Works matching IS 00071188 AND DT 2012 AND VI 165 AND IP 6

Results: 40

Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1801, doi. 10.1111/j.1476-5381.2011.01645.x

By:

Czikora, Á;
Lizanecz, E;
Bakó, P;
Rutkai, I;
Ruzsnavszky, F;
Magyar, J;
Pórszász, R;
Kark, T;
Facskó, A;
Papp, Z;
Édes, I;
Tóth, A

Publication type:

Article

The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.

Published in:

2012

By:

Laburthe M;
Voisin T;
Laburthe, Marc;
Voisin, Thierry

Publication type:

journal article

A novel fluorescent histamine H(1) receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands.

Published in:

2012

By:

Rose RH;
Briddon SJ;
Hill SJ;
Rose, Rachel H;
Briddon, Stephen J;
Hill, Stephen J

Publication type:

journal article

Potent anti-inflammatory effect of a novel furan-2,5-dione derivative, BPD, mediated by dual suppression of COX-2 activity and LPS-induced inflammatory gene expression via NF-κB inactivation.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1926, doi. 10.1111/j.1476-5381.2011.01670.x

By:

Shin, Ji-Sun;
Park, Seung-Jae;
Ryu, Suran;
Kang, Han Byul;
Kim, Tae Woo;
Choi, Jung-Hye;
Lee, Jae-Yeol;
Cho, Young-Wuk;
Lee, Kyung-Tae

Publication type:

Article

Predicting the emetic liability of novel chemical entities: a comparative study.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1848, doi. 10.1111/j.1476-5381.2011.01669.x

By:

du Sert, Nathalie Percie;
Holmes, Anthony M;
Wallis, Rob;
Andrews, Paul LR

Publication type:

Article

Mandarin Translations.

Published in:: 2012
Publication type:: journal article

Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects.

Published in:

2012

By:

Capasso R;
Aviello G;
Romano B;
Borrelli F;
De Petrocellis L;
Di Marzo V;
Izzo AA;
Capasso, Raffaele;
Aviello, Gabriella;
Romano, Barbara;
Borrelli, Francesca;
De Petrocellis, Luciano;
Di Marzo, Vincenzo;
Izzo, Angelo A

Publication type:

journal article

TNF-α-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways.

Published in:

2012

By:

Makwana R;
Gozzard N;
Spina D;
Page C;
Makwana, R;
Gozzard, N;
Spina, D;
Page, C

Publication type:

journal article

Role of 5-HT(1) receptor subtypes in the modulation of pain and synaptic transmission in rat spinal superficial dorsal horn.

Published in:

2012

By:

Jeong HJ;
Mitchell VA;
Vaughan CW;
Jeong, Hyo-Jin;
Mitchell, Vanessa A;
Vaughan, Christopher W

Publication type:

journal article

Different in vitro and in vivo profiles of substituted 3-aminopropylphosphinate and 3-aminopropyl(methyl)phosphinate GABA(B) receptor agonists as inhibitors of transient lower oesophageal sphincter relaxation.

Published in:

2012

By:

Lehmann A;
Antonsson M;
Aurell-Holmberg A;
Blackshaw LA;
Brändén L;
Elebring T;
Jensen J;
Kärrberg L;
Mattsson JP;
Nilsson K;
Oja SS;
Saransaari P;
von Unge S;
Lehmann, A;
Antonsson, M;
Aurell-Holmberg, A;
Blackshaw, L A;
Brändén, L;
Elebring, T;
Jensen, J

Publication type:

journal article

Potent anti-inflammatory effect of a novel furan-2,5-dione derivative, BPD, mediated by dual suppression of COX-2 activity and LPS-induced inflammatory gene expression via NF-κB inactivation.

Published in:

2012

By:

Shin JS;
Park SJ;
Ryu S;
Kang HB;
Kim TW;
Choi JH;
Lee JY;
Cho YW;
Lee KT;
Shin, Ji-Sun;
Park, Seung-Jae;
Ryu, Suran;
Kang, Han Byul;
Kim, Tae Woo;
Choi, Jung-Hye;
Lee, Jae-Yeol;
Cho, Young-Wuk;
Lee, Kyung-Tae

Publication type:

journal article

Roflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide.

