Works matching IS 00071188 AND DT 2012 AND VI 165 AND IP 8

Results: 49

Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling.
Published in:
2012
By:
- Oddi S;
- Dainese E;
- Sandiford S;
- Fezza F;
- Lanuti M;
- Chiurchiù V;
- Totaro A;
- Catanzaro G;
- Barcaroli D;
- De Laurenzi V;
- Centonze D;
- Mukhopadhyay S;
- Selent J;
- Howlett AC;
- Maccarrone M;
- Oddi, Sergio;
- Dainese, Enrico;
- Sandiford, Simone;
- Fezza, Filomena;
- Lanuti, Mirko
Publication type:
journal article
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.
Published in:
2012
By:
- Horváth B;
- Magid L;
- Mukhopadhyay P;
- Bátkai S;
- Rajesh M;
- Park O;
- Tanchian G;
- Gao RY;
- Goodfellow CE;
- Glass M;
- Mechoulam R;
- Pacher P;
- Horváth, Bėla;
- Magid, Lital;
- Mukhopadhyay, Partha;
- Bátkai, Sándor;
- Rajesh, Mohanraj;
- Park, Ogyi;
- Tanchian, Galin;
- Gao, Rachel Y
Publication type:
journal article
Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus.
Published in:
2012
By:
- Rock EM;
- Bolognini D;
- Limebeer CL;
- Cascio MG;
- Anavi-Goffer S;
- Fletcher PJ;
- Mechoulam R;
- Pertwee RG;
- Parker LA;
- Rock, E M;
- Bolognini, D;
- Limebeer, C L;
- Cascio, M G;
- Anavi-Goffer, S;
- Fletcher, P J;
- Mechoulam, R;
- Pertwee, R G;
- Parker, L A
Publication type:
journal article
Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors.
Published in:
2012
By:
- Bátkai S;
- Mukhopadhyay P;
- Horváth B;
- Rajesh M;
- Gao RY;
- Mahadevan A;
- Amere M;
- Battista N;
- Lichtman AH;
- Gauson LA;
- Maccarrone M;
- Pertwee RG;
- Pacher P;
- Bátkai, Sándor;
- Mukhopadhyay, Partha;
- Horváth, Bėla;
- Rajesh, Mohanraj;
- Gao, Rachel Y;
- Mahadevan, Anu;
- Amere, Mukkanti
Publication type:
journal article
Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.
Published in:
2012
By:
- Kou XH;
- Zhu MF;
- Chen D;
- Lu Y;
- Song HZ;
- Ye JL;
- Yue LF;
- Kou, Xin-Hui;
- Zhu, Mei-Feng;
- Chen, Dai;
- Lu, Yi;
- Song, Hui-Zhu;
- Ye, Jian-Lin;
- Yue, Lin-Feng
Publication type:
journal article
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.
Published in:
2012
By:
- Straiker A;
- Wager-Miller J;
- Hutchens J;
- Mackie K;
- Straiker, Alex;
- Wager-Miller, Jim;
- Hutchens, Jacqueline;
- Mackie, Ken
Publication type:
journal article
The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.
Published in:
2012
By:
- Straiker A;
- Wager-Miller J;
- Mackie K;
- Straiker, Alex;
- Wager-Miller, Jim;
- Mackie, Ken
Publication type:
journal article
Slow receptor dissociation is not a key factor in the duration of action of inhaled long-acting β2-adrenoceptor agonists.
Published in:
2012
By:
- Sykes DA;
- Charlton SJ;
- Sykes, David A;
- Charlton, Steven J
Publication type:
journal article
Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.
Published in:
2012
By:
- Miesel A;
- Müller-Fielitz H;
- Jöhren O;
- Vogt FM;
- Raasch W;
- Miesel, Anja;
- Müller-Fielitz, Helge;
- Jöhren, Olaf;
- Vogt, Florian M;
- Raasch, Walter
Publication type:
journal article
Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.
