Works matching IS 00071188 AND DT 2017 AND VI 174

Results: 410

Shikonin inhibits myeloid differentiation protein 2 to prevent LPS-induced acute lung injury.

Published in:

2017

By:

Zhang, Yali;
Xu, Tingting;
Pan, Zheer;
Ge, Xiangting;
Sun, Chuchu;
Lu, Chun;
Chen, Hongjin;
Xiao, Zhongxiang;
Zhang, Bing;
Dai, Yuanrong;
Liang, Guang

Publication type:

journal article

Finding the needle in the haystack: systematic identification of psychobiotics.

Published in:

2017

By:

Bambury, Aisling;
Sandhu, Kiran;
Cryan, John F;
Dinan, Timothy G

Publication type:

journal article

Mirabegron: potential off target effects and uses beyond the bladder.

Published in:

2017

By:

Dehvari, Nodi;
da Silva Junior, Edilson Dantas;
Bengtsson, Tore;
Hutchinson, Dana S;
Hutchinson, Dana Sabine

Publication type:

journal article

No pain, no gain: balancing central versus peripheral benefits of analgesics in the age of the opioid crisis.

Published in:

2017

By:

Patel, Hemal H;
Roth, David M

Publication type:

journal article

VPAC1 and VPAC2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways.

Published in:

2017

By:

Cunha‐Reis, Diana;
Ribeiro, Joaquim Alexandre;
Almeida, Rodrigo F M;
Sebastião, Ana M;
Cunha-Reis, Diana;
de Almeida, Rodrigo F M;
Sebastião, Ana M

Publication type:

journal article

BIO 300, a nanosuspension of genistein, mitigates pneumonitis/fibrosis following high-dose radiation exposure in the C57L/J murine model.

Published in:

2017

By:

Jackson, Isabel L;
Zodda, Andrew;
Gurung, Ganga;
Pavlovic, Radmila;
Kaytor, Michael D;
Kuskowski, Michael A;
Vujaskovic, Zeljko

Publication type:

journal article

Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.

Published in:

2017

By:

Han, Xiao;
Li, Bin;
Ye, Xin;
Mulatibieke, Tunike;
Wu, Jianghong;
Dai, Juanjuan;
Wu, Deqing;
Ni, Jianbo;
Zhang, Ruling;
Xue, Jing;
Wan, Rong;
Wang, Xingpeng;
Hu, Guoyong

Publication type:

journal article

Chronic treatment with novel nanoformulated micelles of rapamycin, Rapatar, protects diabetic heart against ischaemia/reperfusion injury.

Published in:

British Journal of Pharmacology, 2017, v. 174, n. 24, p. 4771, doi. 10.1111/bph.14059

By:

Samidurai, Arun;
Salloum, Fadi N;
Durrant, David;
Chernova, Olga B;
Kukreja, Rakesh C;
Das, Anindita

Publication type:

Article

Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease.

Published in:

2017

By:

Toledo, Enrique M;
Gyllborg, Daniel;
Arenas, Ernest

Publication type:

journal article

WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancer.

Published in:

2017

By:

Driehuis, Else;
Clevers, Hans

Publication type:

journal article

Wnt signalling pathways in chronic lymphocytic leukaemia and B-cell lymphomas.

Published in:

2017

By:

Janovská, Pavlína;
Bryja, Vítězslav;
Janovská, Pavlína;
Bryja, Vítězslav

Publication type:

journal article

Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers.

Published in:

British Journal of Pharmacology, 2017, v. 174, n. 24, p. 4666, doi. 10.1111/bph.13890

By:

Flanagan, Dustin J;
Vincan, Elizabeth;
Phesse, Toby J

Publication type:

Article

Rationale for targeting the Wnt signalling modulator Dickkopf-1 for oncology.

Published in:

2017

By:

Kagey, Michael H;
He, Xi

Publication type:

journal article

Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy.

Published in:

2017

By:

Lyou, Yung;
Habowski, Amber N;
Chen, George T;
Waterman, Marian L

Publication type:

journal article

Issue Information.

Published in:: British Journal of Pharmacology, 2017, v. 174, n. 24, p. 4541, doi. 10.1111/bph.13607
Publication type:: Article

Assembly and architecture of the Wnt/β-catenin signalosome at the membrane.

Published in:

2017

By:

DeBruine, Zachary J;
Xu, H E;
Melcher, Karsten

Publication type:

journal article

Correction.

Published in:: 2017
Publication type:: journal article

The Dickkopf1-cytoskeleton-associated protein 4 axis creates a novel signalling pathway and may represent a molecular target for cancer therapy.