Published in:

2012

By:

Buenestado A;
Grassin-Delyle S;
Guitard F;
Naline E;
Faisy C;
Israël-Biet D;
Sage E;
Bellamy JF;
Tenor H;
Devillier P;
Buenestado, A;
Grassin-Delyle, S;
Guitard, F;
Naline, E;
Faisy, C;
Israël-Biet, D;
Sage, E;
Bellamy, J F;
Tenor, H;
Devillier, P

Publication type:

journal article

Role of 5-HT1 receptor subtypes in the modulation of pain and synaptic transmission in rat spinal superficial dorsal horn.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1956, doi. 10.1111/j.1476-5381.2011.01685.x

By:

Jeong, Hyo-Jin;
Mitchell, Vanessa A;
Vaughan, Christopher W

Publication type:

Article

A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1789, doi. 10.1111/j.1476-5381.2011.01640.x

By:

Rose, Rachel H;
Briddon, Stephen J;
Hill, Stephen J

Publication type:

Article

Hydrogen sulphide-releasing diclofenac derivatives inhibit breast cancer-induced osteoclastogenesis in vitro and prevent osteolysis ex vivo.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1914, doi. 10.1111/j.1476-5381.2011.01704.x

By:

Frantzias, J;
Logan, JG;
Mollat, P;
Sparatore, A;
Del Soldato, P;
Ralston, SH;
Idris, AI

Publication type:

Article

d-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1941, doi. 10.1111/j.1476-5381.2011.01680.x

By:

Lu, Jin-Miao;
Gong, Nian;
Wang, Yan-Chao;
Wang, Yong-Xiang

Publication type:

Article

Lifting the lid on GPCRs: the role of extracellular loops.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1688, doi. 10.1111/j.1476-5381.2011.01629.x

By:

Wheatley, M;
Wootten, D;
Conner, MT;
Simms, J;
Kendrick, R;
Logan, RT;
Poyner, DR;
Barwell, J

Publication type:

Article

Constitutive formation of an RXFP1-signalosome: a novel paradigm in GPCR function and regulation.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1644, doi. 10.1111/j.1476-5381.2011.01470.x

By:

Halls, Michelle L

Publication type:

Article

Role of endothelin-1 in the hyper-responsiveness to nitrovasodilators following acute NOS inhibition.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1992, doi. 10.1111/j.1476-5381.2011.01696.x

By:

Bourque, Stephane L;
Whittingham, Heather A;
Brien, Susan E;
Davidge, Sandra T;
Adams, Michael A

Publication type:

Article

Roflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1877, doi. 10.1111/j.1476-5381.2011.01667.x

By:

Buenestado, A;
Grassin-Delyle, S;
Guitard, F;
Naline, E;
Faisy, C;
Israël-Biet, D;
Sage, E;
Bellamy, JF;
Tenor, H;
Devillier, P

Publication type:

Article

Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1904, doi. 10.1111/j.1476-5381.2011.01689.x

By:

Bodenmann, S;
Hohoff, C;
Freitag, C;
Deckert, J;
Rétey, J V;
Bachmann, V;
Landolt, H-P

Publication type:

Article

Behind the curtain: cellular mechanisms for allosteric modulation of calcium-sensing receptors.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1670, doi. 10.1111/j.1476-5381.2011.01403.x

By:

Cavanaugh, Alice;
Huang, Ying;
Breitwieser, Gerda E

Publication type:

Article

Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables ( Brassicaceae): evidence for TRPA1-independent effects.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1966, doi. 10.1111/j.1476-5381.2011.01703.x

By:

Capasso, Raffaele;
Aviello, Gabriella;
Romano, Barbara;
Borrelli, Francesca;
De Petrocellis, Luciano;
Di Marzo, Vincenzo;
Izzo, Angelo A

Publication type:

Article

Biased signalling and allosteric machines: new vistas and challenges for drug discovery.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1659, doi. 10.1111/j.1476-5381.2011.01749.x

By:

Kenakin, Terry P

Publication type:

Article

TNF-α-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1978, doi. 10.1111/j.1476-5381.2011.01675.x

By:

Makwana, R;
Gozzard, N;
Spina, D;
Page, C

Publication type:

Article

Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathway.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1813, doi. 10.1111/j.1476-5381.2011.01684.x

By:

Gao, Ning;
Cheng, Senping;
Budhraja, Amit;
Gao, Ziyi;
Chen, Jieping;
Liu, E-Hu;
Huang, Cheng;
Chen, Deying;
Yang, Zailin;
Liu, Qun;
Li, Ping;
Shi, Xianglin;
Zhang, Zhuo

Publication type:

Article

Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1717, doi. 10.1111/j.1476-5381.2011.01552.x

By:

Magalhaes, Ana C;
Dunn, Henry;
Ferguson, Stephen SG

Publication type:

Article

A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1891, doi. 10.1111/j.1476-5381.2011.01677.x

By:

Palmer, GM;
Tiran, Z;
Zhou, Z;
Capozzi, ME;
Park, W;
Coletta, C;
Pyriochou, A;
Kliger, Y;
Levy, O;
Borukhov, I;
Dewhirst, MW;
Rotman, G;
Penn, JS;
Papapetropoulos, A

Publication type:

Article

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1704, doi. 10.1111/j.1476-5381.2011.01482.x

By:

Dang, Vu C;
Christie, MacDonald J

Publication type:

Article

Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1836, doi. 10.1111/j.1476-5381.2011.01672.x

By:

Fahrmayr, C;
König, J;
Auge, D;
Mieth, M;
Fromm, MF

Publication type:

Article

Pharmacological modulation of chemokine receptor function.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1617, doi. 10.1111/j.1476-5381.2011.01551.x

By:

Scholten, DJ;
Canals, M;
Maussang, D;
Roumen, L;
Smit, MJ;
Wijtmans, M;
de Graaf, C;
Vischer, HF;
Leurs, R

Publication type:

Article

GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1613, doi. 10.1111/j.1476-5381.2011.01434.x

By:

Insel, PA;
Snead, A;
Murray, F;
Zhang, L;
Yokouchi, H;
Katakia, T;
Kwon, O;
Dimucci, D;
Wilderman, A

Publication type:

Article

Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolaemia-induced atherosclerosis.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 2000, doi. 10.1111/j.1476-5381.2011.01712.x

By:

Lu, Hong;
Balakrishnan, Anju;
Howatt, Deborah A;
Wu, Congqing;
Charnigo, Richard;
Liau, Gene;
Cassis, Lisa A;
Daugherty, Alan

Publication type:

Article

Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1737, doi. 10.1111/j.1476-5381.2011.01620.x

By:

Kelly, MM;
King, EM;
Rider, CF;
Gwozd, C;
Holden, NS;
Eddleston, J;
Zuraw, B;
Leigh, R;
O'Byrne, PM;
Newton, R

Publication type:

Article

The orexin receptor OX1R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1678, doi. 10.1111/j.1476-5381.2011.01510.x

By:

Laburthe, Marc;
Voisin, Thierry

Publication type:

Article

Inhibitory effect of bufalin and cinobufagin on steroidogenesis via the activation of ERK in human adrenocortical cells.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1868, doi. 10.1111/j.1476-5381.2011.01671.x

By:

Kau, Mei-Mei;
Wang, Jiing-Rong;
Tsai, Shiow-Chwen;
Yu, Ching-Han;
Wang, Paulus S

Publication type:

Article

Different in vitro and in vivo profiles of substituted 3-aminopropylphosphinate and 3-aminopropyl(methyl)phosphinate GABAB receptor agonists as inhibitors of transient lower oesophageal sphincter relaxation.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1757, doi. 10.1111/j.1476-5381.2011.01682.x

By:

Lehmann, A;
Antonsson, M;
Aurell-Holmberg, A;
Blackshaw, LA;
Brändén, L;
Elebring, T;
Jensen, J;
Kärrberg, L;
Mattsson, JP;
Nilsson, K;
Oja, SS;
Saransaari, P;
von Unge, S

Publication type:

Article

Ketamine-induced ventricular structural, sympathetic and electrophysiological remodelling: pathological consequences and protective effects of metoprolol.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1748, doi. 10.1111/j.1476-5381.2011.01635.x

By:

Li, Y;
Shi, J;
Yang, BF;
Liu, L;
Han, CL;
Li, WM;
Dong, DL;
Pan, ZW;
Liu, GZ;
Geng, JQ;
Sheng, L;
Tan, XY;
Sun, DH;
Gong, ZH;
Gong, YT

Publication type:

Article

Antiplatelet and antithrombotic effect of F 16618, a new thrombin proteinase-activated receptor-1 (PAR1) antagonist.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1827, doi. 10.1111/j.1476-5381.2011.01668.x

By:

Dumas, M;
Nadal-Wollbold, F;
Gaussem, P;
Perez, M;
Mirault, T;
Létienne, R;
Bourbon, T;
Grelac, F;
Le Grand, B;
Bachelot-Loza, C

Publication type:

Article

Themed section: molecular pharmacology of GPCRs.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 6, p. 1609, doi. 10.1111/j.1476-5381.2011.01679.x

By:

Summers, RJ

Publication type:

Article