Published in:
2012
By:
- Morgan DJ;
- Muller CH;
- Murataeva NA;
- Davis BJ;
- Mackie K;
- Morgan, Daniel J;
- Muller, Charles H;
- Murataeva, Natalia A;
- Davis, Brian J;
- Mackie, Ken
Publication type:
journal article
AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.
Published in:
2012
By:
- Bolognini D;
- Cascio MG;
- Parolaro D;
- Pertwee RG;
- Bolognini, Daniele;
- Cascio, Maria Grazia;
- Parolaro, Daniela;
- Pertwee, Roger G
Publication type:
journal article
Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.
Published in:
2012
By:
- Juknat A;
- Pietr M;
- Kozela E;
- Rimmerman N;
- Levy R;
- Coppola G;
- Geschwind D;
- Vogel Z;
- Juknat, Ana;
- Pietr, Maciej;
- Kozela, Ewa;
- Rimmerman, Neta;
- Levy, Rivka;
- Coppola, Giovanni;
- Geschwind, Daniel;
- Vogel, Zvi
Publication type:
journal article
Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells.
Published in:
2012
By:
- Dalton GD;
- Howlett AC;
- Dalton, George D;
- Howlett, Allyn C
Publication type:
journal article
The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABA(A) receptors.
Published in:
2012
By:
- Baur R;
- Gertsch J;
- Sigel E;
- Baur, R;
- Gertsch, J;
- Sigel, E
Publication type:
journal article
Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2771, doi. 10.1111/j.1476-5381.2011.01756.x
By:
- Misner, DL;
- Frantz, C;
- Guo, L;
- Gralinski, MR;
- Senese, PB;
- Ly, J;
- Albassam, M;
- Kolaja, KL
Publication type:
Article
Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2692, doi. 10.1111/j.1476-5381.2011.01727.x
By:
- Kou, Xin-Hui;
- Zhu, Mei-Feng;
- Chen, Dai;
- Lu, Yi;
- Song, Hui-Zhu;
- Ye, Jian-Lin;
- Yue, Lin-Feng
Publication type:
Article
AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2561, doi. 10.1111/j.1476-5381.2011.01503.x
By:
- Bolognini, Daniele;
- Cascio, Maria Grazia;
- Parolaro, Daniela;
- Pertwee, Roger G
Publication type:
Article
Combined effects of THC and caffeine on working memory in rats.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2529, doi. 10.1111/j.1476-5381.2011.01554.x
By:
- Panlilio, Leigh V;
- Ferré, Sergi;
- Yasar, Sevil;
- Thorndike, Eric B;
- Schindler, Charles W;
- Goldberg, Steven R
Publication type:
Article
Slow receptor dissociation is not a key factor in the duration of action of inhaled long-acting β2-adrenoceptor agonists.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2672, doi. 10.1111/j.1476-5381.2011.01639.x
By:
- Sykes, David A;
- Charlton, Steven J
Publication type:
Article
Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2497, doi. 10.1111/j.1476-5381.2011.01455.x
By:
- Dalton, George D;
- Howlett, Allyn C
Publication type:
Article
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2462, doi. 10.1111/j.1476-5381.2011.01381.x
By:
- Horváth, Bėla;
- Magid, Lital;
- Mukhopadhyay, Partha;
- Bátkai, Sándor;
- Rajesh, Mohanraj;
- Park, Ogyi;
- Tanchian, Galin;
- Gao, Rachel Y;
- Goodfellow, Catherine E;
- Glass, Michelle;
- Mechoulam, Raphael;
- Pacher, Pál
Publication type:
Article
Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2707, doi. 10.1111/j.1476-5381.2011.01722.x
By:
- Islam, Robiul;
- Lynch, Joseph W
Publication type:
Article
Role of neurosteroids in the anticonvulsant activity of midazolam.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2684, doi. 10.1111/j.1476-5381.2011.01733.x
By:
- Dhir, Ashish;
- Rogawski, Michael A
Publication type:
Article
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2660, doi. 10.1111/j.1476-5381.2011.01744.x
By:
- Straiker, Alex;
- Wager-Miller, Jim;
- Hutchens, Jacqueline;
- Mackie, Ken
Publication type:
Article
