Works matching IS 00071188 AND DT 2024 AND VI 181 AND IP 21

Results: 19

Advances in binding kinetics and mechanistic PK/PD modelling.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4089, doi. 10.1111/bph.17340
By:
- Srinivasan, Bharath
Publication type:
Article
Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4152, doi. 10.1111/bph.17308
By:
- Tong, Yuquan;
- Childs‐Disney, Jessica L.;
- Disney, Matthew D.
Publication type:
Article
Ticagrelor increases its own potency at the P2Y12 receptor by directly changing the plasma membrane lipid order in platelets.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4369, doi. 10.1111/bph.16500
By:
- Pyrshev, Kyrylo;
- Allemand, Florentin;
- Rabani, Vahideh;
- Yesylevskyy, Semen;
- Davani, Siamak;
- Ramseyer, Christophe;
- Lagoutte‐Renosi, Jennifer
Publication type:
Article
Arbidol, an antiviral drug, identified as a sodium channel blocker with anticonvulsant activity.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4311, doi. 10.1111/bph.16496
By:
- Li, Min;
- Jin, Yuchen;
- Wu, Jun;
- Zhao, Miao;
- Yu, Kexin;
- Yu, Haibo
Publication type:
Article
Repurposing cyclovirobuxine D as a novel inhibitor of colorectal cancer progression via modulating the CCT3/YAP axis.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4348, doi. 10.1111/bph.16494
By:
- Liu, Yiman;
- Chen, Lu;
- Wang, Jinghui;
- Bao, Xiaomei;
- Huang, Jiayan;
- Qiu, Yuling;
- Wang, Tao;
- Yu, Haiyang
Publication type:
Article
Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4294, doi. 10.1111/bph.16493
By:
- Doiron, Jake E.;
- Xia, Huijing;
- Yu, Xiaoman;
- Nevins, Alexandra R.;
- LaPenna, Kyle B.;
- Sharp, Thomas E.;
- Goodchild, Traci T.;
- Allerton, Timothy D.;
- Elgazzaz, Mona;
- Lazartigues, Eric;
- Shah, Sanjiv J.;
- Li, Zhen;
- Lefer, David J.
Publication type:
Article
A vitamin D‐based strategy overcomes chemoresistance in prostate cancer.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4279, doi. 10.1111/bph.16492
By:
- Len‐Tayon, Kateryna;
- Beraud, Claire;
- Fauveau, Clara;
- Belorusova, Anna Y.;
- Chebaro, Yassmine;
- Mouriño, Antonio;
- Massfelder, Thierry;
- Chauchereau, Anne;
- Metzger, Daniel;
- Rochel, Natacha;
- Laverny, Gilles
Publication type:
Article
A highly selective inhibitor of discoidin domain receptor‐1 (DDR1‐IN‐1) protects corneal epithelial cells from YAP/ACSL4‐mediated ferroptosis in dry eye.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4245, doi. 10.1111/bph.16491
By:
- Dai, Yiqin;
- Li, Yue;
- Xu, Jianjiang;
- Zhang, Jing
Publication type:
Article
Direct measurements of neurosteroid binding to specific sites on GABAA receptors.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4229, doi. 10.1111/bph.16490
By:
- Chintala, Satyanarayana M.;
- Tateiwa, Hiroki;
- Qian, Mingxing;
- Xu, Yuanjian;
- Amtashar, Fatima;
- Chen, Zi‐Wei;
- Kirkpatrick, Charles C.;
- Bracamontes, John;
- Germann, Allison L.;
- Akk, Gustav;
- Covey, Douglas F.;
- Evers, Alex S.
Publication type:
Article
Coptisine exerts anti‐tumour effects in triple‐negative breast cancer by targeting mitochondrial complex I.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4262, doi. 10.1111/bph.16489
By:
- Shen, Yunfu;
- Yang, You;
- Wang, Zi;
- Lin, Wanjun;
- Feng, Na;
- Shi, Meina;
- Liu, Jiachen;
- Ma, Wenzhe
Publication type:
Article
Inhibition of dynamin‐related protein 1‐filamin interaction improves systemic glucose metabolism.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4328, doi. 10.1111/bph.16487
By:
- Kato, Yuri;
- Ariyoshi, Kohei;
- Nohara, Yasunobu;
- Matsunaga, Naoya;
- Shimauchi, Tsukasa;
- Shindo, Naoya;
- Nishimura, Akiyuki;
- Mi, Xinya;
- Kim, Sang Geon;
- Ide, Tomomi;
- Kawanishi, Eiji;
- Ojida, Akio;
- Nakashima, Naoki;
- Mori, Yasuo;
- Nishida, Motohiro
Publication type:
Article
Combination therapy enhances efficacy and overcomes toxicity of metal‐based anti‐diabetic agent.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4214, doi. 10.1111/bph.16485
By:
- Shang, Bing;
- Dong, Yaqiong;
- Feng, Bo;
- Zhao, Jingyan;
- Wang, Zhi;
- Crans, Debbie C.;
- Yang, Xiaoda
Publication type:
Article
Spexin inhibits excessive autophagy‐induced ferroptosis to alleviate doxorubicin‐induced cardiotoxicity by upregulating Beclin 1.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4195, doi. 10.1111/bph.16484
By:
- Ou, Wen;
- Liu, Haiqiong;
- Chen, Changhai;
- Yang, Chaobo;
- Zhao, Xiaoqing;
- Zhang, Yu;
- Zhang, Zhiyin;
- Huang, Shuwen;
- Mo, Huaqiang;
- Lu, Weizhe;
- Wang, Xianbao;
- Chen, Aihua;
- Yan, Jing;
- Song, Xudong
Publication type:
Article
Inhibition of proline‐rich tyrosine kinase 2 restores cardioprotection by remote ischaemic preconditioning in type 2 diabetes.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4174, doi. 10.1111/bph.16483
By:
- Erkens, Ralf;
- Duse, Dragos Andrei;
- Brum, Amanda;
- Chadt, Alexandra;
- Becher, Stefanie;
- Siragusa, Mauro;
- Quast, Christine;
- Müssig, Johanna;
- Roden, Michael;
- Cortese‐Krott, Miriam;
- Ibáñez, Borja;
- Lammert, Eckhard;
- Fleming, Ingrid;
- Jung, Christian;
- Al‐Hasani, Hadi;
- Heusch, Gerd;
- Kelm, Malte
Publication type:
Article
The translational value of ligand‐receptor binding kinetics in drug discovery.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4117, doi. 10.1111/bph.16241
By:
- Liu, Hongli;
- Zhang, Haoran;
- IJzerman, Adriaan P.;
- Guo, Dong
Publication type:
Article
Kinetic analysis of fluorescent ligand binding to cell surface receptors: Insights into conformational changes and allosterism in living cells.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4091, doi. 10.1111/bph.16185
By:
- Hill, Stephen J.;
- Kilpatrick, Laura E.
Publication type:
Article
Issue Information.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4087, doi. 10.1111/bph.16136
Publication type:
Article
The importance of binding kinetics and drug–target residence time in pharmacology.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4103, doi. 10.1111/bph.16104
By:
- Knockenhauer, Kevin E.;
- Copeland, Robert A.
Publication type:
Article
Soluble GC stimulators and activators: Past, present and future.
Published in:
British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4130, doi. 10.1111/bph.15698
By:
- Sandner, Peter;
- Follmann, Markus;
- Becker‐Pelster, Eva;
- Hahn, Michael G.;
- Meier, Christian;
- Freitas, Cecilia;
- Roessig, Lothar;
- Stasch, Johannes‐Peter
Publication type:
Article

