Works matching IS 00071188 AND DT 2018 AND VI 175 AND IP 12

Results: 31

Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.

Published in:

2018

By:

Brookes, Daniel W.;
Coates, Matthew;
Allen, Heather;
Daly, Leah;
Constant, Samuel;
Huang, Song;
Hows, Mark;
Davis, Amanda;
Cass, Lindsey;
Ayrton, John;
Knowles, Ian;
Strong, Pete;
Rapeport, Garth;
Ito, Kazuhiro

Publication type:

journal article

The non-biphenyl-tetrazole angiotensin AT1 receptor antagonist eprosartan is a unique and robust inverse agonist of the active state of the AT1 receptor.

Published in:

2018

By:

Takezako, Takanobu;
Unal, Hamiyet;
Karnik, Sadashiva S.;
Node, Koichi

Publication type:

journal article

Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.

Published in:

2018

By:

Hill, Rob;
Dewey, William L.;
Kelly, Eamonn;
Henderson, Graeme

Publication type:

journal article

P2Y12 receptor modulation of ADP-evoked intracellular Ca2+ signalling in THP-1 human monocytic cells.

Published in:

2018

By:

Micklewright, J. J.;
Layhadi, J. A.;
Fountain, S. J.

Publication type:

journal article

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.

Published in:

2018

By:

Bossu, Alexandre;
Houtman, Marien J. C.;
Meijborg, Veronique M. F.;
Varkevisser, Rosanne;
Beekman, Henriette D. M.;
Dunnink, Albert;
de Bakker, Jacques M. T.;
Mollova, Nevena;
Rajamani, Sridharan;
Belardinelli, Luiz;
van der Heyden, Marcel A. G.;
Vos, Marc A.

Publication type:

journal article

Recent advances in targeting ion channels to treat chronic pain.

Published in:

2018

By:

Stevens, Edward B.;
Stephens, Gary J.

Publication type:

Editorial

Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.

Published in:

2018

By:

Ozhathil, Lijo Cherian;
Delalande, Clémence;
Bianchi, Beatrice;
Nemeth, Gabor;
Kappel, Sven;
Thomet, Urs;
Ross‐Kaschitza, Daniela;
Simonin, Céline;
Rubin, Matthias;
Gertsch, Jürg;
Lochner, Martin;
Peinelt, Christine;
Reymond, Jean‐Louis;
Abriel, Hugues;
Ross-Kaschitza, Daniela;
Reymond, Jean-Louis

Publication type:

journal article

Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control.

Published in:

2018

By:

Kang, Jung‐Woo;
Choi, Hyo‐Sun;
Lee, Sun‐Mee;
Kang, Jung-Woo;
Choi, Hyo-Sun;
Lee, Sun-Mee

Publication type:

journal article

Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine.

Published in:

2018

By:

Carpéné, Christian;
Mercader, Josep;
Le Gonidec, Sophie;
Schaak, Stéphane;
Mialet‐Perez, Jeanne;
Zakaroff‐Girard, Alexia;
Galitzky, Jean;
Mialet-Perez, Jeanne;
Zakaroff-Girard, Alexia

Publication type:

journal article

Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.

Published in:

2018

By:

Chiou, Lih‐Chu;
Lee, Hsin‐Jung;
Ernst, Margot;
Huang, Wei‐Jan;
Chou, Jui‐Feng;
Chen, Hon‐Lie;
Mouri, Akihiro;
Chen, Liang‐Chieh;
Treven, Marco;
Mamiya, Takayoshi;
Fan, Pi‐Chuan;
Knutson, Daniel E.;
Witzigmann, Chris;
Cook, James;
Sieghart, Werner;
Nabeshima, Toshitaka;
Chiou, Lih-Chu;
Lee, Hsin-Jung;
Huang, Wei-Jan;
Chou, Jui-Feng

Publication type:

journal article

Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord.