Published in:

2017

By:

Kikuchi, Akira;
Fumoto, Katsumi;
Kimura, Hirokazu

Publication type:

journal article

Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein-protein interfaces of nuclear factors.

Published in:

2017

By:

Zimmerli, Dario;
Hausmann, George;
Cantù, Claudio;
Basler, Konrad;
Cantù, Claudio

Publication type:

journal article

Immuno-pharmacological characterization of group II metabotropic glutamate receptors controlling glutamate exocytosis in mouse cortex and spinal cord.

Published in:

British Journal of Pharmacology, 2017, v. 174, n. 24, p. 4785, doi. 10.1111/bph.14061

By:

Olivero, Guendalina;
Bonfiglio, Tommaso;
Vergassola, Matteo;
Usai, Cesare;
Riozzi, Barbara;
Battaglia, Giuseppe;
Nicoletti, Ferdinando;
Pittaluga, Anna

Publication type:

Article

Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.

Published in:

2017

By:

Jensen, Brian C;
Parry, Traci L;
Huang, Wei;
Beak, Ju Youn;
Ilaiwy, Amro;
Bain, James R;
Newgard, Christopher B;
Muehlbauer, Michael J;
Patterson, Cam;
Johnson, Gary L;
Willis, Monte S

Publication type:

journal article

Characterization of a rat model of bortezomib-induced painful neuropathy.

Published in:

2017

By:

Duggett, Natalie A;
Flatters, Sarah J L

Publication type:

journal article

Transient receptor potential vanilloid 1 inhibitors block laparotomy- and opioid-induced infarct size reduction in rats.

Published in:

2017

By:

Heymann, Helen M;
Wu, Yun;
Lu, Yao;
Qvit, Nir;
Gross, Garrett J;
Gross, Eric R

Publication type:

journal article

WNT signalling: mechanisms and therapeutic opportunities.

Published in:

2017

By:

Schulte, Gunnar;
Bryja, Vitezslav

Publication type:

Editorial

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes.

Published in:

2017

By:

Alexander, Stephen PH;
Fabbro, Doriano;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.

Published in:

2017

By:

Mariotti, Laura;
Pollock, Katie;
Guettler, Sebastian

Publication type:

journal article

Molecular regulation and pharmacological targeting of the β-catenin destruction complex.

Published in:

2017

By:

Kappel, Eline C;
Maurice, Madelon M;
van Kappel, Eline C

Publication type:

journal article

Characterization of the properties of a selective, orally bioavailable autotaxin inhibitor in preclinical models of advanced stages of liver fibrosis.

Published in:

2017

By:

Baader, Manuel;
Bretschneider, Tom;
Broermann, Andre;
Rippmann, Joerg F;
Stierstorfer, Birgit;
Kuttruff, Christian A;
Mark, Michael

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors.

Published in:

2017

By:

Alexander, Stephen PH;
Fabbro, Doriano;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

Published in:

2017

By:

Ong, Mei S;
Cai, Wanpei;
Yuan, Yi;
Leong, Hin C;
Tan, Tuan Z;
Mohammad, Asad;
You, Ming L;
Arfuso, Frank;
Goh, Boon C;
Warrier, Sudha;
Sethi, Gautam;
Tolwinski, Nicholas S;
Lobie, Peter E;
Yap, Celestial T;
Hooi, Shing C;
Huang, Ruby Y;
Kumar, Alan P

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors.

Published in:

2017

By:

Alexander, Stephen PH;
Christopoulos, Arthur;
Davenport, Anthony P;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels.

Published in:

2017

By:

Alexander, Stephen PH;
Peters, John A;
Kelly, Eamonn;
Marrion, Neil V;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

Issue Information.

Published in:: British Journal of Pharmacology, 2017, v. 174, p. i, doi. 10.1111/bph.13987
Publication type:: Article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors.

Published in:

2017

By:

Alexander, Stephen PH;
Cidlowski, John A;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Other ion channels.

Published in:

2017

By:

Alexander, Stephen PH;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.

Published in:

2017

By:

Alexander, Stephen PH;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Buneman, O Peter;
Cidlowski, John A;
Christopoulos, Arthur;
Davenport, Anthony P;
Fabbro, Doriano;
Spedding, Michael;
Striessnig, Jörg;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.

Published in:

2017

By:

Brusco, Indiara;
Camponogara, Camila;
Carvalho, Fabiano Barbosa;
Schetinger, Maria Rosa Chitolina;
Oliveira, Mauro Schneider;
Trevisan, Gabriela;
Ferreira, Juliano;
Oliveira, Sara Marchesan

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels.

