Works matching IS 00071188 AND DT 2020 AND VI 177 AND IP 15

Results: 18

Cyclic AMP in dendritic cells: A novel potential target for disease-modifying agents in asthma and other allergic disorders.
Published in:
2020
By:
- Chinn, Amy M.;
- Insel, Paul A.
Publication type:
journal article
Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities.
Published in:
2020
By:
- Venkatasubramanian, Raja;
- Collins, Teresa A.;
- Lesko, Lawrence J.;
- Mettetal, Jerome T.;
- Trame, Mirjam N.
Publication type:
journal article
The many mechanisms of action of Chloroquine: to use or not to use (in COVID-19) that is the question.
Published in:
2020
By:
- Cirino, Giuseppe;
- Ahluwalia, Amrita
Publication type:
Editorial
Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in mice.
Published in:
2020
By:
- Li, Xinwei;
- Shi, Zhen;
- Zhu, Yiwei;
- Shen, Taiyu;
- Wang, Heyuan;
- Shui, Guanghou;
- Loor, Juan J.;
- Fang, Zhiyuan;
- Chen, Meng;
- Wang, Xinghui;
- Peng, Zhicheng;
- Song, Yuxiang;
- Wang, Zhe;
- Du, Xiliang;
- Liu, Guowen
Publication type:
journal article
Cloning and characterization of the rat Slo3 (KCa 5.1) channel: From biophysics to pharmacology.
Published in:
2020
By:
- Wang, Guang‐Ming;
- Zhong, Zhi‐Gang;
- Du, Xiang‐Rong;
- Zhang, Fei‐Fei;
- Guo, Qing;
- Liu, Ye;
- Tang, Qiong‐Yao;
- Zhang, Zhe;
- Wang, Guang-Ming;
- Zhong, Zhi-Gang;
- Du, Xiang-Rong;
- Zhang, Fei-Fei;
- Tang, Qiong-Yao
Publication type:
journal article
B1 and B2 kinin receptor blockade improves psoriasis-like disease.
Published in:
2020
By:
- Soley, Bruna da Silva;
- Silva, Leonardo Martins;
- Mendes, Daniel Augusto Gasparin Bueno;
- Báfica, André;
- Pesquero, João Bosco;
- Bader, Michael;
- Witherden, Deborah A.;
- Havran, Wendy L.;
- Calixto, João B.;
- Otuki, Michel Fleith;
- Cabrini, Daniela Almeida
Publication type:
journal article
Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility.
Published in:
2020
By:
- Tang, Yangshun;
- Feng, Bo;
- Wang, Yi;
- Sun, Huiyong;
- You, Yi;
- Yu, Jie;
- Chen, Bin;
- Xu, Cenglin;
- Ruan, Yeping;
- Cui, Sunliang;
- Hu, Gang;
- Hou, Tingjun;
- Chen, Zhong
Publication type:
journal article
Heat shock protein 90 inhibition and multi-target approach to maximize cardioprotection in ischaemic injury.
Published in:
2020
By:
- Der Sarkissian, Shant;
- Aceros, Henry;
- Williams, Pierre‐Marc;
- Scalabrini, Catherine;
- Borie, Mélanie;
- Noiseux, Nicolas;
- Williams, Pierre-Marc
Publication type:
journal article
Transcriptomic analysis of pulmonary artery smooth muscle cells identifies new potential therapeutic targets for idiopathic pulmonary arterial hypertension.
Published in:
2020
By:
- Gorr, Matthew W.;
- Sriram, Krishna;
- Muthusamy, Abinaya;
- Insel, Paul A.
Publication type:
journal article
Identification of endogenous 1-aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation.
Published in:
2020
By:
- Miao, Hua;
- Cao, Gang;
- Wu, Xia‐Qing;
- Chen, Yuan‐Yuan;
- Chen, Dan‐Qian;
- Chen, Lin;
- Vaziri, Nosratola D.;
- Feng, Ya‐Long;
- Su, Wei;
- Gao, Yi;
- Zhuang, Shougang;
- Yu, Xiao‐Yong;
- Zhang, Li;
- Guo, Yan;
- Zhao, Ying‐Yong;
- Wu, Xia-Qing;
- Chen, Yuan-Yuan;
- Chen, Dan-Qian;
- Feng, Ya-Long;
- Yu, Xiao-Yong
Publication type:
journal article
An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.
Published in:
British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3473, doi. 10.1111/bph.15069
By:
- Lu, Weisheng;
- Tian, Hong;
- Qian, Peng;
- Li, Ying;
- Wang, Yongkang;
- Ge, Yang;
- Sai, Wenbo;
- Gao, Xiangdong;
- Yao, Wenbing
Publication type:
Article
Exploring occupancy of the histamine H3 receptor by pitolisant in humans using PET.
Published in:
British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3464, doi. 10.1111/bph.15067
By:
- Rusjan, Pablo;
- Sabioni, Pamela;
- Di Ciano, Patricia;
- Mansouri, Esmaeil;
- Boileau, Isabelle;
- Laveillé, Alexia;
- Capet, Marc;
- Duvauchelle, Thierry;
- Schwartz, Jean‐Charles;
- Robert, Philippe;
- Le Foll, Bernard
Publication type:
Article
Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling.
Published in:
British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3449, doi. 10.1111/bph.15066
By:
- Zhu, Xiao;
- Finlay, David B.;
- Glass, Michelle;
- Duffull, Stephen B.
Publication type:
Article
Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.
Published in:
2020
By:
- Baptista‐Hon, Daniel T.;
- Smith, Mark;
- Singleton, Samuel;
- Antonides, Lysbeth H.;
- Nic Daeid, Niamh;
- McKenzie, Craig;
- Hales, Tim G.;
- Baptista-Hon, Daniel T
Publication type:
journal article
Voltage modulates the effect of μ-receptor activation in a ligand-dependent manner.
Published in:
2020
By:
- Ruland, Julia G.;
- Kirchhofer, Sina B.;
- Klindert, Sebastian;
- Bailey, Chris P.;
- Bünemann, Moritz
Publication type:
journal article
TAAR1 agonists attenuate extended-access cocaine self-administration and yohimbine-induced reinstatement of cocaine-seeking.
Published in:
2020
By:
- Liu, Jianfeng;
- Johnson, Bernard;
- Wu, Ruyan;
- Seaman, Robert;
- Vu, Jimmy;
- Zhu, Qing;
- Zhang, Yanan;
- Li, Jun‐Xu;
- Seaman, Robert Jr;
- Li, Jun-Xu
Publication type:
journal article
Exendin-4, a GLP-1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia-reperfusion injury.
Published in:
2020
By:
- Zhai, Ruyi;
- Xu, Huan;
- Hu, Fangyuan;
- Wu, Jihong;
- Kong, Xiangmei;
- Sun, Xinghuai
Publication type:
journal article
Issue Information.
Published in:
British Journal of Pharmacology, 2020, v. 177, n. 15, p. 3359, doi. 10.1111/bph.14734
Publication type:
Article

