Works matching IS 00071188 AND DT 2022 AND VI 179 AND IP 14

Results: 27

Responsivity of serotonin transporter knockout rats to short and long access to cocaine: Modulation of the glutamate signalling in the nucleus accumbens shell.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3727, doi. 10.1111/bph.15823

By:

Caffino, Lucia;
Mottarlini, Francesca;
Targa, Giorgia;
Verheij, Michel M. M.;
Fumagalli, Fabio;
Homberg, Judith R.

Publication type:

Article

Structure‐based survey of ligand binding in the human insulin receptor.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3512, doi. 10.1111/bph.15777

By:

Kumar, Lokender;
Vizgaudis, Whitney;
Klein‐Seetharaman, Judith

Publication type:

Article

Molecular basis for ligand modulation of the cannabinoid CB1 receptor.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3487, doi. 10.1111/bph.15627

By:

Ramesh, Karthik;
Rosenbaum, Daniel M.

Publication type:

Article

Issue Information.

Published in:: British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3483, doi. 10.1111/bph.15557
Publication type:: Article

Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3592, doi. 10.1111/bph.15327

By:

Eagles, David A.;
Chow, Chun Yuen;
King, Glenn F.

Publication type:

Article

Analysis of covariance: A useful tool for the pharmacologist to reduce variation and improve precision using fewer animals.

Published in:: British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3645, doi. 10.1111/bph.15855
Publication type:: Article

Honokiol ameliorates cisplatin‐induced acute kidney injury via inhibition of mitochondrial fission.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3886, doi. 10.1111/bph.15837

By:

Mao, Rui‐wen;
He, Shan‐ping;
Lan, Jun‐gang;
Zhu, Wu‐zheng

Publication type:

Article

The respiratory depressant effects of mitragynine are limited by its conversion to 7‐OH mitragynine.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3875, doi. 10.1111/bph.15832

By:

Hill, Rob;
Kruegel, Andrew C.;
Javitch, Jonathan A.;
Lane, J. Robert;
Canals, Meritxell

Publication type:

Article

Targeting the cell's gatekeepers for novel drug discovery.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3485, doi. 10.1111/bph.15831

By:

Stephens, Gary J.;
Shukla, Arun K.

Publication type:

Article

P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3859, doi. 10.1111/bph.15830

By:

Gasparri, Federica;
Sarkar, Debayan;
Bielickaite, Sarune;
Poulsen, Mette Homann;
Hauser, Alexander Sebastian;
Pless, Stephan Alexander

Publication type:

Article

Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO‐dependent mechanism.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3839, doi. 10.1111/bph.15827

By:

Tingting, Wang;
Tianqi, Fang;
Xinyu, Wang;
Can, Zhang;
Xue, Shen;
Xuming, Deng;
Jianfeng, Wang

Publication type:

Article

Inhibition of chemically and mechanically activated Piezo1 channels as a mechanism for ameliorating atherosclerosis with salvianolic acid B.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3778, doi. 10.1111/bph.15826

By:

Pan, Xianmei;
Wan, Rentao;
Wang, Yuman;
Liu, Silin;
He, Yu;
Deng, Bo;
Luo, Shangfei;
Chen, Yuan;
Wen, Lizhen;
Hong, Tianying;
Xu, Han;
Bian, Yifei;
Xia, Mingfeng;
Li, Jing

Publication type:

Article

Influx of kynurenine into the brain is involved in the reduction of ethanol consumption induced by Ro 61‐8048 after chronic intermittent ethanol in mice.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3711, doi. 10.1111/bph.15825

By:

Gil de Biedma‐Elduayen, Leticia;
Giménez‐Gómez, Pablo;
Morales‐Puerto, Nuria;
Vidal, Rebeca;
Núñez‐de la Calle, Carlos;
Gutiérrez‐López, María Dolores;
O'Shea, Esther;
Colado, María Isabel

Publication type:

Article

Mechanistic modelling of enzyme‐restoration effects of new recombinant liver‐targeted proteins in acute intermittent porphyria.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3815, doi. 10.1111/bph.15821

By:

Vera‐Yunca, Diego;
Córdoba, Karol M.;
Parra‐Guillen, Zinnia P.;
Jericó, Daniel;
Fontanellas, Antonio;
Trocóniz, Iñaki F.

