Works matching IS 00071188 AND DT 2022 AND VI 179 AND IP 11

Results: 31

Correction.

Published in:: 2022
Publication type:: Journal Article

Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2538, doi. 10.1111/bph.15822

By:

Dello Russo, Cinzia;
Bandiera, Tiziano;
Monici, Monica;
Surdo, Leonardo;
Yip, Vincent Lai Ming;
Wotring, Virginia;
Morbidelli, Lucia

Publication type:

Article

Altered blood–brain barrier and blood–spinal cord barrier dynamics in amyotrophic lateral sclerosis: Impact on medication efficacy and safety.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2577, doi. 10.1111/bph.15802

By:

Pan, Yijun;
Nicolazzo, Joseph A.

Publication type:

Article

Intra‐articular injection of triamcinolone acetonide sustains macrophage levels and aggravates osteophytosis during degenerative joint disease in mice.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2771, doi. 10.1111/bph.15780

By:

Ferrao Blanco, Mauricio N.;
Bastiaansen Jenniskens, Yvonne M.;
Kops, Nicole;
Chavli, Athina;
Narcisi, Roberto;
Botter, Sander M.;
Leenen, Pieter J. M.;
van Osch, Gerjo J. V. M.;
Fahy, Niamh

Publication type:

Article

Recent developments in cGMP research: From mechanisms to medicines and back.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2321, doi. 10.1111/bph.15824

By:

Lukowski, Robert;
Feil, Robert

Publication type:

Article

cGMP signalling in dorsal root ganglia and the spinal cord: Various functions in development and adulthood.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2361, doi. 10.1111/bph.15514

By:

Schmidt, Hannes;
Böttcher, Alexandra;
Gross, Tilman;
Schmidtko, Achim

Publication type:

Article

Linking drug and food addiction via compulsive appetite.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2589, doi. 10.1111/bph.15797

By:

Laque, Amanda;
Wagner, Grant E.;
Matzeu, Alessandra;
De Ness, Genna L.;
Kerr, Tony M.;
Carroll, Ayla M.;
de Guglielmo, Giordano;
Nedelescu, Hermina;
Buczynski, Matthew W.;
Gregus, Ann M.;
Jhou, Thomas C.;
Zorrilla, Eric P.;
Martin‐Fardon, Remi;
Koya, Eisuke;
Ritter, Robert C.;
Weiss, Friedbert;
Suto, Nobuyoshi

Publication type:

Article

Assessing the fidelity of translation of non‐clinical assays: a Pharma perspective.

Published in:: British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2564, doi. 10.1111/bph.15796
Publication type:: Article

Microsomal prostaglandin E synthase‐1 is involved in the metabolic and cardiovascular alterations associated with obesity.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2733, doi. 10.1111/bph.15776

By:

Ballesteros‐Martínez, Constanza;
Rodrigues‐Díez, Raquel;
Beltrán, Luis M.;
Moreno‐Carriles, Rosa;
Martínez‐Martínez, Ernesto;
González‐Amor, María;
Martínez‐González, Jose;
Rodríguez, Cristina;
Cachofeiro, Victoria;
Salaices, Mercedes;
Briones, Ana M.

Publication type:

Article

Bruton's TK regulates myeloid cell recruitment during acute inflammation.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2754, doi. 10.1111/bph.15778

By:

Purvis, Gareth S. D.;
Aranda‐Tavio, Haidee;
Channon, Keith M.;
Greaves, David R.

Publication type:

Article

A carvedilol analogue, VK‐II‐86, prevents hypokalaemia‐induced ventricular arrhythmia through novel multi‐channel effects.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2713, doi. 10.1111/bph.15775

By:

Robinson, Victoria M.;
Alsalahat, Izzeddin;
Freeman, Sally;
Antzelevitch, Charles;
Barajas‐Martinez, Héctor;
Venetucci, Luigi

Publication type:

Article

NO‐sensitive guanylyl cyclase in the lung.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2328, doi. 10.1111/bph.15345

By:

Friebe, Andreas;
Englert, Nils

Publication type:

Article

Stimulation of soluble guanylyl cyclase (sGC) by riociguat attenuates heart failure and pathological cardiac remodelling.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2430, doi. 10.1111/bph.15333

By:

Rüdebusch, Julia;
Benkner, Alexander;
Nath, Neetika;
Fleuch, Lina;
Kaderali, Lars;
Grube, Karina;
Klingel, Karin;
Eckstein, Gertrud;
Meitinger, Thomas;
Fielitz, Jens;
Felix, Stephan B.