Works matching IS 00071188 AND DT 2020 AND VI 177 AND IP 15

Cyclic AMP in dendritic cells: A novel potential target for disease-modifying agents in asthma and other allergic disorders.

Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities.

The many mechanisms of action of Chloroquine: to use or not to use (in COVID-19) that is the question.

Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in mice.

Cloning and characterization of the rat Slo3 (K<sub>Ca</sub> 5.1) channel: From biophysics to pharmacology.

B<sub>1</sub> and B<sub>2</sub> kinin receptor blockade improves psoriasis-like disease.

Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility.

Heat shock protein 90 inhibition and multi-target approach to maximize cardioprotection in ischaemic injury.

Transcriptomic analysis of pulmonary artery smooth muscle cells identifies new potential therapeutic targets for idiopathic pulmonary arterial hypertension.

Identification of endogenous 1-aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation.

An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.

Exploring occupancy of the histamine H<sub>3</sub> receptor by pitolisant in humans using PET.

Evaluation of the profiles of CB<sub>1</sub> cannabinoid receptor signalling bias using joint kinetic modelling.

Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.

Voltage modulates the effect of μ-receptor activation in a ligand-dependent manner.

TAAR1 agonists attenuate extended-access cocaine self-administration and yohimbine-induced reinstatement of cocaine-seeking.

Exendin-4, a GLP-1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia-reperfusion injury.

Issue Information.