Works matching IS 00016322 AND DT 2022 AND VI 144 AND IP 3

Results: 13

HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 465, doi. 10.1007/s00401-022-02471-y

By:

Braems, Elke;
Bercier, Valérie;
Van Schoor, Evelien;
Heeren, Kara;
Beckers, Jimmy;
Fumagalli, Laura;
Dedeene, Lieselot;
Moisse, Matthieu;
Geudens, Ilse;
Hersmus, Nicole;
Mehta, Arpan R.;
Selvaraj, Bhuvaneish T.;
Chandran, Siddharthan;
Ho, Ritchie;
Thal, Dietmar R.;
Van Damme, Philip;
Swinnen, Bart;
Van Den Bosch, Ludo

Publication type:

Article

An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 437, doi. 10.1007/s00401-022-02470-z

By:

Bauer, Claudia S.;
Cohen, Rebecca N.;
Sironi, Francesca;
Livesey, Matthew R.;
Gillingwater, Thomas H.;
Highley, J. Robin;
Fillingham, Daniel J.;
Coldicott, Ian;
Smith, Emma F.;
Gibson, Yolanda B.;
Webster, Christopher P.;
Grierson, Andrew J.;
Bendotti, Caterina;
De Vos, Kurt J.

Publication type:

Article

X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 537, doi. 10.1007/s00401-022-02468-7

By:

Volpatti, Jonathan R.;
Ghahramani-Seno, Mehdi M.;
Mansat, Mélanie;
Sabha, Nesrin;
Sarikaya, Ege;
Goodman, Sarah J.;
Chater-Diehl, Eric;
Celik, Alper;
Pannia, Emanuela;
Froment, Carine;
Combes-Soia, Lucie;
Maani, Nika;
Yuki, Kyoko E.;
Chicanne, Gaëtan;
Uusküla-Reimand, Liis;
Monis, Simon;
Alvi, Sana Akhtar;
Genetti, Casie A.;
Payrastre, Bernard;
Beggs, Alan H.

Publication type:

Article

Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 589, doi. 10.1007/s00401-022-02467-8

By:

Sepulveda-Falla, Diego;
Sanchez, Justin S.;
Almeida, Maria Camila;
Boassa, Daniela;
Acosta-Uribe, Juliana;
Vila-Castelar, Clara;
Ramirez-Gomez, Liliana;
Baena, Ana;
Aguillon, David;
Villalba-Moreno, Nelson David;
Littau, Jessica Lisa;
Villegas, Andres;
Beach, Thomas G.;
White III, Charles L.;
Ellisman, Mark;
Krasemann, Susanne;
Glatzel, Markus;
Johnson, Keith A.;
Sperling, Reisa A.;
Reiman, Eric M.

Publication type:

Article

Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 393, doi. 10.1007/s00401-022-02466-9

By:

Van Schoor, Evelien;
Ospitalieri, Simona;
Moonen, Sebastiaan;
Tomé, Sandra O.;
Ronisz, Alicja;
Ok, Orkun;
Weishaupt, Jochen;
Ludolph, Albert C.;
Van Damme, Philip;
Van Den Bosch, Ludo;
Thal, Dietmar Rudolf

Publication type:

Article

Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 565, doi. 10.1007/s00401-022-02464-x

By:

Danilenko, Marina;
Zaka, Masood;
Keeling, Claire;
Crosier, Stephen;
Lyman, Stephanie;
Finetti, Martina;
Williamson, Daniel;
Hussain, Rafiqul;
Coxhead, Jonathan;
Zhou, Peixun;
Hill, Rebecca M.;
Hicks, Debbie;
Rand, Vikki;
Joshi, Abhijit;
Schwalbe, Edward C.;
Bailey, Simon;
Clifford, Steven C.

Publication type:

Article

Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's disease.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 521, doi. 10.1007/s00401-022-02462-z

By:

Lee, Hae Nim;
Hyeon, Seung Jae;
Kim, Heejung;
Sim, Kyoung Mi;
Kim, Yunha;
Ju, Jeongmin;
Lee, Junghee;
Wang, Yingxiao;
Ryu, Hoon;
Seong, Jihye

Publication type:

Article

Cryo-EM structures of prion protein filaments from Gerstmann–Sträussler–Scheinker disease.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 509, doi. 10.1007/s00401-022-02461-0

By:

Hallinan, Grace I.;
Ozcan, Kadir A.;
Hoq, Md Rejaul;
Cracco, Laura;
Vago, Frank S.;
Bharath, Sakshibeedu R.;
Li, Daoyi;
Jacobsen, Max;
Doud, Emma H.;
Mosley, Amber L.;
Fernandez, Anllely;
Garringer, Holly J.;
Jiang, Wen;
Ghetti, Bernardino;
Vidal, Ruben

Publication type:

Article

The Alzheimer's disease GWAS risk alleles in the ABCA7 promoter and 5' region reduce ABCA7 expression.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 585, doi. 10.1007/s00401-022-02459-8

By:

Lyssenko, Nicholas N.;
Shi, Xinghua;
Praticò, Domenico

Publication type:

Article

Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 489, doi. 10.1007/s00401-022-02458-9

By:

Botella Lucena, Pablo;
Vanherle, Sarah;
Lodder, Chritica;
Gutiérrez de Ravé, Manuel;
Stancu, Ilie-Cosmin;
Lambrichts, Ivo;
Vangheluwe, Riet;
Bruffaerts, Rose;
Dewachter, Ilse

Publication type:

Article

Jorge Cervós-Navarro 1930–2021.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 391, doi. 10.1007/s00401-022-02456-x

By:

Stoltenburg-Didinger, Gisela;
Goebel, Hans-Hilmar

Publication type:

Article

Intratumor and informatic heterogeneity influence meningioma molecular classification.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 579, doi. 10.1007/s00401-022-02455-y

By:

Vasudevan, Harish N.;
Choudhury, Abrar;
Hilz, Stephanie;
Villanueva-Meyer, Javier E.;
Chen, William C.;
Lucas, Calixto-Hope G.;
Braunstein, Steve E.;
Oberheim Bush, Nancy Ann;
Butowski, Nicholas;
Pekmezci, Melike;
McDermott, Michael W.;
Perry, Arie;
Solomon, David A.;
Magill, Stephen T.;
Raleigh, David R.

Publication type:

Article

Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 3, p. 413, doi. 10.1007/s00401-022-02450-3

By:

Krach, Florian;
Wheeler, Emily C.;
Regensburger, Martin;
Boerstler, Tom;
Wend, Holger;
Vu, Anthony Q.;
Wang, Ruth;
Reischl, Stephanie;
Boldt, Karsten;
Batra, Ranjan;
Aigner, Stefan;
Ravits, John;
Winkler, Juergen;
Yeo, Gene W.;
Winner, Beate

Publication type:

Article