Works in Acta Neuropathologica, 2025, Vol 149, Issue 1

Results: 47
    1

    Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome–Alzheimer's disease.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02889-0
    By:
    • Farrell, Clíona;
    • Buhidma, Yazead;
    • Mumford, Paige;
    • Heywood, Wendy E.;
    • Hällqvist, Jenny;
    • Flores-Aguilar, Lisi;
    • Andrews, Elizabeth J.;
    • Rahimzadah, Negin;
    • Taso, Orjona Stella;
    • Doran, Eric;
    • Swarup, Vivek;
    • Head, Elizabeth;
    • Lashley, Tammaryn;
    • Mills, Kevin;
    • Toomey, Christina E.;
    • Wiseman, Frances K.
    Publication type:
    Article
    2
    3
    4

    DNA methylation identifies body segment origins of spinal ependymomas.

    Published in:
    2025
    By:
    • Yamazawa, Erika;
    • Tanaka, Shota;
    • Nagae, Genta;
    • Umeda, Takayoshi;
    • Tatsuno, Kenji;
    • Hana, Taijun;
    • Kim, Phyo;
    • Takami, Toshihiro;
    • Takai, Keisuke;
    • Komori, Takashi;
    • Otani, Ryohei;
    • Higuchi, Fumi;
    • Takami, Hirokazu;
    • Yamada, Keisuke;
    • Nomura, Masashi;
    • Mukasa, Akitake;
    • Takayanagi, Shunsaku;
    • Imai, Hideaki;
    • Aburatani, Hiroyuki;
    • Saito, Nobuhito
    Publication type:
    Letter
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    Spatial mapping of the AA-PGE<sub>2</sub>-EP axis in multiple sclerosis lesions.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02878-3
    By:
    • Hansen, Cathrin E.;
    • Konings, Julia;
    • Toth, Gabor;
    • Chornyi, Serhii;
    • Karsten, Manon;
    • van het Hof, Bert;
    • van der Pol, Susanne M. A.;
    • Beekhuis-Hoekstra, Stephanie D.;
    • Kok, Nine;
    • Fung, Wing Ka;
    • Dijksman, Naomi S.;
    • Baron, Wia;
    • Witte, Maarten E.;
    • Lanekoff, Ingela;
    • de Vries, Helga E.;
    • Kooij, Gijs
    Publication type:
    Article
    12

    LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02876-5
    By:
    • Shahidehpour, Ryan K.;
    • Katsumata, Yuriko;
    • Dickson, Dennis W.;
    • Ghayal, Nikhil B.;
    • Aung, Khine Zin;
    • Wu, Xian;
    • Phe, Panhavuth;
    • Jicha, Gregory A.;
    • Neltner, Allison M.;
    • Archer, Jessalin R. C.;
    • Corrada, Maria M.;
    • Kawas, Claudia H.;
    • Ahmad Sajjadi, S.;
    • Woodworth, Davis C.;
    • Bukhari, Syed A.;
    • Montine, Thomas J.;
    • Fardo, David W.;
    • Nelson, Peter T.
    Publication type:
    Article
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    Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02882-7
    By:
    • Di Liberto, Giovanni;
    • Egervari, Kristof;
    • Vogrig, Alberto;
    • Spatola, Marianna;
    • Piccinno, Margot;
    • Vincenti, Ilena;
    • Wagner, Ingrid;
    • Kreutzfeldt, Mario;
    • Endmayr, Verena;
    • Ostertag, Karoline;
    • Rahimi, Jasmin;
    • Vicino, Alex;
    • Pröbstel, Anne-Katrin;
    • Meyronet, David;
    • Frank, Stephan;
    • Prinz, Marco;
    • Hewer, Ekkehard;
    • Brouland, Jean-Philippe;
    • de Leval, Laurence;
    • Parkkinen, Laura
    Publication type:
    Article
    16

    Correction: CSF p-tau205: a biomarker of tau pathology in Alzheimer's disease.

    Published in:
    2025
    By:
    • Lantero-Rodriguez, Juan;
    • Montoliu-Gaya, Laia;
    • Benedet, Andrea L.;
    • Vrillon, Agathe;
    • Dumurgier, Julien;
    • Cognat, Emmanuel;
    • Brum, Wagner S.;
    • Rahmouni, Nesrine;
    • Stevenson, Jenna;
    • Servaes, Stijn;
    • Therriault, Joseph;
    • Becker, Bruno;
    • Brinkmalm, Gunnar;
    • Snellman, Anniina;
    • Huber, Hanna;
    • Kvartsberg, Hlin;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Paquet, Claire;
    • Rosa-Neto, Pedro
    Publication type:
    Correction Notice
    17

    CNS angiocentric stromal tumor (CAST), PDGFRA-mutant, a novel entity histologically mimicking meningioangiomatosis and radiologically correlating with giant Virchow–Robin spaces.

