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Repositioning canakinumab for non-small cell lung cancer-important lessons for drug repurposing in oncology.
Published in:
2022
By:
- Lythgoe, Mark P;
- Prasad, Vinay
Publication type:
journal article
Association between physical activity and neoadjuvant chemotherapy completion and pathologic complete response in primary breast cancer: the CANTO study.
Published in:
2022
By:
- Baker, Jennifer L;
- Di Meglio, Antonio;
- Gbenou, Arnauld S;
- El Mouhebb, Mayssam;
- Iyengar, Neil M;
- Michiels, Stefan;
- Cottu, Paul;
- Lerebours, Florence;
- Coutant, Charles;
- Lesur, Anne;
- Tredan, Oliver;
- Vanlemmens, Laurence;
- Jouannaud, Christelle;
- Hrab, Iona;
- Everhard, Sibille;
- Martin, Anne-Laure;
- Arveux, Patrick;
- Fabrice, Andre;
- Vaz-Luis, Ines;
- Jones, Lee W
Publication type:
journal article
Selective cell cycle arrest in glioblastoma cell lines by quantum molecular resonance alone or in combination with temozolomide.
Published in:
2022
By:
- Catanzaro, Daniela;
- Milani, Gloria;
- Bozza, Angela;
- Bernardi, Martina;
- Chieregato, Katia;
- Menarin, Martina;
- Merlo, Anna;
- Celli, Paola;
- Belli, Romina;
- Peroni, Daniele;
- Pozzato, Alessandro;
- Pozzato, Gianantonio;
- Raneri, Fabio Angelo;
- Volpin, Lorenzo;
- Ruggeri, Marco;
- Astori, Giuseppe
Publication type:
journal article
Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3.
Published in:
2022
By:
- Fischer, Laura E;
- Stintzing, Sebastian;
- von Weikersthal, Ludwig Fischer;
- Modest, Dominik P;
- Decker, Thomas;
- Kiani, Alexander;
- Kaiser, Florian;
- Al-Batran, Salah-Eddin;
- Heintges, Tobias;
- Lerchenmüller, Christian;
- Kahl, Christoph;
- Seipelt, Gernot;
- Kullmann, Frank;
- Stauch, Martina;
- Scheithauer, Werner;
- Giessen-Jung, Clemens;
- Uhlig, Jens;
- Peuser, Bettina;
- Denzlinger, Claudio;
- Stahler, Arndt
Publication type:
journal article
Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions.
Published in:
2022
By:
- Venn, Nicola C;
- Huang, Libby;
- Hovorková, Lenka;
- Muskovic, Walter;
- Wong, Marie;
- Law, Tamara;
- Heatley, Susan L;
- Khaw, Seong Lin;
- Revesz, Tom;
- Dalla Pozza, Luciano;
- Shaw, Peter J;
- Fraser, Chris;
- Moore, Andrew S;
- Cross, Siobhan;
- Bendak, Katerina;
- Norris, Murray D;
- Henderson, Michelle J;
- White, Deborah L;
- Cowley, Mark J;
- Trahair, Toby N
Publication type:
journal article
Benefit from upfront FOLFOXIRI and bevacizumab in BRAFV600E-mutated metastatic colorectal cancer patients: does primary tumour location matter?
Published in:
2022
By:
- Moretto, Roberto;
- Elliott, Andrew;
- Rossini, Daniele;
- Intini, Rossana;
- Conca, Veronica;
- Pietrantonio, Filippo;
- Sartore-Bianchi, Andrea;
- Antoniotti, Carlotta;
- Rasola, Cosimo;
- Scartozzi, Mario;
- Salati, Massimiliano;
- Pella, Nicoletta;
- Calegari, Maria Alessandra;
- Carullo, Martina;
- Corti, Francesca;
- Mauri, Gianluca;
- Fassan, Matteo;
- Masi, Gianluca;
- Brodskiy, Pavel;
- Lenz, Heinz-Josef
Publication type:
journal article
Vitamin D supplementation and total cancer incidence and mortality by daily vs. infrequent large-bolus dosing strategies: a meta-analysis of randomised controlled trials.
Published in:
2022
By:
- Keum, N;
- Chen, Q-Y;
- Lee, D H;
- Manson, J E;
- Giovannucci, E
Publication type:
journal article
Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment.
