessie;
Hooker, Andrew;
Ducharme, Murray P.

Publication type:

Proceeding

CYP‐Mediated Drug–Drug Interaction Is Not a Major Determinant of Attenuation of Antiplatelet Function of Clopidogrel by Vonoprazan.

Published in:

2018

By:

Nishihara, Mitsuhiro;
Czerniak, Richard

Publication type:

Letter to the Editor

Response to “CYP‐Mediated Drug–Drug Interaction Is Not a Major Determinant of Attenuation of Antiplatelet Function of Clopidogrel by Vonoprazan”.

Published in:

2018

By:

Kagami, Takuma;
Furuta, Takahisa

Publication type:

Letter to the Editor

Patient Enrichment for Precision‐Based Cancer Clinical Trials: Using Prospective Cohort Surveillance as an Approach to Improve Clinical Trials.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 23, doi. 10.1002/cpt.1051

By:

Dalton, William S.;
Sullivan, Daniel;
Ecsedy, Jeffrey;
Caligiuri, Michael A.

Publication type:

Article

Digital Therapeutics: An Integral Component of Digital Innovation in Drug Development.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 72, doi. 10.1002/cpt.1036

By:

Sverdlov, Oleksandr;
van Dam, Joris;
Hannesdottir, Kristin;
Thornton‐Wells, Tricia

Publication type:

Article

Heterogeneity of Clinical Trials for Antihypertensive Drugs in Japan: Exploratory Analysis of Confirmatory Phase III Trials Used for Marketing Approval.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 120, doi. 10.1002/cpt.922

By:

Kaneko, Reina;
Sano, Kota;
Ono, Shunsuke

Publication type:

Article

Can the Use of Novel Digital Devices Improve the Productivity of Drug Development?

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 35, doi. 10.1002/cpt.989

By:

Rogozinska, Monika Z.

Publication type:

Article

Leveraging Big Data in Pediatric Development Programs: Proceedings From the 2016 American College of Clinical Pharmacology Annual Meeting Symposium.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 81, doi. 10.1002/cpt.975

By:

Mulugeta, Lily (Yeruk);
Yao, Lynne;
Florian, Jeffrey;
Mould, Diane;
Jacobs, Brian;
Smith, Brian;
Sinha, Vikram;
Barrett, Jeffrey S.

Publication type:

Article

Wearable Devices in Clinical Trials: Hype and Hypothesis.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 42, doi. 10.1002/cpt.966

By:

Izmailova, Elena S.;
Wagner, John A.;
Perakslis, Eric D.

Publication type:

Article

PharmCAT: A Pharmacogenomics Clinical Annotation Tool.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 19, doi. 10.1002/cpt.928

By:

Klein, Teri E.;
Ritchie, Marylyn D.

Publication type:

Article

Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 88, doi. 10.1002/cpt.1013

By:

Shebley, Mohamad;
Emami Riedmaier, Arian;
Beneton, Maud;
Bouzom, Francois;
Chen, Jun;
Djebli, Nassim;
Chen, Yuan;
Yoshida, Kenta;
Cleary, Yumi;
Collins, Christiane;
Dickinson, Gemma L.;
Einolf, Heidi J.;
Huth, Felix;
Khalil, Feras;
Sandhu, Punam;
Lin, Jing;
Odinecs, Aleksandrs;
Patel, Chirag;
Schuck, Edgar;
Wu, Shu‐Pei

Publication type:

Article

TSPYL Family Regulates CYP17A1 and CYP3A4 Expression: Potential Mechanism Contributing to Abiraterone Response in Metastatic Castration‐Resistant Prostate Cancer.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 201, doi. 10.1002/cpt.907

By:

Qin, Sisi;
Liu, Duan;
Niu, Nifang;
Yu, Jia;
Weinshilboum, Richard M.;
Wang, Liewei;
Kohli, Manish;
Wang, Liguo;
Vedell, Peter T.;
Hillman, David W.

Publication type:

Article

Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 188, doi. 10.1002/cpt.905

By:

Bui, Khanh H.;
Li, Jianguo;
Xu, Hongmei;
Al‐Huniti, Nidal;
Zhou, Diansong;
Zhou, Wangda;
Johnson, Trevor N.;
Cheung, S. Y. Amy

Publication type:

Article

European Marketing Authorizations Granted Based on a Single Pivotal Clinical Trial: The Rule or the Exception?

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 169, doi. 10.1002/cpt.900

By:

Morant, Anne Vinther;
Vestergaard, Henrik Tang

Publication type:

Article

Variants in the CYP2B6 3′UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 130, doi. 10.1002/cpt.892

By:

Burgess, Kimberly S.;
Ipe, Joseph;
Swart, Marelize;
Metzger, Ingrid F.;
Lu, Jessica;
Gufford, Brandon T.;
Thong, Nancy;
Desta, Zeruesenay;
Skaar, Todd C.;
Gaedigk, Roger;
Pearce, Robin E.;
Gaedigk, Andrea;
Liu, Yunlong

Publication type:

Article

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 158, doi. 10.1002/cpt.891

By:

Hirvensalo, Päivi;
Tornio, Aleksi;
Neuvonen, Mikko;
Tapaninen, Tuija;
Paile‐Hyvärinen, Maria;
Backman, Janne T.;
Niemi, Mikko;
Kärjä, Vesa;
Männistö, Ville T.;
Pihlajamäki, Jussi

Publication type:

Article

Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug–Drug Interactions.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 148, doi. 10.1002/cpt.889

By:

Matthey, Alain;
Storelli, Flavia;
Desmeules, Jules;
Daali, Youssef;
Lenglet, Sébastien;
Thomas, Aurélien

Publication type:

Article

Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 139, doi. 10.1002/cpt.888

By:

Bauer, Martin;
Matsuda, Akihiro;
Wulkersdorfer, Beatrix;
Zeitlinger, Markus;
Langer, Oliver;
Stanek, Johann;
Philippe, Cécile;
Nics, Lukas;
Klebermass, Eva‐Maria;
Hacker, Marcus;
Wadsak, Wolfgang;
Traxl, Alexander;
Özvegy‐Laczka, Csilla;
Patik, Izabel;
Bakos, Éva;
Szakács, Gergely;
Poschner, Stefan;
Jäger, Walter

Publication type:

Article

Genetic and Clinical Factors Are Associated With Statin‐Related Myotoxicity of Moderate Severity: A Case–Control Study.

Published in:

Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 178, doi. 10.1002/cpt.887

By:

Bakar, Nur Salwani;
Daly, Ann K.;
Kamali, Farhad;
Neely, Dermot;
Avery, Peter;
Brown, Colin

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 1, doi. 10.1002/cpt.839
Publication type:: Article