Publication type:

Article

Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2697, doi. 10.1111/bph.15774

By:

Maamra, Mabrouka;
Benayad, Osama Mehdi;
Matthews, David;
Kettleborough, Catherine;
Atkinson, John;
Cain, Katharine;
Bon, Helene;
Brand, Helen;
Parkinson, Michael;
Watson, Philip F.;
Johnson, Timothy S.

Publication type:

Article

Ruthenium 360 and mitoxantrone inhibit mitochondrial calcium uniporter channel to prevent liver steatosis induced by high‐fat diet.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2678, doi. 10.1111/bph.15767

By:

Zhang, Zhiwang;
Luo, Zupeng;
Yu, Lin;
Xiao, Yang;
Liu, Siqi;
ALuo, Zhier;
Ma, Zeqiang;
Huang, Liang;
Xiao, Lianggui;
Jia, Mengting;
Song, Ziyi;
Zhang, Haojie;
Li, Yixing;
Zhou, Lei

Publication type:

Article

The antibiotic drug trimethoprim suppresses tumour growth and metastasis via targeting Snail.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2659, doi. 10.1111/bph.15763

By:

Ren, Bo‐Xue;
Li, Yang;
Li, Hong‐Mei;
Lu, Tao;
Wu, Zhao‐Qiu;
Fu, Rong

Publication type:

Article

Genetic deletion or pharmacological blockade of nociceptin/orphanin FQ receptors in the ventral tegmental area attenuates nicotine‐motivated behaviour.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2647, doi. 10.1111/bph.15762

By:

Domi, Ana;
Lunerti, Veronica;
Petrella, Michele;
Domi, Esi;
Borruto, Anna Maria;
Ubaldi, Massimo;
Weiss, Friedbert;
Ciccocioppo, Roberto

Publication type:

Article

Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2631, doi. 10.1111/bph.15757

By:

TeBay, Clifford;
McArthur, Jeffrey R.;
Mangala, Melissa;
Kerr, Nicholas;
Heitmann, Stewart;
Perry, Matthew D.;
Windley, Monique J.;
Vandenberg, Jamie I.;
Hill, Adam P.

Publication type:

Article

A new class of 5‐HT2A/5‐HT2C receptor inverse agonists: Synthesis, molecular modeling, in vitro and in vivo pharmacology of novel 2‐aminotetralins.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2610, doi. 10.1111/bph.15756

By:

Casey, Austen B.;
Mukherjee, Munmun;
McGlynn, Ryan P.;
Cui, Meng;
Kohut, Stephen J.;
Booth, Raymond G.

Publication type:

Article

Moving in the right direction: elucidating the mechanisms of interaction between flecainide and the cardiac ryanodine receptor.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2558, doi. 10.1111/bph.15718

By:

Bannister, Mark L.;
MacLeod, Kenneth T.;
George, Christopher H.

Publication type:

Article

Multidrug resistance proteins preferentially regulate natriuretic peptide‐driven cGMP signalling in the heart and vasculature.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2443, doi. 10.1111/bph.15593

By:

Grange, Robert M. H.;
Preedy, Michael E. J.;
Renukanthan, Aniruthan;
Dignam, Joshua P.;
Lowe, Vanessa J.;
Moyes, Amie J.;
Pérez‐Ternero, Cristina;
Aubdool, Aisah A.;
Baliga, Reshma S.;
Hobbs, Adrian J.

Publication type:

Article

Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2476, doi. 10.1111/bph.15586

By:

Stehle, Daniel;
Xu, Min Ze;
Schomber, Tibor;
Hahn, Michael G.;
Schweda, Frank;
Feil, Susanne;
Kraehling, Jan R.;
Eitner, Frank;
Patzak, Andreas;
Sandner, Peter;
Feil, Robert;
Bénardeau, Agnès

Publication type:

Article

Issue Information.

Published in:: British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2319, doi. 10.1111/bph.15554
Publication type:: Article

cGMP and mitochondrial K+ channels—Compartmentalized but closely connected in cardioprotection.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2344, doi. 10.1111/bph.15536

By:

Lukowski, Robert;
Cruz Santos, Melanie;
Kuret, Anna;
Ruth, Peter

Publication type:

Article

Constitutive protein kinase G activation exacerbates stress‐induced cardiomyopathy.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2413, doi. 10.1111/bph.15530

By:

Schwaerzer, Gerburg K.;
Casteel, Darren E.;
Cividini, Federico;
Kalyanaraman, Hema;
Zhuang, Shunhui;
Gu, Yusu;
Dalton, Nancy D.;
Peterson, Kirk L.;
Dillmann, Wolfgang H.;
Boss, Gerry R.;
Pilz, Renate B.

