Works matching IS 00071188 AND DT 2018 AND VI 175 AND IP 12

Results: 31

Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.
Published in:
2018
By:
- Brookes, Daniel W.;
- Coates, Matthew;
- Allen, Heather;
- Daly, Leah;
- Constant, Samuel;
- Huang, Song;
- Hows, Mark;
- Davis, Amanda;
- Cass, Lindsey;
- Ayrton, John;
- Knowles, Ian;
- Strong, Pete;
- Rapeport, Garth;
- Ito, Kazuhiro
Publication type:
journal article
Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.
Published in:
2018
By:
- Ozhathil, Lijo Cherian;
- Delalande, Clémence;
- Bianchi, Beatrice;
- Nemeth, Gabor;
- Kappel, Sven;
- Thomet, Urs;
- Ross‐Kaschitza, Daniela;
- Simonin, Céline;
- Rubin, Matthias;
- Gertsch, Jürg;
- Lochner, Martin;
- Peinelt, Christine;
- Reymond, Jean‐Louis;
- Abriel, Hugues;
- Ross-Kaschitza, Daniela;
- Reymond, Jean-Louis
Publication type:
journal article
Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.
Published in:
2018
By:
- Hill, Rob;
- Dewey, William L.;
- Kelly, Eamonn;
- Henderson, Graeme
Publication type:
journal article
P2Y12 receptor modulation of ADP-evoked intracellular Ca2+ signalling in THP-1 human monocytic cells.
Published in:
2018
By:
- Micklewright, J. J.;
- Layhadi, J. A.;
- Fountain, S. J.
Publication type:
journal article
Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.
Published in:
2018
By:
- Bossu, Alexandre;
- Houtman, Marien J. C.;
- Meijborg, Veronique M. F.;
- Varkevisser, Rosanne;
- Beekman, Henriette D. M.;
- Dunnink, Albert;
- de Bakker, Jacques M. T.;
- Mollova, Nevena;
- Rajamani, Sridharan;
- Belardinelli, Luiz;
- van der Heyden, Marcel A. G.;
- Vos, Marc A.
Publication type:
journal article
Recent advances in targeting ion channels to treat chronic pain.
Published in:
2018
By:
- Stevens, Edward B.;
- Stephens, Gary J.
Publication type:
Editorial
The non-biphenyl-tetrazole angiotensin AT1 receptor antagonist eprosartan is a unique and robust inverse agonist of the active state of the AT1 receptor.
Published in:
2018
By:
- Takezako, Takanobu;
- Unal, Hamiyet;
- Karnik, Sadashiva S.;
- Node, Koichi
Publication type:
journal article
Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control.
Published in:
2018
By:
- Kang, Jung‐Woo;
- Choi, Hyo‐Sun;
- Lee, Sun‐Mee;
- Kang, Jung-Woo;
- Choi, Hyo-Sun;
- Lee, Sun-Mee
Publication type:
journal article
Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine.
Published in:
2018
By:
- Carpéné, Christian;
- Mercader, Josep;
- Le Gonidec, Sophie;
- Schaak, Stéphane;
- Mialet‐Perez, Jeanne;
- Zakaroff‐Girard, Alexia;
- Galitzky, Jean;
- Mialet-Perez, Jeanne;
- Zakaroff-Girard, Alexia
Publication type:
journal article
Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.
Published in:
2018
By:
- Chiou, Lih‐Chu;
- Lee, Hsin‐Jung;
- Ernst, Margot;
- Huang, Wei‐Jan;
- Chou, Jui‐Feng;
- Chen, Hon‐Lie;
- Mouri, Akihiro;
- Chen, Liang‐Chieh;
- Treven, Marco;
- Mamiya, Takayoshi;
- Fan, Pi‐Chuan;
- Knutson, Daniel E.;
- Witzigmann, Chris;
- Cook, James;
- Sieghart, Werner;
- Nabeshima, Toshitaka;
- Chiou, Lih-Chu;
- Lee, Hsin-Jung;
- Huang, Wei-Jan;
- Chou, Jui-Feng
Publication type:
journal article
Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord.
Published in:
2018
By:
- Winters, Bryony L.;
- Rawling, Tristan;
- Vandenberg, Robert J.;
- Christie, Macdonald J.;
- Bhola, Rebecca F.;
- Imlach, Wendy L.
Publication type:
journal article
Gabapentin prevents synaptogenesis between sensory and spinal cord neurons induced by thrombospondin-4 acting on pre-synaptic Cav α2 δ1 subunits and involving T-type Ca2+ channels.
Published in:
2018
By:
- Yu, Yanhui Peter;
- Gong, Nian;
- Kweon, Tae Dong;
- Vo, Benjamin;
- Luo, Z. David
Publication type:
journal article
Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.
Published in:
2018
By:
- Castro, Joel;
- Grundy, Luke;
- Deiteren, Annemie;
- Harrington, Andrea M.;
- O'Donnell, Tracey;
- Maddern, Jessica;
- Moore, Jessi;
- Garcia‐Caraballo, Sonia;
- Rychkov, Grigori Y.;
- Yu, Rilei;
- Kaas, Quentin;
- Craik, David J.;
- Adams, David J.;
- Brierley, Stuart M.;
- O'Donnell, Tracey;
- Garcia-Caraballo, Sonia
Publication type:
journal article
GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.
Published in:
2018
By:
- Loucif, Alexandre J. C.;
- Saintot, Pierre‐Philippe;