Published in:
2022
By:
- Kim, Sheehyun;
- Lim, Yoojoo;
- Kang, Jun-Kyu;
- Kim, Hwang-Phill;
- Roh, Hanseong;
- Kim, Su Yeon;
- Lee, Dongin;
- Bang, Duhee;
- Jeong, Seung-Yong;
- Park, Kyu Joo;
- Han, Sae-Won;
- Kim, Tae-You
Publication type:
journal article
Use of anti-androgenic 5α-reductase inhibitors and risk of oesophageal and gastric cancer by histological type and anatomical sub-site.
Published in:
2022
By:
- Rabbani, Sirus;
- Santoni, Giola;
- Lagergren, Jesper;
- Xie, Shao-Hua
Publication type:
journal article
Impact of germline mutations in cancer-predisposing genes on long-term survival in patients with epithelial ovarian cancer.
Published in:
2022
By:
- Kotsopoulos, Joanne;
- Zamani, Neda;
- Rosen, Barry;
- McLaughlin, John R;
- Risch, Harvey A;
- Kim, Shana J;
- Sun, Ping;
- Akbari, Mohammad Reza;
- Narod, Steven A
Publication type:
journal article
Immune checkpoint inhibitors alone vs immune checkpoint inhibitors-combined chemotherapy for NSCLC patients with high PD-L1 expression: a network meta-analysis.
Published in:
2022
By:
- Wang, Yimin;
- Han, Hedong;
- Zhang, Fang;
- Lv, Tangfeng;
- Zhan, Ping;
- Ye, Mingxiang;
- Song, Yong;
- Liu, Hongbing
Publication type:
journal article
Ethnic inequalities in routes to diagnosis of cancer: a population-based UK cohort study.
Published in:
2022
By:
- Martins, Tanimola;
- Abel, Gary;
- Ukoumunne, Obioha C;
- Mounce, Luke T A;
- Price, Sarah;
- Lyratzopoulos, Georgios;
- Chinegwundoh, Frank;
- Hamilton, William
Publication type:
journal article
Inhibition of PFKFB3 in HER2-positive gastric cancer improves sensitivity to trastuzumab by inducing tumour vessel normalisation.
Published in:
2022
By:
- Yao, Xingxing;
- He, Zhanke;
- Qin, Caolitao;
- Zhang, Penghao;
- Sui, Chuyang;
- Deng, Xiangqian;
- Fang, Yuxin;
- Li, Guoxin;
- Shi, Jiaolong
Publication type:
journal article
The mediating role of combined lifestyle factors on the relationship between education and gastric cancer in the Stomach cancer Pooling (StoP) Project.
Published in:
2022
By:
- Alicandro, Gianfranco;
- Bertuccio, Paola;
- Collatuzzo, Giulia;
- Pelucchi, Claudio;
- Bonzi, Rossella;
- Liao, Linda M;
- Rabkin, Charles S;
- Sinha, Rashmi;
- Negri, Eva;
- Dalmartello, Michela;
- Zaridze, David;
- Maximovich, Dmitry;
- Vioque, Jesus;
- Garcia de la Hera, Manoli;
- Tsugane, Shoichiro;
- Hidaka, Akihisa;
- Hamada, Gerson Shigueaki;
- López-Carrillo, Lizbeth;
- Hernández-Ramírez, Raúl Ulises;
- Malekzadeh, Reza
Publication type:
journal article
Overall survival of patients with metastatic breast cancer in Sweden: a nationwide study.
Published in:
2022
By:
- Valachis, Antonis;
- Carlqvist, Peter;
- Ma, Yuanjun;
- Szilcz, Máté;
- Freilich, Jonatan;
- Vertuani, Simona;
- Holm, Barbro;
- Lindman, Henrik
Publication type:
journal article
The STING pathway: Therapeutic vulnerabilities in ovarian cancer.
Published in:
2022
By:
- Shakfa, Noor;
- Li, Deyang;
- Nersesian, Sarah;
- Wilson-Sanchez, Juliette;
- Koti, Madhuri
Publication type:
journal article
Simultaneous targeting of glycolysis and oxidative phosphorylation as a therapeutic strategy to treat diffuse large B-cell lymphoma.