Published in:

2017

By:

Alexander, Stephen PH;
Striessnig, Jörg;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

Induction of mast cell accumulation by chymase via an enzymatic activity- and intercellular adhesion molecule-1-dependent mechanism.

Published in:

2017

By:

Zhang, Huiyun;
Wang, Junling;
Wang, Ling;
Zhan, Mengmeng;
Li, Shigang;
Fang, Zeman;
Xu, Ciyan;
Zheng, Yanshan;
He, Shaoheng

Publication type:

journal article

Beyond symptomatic effects: potential of donepezil as a neuroprotective agent and disease modifier in Alzheimer's disease.

Published in:

2017

By:

Kim, Seung Hyun;
Kandiah, Nagaendran;
Hsu, Jung‐Lung;
Suthisisang, Chuthamanee;
Udommongkol, Chesda;
Dash, Amitabh;
Hsu, Jung-Lung

Publication type:

journal article

The monoacylglycerol lipase inhibitor KML29 with gabapentin synergistically produces analgesia in mice.

Published in:

2017

By:

Crowe, Molly S;
Wilson, Catheryn D;
Leishman, Emma;
Prather, Paul L;
Bradshaw, Heather B;
Banks, Matthew L;
Kinsey, Steven G

Publication type:

journal article

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters.

Published in:

2017

By:

Alexander, Stephen PH;
Kelly, Eamonn;
Marrion, Neil V;
Peters, John A;
Faccenda, Elena;
Harding, Simon D;
Pawson, Adam J;
Sharman, Joanna L;
Southan, Christopher;
Davies, Jamie A;
CGTP Collaborators

Publication type:

journal article

Principles of pharmacology in the eye.

Published in:

2017

By:

Awwad, Sahar;
Mohamed Ahmed, Abeer H A;
Sharma, Garima;
Heng, Jacob S;
Khaw, Peng T;
Brocchini, Steve;
Lockwood, Alastair

Publication type:

journal article

Selective targeting of M-type potassium Kv 7.4 channels demonstrates their key role in the regulation of dopaminergic neuronal excitability and depression-like behaviour.

Published in:

2017

By:

Li, Li;
Sun, Hui;
Ding, Jie;
Niu, Chenxu;
Su, Min;
Zhang, Ludi;
Li, Yingmin;
Wang, Chuan;
Gamper, Nikita;
Du, Xiaona;
Zhang, Hailin

Publication type:

journal article

Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.

Published in:

2017

By:

Hupp, Sabrina;
Ribes, Sandra;
Seele, Jana;
Bischoff, Carolin;
Förtsch, Christina;
Maier, Elke;
Benz, Roland;
Mitchell, Timothy J;
Nau, Roland;
Iliev, Asparouh I;
Förtsch, Christina

Publication type:

journal article

Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.

Published in:

2017

By:

Liu, Ting;
Zhang, Zhenxing;
Yu, Chunjie;
Zeng, Chang;
Xu, Xiaoqing;
Wu, Guixian;
Huang, Zan;
Li, Wenhua

Publication type:

journal article

Activation of G protein-coupled oestrogen receptor 1 at the onset of reperfusion protects the myocardium against ischemia/reperfusion injury by reducing mitochondrial dysfunction and mitophagy.

Published in:

2017

By:

Feng, Yansheng;
Madungwe, Ngonidzashe B;
Cruz Junho, Carolina Victoria;
Bopassa, Jean C;
da Cruz Junho, Carolina Victoria

Publication type:

journal article

p53-mediated regulation of bile acid disposition attenuates cholic acid-induced cholestasis in mice.

Published in:

2017

By:

Chen, Pan;
Li, Dongshun;
Chen, Yixin;
Sun, Jiahong;
Fu, Kaili;
Guan, Lihuan;
Zhang, Huizhen;
Jiang, Yiming;
Li, Xi;
Zeng, Xuezhen;
Chen, Xiao;
Huang, Min;
Bi, Huichang

Publication type:

journal article

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.

Published in:

2017

By:

Benson, Helen E;
Watterson, Steven;
Sharman, Joanna L;
Mpamhanga, Chido P;
Parton, Andrew;
Southan, Christopher;
Harmar, Anthony J;
Ghazal, Peter

Publication type:

journal article

Synthetic peptides designed to modulate adiponectin assembly improve obesity-related metabolic disorders.

Published in:

2017

By:

Hampe, Lutz;
Xu, Cheng;
Harris, Paul W R;
Chen, Jie;
Liu, Ming;
Middleditch, Martin;
Radjainia, Mazdak;
Wang, Yu;
Mitra, Alok K

Publication type:

journal article