The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2758, doi. 10.1111/j.1476-5381.2011.01755.x
By:
- Stone, Virginia M;
- Dhayal, Shalinee;
- Smith, David M;
- Lenaghan, Carol;
- Brocklehurst, Katy J;
- Morgan, Noel G
Publication type:
Article
Double blockade of angiotensin II (AT1)-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2721, doi. 10.1111/j.1476-5381.2011.01726.x
By:
- Miesel, Anja;
- Müller-Fielitz, Helge;
- Jöhren, Olaf;
- Vogt, Florian M;
- Raasch, Walter
Publication type:
Article
Cannabinoid research in the 2010s.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2409, doi. 10.1111/j.1476-5381.2012.01930.x
By:
- Maccarrone, Mauro;
- Alexander, Steve PH
Publication type:
Article
Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2512, doi. 10.1111/j.1476-5381.2011.01461.x
By:
- Juknat, Ana;
- Pietr, Maciej;
- Kozela, Ewa;
- Rimmerman, Neta;
- Levy, Rivka;
- Coppola, Giovanni;
- Geschwind, Daniel;
- Vogel, Zvi
Publication type:
Article
The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2652, doi. 10.1111/j.1476-5381.2011.01743.x
By:
- Straiker, Alex;
- Wager-Miller, Jim;
- Mackie, Ken
Publication type:
Article
Compartmentalization of endocannabinoids into lipid rafts in a microglial cell line devoid of caveolin-1.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2436, doi. 10.1111/j.1476-5381.2011.01380.x
By:
- Rimmerman, Neta;
- Bradshaw, Heather B;
- Kozela, Ewa;
- Levy, Rivka;
- Juknat, Ana;
- Vogel, Zvi
Publication type:
Article
Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2425, doi. 10.1111/j.1476-5381.2011.01407.x
By:
- Sticht, Martin A;
- Long, Jonathan Z;
- Rock, Erin M;
- Limebeer, Cheryl L;
- Mechoulam, Raphael;
- Cravatt, Benjamin F;
- Parker, Linda A
Publication type:
Article
Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2450, doi. 10.1111/j.1476-5381.2011.01410.x
By:
- Bátkai, Sándor;
- Mukhopadhyay, Partha;
- Horváth, Bėla;
- Rajesh, Mohanraj;
- Gao, Rachel Y;
- Mahadevan, Anu;
- Amere, Mukkanti;
- Battista, Natalia;
- Lichtman, Aron H;
- Gauson, Lisa A;
- Maccarrone, Mauro;
- Pertwee, Roger G;
- Pacher, Pál
Publication type:
Article
Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2787, doi. 10.1111/j.1476-5381.2011.01732.x
By:
- Filppula, AM;
- Laitila, J;
- Neuvonen, PJ;
- Backman, JT
Publication type:
Article
Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2575, doi. 10.1111/j.1476-5381.2011.01506.x
By:
- Morgan, Daniel J;
- Muller, Charles H;
- Murataeva, Natalia A;
- Davis, Brian J;
- Mackie, Ken
Publication type:
Article
Glucagon and a glucagon-GLP-1 dual-agonist increases cardiac performance with different metabolic effects in insulin-resistant hearts.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2736, doi. 10.1111/j.1476-5381.2011.01714.x
By:
- Axelsen, LN;
- Keung, W;
- Pedersen, HD;
- Meier, E;
- Riber, D;
- Kjølbye, AL;
- Petersen, JS;
- Proctor, SD;
- Holstein-Rathlou, N-H;
- Lopaschuk, GD
Publication type:
Article
Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2799, doi. 10.1111/j.1476-5381.2011.01754.x
By:
- Lan, H;
- Lin, HV;
- Wang, CF;
- Wright, MJ;
- Xu, S;
- Kang, L;
- Juhl, K;
- Hedrick, JA;
- Kowalski, TJ
Publication type:
Article
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2598, doi. 10.1111/j.1476-5381.2011.01589.x
By:
- Alhamoruni, A;
- Wright, KL;
- Larvin, M;
- O'Sullivan, SE
Publication type:
Article
Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2414, doi. 10.1111/j.1476-5381.2011.01497.x
By:
- McHugh, Douglas;
- Page, Jeremy;
- Dunn, Emily;
- Bradshaw, Heather B
Publication type:
Article
Corrigendum.
