Works matching IS 00071188 AND DT 2020 AND VI 177 AND IP 15

Results: 18

The many mechanisms of action of Chloroquine: to use or not to use (in COVID-19) that is the question.

Published in:

2020

By:

Cirino, Giuseppe;
Ahluwalia, Amrita

Publication type:

Editorial

Cyclic AMP in dendritic cells: A novel potential target for disease-modifying agents in asthma and other allergic disorders.

Published in:

2020

By:

Chinn, Amy M.;
Insel, Paul A.

Publication type:

journal article

Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in mice.

Published in:

2020

By:

Li, Xinwei;
Shi, Zhen;
Zhu, Yiwei;
Shen, Taiyu;
Wang, Heyuan;
Shui, Guanghou;
Loor, Juan J.;
Fang, Zhiyuan;
Chen, Meng;
Wang, Xinghui;
Peng, Zhicheng;
Song, Yuxiang;
Wang, Zhe;
Du, Xiliang;
Liu, Guowen

Publication type:

journal article

Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities.

Published in:

2020

By:

Venkatasubramanian, Raja;
Collins, Teresa A.;
Lesko, Lawrence J.;
Mettetal, Jerome T.;
Trame, Mirjam N.

Publication type:

journal article

Cloning and characterization of the rat Slo3 (KCa 5.1) channel: From biophysics to pharmacology.

Published in:

2020

By:

Wang, Guang‐Ming;
Zhong, Zhi‐Gang;
Du, Xiang‐Rong;
Zhang, Fei‐Fei;
Guo, Qing;
Liu, Ye;
Tang, Qiong‐Yao;
Zhang, Zhe;
Wang, Guang-Ming;
Zhong, Zhi-Gang;
Du, Xiang-Rong;
Zhang, Fei-Fei;
Tang, Qiong-Yao

Publication type:

journal article

B1 and B2 kinin receptor blockade improves psoriasis-like disease.

Published in:

2020

By:

Soley, Bruna da Silva;
Silva, Leonardo Martins;
Mendes, Daniel Augusto Gasparin Bueno;
Báfica, André;
Pesquero, João Bosco;
Bader, Michael;
Witherden, Deborah A.;
Havran, Wendy L.;
Calixto, João B.;
Otuki, Michel Fleith;
Cabrini, Daniela Almeida

Publication type:

journal article

Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility.

Published in:

2020

By:

Tang, Yangshun;
Feng, Bo;
Wang, Yi;
Sun, Huiyong;
You, Yi;
Yu, Jie;
Chen, Bin;
Xu, Cenglin;
Ruan, Yeping;
Cui, Sunliang;
Hu, Gang;
Hou, Tingjun;
Chen, Zhong

Publication type:

journal article

Heat shock protein 90 inhibition and multi-target approach to maximize cardioprotection in ischaemic injury.

Published in:

2020

By:

Der Sarkissian, Shant;
Aceros, Henry;
Williams, Pierre‐Marc;
Scalabrini, Catherine;
Borie, Mélanie;
Noiseux, Nicolas;
Williams, Pierre-Marc

Publication type:

journal article

Transcriptomic analysis of pulmonary artery smooth muscle cells identifies new potential therapeutic targets for idiopathic pulmonary arterial hypertension.

Published in:

2020

By:

Gorr, Matthew W.;
Sriram, Krishna;
Muthusamy, Abinaya;
Insel, Paul A.

Publication type:

journal article

Voltage modulates the effect of μ-receptor activation in a ligand-dependent manner.

Published in:

2020

By:

Ruland, Julia G.;
Kirchhofer, Sina B.;
Klindert, Sebastian;
Bailey, Chris P.;
Bünemann, Moritz

Publication type:

journal article

An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.

Published in:

British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3473, doi. 10.1111/bph.15069

By:

Lu, Weisheng;
Tian, Hong;
Qian, Peng;
Li, Ying;
Wang, Yongkang;
Ge, Yang;
Sai, Wenbo;
Gao, Xiangdong;
Yao, Wenbing

Publication type:

Article

Exploring occupancy of the histamine H3 receptor by pitolisant in humans using PET.