    Published in:
    2025
    By:
    • Guney, Ekin;
    • Mirchia, Kanish;
    • Schmid, Simone;
    • Capper, David;
    • Meinhardt, Jenny;
    • Cha, Soonmee;
    • Lee, Han;
    • Brathwaite, Carole;
    • Altman, Nolan;
    • Sloan, Emily A.;
    • Sayah, Anousheh;
    • McGrail, Kevin;
    • Caliskan, Ilay;
    • Terry, Merryl;
    • Perez, Sandra;
    • Bollen, Andrew W.;
    • Tihan, Tarik;
    • Pekmezci, Melike;
    • Perry, Arie
    Publication type:
    Letter
    18

    Diffuse astrocytoma, AYA-type, frequently MAPK-altered: report of 45 patients.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02873-8
    By:
    • Singh, Omkar;
    • Dampier, Christopher;
    • Abdullaev, Zied;
    • Dazelle, Karen;
    • Chung, Hye-Jung;
    • Conway, Kyle;
    • Camelo-Piragua, Sandra;
    • Neill, Stewart;
    • Brown, Daniel;
    • Nix, James Stephen;
    • Giannini, Caterina;
    • Macaulay, Robert;
    • Marker, Daniel;
    • Skaugen, John;
    • Kulich, Scott;
    • Lee, Han;
    • Aboud, Orwa;
    • Pytel, Peter;
    • Borys, Ewa;
    • Perry, Arie
    Publication type:
    Article
    19

    Seeding-competent early tau multimers are associated with cell type-specific transcriptional signatures.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02869-4
    By:
    • Feleke, Rahel;
    • Jogaudaite, Simona;
    • Velentza-Almpani, Elisavet;
    • Yeung-Yeung, Leung;
    • Clode, Daniel;
    • Ko, Jeong Hun;
    • Shin, Ben;
    • Matthews, Steve;
    • Otero-Jimenez, Maria;
    • Wojewska, Marcelina J.;
    • Gray-Rodriguez, Sandra;
    • Marzi, Sarah J.;
    • Spires-Jones, Maxwell P.;
    • Spires-Jones, Tara L.;
    • Johnson, Michael R.;
    • Alegre-Abarrategui, Javier
    Publication type:
    Article
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    Biofluid-based staging of Alzheimer's disease.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02863-w
    By:
    • Lantero-Rodriguez, Juan;
    • Montoliu-Gaya, Laia;
    • Ashton, Nicholas J.;
    • Pola, Ilaria;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Brum, Wagner S.;
    • Servaes, Stijn;
    • Stevenson, Jenna;
    • Di Molfetta, Guglielmo;
    • Arslan, Burak;
    • Klostranec, Jesse;
    • Vitali, Paolo;
    • Montembeault, Maxime;
    • Gauthier, Serge;
    • Tissot, Cecile;
    • Macedo, Arthur C.;
    • Pascoal, Tharick A.;
    • Jeromin, Andreas;
    • Gobom, Johan
    Publication type:
    Article
    24

    High resolution autoradiography of [<sup>18</sup>F]MK-6240 and [<sup>18</sup>F]Flortaucipir shows similar neurofibrillary tangle binding patterns preferentially recognizing middling neurofibrillary tangle maturity.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02864-9
    By:
    • Ghatamaneni, Sujala;
    • Coleman, Courtney;
    • Shin, Ian;
    • Bruinsma, Tyler;
    • Scott, Nancy;
    • Lee, Jeyeon;
    • Fang, Ping;
    • Min, Hoon-Ki;
    • Moloney, Christina M.;
    • Wood, Ashley C.;
    • Constantopoulos, Eleni;
    • Reichard, Ross R.;
    • Schwarz, Christopher G.;
    • Jones, David T.;
    • Graff-Radford, Jonathan;
    • Knopman, David S.;
    • Jack Jr., Clifford R.;
    • Petersen, Ronald C.;
    • Dickson, Dennis W.;
    • Murray, Melissa E.
    Publication type:
    Article
    25

    Constitutional variants in PTEN: a frequent finding in patients with papillary tumors of the pineal region subtype B (PTPR-B) associated with isolated loss of chromosome 10.

