Works matching IS 00071188 AND DT 2012 AND VI 165 AND IP 8

Results: 49

Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling.

Published in:

2012

By:

Oddi S;
Dainese E;
Sandiford S;
Fezza F;
Lanuti M;
Chiurchiù V;
Totaro A;
Catanzaro G;
Barcaroli D;
De Laurenzi V;
Centonze D;
Mukhopadhyay S;
Selent J;
Howlett AC;
Maccarrone M;
Oddi, Sergio;
Dainese, Enrico;
Sandiford, Simone;
Fezza, Filomena;
Lanuti, Mirko

Publication type:

journal article

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.

Published in:

2012

By:

Horváth B;
Magid L;
Mukhopadhyay P;
Bátkai S;
Rajesh M;
Park O;
Tanchian G;
Gao RY;
Goodfellow CE;
Glass M;
Mechoulam R;
Pacher P;
Horváth, Bėla;
Magid, Lital;
Mukhopadhyay, Partha;
Bátkai, Sándor;
Rajesh, Mohanraj;
Park, Ogyi;
Tanchian, Galin;
Gao, Rachel Y

Publication type:

journal article

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus.

Published in:

2012

By:

Rock EM;
Bolognini D;
Limebeer CL;
Cascio MG;
Anavi-Goffer S;
Fletcher PJ;
Mechoulam R;
Pertwee RG;
Parker LA;
Rock, E M;
Bolognini, D;
Limebeer, C L;
Cascio, M G;
Anavi-Goffer, S;
Fletcher, P J;
Mechoulam, R;
Pertwee, R G;
Parker, L A

Publication type:

journal article

Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors.

Published in:

2012

By:

Bátkai S;
Mukhopadhyay P;
Horváth B;
Rajesh M;
Gao RY;
Mahadevan A;
Amere M;
Battista N;
Lichtman AH;
Gauson LA;
Maccarrone M;
Pertwee RG;
Pacher P;
Bátkai, Sándor;
Mukhopadhyay, Partha;
Horváth, Bėla;
Rajesh, Mohanraj;
Gao, Rachel Y;
Mahadevan, Anu;
Amere, Mukkanti

Publication type:

journal article

Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.

Published in:

2012

By:

Kou XH;
Zhu MF;
Chen D;
Lu Y;
Song HZ;
Ye JL;
Yue LF;
Kou, Xin-Hui;
Zhu, Mei-Feng;
Chen, Dai;
Lu, Yi;
Song, Hui-Zhu;
Ye, Jian-Lin;
Yue, Lin-Feng

Publication type:

journal article

Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.

Published in:

2012

By:

Straiker A;
Wager-Miller J;
Hutchens J;
Mackie K;
Straiker, Alex;
Wager-Miller, Jim;
Hutchens, Jacqueline;
Mackie, Ken

Publication type:

journal article

The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.

Published in:

2012

By:

Straiker A;
Wager-Miller J;
Mackie K;
Straiker, Alex;
Wager-Miller, Jim;
Mackie, Ken

Publication type:

journal article

Slow receptor dissociation is not a key factor in the duration of action of inhaled long-acting β2-adrenoceptor agonists.

Published in:

2012

By:

Sykes DA;
Charlton SJ;
Sykes, David A;
Charlton, Steven J

Publication type:

journal article

Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.

Published in:

2012

By:

Miesel A;
Müller-Fielitz H;
Jöhren O;
Vogt FM;
Raasch W;
Miesel, Anja;
Müller-Fielitz, Helge;
Jöhren, Olaf;
Vogt, Florian M;
Raasch, Walter

Publication type:

journal article

Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.

Published in:

2012

By:

Morgan DJ;
Muller CH;
Murataeva NA;
Davis BJ;
Mackie K;
Morgan, Daniel J;
Muller, Charles H;
Murataeva, Natalia A;
Davis, Brian J;
Mackie, Ken

Publication type:

journal article

AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.

Published in:

2012

By:

Bolognini D;
Cascio MG;
Parolaro D;
Pertwee RG;
Bolognini, Daniele;
Cascio, Maria Grazia;
Parolaro, Daniela;
Pertwee, Roger G

Publication type:

journal article

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.

Published in:

2012

By:

Juknat A;
Pietr M;
Kozela E;
Rimmerman N;
Levy R;
Coppola G;
Geschwind D;
Vogel Z;
Juknat, Ana;
Pietr, Maciej;
Kozela, Ewa;
Rimmerman, Neta;
Levy, Rivka;
Coppola, Giovanni;
Geschwind, Daniel;
Vogel, Zvi

Publication type:

journal article

Slow receptor dissociation is not a key factor in the duration of action of inhaled long-acting β2-adrenoceptor agonists.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2672, doi. 10.1111/j.1476-5381.2011.01639.x

By:

Sykes, David A;
Charlton, Steven J

Publication type:

Article

Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells.