Publication type:

Article

Inactivation of soluble guanylyl cyclase in living cells proceeds without loss of haem and involves heterodimer dissociation as a common step.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2505, doi. 10.1111/bph.15527

By:

Dai, Yue;
Stuehr, Dennis J.

Publication type:

Article

Angiotensin II augments renal vascular smooth muscle soluble GC expression via an AT1 receptor–forkhead box subclass O transcription factor signalling axis.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2490, doi. 10.1111/bph.15522

By:

Galley, Joseph C.;
Hahn, Scott A.;
Miller, Megan P.;
Durgin, Brittany G.;
Jackson, Edwin K.;
Stocker, Sean D.;
Straub, Adam C.

Publication type:

Article

Visualising and understanding cGMP signals in the cardiovascular system.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2394, doi. 10.1111/bph.15500

By:

Feil, Robert;
Lehners, Moritz;
Stehle, Daniel;
Feil, Susanne

Publication type:

Article

The role of cGMP signalling in auditory processing in health and disease.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2378, doi. 10.1111/bph.15455

By:

Marchetta, Philine;
Rüttiger, Lukas;
Hobbs, Adrian J.;
Singer, Wibke;
Knipper, Marlies

Publication type:

Article

Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide‐gated channels.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2519, doi. 10.1111/bph.15445

By:

Henß, Thilo;
Nagpal, Jatin;
Gao, Shiqiang;
Scheib, Ulrike;
Pieragnolo, Alessia;
Hirschhäuser, Alexander;
Schneider‐Warme, Franziska;
Hegemann, Peter;
Nagel, Georg;
Gottschalk, Alexander

Publication type:

Article

Activation of soluble guanylyl cyclase signalling with cinaciguat improves impaired kidney function in diabetic mice.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2460, doi. 10.1111/bph.15425

By:

Harloff, Manuela;
Prüschenk, Sally;
Seifert, Roland;
Schlossmann, Jens

Publication type:

Article

Works matching IS 00071188 AND DT 2022 AND VI 179 AND IP 11

Correction.

Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature.

Altered blood–brain barrier and blood–spinal cord barrier dynamics in amyotrophic lateral sclerosis: Impact on medication efficacy and safety.

Intra‐articular injection of triamcinolone acetonide sustains macrophage levels and aggravates osteophytosis during degenerative joint disease in mice.

Recent developments in cGMP research: From mechanisms to medicines and back.

cGMP signalling in dorsal root ganglia and the spinal cord: Various functions in development and adulthood.

Linking drug and food addiction via compulsive appetite.

Assessing the fidelity of translation of non‐clinical assays: a Pharma perspective.

Microsomal prostaglandin E synthase‐1 is involved in the metabolic and cardiovascular alterations associated with obesity.

Bruton's TK regulates myeloid cell recruitment during acute inflammation.

A carvedilol analogue, VK‐II‐86, prevents hypokalaemia‐induced ventricular arrhythmia through novel multi‐channel effects.

NO‐sensitive guanylyl cyclase in the lung.

Stimulation of soluble guanylyl cyclase (sGC) by riociguat attenuates heart failure and pathological cardiac remodelling.

Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling.

Ruthenium 360 and mitoxantrone inhibit mitochondrial calcium uniporter channel to prevent liver steatosis induced by high‐fat diet.

The antibiotic drug trimethoprim suppresses tumour growth and metastasis via targeting Snail.

Genetic deletion or pharmacological blockade of nociceptin/orphanin FQ receptors in the ventral tegmental area attenuates nicotine‐motivated behaviour.

Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.

A new class of 5‐HT<sub>2A</sub>/5‐HT<sub>2C</sub> receptor inverse agonists: Synthesis, molecular modeling, in vitro and in vivo pharmacology of novel 2‐aminotetralins.

Moving in the right direction: elucidating the mechanisms of interaction between flecainide and the cardiac ryanodine receptor.

Multidrug resistance proteins preferentially regulate natriuretic peptide‐driven cGMP signalling in the heart and vasculature.

Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney.

Issue Information.

cGMP and mitochondrial K<sup>+</sup> channels—Compartmentalized but closely connected in cardioprotection.

Constitutive protein kinase G activation exacerbates stress‐induced cardiomyopathy.

Inactivation of soluble guanylyl cyclase in living cells proceeds without loss of haem and involves heterodimer dissociation as a common step.

Angiotensin II augments renal vascular smooth muscle soluble GC expression via an AT<sub>1</sub> receptor–forkhead box subclass O transcription factor signalling axis.

Visualising and understanding cGMP signals in the cardiovascular system.

The role of cGMP signalling in auditory processing in health and disease.

Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide‐gated channels.

Activation of soluble guanylyl cyclase signalling with cinaciguat improves impaired kidney function in diabetic mice.