Works matching IS 00071188 AND DT 2024 AND VI 181 AND IP 21

Advances in binding kinetics and mechanistic PK/PD modelling.

Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40.

Ticagrelor increases its own potency at the P2Y<sub>12</sub> receptor by directly changing the plasma membrane lipid order in platelets.

Arbidol, an antiviral drug, identified as a sodium channel blocker with anticonvulsant activity.

Repurposing cyclovirobuxine D as a novel inhibitor of colorectal cancer progression via modulating the CCT3/YAP axis.

Adjunctive therapy with an oral H<sub>2</sub>S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.

A vitamin D‐based strategy overcomes chemoresistance in prostate cancer.

A highly selective inhibitor of discoidin domain receptor‐1 (DDR1‐IN‐1) protects corneal epithelial cells from YAP/ACSL4‐mediated ferroptosis in dry eye.

Direct measurements of neurosteroid binding to specific sites on GABA<sub>A</sub> receptors.

Coptisine exerts anti‐tumour effects in triple‐negative breast cancer by targeting mitochondrial complex I.

Inhibition of dynamin‐related protein 1‐filamin interaction improves systemic glucose metabolism.

Combination therapy enhances efficacy and overcomes toxicity of metal‐based anti‐diabetic agent.

Spexin inhibits excessive autophagy‐induced ferroptosis to alleviate doxorubicin‐induced cardiotoxicity by upregulating Beclin 1.

Inhibition of proline‐rich tyrosine kinase 2 restores cardioprotection by remote ischaemic preconditioning in type 2 diabetes.

The translational value of ligand‐receptor binding kinetics in drug discovery.

Kinetic analysis of fluorescent ligand binding to cell surface receptors: Insights into conformational changes and allosterism in living cells.

Issue Information.

The importance of binding kinetics and drug–target residence time in pharmacology.

Soluble GC stimulators and activators: Past, present and future.