Works matching IS 00070920 AND DT 2020 AND VI 123 AND IP 10

Results: 16
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    Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer.

    Published in:
    2020
    By:
    • Greene, Michelle K.;
    • Chen, Ting;
    • Robinson, Eifion;
    • Straubinger, Ninfa L.;
    • Minx, Charlene;
    • Chan, Darren K. W.;
    • Wang, Jun;
    • Burrows, James F.;
    • Van Schaeybroeck, Sandra;
    • Baker, James R.;
    • Caddick, Stephen;
    • Longley, Daniel B.;
    • Mager, Donald E.;
    • Straubinger, Robert M.;
    • Chudasama, Vijay;
    • Scott, Christopher J.
    Publication type:
    journal article
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    Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08.

    Published in:
    2020
    By:
    • Masuishi, Toshiki;
    • Tsuji, Akihito;
    • Kotaka, Masahito;
    • Nakamura, Masato;
    • Kochi, Mitsugu;
    • Takagane, Akinori;
    • Shimada, Ken;
    • Denda, Tadamichi;
    • Segawa, Yoshihiko;
    • Tanioka, Hiroaki;
    • Hara, Hiroki;
    • Sagawa, Tamotsu;
    • Watanabe, Takanori;
    • Takahashi, Takao;
    • Negoro, Yuji;
    • Manaka, Dai;
    • Fujita, Hideto;
    • Suto, Takeshi;
    • Takeuchi, Masahiro;
    • Ichikawa, Wataru
    Publication type:
    journal article
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    A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamics of AsiDNA, a first-in-class DNA repair inhibitor, administered intravenously in patients with advanced solid tumours.

    Published in:
    2020
    By:
    • Le Tourneau, Christophe;
    • Delord, Jean-Pierre;
    • Kotecki, Nuria;
    • Borcoman, Edith;
    • Gomez-Roca, Carlos;
    • Hescot, Ségolène;
    • Jungels, Christiane;
    • Vincent-Salomon, Anne;
    • Cockenpot, Vincent;
    • Eberst, Lauriane;
    • Molé, Audrey;
    • Jdey, Wael;
    • Bono, Françoise;
    • Trochon-Joseph, Véronique;
    • Toussaint, Hélène;
    • Zandanel, Christelle;
    • Adamiec, Olga;
    • de Beaumont, Olivier;
    • Cassier, Philippe Alexandre
    Publication type:
    journal article
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