- Liu, Jia;
- Antonio, Brett M.;
- Zellmer, Shannon G.;
- Yoger, Katrina;
- Veale, Emma L.;
- Wilbrey, Anna;
- Omoto, Kiyoyuki;
- Cao, Lishuang;
- Gutteridge, Alex;
- Castle, Neil A.;
- Stevens, Edward B.;
- Mathie, Alistair;
- Saintot, Pierre-Philippe
Publication type:
journal article
Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.
Published in:
2018
By:
- Lee, Jia Yu Peppermint;
- Saez, Natalie J.;
- Cristofori‐Armstrong, Ben;
- Anangi, Raveendra;
- King, Glenn F.;
- Smith, Maree T.;
- Rash, Lachlan D.;
- Cristofori-Armstrong, Ben
Publication type:
journal article
Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.
Published in:
2018
By:
- Moran, Magdalene M.;
- Szallasi, Arpad
Publication type:
journal article
Issue Information.
Published in:
British Journal of Pharmacology, 2018, v. 175, n. 12, p. 2131, doi. 10.1111/bph.14005
Publication type:
Article
M-type K+ channels in peripheral nociceptive pathways.
Published in:
2018
By:
- Du, Xiaona;
- Gao, Haixia;
- Jaffe, David;
- Zhang, Hailin;
- Gamper, Nikita
Publication type:
journal article
Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.
Published in:
2018
By:
- Tadesse, Solomon;
- Bantie, Laychiluh;
- Tomusange, Khamis;
- Yu, Mingfeng;
- Islam, Saiful;
- Bykovska, Nataliya;
- Noll, Benjamin;
- Zhu, Ge;
- Li, Peng;
- Lam, Frankie;
- Kumarasiri, Malika;
- Milne, Robert;
- Wang, Shudong
Publication type:
journal article
Sodium channels and pain: from toxins to therapies.
Published in:
2018
By:
- Cardoso, Fernanda C.;
- Lewis, Richard J.
Publication type:
journal article
P2X receptor channels in chronic pain pathways.
Published in:
2018
By:
- Bernier, Louis‐Philippe;
- Ase, Ariel R.;
- Séguéla, Philippe;
- Bernier, Louis-Philippe
Publication type:
journal article
Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T.
Published in:
2018
By:
- Yang, Yang;
- Adi, Talia;
- Effraim, Philip R.;
- Chen, Lubin;
- Dib‐Hajj, Sulayman D.;
- Waxman, Stephen G.;
- Dib-Hajj, Sulayman D
Publication type:
journal article
Injury-induced maladaptation and dysregulation of calcium channel α2 δ subunit proteins and its contribution to neuropathic pain development.
Published in:
2018
By:
- Gong, Nian;
- Park, John;
- Luo, Z. David
Publication type:
journal article
Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.
Published in:
2018
By:
- Mourot, Alexandre;
- Herold, Christian;
- Kienzler, Michael A.;
- Kramer, Richard H.
Publication type:
journal article
Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.
Published in:
2018
By:
- Bell, Damian C.;
- Dallas, Mark L.
Publication type:
journal article
Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1.
Published in:
2018
By:
- McArthur, Jeffrey R.;
- Motin, Leonid;
- Gleeson, Ellen C.;
- Spiller, Sandro;
- Lewis, Richard J.;
- Duggan, Peter J.;
- Tuck, Kellie L.;
- Adams, David J.
Publication type:
journal article
Recent advances in the development of T-type calcium channel blockers for pain intervention.
Published in:
2018
By:
- Snutch, Terrance P.;
- Zamponi, Gerald W.
Publication type:
journal article
Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N-arachidonoylphosphatidylethanolamine.
Published in:
2018
By:
- Nerandzic, Vladimir;
- Mrozkova, Petra;
- Adamek, Pavel;
- Spicarova, Diana;
- Nagy, Istvan;
- Palecek, Jiri
Publication type:
journal article
Calcium channel modulation as a target in chronic pain control.
Published in:
2018
By:
- Patel, Ryan;
- Montagut‐Bordas, Carlota;
- Dickenson, Anthony H.;
- Montagut-Bordas, Carlota
Publication type:
journal article
Calcium signalling through L-type calcium channels: role in pathophysiology of spinal nociceptive transmission.
Published in:
2018
By:
- Roca‐Lapirot, Olivier;
- Radwani, Houda;
- Aby, Franck;
- Nagy, Frédéric;
- Landry, Marc;
- Fossat, Pascal;
- Roca-Lapirot, Olivier
Publication type:
journal article
Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.
Published in:
2018
By:
- Moutal, Aubin;
- Li, Wennan;
- Wang, Yue;
- Ju, Weina;
- Luo, Shizhen;
- Cai, Song;
- François‐Moutal, Liberty;
- Perez‐Miller, Samantha;
- Hu, Jackie;
- Dustrude, Erik T.;
- Vanderah, Todd W.;
- Gokhale, Vijay;
- Khanna, May;
- Khanna, Rajesh;
- François-Moutal, Liberty;
- Perez-Miller, Samantha
Publication type:
journal article