Published in:

2018

By:

Winters, Bryony L.;
Rawling, Tristan;
Vandenberg, Robert J.;
Christie, Macdonald J.;
Bhola, Rebecca F.;
Imlach, Wendy L.

Publication type:

journal article

Gabapentin prevents synaptogenesis between sensory and spinal cord neurons induced by thrombospondin-4 acting on pre-synaptic Cav α2 δ1 subunits and involving T-type Ca2+ channels.

Published in:

2018

By:

Yu, Yanhui Peter;
Gong, Nian;
Kweon, Tae Dong;
Vo, Benjamin;
Luo, Z. David

Publication type:

journal article

Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.

Published in:

2018

By:

Tadesse, Solomon;
Bantie, Laychiluh;
Tomusange, Khamis;
Yu, Mingfeng;
Islam, Saiful;
Bykovska, Nataliya;
Noll, Benjamin;
Zhu, Ge;
Li, Peng;
Lam, Frankie;
Kumarasiri, Malika;
Milne, Robert;
Wang, Shudong

Publication type:

journal article

Sodium channels and pain: from toxins to therapies.

Published in:

2018

By:

Cardoso, Fernanda C.;
Lewis, Richard J.

Publication type:

journal article

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.

Published in:

2018

By:

Castro, Joel;
Grundy, Luke;
Deiteren, Annemie;
Harrington, Andrea M.;
O'Donnell, Tracey;
Maddern, Jessica;
Moore, Jessi;
Garcia‐Caraballo, Sonia;
Rychkov, Grigori Y.;
Yu, Rilei;
Kaas, Quentin;
Craik, David J.;
Adams, David J.;
Brierley, Stuart M.;
O'Donnell, Tracey;
Garcia-Caraballo, Sonia

Publication type:

journal article

Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.

Published in:

2018

By:

Moran, Magdalene M.;
Szallasi, Arpad

Publication type:

journal article

Issue Information.

Published in:: British Journal of Pharmacology, 2018, v. 175, n. 12, p. 2131, doi. 10.1111/bph.14005
Publication type:: Article

M-type K+ channels in peripheral nociceptive pathways.

Published in:

2018

By:

Du, Xiaona;
Gao, Haixia;
Jaffe, David;
Zhang, Hailin;
Gamper, Nikita

Publication type:

journal article

GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.

Published in:

2018

By:

Loucif, Alexandre J. C.;
Saintot, Pierre‐Philippe;
Liu, Jia;
Antonio, Brett M.;
Zellmer, Shannon G.;
Yoger, Katrina;
Veale, Emma L.;
Wilbrey, Anna;
Omoto, Kiyoyuki;
Cao, Lishuang;
Gutteridge, Alex;
Castle, Neil A.;
Stevens, Edward B.;
Mathie, Alistair;
Saintot, Pierre-Philippe

Publication type:

journal article

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.

Published in:

2018

By:

Lee, Jia Yu Peppermint;
Saez, Natalie J.;
Cristofori‐Armstrong, Ben;
Anangi, Raveendra;
King, Glenn F.;
Smith, Maree T.;
Rash, Lachlan D.;
Cristofori-Armstrong, Ben

Publication type:

journal article

P2X receptor channels in chronic pain pathways.

Published in:

2018

By:

Bernier, Louis‐Philippe;
Ase, Ariel R.;
Séguéla, Philippe;
Bernier, Louis-Philippe

Publication type:

journal article

Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T.

Published in:

2018

By:

Yang, Yang;
Adi, Talia;
Effraim, Philip R.;
Chen, Lubin;
Dib‐Hajj, Sulayman D.;
Waxman, Stephen G.;
Dib-Hajj, Sulayman D

Publication type:

journal article

Injury-induced maladaptation and dysregulation of calcium channel α2 δ subunit proteins and its contribution to neuropathic pain development.

Published in:

2018

By:

Gong, Nian;
Park, John;
Luo, Z. David

Publication type:

journal article

Calcium channel modulation as a target in chronic pain control.

