Works matching IS 00071188 AND DT 2016 AND VI 173 AND IP 3

Results: 19

Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding.

Published in:

2016

By:

Song, Ting;
Chai, Gaobo;
Liu, Yubo;
Yu, Xiaoyan;
Wang, Ziqian;
Zhang, Zhichao

Publication type:

journal article

Enhanced serelaxin signalling in co-cultures of human primary endothelial and smooth muscle cells.

Published in:

2016

By:

Sarwar, M;
Samuel, C S;
Bathgate, R A;
Stewart, D R;
Summers, R J

Publication type:

journal article

Erratum.

Published in:: 2016
Publication type:: corrected article

How β3 -adrenoceptor-selective is mirabegron?

Published in:

2016

By:

Michel, Martin C

Publication type:

journal article

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222.

Published in:

2016

By:

Doornbos, Maarten L J;
Pérez ‐ Benito, Laura;
Tresadern, Gary;
Mulder ‐ Krieger, Thea;
Biesmans, Ilse;
Trabanco, Andrés A;
Cid, Jose María;
Lavreysen, Hilde;
IJzerman, Adriaan P;
Heitman, Laura H;
Pérez-Benito, Laura;
Mulder-Krieger, Thea;
Trabanco, Andrés A;
Cid, Jose María

Publication type:

journal article

The high frequency relationship: implications for torsadogenic hERG blockers.

Published in:

2016

By:

Champeroux, P;
Le Guennec, J Y;
Jude, S;
Laigot, C;
Maurin, A;
Sola, M L;
Fowler, J S L;
Richard, S;
Thireau, J

Publication type:

journal article

Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker.

Published in:

2016

By:

Ta, Chau M;
Adomaviciene, Aiste;
Rorsman, Nils J G;
Garnett, Hannah;
Tammaro, Paolo

Publication type:

journal article

Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier.

Published in:

2016

By:

Chapy, Hélène;
Saubaméa, Bruno;
Tournier, Nicolas;
Bourasset, Fanchon;
Behar ‐ Cohen, Francine;
Declèves, Xavier;
Scherrmann, Jean ‐ Michel;
Cisternino, Salvatore;
Chapy, Hélène;
Saubaméa, Bruno;
Behar-Cohen, Francine;
Declèves, Xavier;
Scherrmann, Jean-Michel

Publication type:

journal article

Issue Information.

Published in:: British Journal of Pharmacology, 2016, v. 173, n. 3, p. 413, doi. 10.1111/bph.13290
Publication type:: Article

Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX-770 (ivacaftor).

Published in:

2016

By:

Matthes, Elizabeth;
Goepp, Julie;
Carlile, Graeme W;
Luo, Yishan;
Dejgaard, Kurt;
Billet, Arnaud;
Robert, Renaud;
Thomas, David Y;
Hanrahan, John W

Publication type:

journal article

Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β3 -adrenoceptor activation and α1 -adrenoceptor blockade.

Published in:

2016

By:

Alexandre, E C;
Kiguti, L R;
Calmasini, F B;
Silva, F H;
Silva, K P;
Ferreira, R;
Ribeiro, C A;
Mónica, F Z;
Pupo, A S;
Antunes, E;
da Silva, K P;
Mónica, F Z

Publication type:

journal article

NVP-TAE684 reverses multidrug resistance (MDR) in human osteosarcoma by inhibiting P-glycoprotein (PGP1) function.

Published in:

2016

By:

Ye, Shunan;
Zhang, Jianming;
Shen, Jacson;
Gao, Yan;
Li, Ying;
Choy, Edwin;
Cote, Gregory;
Harmon, David;
Mankin, Henry;
Gray, Nathanael S;
Hornicek, Francis J;
Duan, Zhenfeng

Publication type:

journal article

Threonine532 phosphorylation in ClC-3 channels is required for angiotensin II-induced Cl(-) current and migration in cultured vascular smooth muscle cells.

Published in:

2016

By:

Ma, Ming ‐ Ming;
Lin, Cai ‐ Xia;
Liu, Can ‐ Zhao;
Gao, Min;
Sun, Lu;
Tang, Yong ‐ Bo;
Zhou, Jia ‐ Guo;
Wang, Guan ‐ Lei;
Guan, Yong ‐ Yuan;
Ma, Ming-Ming;
Lin, Cai-Xia;
Liu, Can-Zhao;
Tang, Yong-Bo;
Zhou, Jia-Guo;
Wang, Guan-Lei;
Guan, Yong-Yuan

Publication type:

journal article

Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1.

Published in:

2016

By:

Chen, Jing;
Lai, Jinsheng;
Yang, Lei;
Ruan, Guoran;
Chaugai, Sandip;
Ning, Qin;
Chen, Chen;
Wang, Dao Wen

Publication type:

journal article

Natural and synthetic flavonoid modulation of TRPC5 channels.

Published in:

2016

By:

Naylor, Jacqueline;
Minard, Aisling;
Gaunt, Hannah J;
Amer, Mohamed S;
Wilson, Lesley A;
Migliore, Marco;
Cheung, Sin Y;
Rubaiy, Hussein N;
Blythe, Nicola M;
Musialowski, Katie E;
Ludlow, Melanie J;
Evans, William D;
Green, Ben L;
Yang, Hongjun;
You, Yun;
Li, Jing;
Fishwick, Colin W G;
Muraki, Katsuhiko;
Beech, David J;
Bon, Robin S

Publication type:

journal article

APT070 (mirococept), a membrane-localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model.

Published in:

2016

By:

Xiao, Fang;
Ma, Liang;
Zhao, Min;
Smith, Richard A;
Huang, Guocai;
Jones, Peter M;
Persaud, Shanta;
Pingitore, Attilio;
Dorling, Anthony;
Lechler, Robert;
Lombardi, Giovanna

Publication type:

journal article

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.

Published in:

2016

By:

Mukhopadhyay, Partha;
Baggelaar, Marc;
Erdelyi, Katalin;
Cao, Zongxian;
Cinar, Resat;
Fezza, Filomena;
Ignatowska ‐ Janlowska, Bogna;
Wilkerson, Jenny;
Gils, Noortje;
Hansen, Thomas;
Ruben, Marc;
Soethoudt, Marjolein;
Heitman, Laura;
Kunos, George;
Maccarrone, Mauro;
Lichtman, Aron;
Pacher, Pál;
Van der Stelt, Mario;
Ignatowska-Janlowska, Bogna;
van Gils, Noortje

Publication type:

journal article

Declaration.

Published in:: 2016
Publication type:: Editorial

Meningeal blood flow is controlled by H2 S-NO crosstalk activating a HNO-TRPA1-CGRP signalling pathway.

Published in:

2016

By:

Dux, Mária;
Will, Christine;
Vogler, Birgit;
Filipovic, Milos R;
Messlinger, Karl;
Dux, Mária

Publication type:

journal article