Works matching Hirano Toshio

Results: 72

Interview with Dr Toshio Hirano.

Published in:: International Immunology, 2021, v. 33, n. 12, p. 623, doi. 10.1093/intimm/dxab084
Publication type:: Article

Developmental fates of larval tissues after metamorphosis in the ascidian, Halocynthia roretzi: II. Origin of endodermal tissues of the juvenile.

Published in:

Development Genes & Evolution, 2000, v. 210, n. 2, p. 55, doi. 10.1007/s004270050011

By:

Hirano, Toshio;
Nishida, Hiroki

Publication type:

Article

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin.

Published in:

Nature, 1986, v. 324, n. 6092, p. 73, doi. 10.1038/324073a0

By:

Hirano, Toshio;
Yasukawa, Kiyoshi;
Harada, Hisashi;
Taga, Tetsuya;
Watanabe, Yasuo;
Matsuda, Tadashi;
Kashiwamura, Shin-ichiro;
Nakajima, Koichi;
Koyama, Koichi;
Iwamatsu, Akihiro;
Tsunasawa, Susumu;
Sakiyama, Fumio;
Matsui, Hiroshi;
Takahara, Yoshiyuki;
Taniguchi, Tadatsugu;
Kishimoto, Tadamitsu

Publication type:

Article

Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses.

Published in:

Nature Immunology, 2008, v. 9, n. 1, p. 81, doi. 10.1038/ni1546

By:

Baba, Yoshihiro;
Nishida, Keigo;
Fujii, Yoko;
Hirano, Toshio;
Hikida, Masaki;
Kurosaki, Tomohiro

Publication type:

Article

Toll-like receptor–mediated regulation of zinc homeostasis influences dendritic cell function.

Published in:

Nature Immunology, 2006, v. 7, n. 9, p. 971, doi. 10.1038/ni1373

By:

Kitamura, Hidemitsu;
Morikawa, Hideyuki;
Kamon, Hokuto;
Iguchi, Megumi;
Hojyo, Shintaro;
Fukada, Toshiyuki;
Yamashita, Susumu;
Kaisho, Tsuneyasu;
Akira, Shizuo;
Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages.

Published in:

Nature Immunology, 2003, v. 4, n. 6, p. 551, doi. 10.1038/ni938

By:

Yasukawa, Hideo;
Ohishi, Masanobu;
Mori, Hiroyuki;
Murakami, Masaaki;
Chinen, Takatoshi;
Aki, Daisuke;
Hanada, Toshikatsu;
Takeda, Kiyoshi;
Akira, Shizuo;
Hoshijima, Masahiko;
Hirano, Toshio;
Chien, Kenneth R;
Yoshimura, Akihiko

Publication type:

Article

Revival of the autoantibody model in rheumatoid arthritis.

Published in:

Nature Immunology, 2002, v. 3, n. 4, p. 342, doi. 10.1038/ni0402-342

By:

Hirano, Toshio

Publication type:

Article

Signal TransductionThrough Cytokine Receptors.

Published in:

International Reviews of Immunology, 1998, v. 17, n. 1-4, p. 75, doi. 10.3109/08830189809084488

By:

Hibi, Masahiko;
Hirano, Toshio

Publication type:

Article

Interleukin 6 and its Receptor: Ten Years Later.

Published in:

International Reviews of Immunology, 1998, v. 16, n. 3/4, p. 249, doi. 10.3109/08830189809042997

By:

Hirano, Toshio

Publication type:

Article

Current Concepts of B Cell Modulation.

Published in:

International Reviews of Immunology, 1989, v. 5, n. 2, p. 97, doi. 10.3109/08830188909061976

By:

Matsuda, Tadashi;
Yamasaki, Katsuhiko;
Taga, Tetsuya;
Hirano, Toshio;
Kishimoto, Tadamitsu

Publication type:

Article

A new interleukin with pleiotropic activities.

Published in:

BioEssays, 1988, v. 9, n. 1, p. 11, doi. 10.1002/bies.950090104

By:

Kishimoto, Tadamitsu;
Hirano, Toshio

Publication type:

Article

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition.

Published in:

EMBO Journal, 1998, v. 17, n. 22, p. 6670, doi. 10.1093/emboj/17.22.6670

By:

Fukada, Toshiyuki;
Ohtani, Takuya;
Yoshida, Yuichi;
Shirogane, Takahiro;
Nishida, Keigo;
Nakajima, Koichi;
Hibi, Masahiko;
Hirano, Toshio

Publication type:

Article

Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1.