Published in:

2018

By:

Patel, Ryan;
Montagut‐Bordas, Carlota;
Dickenson, Anthony H.;
Montagut-Bordas, Carlota

Publication type:

journal article

Calcium signalling through L-type calcium channels: role in pathophysiology of spinal nociceptive transmission.

Published in:

2018

By:

Roca‐Lapirot, Olivier;
Radwani, Houda;
Aby, Franck;
Nagy, Frédéric;
Landry, Marc;
Fossat, Pascal;
Roca-Lapirot, Olivier

Publication type:

journal article

Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.

Published in:

2018

By:

Mourot, Alexandre;
Herold, Christian;
Kienzler, Michael A.;
Kramer, Richard H.

Publication type:

journal article

Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.

Published in:

2018

By:

Bell, Damian C.;
Dallas, Mark L.

Publication type:

journal article

Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1.

Published in:

2018

By:

McArthur, Jeffrey R.;
Motin, Leonid;
Gleeson, Ellen C.;
Spiller, Sandro;
Lewis, Richard J.;
Duggan, Peter J.;
Tuck, Kellie L.;
Adams, David J.

Publication type:

journal article

Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N-arachidonoylphosphatidylethanolamine.

Published in:

2018

By:

Nerandzic, Vladimir;
Mrozkova, Petra;
Adamek, Pavel;
Spicarova, Diana;
Nagy, Istvan;
Palecek, Jiri

Publication type:

journal article

Recent advances in the development of T-type calcium channel blockers for pain intervention.

Published in:

2018

By:

Snutch, Terrance P.;
Zamponi, Gerald W.

Publication type:

journal article

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

Published in:

2018

By:

Moutal, Aubin;
Li, Wennan;
Wang, Yue;
Ju, Weina;
Luo, Shizhen;
Cai, Song;
François‐Moutal, Liberty;
Perez‐Miller, Samantha;
Hu, Jackie;
Dustrude, Erik T.;
Vanderah, Todd W.;
Gokhale, Vijay;
Khanna, May;
Khanna, Rajesh;
François-Moutal, Liberty;
Perez-Miller, Samantha

Publication type:

journal article

Works matching IS 00071188 AND DT 2018 AND VI 175 AND IP 12

Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.

The non-biphenyl-tetrazole angiotensin AT<sub>1</sub> receptor antagonist eprosartan is a unique and robust inverse agonist of the active state of the AT<sub>1</sub> receptor.

Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.

P2Y<sub>12</sub> receptor modulation of ADP-evoked intracellular Ca<sup>2+</sup> signalling in THP-1 human monocytic cells.

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.

Recent advances in targeting ion channels to treat chronic pain.

Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.

Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control.

Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine.

Cerebellar α<sub>6</sub> -subunit-containing GABA<sub>A</sub> receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.

Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord.

Gabapentin prevents synaptogenesis between sensory and spinal cord neurons induced by thrombospondin-4 acting on pre-synaptic Ca<sub>v</sub> α<sub>2</sub> δ<sub>1</sub> subunits and involving T-type Ca<sup>2+</sup> channels.

Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.

Sodium channels and pain: from toxins to therapies.

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.

Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.

Issue Information.

M-type K<sup>+</sup> channels in peripheral nociceptive pathways.

GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K<sub>2P</sub> ) channel opener, reduces rat dorsal root ganglion neuron excitability.

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.

P2X receptor channels in chronic pain pathways.

Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Na<sub>v</sub> 1.7 mutation I234T.

Injury-induced maladaptation and dysregulation of calcium channel α<sub>2</sub> δ subunit proteins and its contribution to neuropathic pain development.

Calcium channel modulation as a target in chronic pain control.

Calcium signalling through L-type calcium channels: role in pathophysiology of spinal nociceptive transmission.

Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.

Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.

Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1.

Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N-arachidonoylphosphatidylethanolamine.

Recent advances in the development of T-type calcium channel blockers for pain intervention.

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.