Published in:
2022
By:
- Noble, Richard A;
- Thomas, Huw;
- Zhao, Yan;
- Herendi, Lili;
- Howarth, Rachel;
- Dragoni, Ilaria;
- Keun, Hector C;
- Vellano, Christopher P;
- Marszalek, Joseph R;
- Wedge, Stephen R
Publication type:
journal article
Upregulation of CXCL1 and LY9 contributes to BRCAness in ovarian cancer and mediates response to PARPi and immune checkpoint blockade.
Published in:
2022
By:
- Chen, Tingting;
- Yu, Tong;
- Zhuang, Shuping;
- Geng, Yiding;
- Xue, Junwen;
- Wang, Jiayi;
- Ai, Liqiang;
- Chen, Bo;
- Zhao, Zhangxiang;
- Li, Yawei;
- Wang, Jinghao;
- Liang, Haihai;
- Xu, Yan;
- Gu, Yunyan
Publication type:
journal article
POH1/Rpn11/PSMD14: a journey from basic research in fission yeast to a prognostic marker and a druggable target in cancer cells.
Published in:
2022
By:
- Spataro, Vito;
- Buetti-Dinh, Antoine
Publication type:
journal article
Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer.
Published in:
2022
By:
- Michmerhuizen, Anna R;
- Lerner, Lynn M;
- Ward, Connor;
- Pesch, Andrea M;
- Zhang, Amanda;
- Schwartz, Rachel;
- Wilder-Romans, Kari;
- Eisner, Joel R;
- Rae, James M;
- Pierce, Lori J;
- Speers, Corey W
Publication type:
journal article
Targeting epidermal growth factor receptor in paclitaxel-resistant human breast and lung cancer cells with upregulated glucose-6-phosphate dehydrogenase.
Published in:
2022
By:
- Min, Hye-Young;
- Lee, Ho Jin;
- Suh, Young-Ah;
- Pei, Honglan;
- Kwon, Hyukjin;
- Jang, Hyun-Ji;
- Yun, Hye Jeong;
- Moon, Hyeong-Gon;
- Lee, Ho-Young
Publication type:
journal article
Diagnostic routes and time intervals for ovarian cancer in nine international jurisdictions; findings from the International Cancer Benchmarking Partnership (ICBP).
Published in:
2022
By:
- Menon, Usha;
- Weller, David;
- Falborg, Alina Zalounina;
- Jensen, Henry;
- Butler, John;
- Barisic, Andriana;
- Knudsen, Anne Kari;
- Bergin, Rebecca J;
- Brewster, David H;
- Cairnduff, Victoria;
- Fourkala, Evangelia Ourania;
- Gavin, Anna T;
- Grunfeld, Eva;
- Harland, Elizabeth;
- Kalsi, Jatinderpal;
- Law, Rebecca-Jane;
- Lin, Yulan;
- Turner, Donna;
- Neal, Richard D;
- White, Victoria
Publication type:
journal article
Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade.
Published in:
2022
By:
- Eslami-S, Zahra;
- Cortés-Hernández, Luis Enrique;
- Thomas, Frédéric;
- Pantel, Klaus;
- Alix-Panabières, Catherine
Publication type:
journal article
Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells.
Published in:
2022
By:
- Zhou, Guoying;
- Lieshout, Ruby;
- van Tienderen, Gilles S.;
- de Ruiter, Valeska;
- van Royen, Martin E.;
- Boor, Patrick P. C.;
- Magré, Luc;
- Desai, Jyaysi;
- Köten, Kübra;
- Kan, Yik Yang;
- Ge, Zhouhong;
- Campos Carrascosa, Lucia;
- Geuijen, Cecile;
- Sprengers, Dave;
- van der Laan, Luc J. W.;
- Verstegen, Monique M. A.;
- Kwekkeboom, Jaap
Publication type:
journal article
STAT1 is regulated by TRIM24 and promotes immunosuppression in head and neck squamous carcinoma cells, but enhances T cell antitumour immunity in the tumour microenvironment.
Published in:
2022
By:
- Anderson, Kelvin;
- Ryan, Nathan;
- Nedungadi, Divya;
- Lamenza, Felipe;
- Swingler, Michael;
- Siddiqui, Arham;
- Satoskar, Abhay;
- Upadhaya, Puja;
- Pietrzak, Maciej;
- Oghumu, Steve
Publication type:
journal article
Steering decision making by terminology: oligometastatic versus argometastatic.