Publication type:

Article

How far are we from predicting multi‐drug interactions during treatment for COVID‐19 infection?

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3831, doi. 10.1111/bph.15819

By:

Lozano, Benjamin;
Santibáñez, Javier;
Severino, Nicolás;
Saldias, Cristina;
Vera, Magdalena;
Retamal, Jaime;
Torres, Soledad;
Barrera, Nelson P.

Publication type:

Article

Pre‐synaptic and post‐synaptic A‐type K+ channels regulate glutamatergic transmission and switching of the network into epileptiform oscillations.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3754, doi. 10.1111/bph.15818

By:

Wang, Guan‐Hsun;
Chuang, Ai‐Yu;
Lai, Yi‐Chen;
Chen, Hsin‐I;
Hsueh, Shu‐Wei;
Yang, Ya‐Chin

Publication type:

Article

Molecular dynamic and pharmacological studies on protein‐engineered hirudin variants of Hirudinaria manillensis and Hirudo medicinalis.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3740, doi. 10.1111/bph.15816

By:

Sun, Yan;
Wang, Baochun;
Pei, Jinli;
Luo, Ying;
Yuan, Nan;
Xiao, Zhengpan;
Wu, Hao;
Luo, Chenghui;
Wang, Jiaxuan;
Wei, Shuangshuang;
Pei, Yechun;
Fu, Shengmiao;
Wang, Dayong

Publication type:

Article

Community guidelines for GPCR ligand bias: IUPHAR review 32.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3651, doi. 10.1111/bph.15811

By:

Kolb, Peter;
Kenakin, Terry;
Alexander, Stephen P. H.;
Bermudez, Marcel;
Bohn, Laura M.;
Breinholt, Christian S.;
Bouvier, Michel;
Hill, Stephen J.;
Kostenis, Evi;
Martemyanov, Kirill A.;
Neubig, Rick R.;
Onaran, H. Ongun;
Rajagopal, Sudarshan;
Roth, Bryan L.;
Selent, Jana;
Shukla, Arun K.;
Sommer, Martha E.;
Gloriam, David E.

Publication type:

Article

Tricyclic antipsychotics and antidepressants can inhibit α5‐containing GABAA receptors by two distinct mechanisms.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3675, doi. 10.1111/bph.15807

By:

Bampali, Konstantina;
Koniuszewski, Filip;
Silva, Luca L.;
Rehman, Sabah;
Vogel, Florian D.;
Seidel, Thomas;
Scholze, Petra;
Zirpel, Florian;
Garon, Arthur;
Langer, Thierry;
Willeit, Matthäus;
Ernst, Margot

Publication type:

Article

Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3693, doi. 10.1111/bph.15809

By:

Villalba‐Riquelme, Eva;
de la Torre‐Martínez, Roberto;
Fernández‐Carvajal, Asia;
Ferrer‐Montiel, Antonio

Publication type:

Article

Emerging insights into the structure and function of ionotropic glutamate delta receptors.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3612, doi. 10.1111/bph.15313

By:

Burada, Ananth Prasad;
Vinnakota, Rajesh;
Bharti, Pratibha;
Dutta, Priyanka;
Dubey, Neelima;
Kumar, Janesh

Publication type:

Article

Temperature‐sensitive transient receptor potential vanilloid channels: structural insights into ligand‐dependent activation.