    Published in:
    2025
    By:
    • Hirsch, Steffen;
    • Rahmanzade, Ramin;
    • Grund, Kerstin;
    • Sutter, Christian;
    • Schramm, Kathrin;
    • Selt, Florian;
    • Ecker, Jonas;
    • Jones, Barbara C.;
    • Schrimpf, Daniel;
    • Demmert, Martin;
    • Guerreiro Stücklin, Ana S.;
    • Hernaiz Driever, Pablo;
    • Mezger, Markus;
    • Brecht, Ines;
    • Adib, Sasan D.;
    • Brummel, Bastian;
    • Sturm, Dominik;
    • Dikow, Nicola;
    • Hempel, Maja;
    • Milde, Till
    Publication type:
    Letter
    26

    High resolution autoradiography of [<sup>18</sup>F]MK-6240 and [<sup>18</sup>F]Flortaucipir shows similar neurofibrillary tangle binding patterns preferentially recognizing middling neurofibrillary tangle maturity.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02864-9
    By:
    • Ghatamaneni, Sujala;
    • Hruska, Courtney;
    • Shin, Ian;
    • Bruinsma, Tyler;
    • Scott, Nancy;
    • Lee, Jeyeon;
    • Fang, Ping;
    • Min, Hoon-Ki;
    • Moloney, Christina M.;
    • Wood, Ashley C.;
    • Constantopoulos, Eleni;
    • Reichard, Ross R.;
    • Schwarz, Christopher G.;
    • Jones, David T.;
    • Graff-Radford, Jonathan;
    • Knopman, David S.;
    • Jack Jr., Clifford R.;
    • Petersen, Ronald C.;
    • Dickson, Dennis W.;
    • Murray, Melissa E.
    Publication type:
    Article
    27

    Characterizing white matter and vascular pathologies in brain donors exposed to repetitive head impacts.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02860-z
    By:
    • Emrani, Sheina;
    • Koutures, Anne;
    • Tripodis, Yorghos;
    • Uretsky, Madeline;
    • Abdolmohammadi, Bobak;
    • Nowinski, Christopher;
    • Daneshvar, Daniel H.;
    • Dwyer, Brigid;
    • Katz, Douglas I.;
    • Goldstein, Lee E.;
    • Cantu, Robert C.;
    • Martin, Brett M.;
    • Palmisano, Joseph N.;
    • Dams-O'Connor, Kristen;
    • Crary, John F.;
    • Stern, Robert A.;
    • Mez, Jesse;
    • Alvarez, Victor E.;
    • Huber, Bertrand R.;
    • McKee, Ann C.
    Publication type:
    Article
    28

    Parkinson-like wild-type superoxide dismutase 1 pathology induces nigral dopamine neuron degeneration in a novel murine model.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02859-6
    By:
    • Abdeen, Amr H.;
    • Trist, Benjamin G.;
    • Nikseresht, Sara;
    • Harwood, Richard;
    • Roudeau, Stéphane;
    • Rowlands, Benjamin D.;
    • Kreilaus, Fabian;
    • Cottam, Veronica;
    • Mor, David;
    • Richardson, Miriam;
    • Siciliano, Joel;
    • Forkgen, Julia;
    • Schaffer, Greta;
    • Genoud, Sian;
    • Li, Anne A.;
    • Proschogo, Nicholas;
    • Antonio, Bernadeth;
    • Falkenberg, Gerald;
    • Brueckner, Dennis;
    • Kysenius, Kai
    Publication type:
    Article
    29

    Human brain tissue with MOGHE carrying somatic SLC35A2 variants reveal aberrant protein expression and protein loss in the white matter.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02858-7
    By:
    • Cecchini, Erica;
    • Geffers, Simon;
    • Coras, Roland;
    • Schultheis, Dorothea;
    • Holtzhausen, Christian;
    • Karandasheva, Kristina;
    • Herrmann, Harald;
    • Paulsen, Friedrich;
    • Stadelmann, Christine;
    • Kobow, Katja;
    • Hartlieb, Till;
    • Bien, Christian G.;
    • Lal, Dennis;
    • Blumcke, Ingmar;
    • Hoffmann, Lucas
    Publication type:
    Article
    30

    Evidence of COMT dysfunction in the olfactory bulb in Parkinson's disease.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02861-y
    By:
    • Beauchamp, Leah C.;
    • Ellett, Laura J.;
    • Juan, Sydney M. A.;
    • Liu, Xiang M.;
    • Hunt, Cameron P. J.;
    • Parish, Clare L.;
    • Jacobson, Laura H.;
    • Shepherd, Claire E.;
    • Halliday, Glenda M.;
    • Bush, Ashley I.;
    • Vella, Laura J.;
    • Finkelstein, David I.;
    • Barnham, Kevin J.
    Publication type:
    Article
    31

    A quantitative Lewy-fold-specific alpha-synuclein seed amplification assay as a progression marker for Parkinson's disease.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02853-y
    By:
    • Bernhardt, Alexander M.;
    • Longen, Sebastian;
    • Trossbach, Svenja V.;
    • Rossi, Marcello;
    • Weckbecker, Daniel;
    • Schmidt, Felix;
    • Jäck, Alexander;
    • Katzdobler, Sabrina;
    • Fietzek, Urban M.;
    • Weidinger, Endy;
    • Palleis, Carla;
    • Ruf, Viktoria;
    • Baiardi, Simone;
    • Parchi, Piero;
    • Höglinger, Günter U.;
    • Matthias, Torsten;
    • Levin, Johannes;
    • Giese, Armin
    Publication type:
    Article
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    Somatic variants in SLC35A2 leading to defects in N-glycosylation in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE).