Works matching IS 00071188 AND DT 2018 AND VI 175 AND IP 12

Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.

Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.

Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.

P2Y<sub>12</sub> receptor modulation of ADP-evoked intracellular Ca<sup>2+</sup> signalling in THP-1 human monocytic cells.

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.

Recent advances in targeting ion channels to treat chronic pain.

The non-biphenyl-tetrazole angiotensin AT<sub>1</sub> receptor antagonist eprosartan is a unique and robust inverse agonist of the active state of the AT<sub>1</sub> receptor.

Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control.

Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine.

Cerebellar α<sub>6</sub> -subunit-containing GABA<sub>A</sub> receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.

Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord.

Gabapentin prevents synaptogenesis between sensory and spinal cord neurons induced by thrombospondin-4 acting on pre-synaptic Ca<sub>v</sub> α<sub>2</sub> δ<sub>1</sub> subunits and involving T-type Ca<sup>2+</sup> channels.

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.

GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K<sub>2P</sub> ) channel opener, reduces rat dorsal root ganglion neuron excitability.

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.

Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.

Issue Information.

M-type K<sup>+</sup> channels in peripheral nociceptive pathways.

Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.

Sodium channels and pain: from toxins to therapies.

P2X receptor channels in chronic pain pathways.

Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Na<sub>v</sub> 1.7 mutation I234T.

Injury-induced maladaptation and dysregulation of calcium channel α<sub>2</sub> δ subunit proteins and its contribution to neuropathic pain development.

Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.

Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.

Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1.

Recent advances in the development of T-type calcium channel blockers for pain intervention.

Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N-arachidonoylphosphatidylethanolamine.

Calcium channel modulation as a target in chronic pain control.

Calcium signalling through L-type calcium channels: role in pathophysiology of spinal nociceptive transmission.

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.