Published in:: British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3542, doi. 10.1111/bph.15310
Publication type:: Article

Therapeutic validation of an orphan G protein‐coupled receptor: The case of GPR84.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3529, doi. 10.1111/bph.15248

By:

Marsango, Sara;
Barki, Natasja;
Jenkins, Laura;
Tobin, Andrew B.;
Milligan, Graeme

Publication type:

Article

Pharmacological properties of TRPM3 isoforms are determined by the length of the pore loop.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3560, doi. 10.1111/bph.15223

By:

Held, Katharina;
Aloi, Vincenzo Davide;
Freitas, Ana Cristina Nogueira;
Janssens, Annelies;
Segal, Andrei;
Przibilla, Julia;
Philipp, Stephan Ernst;
Wang, Yu Tian;
Voets, Thomas;
Vriens, Joris

Publication type:

Article

Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3576, doi. 10.1111/bph.15267

By:

Doñate‐Macian, Pablo;
Duarte, Yorley;
Rubio‐Moscardo, Fanny;
Pérez‐Vilaró, Gemma;
Canan, Jonathan;
Díez, Juana;
González‐Nilo, Fernando;
Valverde, Miguel A.

Publication type:

Article

Structural basis of AMPA receptor inhibition by trans‐4‐butylcyclohexane carboxylic acid.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3628, doi. 10.1111/bph.15254

By:

Yelshanskaya, Maria V.;
Singh, Appu K.;
Narangoda, Chamali;
Williams, Robin S.B.;
Kurnikova, Maria G.;
Sobolevsky, Alexander I.

Publication type:

Article

Adenosine A2A receptor antagonists: from caffeine to selective non‐xanthines.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 14, p. 3496, doi. 10.1111/bph.15103

By:

Jacobson, Kenneth A.;
Gao, Zhan‐Guo;
Matricon, Pierre;
Eddy, Matthew T.;
Carlsson, Jens

Publication type:

Article

Works matching IS 00071188 AND DT 2022 AND VI 179 AND IP 14

Responsivity of serotonin transporter knockout rats to short and long access to cocaine: Modulation of the glutamate signalling in the nucleus accumbens shell.

Structure‐based survey of ligand binding in the human insulin receptor.

Molecular basis for ligand modulation of the cannabinoid CB<sub>1</sub> receptor.

Issue Information.

Fifteen years of Na<sub>V</sub>1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?

Analysis of covariance: A useful tool for the pharmacologist to reduce variation and improve precision using fewer animals.

Honokiol ameliorates cisplatin‐induced acute kidney injury via inhibition of mitochondrial fission.

The respiratory depressant effects of mitragynine are limited by its conversion to 7‐OH mitragynine.

Targeting the cell's gatekeepers for novel drug discovery.

P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity.

Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO‐dependent mechanism.

Inhibition of chemically and mechanically activated Piezo1 channels as a mechanism for ameliorating atherosclerosis with salvianolic acid B.

Influx of kynurenine into the brain is involved in the reduction of ethanol consumption induced by Ro 61‐8048 after chronic intermittent ethanol in mice.

Mechanistic modelling of enzyme‐restoration effects of new recombinant liver‐targeted proteins in acute intermittent porphyria.

How far are we from predicting multi‐drug interactions during treatment for COVID‐19 infection?

Pre‐synaptic and post‐synaptic A‐type K<sup>+</sup> channels regulate glutamatergic transmission and switching of the network into epileptiform oscillations.

Molecular dynamic and pharmacological studies on protein‐engineered hirudin variants of Hirudinaria manillensis and Hirudo medicinalis.

Community guidelines for GPCR ligand bias: IUPHAR review 32.

Tricyclic antipsychotics and antidepressants can inhibit α5‐containing GABA<sub>A</sub> receptors by two distinct mechanisms.

Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats.

Emerging insights into the structure and function of ionotropic glutamate delta receptors.

Temperature‐sensitive transient receptor potential vanilloid channels: structural insights into ligand‐dependent activation.

Therapeutic validation of an orphan G protein‐coupled receptor: The case of GPR84.

Pharmacological properties of TRPM3 isoforms are determined by the length of the pore loop.

Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity.

Structural basis of AMPA receptor inhibition by trans‐4‐butylcyclohexane carboxylic acid.

Adenosine A<sub>2A</sub> receptor antagonists: from caffeine to selective non‐xanthines.