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02850-1
    By:
    • Liu, Xianyu;
    • Tang, Qi;
    • Xia, Xiaoqian;
    • Liu, Qingzhu;
    • Liu, Jialin;
    • Jin, Yangyanan;
    • Wu, Pengxia;
    • Luo, Huaxia;
    • Gao, Kai;
    • Ruan, Xiaoqin;
    • Sun, Yu;
    • Ji, Taoyun;
    • Wang, Shuang;
    • Liu, Xiaoyan;
    • Cai, Lixin;
    • Jiang, Yuwu;
    • Dai, Peng;
    • Chen, Xing;
    • Wu, Ye
    Publication type:
    Article
    39

    IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02849-8
    By:
    • Hinz, Felix;
    • Friedel, Dennis;
    • Korshunov, Andrey;
    • Ippen, Franziska M.;
    • Bogumil, Henri;
    • Banan, Rouzbeh;
    • Brandner, Sebastian;
    • Hasselblatt, Martin;
    • Boldt, Henning B.;
    • Dirse, Vaidas;
    • Dohmen, Hildegard;
    • Aronica, Eleonora;
    • Brodhun, Michael;
    • Broekman, Marike L. D.;
    • Capper, David;
    • Cherkezov, Asan;
    • Deng, Maximilian Y.;
    • van Dis, Vera;
    • Felsberg, Jörg;
    • Frank, Stephan
    Publication type:
    Article
    40

    MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02846-x
    By:
    • Friker, Lea L.;
    • Perwein, Thomas;
    • Waha, Andreas;
    • Dörner, Evelyn;
    • Klein, Rebecca;
    • Blattner-Johnson, Mirjam;
    • Layer, Julian P.;
    • Sturm, Dominik;
    • Nussbaumer, Gunther;
    • Kwiecien, Robert;
    • Spier, Isabel;
    • Aretz, Stefan;
    • Kerl, Kornelius;
    • Hennewig, Ulrike;
    • Rohde, Marius;
    • Karow, Axel;
    • Bluemcke, Ingmar;
    • Schmitz, Ann Kristin;
    • Reinhard, Harald;
    • Hernáiz Driever, Pablo
    Publication type:
    Article
    41
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    Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02845-y
    By:
    • Pagani, Francesca;
    • Orzan, Francesca;
    • Lago, Sara;
    • De Bacco, Francesca;
    • Prelli, Marta;
    • Cominelli, Manuela;
    • Somenza, Elena;
    • Gryzik, Magdalena;
    • Balzarini, Piera;
    • Ceresa, Davide;
    • Marubbi, Daniela;
    • Isella, Claudio;
    • Crisafulli, Giovanni;
    • Poli, Maura;
    • Malatesta, Paolo;
    • Galli, Rossella;
    • Ronca, Roberto;
    • Zippo, Alessio;
    • Boccaccio, Carla;
    • Poliani, Pietro Luigi
    Publication type:
    Article
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    Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method.

    Published in:
    Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-024-02842-7
    By:
    • Madlener, Sibylle;
    • Stepien, Natalia;
    • Senfter, Daniel;
    • Mayr, Lisa;
    • Laemmerer, Anna;
    • Hedrich, Cora;
    • Baumgartner, Alicia;
    • Lötsch-Gojo, Daniela;
    • Sterba, Jaroslav;
    • Pokorna, Petra;
    • Kiesel, Barbara;
    • Widhalm, Georg;
    • Eckert, Franziska;
    • Preusser, Matthias;
    • Rössler, Karl;
    • Azizi, Amedeo;
    • Peyrl, Andreas;
    • Czech, Thomas;
    • Haberler, Christine;
    • Slavc, Irene
    Publication type:
    Article
    47

    Correction: Genome‑wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors.

    Published in:
    2025
    By:
    • Jotanovic, Jelena;
    • Boldt, Henning Bünsow;
    • Burton, Mark;
    • Andersen, Marianne Skovsager;
    • Bengtsson, Daniel;
    • Bontell, Thomas Olsson;
    • Ekman, Bertil;
    • Engström, Britt Edén;
    • Feldt-Rasmussen, Ulla;
    • Heck, Ansgar;
    • Jakovcevic, Antonia;
    • Jørgensen, Jens Otto L.;
    • Kraljevic, Ivana;
    • Kunicki, Jacek;
    • Lindsay, John R.;
    • Losa, Marco;
    • Loughrey, Paul Benjamin;
    • Maiter, Dominique;
    • Maksymowicz, Maria;
    • Manojlovic-Gacic, Emilija
    Publication type:
    Correction Notice