Works matching IS 00071188 AND DT 2012 AND VI 166 AND IP 5

Results: 32

Monoacylglycerol lipase - a target for drug development?

Published in:

2012

By:

Fowler CJ;
Fowler, C J

Publication type:

journal article

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors.

Published in:

2012

By:

Favreau P;
Benoit E;
Hocking HG;
Carlier L;
D' hoedt D;
Leipold E;
Markgraf R;
Schlumberger S;
Córdova MA;
Gaertner H;
Paolini-Bertrand M;
Hartley O;
Tytgat J;
Heinemann SH;
Bertrand D;
Boelens R;
Stöcklin R;
Molgó J;
Favreau, Philippe;
Benoit, Evelyne

Publication type:

journal article

The cholecystokinin CCK2 receptor antagonist, JNJ-26070109, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1684, doi. 10.1111/j.1476-5381.2012.01878.x

By:

Barrett, TD;
Lagaud, G;
Wagaman, P;
Freedman, JM;
Yan, W;
Andries, L;
Rizzolio, MC;
Morton, MF;
Shankley, NP

Publication type:

Article

Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.

Published in:

2012

By:

Okubo K;
Matsumura M;
Kawaishi Y;
Aoki Y;
Matsunami M;
Okawa Y;
Sekiguchi F;
Kawabata A;
Okubo, Kazumasa;
Matsumura, Midori;
Kawaishi, Yudai;
Aoki, Yuka;
Matsunami, Maho;
Okawa, Yasumasa;
Sekiguchi, Fumiko;
Kawabata, Atsufumi

Publication type:

journal article

The cholecystokinin CCK2 receptor antagonist, JNJ-26070109, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.

Published in:

2012

By:

Barrett TD;
Lagaud G;
Wagaman P;
Freedman JM;
Yan W;
Andries L;
Rizzolio MC;
Morton MF;
Shankley NP;
Barrett, T D;
Lagaud, G;
Wagaman, P;
Freedman, J M;
Yan, W;
Andries, L;
Rizzolio, M C;
Morton, M F;
Shankley, N P

Publication type:

journal article

Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival.

Published in:

2012

By:

Lim KG;
Gray AI;
Pyne S;
Pyne NJ;
Lim, Keng Gat;
Gray, Alexander I;
Pyne, Susan;
Pyne, Nigel J

Publication type:

journal article

Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.

Published in:

2012

By:

Fougerat A;
Smirnova NF;
Gayral S;
Malet N;
Hirsch E;
Wymann MP;
Perret B;
Martinez LO;
Douillon M;
Laffargue M;
Fougerat, A;
Smirnova, N F;
Gayral, S;
Malet, N;
Hirsch, E;
Wymann, M P;
Perret, B;
Martinez, L O;
Douillon, M;
Laffargue, M

Publication type:

journal article

BAY 41-2272, a soluble guanylate cyclase agonist, activates human mononuclear phagocytes.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1617, doi. 10.1111/j.1476-5381.2011.01764.x

By:

Soeiro-Pereira, PV;
Falcai, A;
Kubo, CA;
Oliveira-Júnior, EB;
Marques, OC;
Antunes, E;
Condino-Neto, A

Publication type:

Article

The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.

Published in:

2012

By:

Hawcroft G;
Volpato M;
Marston G;
Ingram N;
Perry SL;
Cockbain AJ;
Race AD;
Munarini A;
Belluzzi A;
Loadman PM;
Coletta PL;
Hull MA;
Hawcroft, G;
Volpato, M;
Marston, G;
Ingram, N;
Perry, S L;
Cockbain, A J;
Race, A D;
Munarini, A

Publication type:

journal article

Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine.

Published in:

2012

By:

Klinger F;
Geier P;
Dorostkar MM;
Chandaka GK;
Yousuf A;
Salzer I;
Kubista H;
Boehm S;
Klinger, Felicia;
Geier, Petra;
Dorostkar, Mario M;
Chandaka, Giri K;
Yousuf, Arsalan;
Salzer, Isabella;
Kubista, Helmut;
Boehm, Stefan

Publication type:

journal article

Ecstasy cannot be assumed to be 3,4-methylenedioxyamphetamine (MDMA).