Published in:

2012

By:

Dalton GD;
Howlett AC;
Dalton, George D;
Howlett, Allyn C

Publication type:

journal article

Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2771, doi. 10.1111/j.1476-5381.2011.01756.x

By:

Misner, DL;
Frantz, C;
Guo, L;
Gralinski, MR;
Senese, PB;
Ly, J;
Albassam, M;
Kolaja, KL

Publication type:

Article

Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2692, doi. 10.1111/j.1476-5381.2011.01727.x

By:

Kou, Xin-Hui;
Zhu, Mei-Feng;
Chen, Dai;
Lu, Yi;
Song, Hui-Zhu;
Ye, Jian-Lin;
Yue, Lin-Feng

Publication type:

Article

AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2561, doi. 10.1111/j.1476-5381.2011.01503.x

By:

Bolognini, Daniele;
Cascio, Maria Grazia;
Parolaro, Daniela;
Pertwee, Roger G

Publication type:

Article

Combined effects of THC and caffeine on working memory in rats.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2529, doi. 10.1111/j.1476-5381.2011.01554.x

By:

Panlilio, Leigh V;
Ferré, Sergi;
Yasar, Sevil;
Thorndike, Eric B;
Schindler, Charles W;
Goldberg, Steven R

Publication type:

Article

The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABA(A) receptors.

Published in:

2012

By:

Baur R;
Gertsch J;
Sigel E;
Baur, R;
Gertsch, J;
Sigel, E

Publication type:

journal article

Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2497, doi. 10.1111/j.1476-5381.2011.01455.x

By:

Dalton, George D;
Howlett, Allyn C

Publication type:

Article

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2462, doi. 10.1111/j.1476-5381.2011.01381.x

By:

Horváth, Bėla;
Magid, Lital;
Mukhopadhyay, Partha;
Bátkai, Sándor;
Rajesh, Mohanraj;
Park, Ogyi;
Tanchian, Galin;
Gao, Rachel Y;
Goodfellow, Catherine E;
Glass, Michelle;
Mechoulam, Raphael;
Pacher, Pál

Publication type:

Article

Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2707, doi. 10.1111/j.1476-5381.2011.01722.x

By:

Islam, Robiul;
Lynch, Joseph W

Publication type:

Article

Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2575, doi. 10.1111/j.1476-5381.2011.01506.x

By:

Morgan, Daniel J;
Muller, Charles H;
Murataeva, Natalia A;
Davis, Brian J;
Mackie, Ken

Publication type:

Article

Role of neurosteroids in the anticonvulsant activity of midazolam.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2684, doi. 10.1111/j.1476-5381.2011.01733.x

By:

Dhir, Ashish;
Rogawski, Michael A

Publication type:

Article

Compartmentalization of endocannabinoids into lipid rafts in a microglial cell line devoid of caveolin-1.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2436, doi. 10.1111/j.1476-5381.2011.01380.x

By:

Rimmerman, Neta;
Bradshaw, Heather B;
Kozela, Ewa;
Levy, Rivka;
Juknat, Ana;
Vogel, Zvi

Publication type:

Article

Double blockade of angiotensin II (AT1)-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2721, doi. 10.1111/j.1476-5381.2011.01726.x

By:

Miesel, Anja;
Müller-Fielitz, Helge;
Jöhren, Olaf;
Vogt, Florian M;
Raasch, Walter

Publication type:

Article

Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2450, doi. 10.1111/j.1476-5381.2011.01410.x

By:

Bátkai, Sándor;
Mukhopadhyay, Partha;
Horváth, Bėla;
Rajesh, Mohanraj;
Gao, Rachel Y;
Mahadevan, Anu;
Amere, Mukkanti;
Battista, Natalia;
Lichtman, Aron H;
Gauson, Lisa A;
Maccarrone, Mauro;
Pertwee, Roger G;
Pacher, Pál

Publication type:

Article

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2512, doi. 10.1111/j.1476-5381.2011.01461.x

By:

Juknat, Ana;
Pietr, Maciej;
Kozela, Ewa;
Rimmerman, Neta;
Levy, Rivka;
Coppola, Giovanni;
Geschwind, Daniel;
Vogel, Zvi

Publication type:

Article

Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2660, doi. 10.1111/j.1476-5381.2011.01744.x

By:

Straiker, Alex;
Wager-Miller, Jim;
Hutchens, Jacqueline;
Mackie, Ken

Publication type:

Article

The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2758, doi. 10.1111/j.1476-5381.2011.01755.x

By:

Stone, Virginia M;
Dhayal, Shalinee;
Smith, David M;
Lenaghan, Carol;
Brocklehurst, Katy J;
Morgan, Noel G

Publication type:

Article

Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2425, doi. 10.1111/j.1476-5381.2011.01407.x

By:

Sticht, Martin A;
Long, Jonathan Z;
Rock, Erin M;
Limebeer, Cheryl L;
Mechoulam, Raphael;
Cravatt, Benjamin F;
Parker, Linda A

Publication type:

Article

Cannabinoid research in the 2010s.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2409, doi. 10.1111/j.1476-5381.2012.01930.x

By:

Maccarrone, Mauro;
Alexander, Steve PH

Publication type:

Article

Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2787, doi. 10.1111/j.1476-5381.2011.01732.x

By:

Filppula, AM;
Laitila, J;
Neuvonen, PJ;
Backman, JT

Publication type:

Article

The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2652, doi. 10.1111/j.1476-5381.2011.01743.x

By:

Straiker, Alex;
Wager-Miller, Jim;
Mackie, Ken

Publication type:

Article

Glucagon and a glucagon-GLP-1 dual-agonist increases cardiac performance with different metabolic effects in insulin-resistant hearts.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2736, doi. 10.1111/j.1476-5381.2011.01714.x

By:

Axelsen, LN;
Keung, W;
Pedersen, HD;
Meier, E;
Riber, D;
Kjølbye, AL;
Petersen, JS;
Proctor, SD;
Holstein-Rathlou, N-H;
Lopaschuk, GD

Publication type:

Article

Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2799, doi. 10.1111/j.1476-5381.2011.01754.x

By:

Lan, H;
Lin, HV;
Wang, CF;
Wright, MJ;
Xu, S;
Kang, L;
Juhl, K;
Hedrick, JA;
Kowalski, TJ

Publication type:

Article

Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2598, doi. 10.1111/j.1476-5381.2011.01589.x

By:

Alhamoruni, A;
Wright, KL;
Larvin, M;
O'Sullivan, SE

Publication type:

Article

Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2414, doi. 10.1111/j.1476-5381.2011.01497.x

By:

McHugh, Douglas;
Page, Jeremy;
Dunn, Emily;
Bradshaw, Heather B

Publication type:

Article

Corrigendum.

Published in:: 2012
Publication type:: Erratum

So what do we call GPR18 now?

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2411, doi. 10.1111/j.1476-5381.2011.01731.x

By:

Alexander, SPH

Publication type:

Article

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2620, doi. 10.1111/j.1476-5381.2011.01621.x

By:

Rock, EM;
Bolognini, D;
Limebeer, CL;
Cascio, MG;
Anavi-Goffer, S;
Fletcher, PJ;
Mechoulam, R;
Pertwee, RG;
Parker, LA

Publication type:

Article

S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2749, doi. 10.1111/j.1476-5381.2011.01728.x

By:

Rodriguez-Menchaca, Aldo A;
Solis Jr, Ernesto;
Cameron, Krasnodara;
De Felice, Louis J

Publication type:

Article

The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2611, doi. 10.1111/j.1476-5381.2011.01562.x

By:

Kargl, J;
Balenga, NA;
Platzer, W;
Martini, L;
Whistler, JL;
Waldhoer, M

Publication type:

Article

Effects of palmitoylation of Cys415 in helix 8 of the CB1 cannabinoid receptor on membrane localization and signalling.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2635, doi. 10.1111/j.1476-5381.2011.01658.x

By:

Oddi, Sergio;
Dainese, Enrico;
Sandiford, Simone;
Fezza, Filomena;
Lanuti, Mirko;
Chiurchiù, Valerio;
Totaro, Antonio;
Catanzaro, Giuseppina;
Barcaroli, Daniela;
De Laurenzi, Vincenzo;
Centonze, Diego;
Mukhopadhyay, Somnath;
Selent, Jana;
Howlett, Allyn C;
Maccarrone, Mauro

Publication type:

Article

The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABAA receptors.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2479, doi. 10.1111/j.1476-5381.2011.01405.x

By:

Baur, R;
Gertsch, J;
Sigel, E

Publication type:

Article

Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2584, doi. 10.1111/j.1476-5381.2011.01519.x

By:

Whyte, LS;
Ford, L;
Ridge, SA;
Cameron, GA;
Rogers, MJ;
Ross, RA

Publication type:

Article

The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2485, doi. 10.1111/j.1476-5381.2011.01445.x

By:

Booker, Lamont;
Kinsey, Steven G;
Abdullah, Rehab A;
Blankman, Jacqueline L;
Long, Jonathan Z;
Ezzili, Cyrine;
Boger, Dale L;
Cravatt, Benjamin F;
Lichtman, Aron H

Publication type:

Article

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2539, doi. 10.1111/j.1476-5381.2011.01467.x

By:

Scherma, Maria;
Justinová, Zuzana;
Zanettini, Claudio;
Panlilio, Leigh V;
Mascia, Paola;
Fadda, Paola;
Fratta, Walter;
Makriyannis, Alexandros;
Vadivel, Subramanian K;
Gamaleddin, Islam;
Le Foll, Bernard;
Goldberg, Steven R

Publication type:

Article

The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2549, doi. 10.1111/j.1476-5381.2011.01478.x

By:

Olango, WM;
Roche, M;
Ford, GK;
Harhen, B;
Finn, DP

Publication type:

Article