Published in:

British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3464, doi. 10.1111/bph.15067

By:

Rusjan, Pablo;
Sabioni, Pamela;
Di Ciano, Patricia;
Mansouri, Esmaeil;
Boileau, Isabelle;
Laveillé, Alexia;
Capet, Marc;
Duvauchelle, Thierry;
Schwartz, Jean‐Charles;
Robert, Philippe;
Le Foll, Bernard

Publication type:

Article

Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling.

Published in:

British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3449, doi. 10.1111/bph.15066

By:

Zhu, Xiao;
Finlay, David B.;
Glass, Michelle;
Duffull, Stephen B.

Publication type:

Article

Identification of endogenous 1-aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation.

Published in:

2020

By:

Miao, Hua;
Cao, Gang;
Wu, Xia‐Qing;
Chen, Yuan‐Yuan;
Chen, Dan‐Qian;
Chen, Lin;
Vaziri, Nosratola D.;
Feng, Ya‐Long;
Su, Wei;
Gao, Yi;
Zhuang, Shougang;
Yu, Xiao‐Yong;
Zhang, Li;
Guo, Yan;
Zhao, Ying‐Yong;
Wu, Xia-Qing;
Chen, Yuan-Yuan;
Chen, Dan-Qian;
Feng, Ya-Long;
Yu, Xiao-Yong

Publication type:

journal article

TAAR1 agonists attenuate extended-access cocaine self-administration and yohimbine-induced reinstatement of cocaine-seeking.

Published in:

2020

By:

Liu, Jianfeng;
Johnson, Bernard;
Wu, Ruyan;
Seaman, Robert;
Vu, Jimmy;
Zhu, Qing;
Zhang, Yanan;
Li, Jun‐Xu;
Seaman, Robert Jr;
Li, Jun-Xu

Publication type:

journal article

Exendin-4, a GLP-1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia-reperfusion injury.

Published in:

2020

By:

Zhai, Ruyi;
Xu, Huan;
Hu, Fangyuan;
Wu, Jihong;
Kong, Xiangmei;
Sun, Xinghuai

Publication type:

journal article

Issue Information.

Published in:: British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3359, doi. 10.1111/bph.14734
Publication type:: Article

Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.

Published in:

2020

By:

Baptista‐Hon, Daniel T.;
Smith, Mark;
Singleton, Samuel;
Antonides, Lysbeth H.;
Nic Daeid, Niamh;
McKenzie, Craig;
Hales, Tim G.;
Baptista-Hon, Daniel T

Publication type:

journal article

Works matching IS 00071188 AND DT 2020 AND VI 177 AND IP 15

The many mechanisms of action of Chloroquine: to use or not to use (in COVID-19) that is the question.

Cyclic AMP in dendritic cells: A novel potential target for disease-modifying agents in asthma and other allergic disorders.

Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in mice.

Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities.

Cloning and characterization of the rat Slo3 (K<sub>Ca</sub> 5.1) channel: From biophysics to pharmacology.

B<sub>1</sub> and B<sub>2</sub> kinin receptor blockade improves psoriasis-like disease.

Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility.

Heat shock protein 90 inhibition and multi-target approach to maximize cardioprotection in ischaemic injury.

Transcriptomic analysis of pulmonary artery smooth muscle cells identifies new potential therapeutic targets for idiopathic pulmonary arterial hypertension.

Voltage modulates the effect of μ-receptor activation in a ligand-dependent manner.

An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.

Exploring occupancy of the histamine H<sub>3</sub> receptor by pitolisant in humans using PET.

Evaluation of the profiles of CB<sub>1</sub> cannabinoid receptor signalling bias using joint kinetic modelling.

Identification of endogenous 1-aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation.

TAAR1 agonists attenuate extended-access cocaine self-administration and yohimbine-induced reinstatement of cocaine-seeking.

Exendin-4, a GLP-1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia-reperfusion injury.

Issue Information.

Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.