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1521, doi. 10.1111/j.1476-5381.2012.01940.x

By:

Green, AR;
King, MV;
Shortall, SE;
Fone, KCF

Publication type:

Article

Peripheral neural targets in obesity.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1537, doi. 10.1111/j.1476-5381.2012.01951.x

By:

Page, Amanda J;
Symonds, Erin;
Peiris, Madusha;
Blackshaw, L Ashley;
Young, Richard L

Publication type:

Article

Role of mixed ion channel effects in the cardiovascular safety assessment of the novel anti-MRSA fluoroquinolone JNJ-Q2.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1694, doi. 10.1111/j.1476-5381.2012.01874.x

By:

Eichenbaum, G;
Pugsley, MK;
Gallacher, DJ;
Towart, R;
McIntyre, G;
Shukla, U;
Davenport, JM;
Lu, HR;
Rohrbacher, J;
Hillsamer, V

Publication type:

Article

Lost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans.

Published in:

2012

By:

Green AR;
King MV;
Shortall SE;
Fone KC;
Green, A R;
King, M V;
Shortall, S E;
Fone, K C F

Publication type:

journal article

BAY 41-2272, a soluble guanylate cyclase agonist, activates human mononuclear phagocytes.

Published in:

2012

By:

Soeiro-Pereira PV;
Falcai A;
Kubo CA;
Oliveira-Júnior EB;
Marques OC;
Antunes E;
Condino-Neto A;
Soeiro-Pereira, P V;
Falcai, A;
Kubo, C A;
Oliveira-Júnior, E B;
Marques, O C;
Antunes, E;
Condino-Neto, A

Publication type:

journal article

Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1669, doi. 10.1111/j.1476-5381.2012.01849.x

By:

Zhou, Wen-jing;
Zhang, Xu;
Cheng, Chao;
Wang, Fang;
Wang, Xiao-kun;
Liang, Yong-ju;
To, Kenneth Kin Wah;
Zhou, Wang;
Huang, Hong-bing;
Fu, Li-wu

Publication type:

Article

Monoacylglycerol lipase - a target for drug development?

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1568, doi. 10.1111/j.1476-5381.2012.01950.x

By:

Fowler, CJ

Publication type:

Article

Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1605, doi. 10.1111/j.1476-5381.2012.01862.x

By:

Lim, Keng Gat;
Gray, Alexander I;
Pyne, Susan;
Pyne, Nigel J

Publication type:

Article

Erratum.

Published in:: 2012
Publication type:: Erratum

Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1643, doi. 10.1111/j.1476-5381.2012.01866.x

By:

Fougerat, A;
Smirnova, NF;
Gayral, S;
Malet, N;
Hirsch, E;
Wymann, MP;
Perret, B;
Martinez, LO;
Douillon, M;
Laffargue, M

Publication type:

Article

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1654, doi. 10.1111/j.1476-5381.2012.01837.x

By:

Favreau, Philippe;
Benoit, Evelyne;
Hocking, Henry G;
Carlier, Ludovic;
D' hoedt, Dieter;
Leipold, Enrico;
Markgraf, René;
Schlumberger, Sébastien;
Córdova, Marco A;
Gaertner, Hubert;
Paolini-Bertrand, Marianne;
Hartley, Oliver;
Tytgat, Jan;
Heinemann, Stefan H;
Bertrand, Daniel;
Boelens, Rolf;
Stöcklin, Reto;
Molgó, Jordi

Publication type:

Article

Lost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1523, doi. 10.1111/j.1476-5381.2011.01819.x

By:

Green, AR;
King, MV;
Shortall, SE;
Fone, KCF

Publication type:

Article

Natural triterpenes modulate immune-inflammatory markers of experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1708, doi. 10.1111/j.1476-5381.2012.01869.x

By:

Martín, R;
Hernández, M;
Córdova, C;
Nieto, ML

Publication type:

Article

MDMA and 5-HT neurotoxicity: the empirical evidence for its adverse effects in humans - no need for translation.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1518, doi. 10.1111/j.1476-5381.2012.01941.x

By:

Parrott, Andrew C

Publication type:

Article

Categorized or continuous? Strength of an association - and linear regression.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1513, doi. 10.1111/j.1476-5381.2012.01960.x

By:

Drummond, Gordon B;
Vowler, Sarah L

Publication type:

Article

Bad statistical practice in pharmacology (and other basic biomedical disciplines): you probably don't know P.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1559, doi. 10.1111/j.1476-5381.2012.01931.x

By:

Lew, Michael J

Publication type:

Article

Neuroprotective and neurotrophic actions of glucagon-like peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1586, doi. 10.1111/j.1476-5381.2012.01971.x

By:

Salcedo, Isidro;
Tweedie, David;
Li, Yazhou;
Greig, Nigel H

Publication type:

Article

Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1631, doi. 10.1111/j.1476-5381.2011.01821.x

By:

Klinger, Felicia;
Geier, Petra;
Dorostkar, Mario M;
Chandaka, Giri K;
Yousuf, Arsalan;
Salzer, Isabella;
Kubista, Helmut;
Boehm, Stefan

Publication type:

Article

Sphingosine kinase: a key to solving the 'French Paradox'?

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1603, doi. 10.1111/j.1476-5381.2012.01898.x

By:

Hengst, Jeremy A;
Yun, Jong K

Publication type:

Article

The successes and limitations of preclinical studies in predicting the pharmacodynamics and safety of cell-surface-targeted biological agents in patients.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1600, doi. 10.1111/j.1476-5381.2012.01916.x

By:

Polson, Andrew G;
Fuji, Reina N

Publication type:

Article

The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1724, doi. 10.1111/j.1476-5381.2012.01882.x

By:

Hawcroft, G;
Volpato, M;
Marston, G;
Ingram, N;
Perry, SL;
Cockbain, AJ;
Race, AD;
Munarini, A;
Belluzzi, A;
Loadman, PM;
Coletta, PL;
Hull, MA

Publication type:

Article

Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 5, p. 1738, doi. 10.1111/j.1476-5381.2012.01886.x

By:

Okubo, Kazumasa;
Matsumura, Midori;
Kawaishi, Yudai;
Aoki, Yuka;
Matsunami, Maho;
Okawa, Yasumasa;
Sekiguchi, Fumiko;
Kawabata, Atsufumi

Publication type:

Article

Works matching IS 00071188 AND DT 2012 AND VI 166 AND IP 5

Monoacylglycerol lipase - a target for drug development?

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors.

The cholecystokinin CCK<sub>2</sub> receptor antagonist, JNJ-26070109, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.

Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.

The cholecystokinin CCK2 receptor antagonist, JNJ-26070109, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.

Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival.

Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.

BAY 41-2272, a soluble guanylate cyclase agonist, activates human mononuclear phagocytes.

The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.

Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine.

Ecstasy cannot be assumed to be 3,4-methylenedioxyamphetamine (MDMA).

Peripheral neural targets in obesity.

Role of mixed ion channel effects in the cardiovascular safety assessment of the novel anti-MRSA fluoroquinolone JNJ-Q2.

Lost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans.

BAY 41-2272, a soluble guanylate cyclase agonist, activates human mononuclear phagocytes.

Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein.

Monoacylglycerol lipase - a target for drug development?

Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival.

Erratum.

Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of Na<sub>V</sub>1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors.

Lost in translation: preclinical studies on 3,4-methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans.

Natural triterpenes modulate immune-inflammatory markers of experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis.

MDMA and 5-HT neurotoxicity: the empirical evidence for its adverse effects in humans - no need for translation.

Categorized or continuous? Strength of an association - and linear regression.

Bad statistical practice in pharmacology (and other basic biomedical disciplines): you probably don't know P.

Neuroprotective and neurotrophic actions of glucagon-like peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders.

Concomitant facilitation of GABA<sub>A</sub> receptors and K<sub>V</sub>7 channels by the non-opioid analgesic flupirtine.

Sphingosine kinase: a key to solving the 'French Paradox'?

The successes and limitations of preclinical studies in predicting the pharmacodynamics and safety of cell-surface-targeted biological agents in patients.

The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE<sub>2</sub>-dependent cell motility.

Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Ca<sub>v</sub>3.2 and TRPA1 channels in mice.