Published in:
2022
By:
- Szturz, Petr;
- Vermorken, Jan B.
Publication type:
journal article
Resectability, conversion, metastasectomy and outcome according to RAS and BRAF status for metastatic colorectal cancer in the prospective RAXO study.
Published in:
2022
By:
- Uutela, Aki;
- Osterlund, Emerik;
- Halonen, Päivi;
- Kallio, Raija;
- Ålgars, Annika;
- Salminen, Tapio;
- Lamminmäki, Annamarja;
- Soveri, Leena-Maija;
- Ristamäki, Raija;
- Lehtomäki, Kaisa;
- Stedt, Hanna;
- Heervä, Eetu;
- Muhonen, Timo;
- Kononen, Juha;
- Nordin, Arno;
- Ovissi, Ali;
- Kytölä, Soili;
- Keinänen, Mauri;
- Sundström, Jari;
- Nieminen, Lasse
Publication type:
journal article
Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium.
Published in:
2022
By:
- Martimianaki, Georgia;
- Alicandro, Gianfranco;
- Pelucchi, Claudio;
- Bonzi, Rossella;
- Rota, Matteo;
- Hu, Jinfu;
- Johnson, Kenneth C.;
- Rabkin, Charles S.;
- Liao, Linda M.;
- Sinha, Rashmi;
- Zhang, Zuo-Feng;
- Dalmartello, Michela;
- Lunet, Nuno;
- Morais, Samantha;
- Palli, Domenico;
- Ferraroni, Monica;
- Yu, Guo-Pei;
- Tsugane, Shoichiro;
- Hidaka, Akihisa;
- Curado, Maria Paula
Publication type:
journal article
Personalised selection of experimental treatment in patients with advanced solid cancer is feasible using whole-genome sequencing.
Published in:
2022
By:
- Pruis, Melinda A.;
- Groenendijk, Floris H.;
- Badloe, K. Sangeeta;
- van Puffelen, Andrea;
- Robbrecht, Debbie;
- Dinjens, Winand N. M.;
- Sleijfer, Stefan;
- Dingemans, Anne-Marie C.;
- von der Thüsen, Jan H.;
- Roepman, Paul;
- Lolkema, Martijn P.
Publication type:
journal article
Dose-dense sequential adjuvant chemotherapy in the trastuzumab era: final long-term results of the Hellenic Cooperative Oncology Group Phase III HE10/05 Trial.
Published in:
2022
By:
- Zagouri, Flora;
- Koliou, Georgia-Angeliki;
- Dimitrakopoulos, Foteinos;
- Papadimitriou, Christos;
- Binas, Ioannis;
- Koutras, Angelos;
- Papakostas, Pavlos;
- Markopoulos, Christos;
- Venizelos, Vasileios;
- Xepapadakis, Grigorios;
- Andrikopoulou, Αngeliki;
- Karanikiotis, Charisios;
- Psyrri, Amanda;
- Bafaloukos, Dimitrios;
- Kosmidis, Paris;
- Aravantinos, Gerasimos;
- Res, Eleni;
- Mauri, Davide;
- Koumarianou, Anna;
- Petraki, Kalliopi
Publication type:
journal article
Regulatory T cells induce a suppressive immune milieu and promote lymph node metastasis in intrahepatic cholangiocarcinoma.
Published in:
2022
By:
- Konishi, Daisuke;
- Umeda, Yuzo;
- Yoshida, Kazuhiro;
- Shigeyasu, Kunitoshi;
- Yano, Shuya;
- Toji, Tomohiro;
- Takeda, Sho;
- Yoshida, Ryuichi;
- Yasui, Kazuya;
- Fuji, Tomokazu;
- Matsumoto, Kazuyuki;
- Kishimoto, Hiroyuki;
- Michiue, Hiroyuki;
- Teraishi, Fuminori;
- Kato, Hironari;
- Tazawa, Hiroshi;
- Yanai, Hiroyuki;
- Yagi, Takahito;
- Goel, Ajay;
- Fujiwara, Toshiyoshi
Publication type:
journal article
Anti-epileptic drugs and prostate cancer-specific mortality compared to non-users of anti-epileptic drugs in the Finnish Randomized Study of Screening for Prostate Cancer.