Published in:
2012
Publication type:
Erratum
So what do we call GPR18 now?
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2411, doi. 10.1111/j.1476-5381.2011.01731.x
By:
- Alexander, SPH
Publication type:
Article
Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2620, doi. 10.1111/j.1476-5381.2011.01621.x
By:
- Rock, EM;
- Bolognini, D;
- Limebeer, CL;
- Cascio, MG;
- Anavi-Goffer, S;
- Fletcher, PJ;
- Mechoulam, R;
- Pertwee, RG;
- Parker, LA
Publication type:
Article
S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2749, doi. 10.1111/j.1476-5381.2011.01728.x
By:
- Rodriguez-Menchaca, Aldo A;
- Solis Jr, Ernesto;
- Cameron, Krasnodara;
- De Felice, Louis J
Publication type:
Article
The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2611, doi. 10.1111/j.1476-5381.2011.01562.x
By:
- Kargl, J;
- Balenga, NA;
- Platzer, W;
- Martini, L;
- Whistler, JL;
- Waldhoer, M
Publication type:
Article
Effects of palmitoylation of Cys415 in helix 8 of the CB1 cannabinoid receptor on membrane localization and signalling.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2635, doi. 10.1111/j.1476-5381.2011.01658.x
By:
- Oddi, Sergio;
- Dainese, Enrico;
- Sandiford, Simone;
- Fezza, Filomena;
- Lanuti, Mirko;
- Chiurchiù, Valerio;
- Totaro, Antonio;
- Catanzaro, Giuseppina;
- Barcaroli, Daniela;
- De Laurenzi, Vincenzo;
- Centonze, Diego;
- Mukhopadhyay, Somnath;
- Selent, Jana;
- Howlett, Allyn C;
- Maccarrone, Mauro
Publication type:
Article
The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABAA receptors.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2479, doi. 10.1111/j.1476-5381.2011.01405.x
By:
- Baur, R;
- Gertsch, J;
- Sigel, E
Publication type:
Article
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2584, doi. 10.1111/j.1476-5381.2011.01519.x
By:
- Whyte, LS;
- Ford, L;
- Ridge, SA;
- Cameron, GA;
- Rogers, MJ;
- Ross, RA
Publication type:
Article
The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2485, doi. 10.1111/j.1476-5381.2011.01445.x
By:
- Booker, Lamont;
- Kinsey, Steven G;
- Abdullah, Rehab A;
- Blankman, Jacqueline L;
- Long, Jonathan Z;
- Ezzili, Cyrine;
- Boger, Dale L;
- Cravatt, Benjamin F;
- Lichtman, Aron H
Publication type:
Article
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2539, doi. 10.1111/j.1476-5381.2011.01467.x
By:
- Scherma, Maria;
- Justinová, Zuzana;
- Zanettini, Claudio;
- Panlilio, Leigh V;
- Mascia, Paola;
- Fadda, Paola;
- Fratta, Walter;
- Makriyannis, Alexandros;
- Vadivel, Subramanian K;
- Gamaleddin, Islam;
- Le Foll, Bernard;
- Goldberg, Steven R
Publication type:
Article
The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 8, p. 2549, doi. 10.1111/j.1476-5381.2011.01478.x
By:
- Olango, WM;
- Roche, M;
- Ford, GK;
- Harhen, B;
- Finn, DP
Publication type:
Article