Published in:
2022
By:
- Salminen, Jukka K.;
- Mehtola, Aino;
- Talala, Kirsi;
- Taari, Kimmo;
- Mäkinen, Jussi;
- Peltola, Jukka;
- Tammela, Teuvo L. J.;
- Auvinen, Anssi;
- Murtola, Teemu J.
Publication type:
journal article
Gene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy.
Published in:
2022
By:
- Emons, Georg;
- Auslander, Noam;
- Jo, Peter;
- Kitz, Julia;
- Azizian, Azadeh;
- Hu, Yue;
- Hess, Clemens F.;
- Roedel, Claus;
- Sax, Ulrich;
- Salinas, Gabriela;
- Stroebel, Philipp;
- Kramer, Frank;
- Beissbarth, Tim;
- Grade, Marian;
- Ghadimi, Michael;
- Ruppin, Eytan;
- Ried, Thomas;
- Gaedcke, Jochen
Publication type:
journal article
TXN inhibitor impedes radioresistance of colorectal cancer cells with decreased ALDH1L2 expression via TXN/NF-κB signaling pathway.
Published in:
2022
By:
- Yu, Lu;
- Guo, Qiqing;
- Luo, Ziqian;
- Wang, Yongjia;
- Weng, Jiawen;
- Chen, Yuchuan;
- Liang, Weijie;
- Li, Yiyi;
- Zhang, Yuqin;
- Chen, Keli;
- Chen, Zhenhui;
- Ding, Yi;
- Zhang, Yaowei
Publication type:
journal article
Intensity of care in cancer patients in the last year of life: a retrospective data linkage study.
Published in:
2022
By:
- Luta, Xhyljeta;
- Diernberger, Katharina;
- Bowden, Joanna;
- Droney, Joanne;
- Hall, Peter;
- Marti, Joachim
Publication type:
journal article
Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Published in:
2022
By:
- Schmid, Felicitas;
- Dahlmann, Mathias;
- Röhrich, Hanna;
- Kobelt, Dennis;
- Hoffmann, Jens;
- Burock, Susen;
- Walther, Wolfgang;
- Stein, Ulrike
Publication type:
journal article
MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2.
Published in:
2022
By:
- Yan, Weiwei;
- Han, Qiuying;
- Gong, Lin;
- Zhan, Xiaoyan;
- Li, Wanjin;
- Guo, Zenglin;
- Zhao, Jiangman;
- Li, Tingting;
- Bai, Zhaofang;
- Wu, Jin;
- Huang, Yan;
- Lv, Luye;
- Zhao, Haixin;
- Cai, Hong;
- Huang, Shaoyi;
- Diao, Xinwei;
- Chen, Yuan;
- Gong, Weili;
- Xia, Qing;
- Man, Jianghong
Publication type:
journal article
Integrating circulating-free DNA (cfDNA) analysis into clinical practice: opportunities and challenges.
Published in:
2022
By:
- García-Pardo, Miguel;
- Makarem, Maisam;
- Li, Janice J. N.;
- Kelly, Deirdre;
- Leighl, Natasha B.
Publication type:
journal article
Family history, obesity, urological factors and diabetic medications and their associations with risk of prostate cancer diagnosis in a large prospective study.
Published in:
2022
By:
- Nair-Shalliker, Visalini;
- Bang, Albert;
- Egger, Sam;
- Yu, Xue Qin;
- Chiam, Karen;
- Steinberg, Julia;
- Patel, Manish I.;
- Banks, Emily;
- O'Connell, Dianne L.;
- Armstrong, Bruce K.;
- Smith, David P.
Publication type:
journal article
Stepwise evolutionary genomics of early-stage lung adenocarcinoma manifesting as pure, heterogeneous and part-solid ground-glass nodules.
Published in:
2022
By:
- Li, Hao;
- Sun, Zewen;
- Xiao, Rongxin;
- Qi, Qingyi;
- Li, Xiao;
- Huang, Haiyan;
- Wang, Xuan;
- Zhou, Jian;
- Wang, Zhenfan;
- Liu, Ke;
- Yin, Ping;
- Yang, Fan;
- Wang, Jun
Publication type:
journal article

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