Published in:

EMBO Journal, 1997, v. 16, n. 23, p. 7067, doi. 10.1093/emboj/16.23.7067

By:

Sekimoto, Toshihiro;
Imamoto, Naoko;
Nakajima, Koichi;
Hirano, Toshio;
Yoneda, Yoshihiro

Publication type:

Article

Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

Published in:

EMBO Journal, 1997, v. 16, n. 17, p. 5345, doi. 10.1093/emboj/16.17.5345

By:

Ihara, Sayoko;
Nakajima, Koichi;
Fukada, Toshiyuki;
Hibi, Masahiko;
Nagata, Satoshi;
Hirano, Toshio;
Fukui, Yasuhisa

Publication type:

Article

Renin–angiotensin system inhibitors and the severity of coronavirus disease 2019 in Kanagawa, Japan: a retrospective cohort study.

Published in:

Hypertension Research, 2020, v. 43, n. 11, p. 1257, doi. 10.1038/s41440-020-00535-8

By:

Matsuzawa, Yasushi;
Ogawa, Hisao;
Kimura, Kazuo;
Konishi, Masaaki;
Kirigaya, Jin;
Fukui, Kazuki;
Tsukahara, Kengo;
Shimizu, Hiroyuki;
Iwabuchi, Keisuke;
Yamada, Yu;
Saka, Kenichiro;
Takeuchi, Ichiro;
Hirano, Toshio;
Tamura, Kouichi

Publication type:

Article

Intracellular zinc homeostasis and zinc signaling.

Published in:

Cancer Science, 2008, v. 99, n. 8, p. 1515, doi. 10.1111/j.1349-7006.2008.00854.x

By:

Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.

Published in:

Cancer Science, 2007, v. 98, n. 5, p. 692, doi. 10.1111/j.1349-7006.2007.00446.x

By:

Kagara, Naofumi;
Tanaka, Natsumi;
Noguchi, Shinzaburo;
Hirano, Toshio

Publication type:

Article

The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors.

Published in:

Cancer Science, 2003, v. 94, n. 12, p. 1029, doi. 10.1111/j.1349-7006.2003.tb01396.x

By:

Nishida, Keigo;
Hirano, Toshio

Publication type:

Article

Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer.

Published in:

Nature, 2004, v. 429, n. 6989, p. 298, doi. 10.1038/nature02545

By:

Yamashita, Susumu;
Miyagi, Chiemi;
Fukada, Toshiyuki;
Kagara, Naofumi;
Yong-Suk Che;
Hirano, Toshio

Publication type:

Article

Revisiting the 1986 molecular cloning of interleukin 6.

Published in:

Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00456

By:

Toshio Hirano

Publication type:

Article

The molecular mechanisms of chronic inflammation development.

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00323

By:

Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

The Molecular Mechanisms of Chronic Inflammation Development.

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00323

By:

Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

Gab-Family Adapter Molecules in Signal Transduction of Cytokine and Growth Factor Receptors,....

Published in:

Leukemia & Lymphoma, 2000, v. 37, n. 3/4, p. 299, doi. 10.3109/10428190009089430

By:

Hibi, Masahiko;
Hirano, Toshio

Publication type:

Article

Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.

Published in:

Journal of Clinical Investigation, 2007, v. 117, p. 1771, doi. 10.1172/JCI30651

By:

Nakaoka, Yoshikazu;
Nishida, Keigo;
Narimatsu, Masahiro;
Kamiya, Atsunori;
Minami, Takashi;
Sawa, Hirofumi;
Okawa, Katsuya;
Fujio, Yasushi;
Koyama, Tatsuya;
Maeda, Makiko;
Sone, Manami;
Yamasaki, Satoru;
Arai, Yuji;
Gou Young Koh;
Kodama, Tatsuhiko;
Hirota, Hisao;
Otsu, Kinya;
Hirano, Toshio;
Mochizuki, Naoki

Publication type:

Article

Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 7, p. 1771, doi. 10.1172/JCI30651

By:

Nakaoka, Yoshikazu;
Nishida, Keigo;
Narimatsu, Masahiro;
Kamiya, Atsunori;
Minami, Takashi;
Sawa, Hirofumi;
Okawa, Katsuya;
Fujio, Yasushi;
Koyama, Tatsuya;
Maeda, Makiko;
Sone, Manami;
Yamasaki, Satoru;
Arai, Yuji;
Gou Young Koh;
Kodama, Tatsuhiko;
Hirota, Hisao;
Otsu, Kinya;
Hirano, Toshio;
Mochizuki, Naoki

Publication type:

Article

Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.

Published in:

2007

By:

Khiong, Khie;
Murakami, Masaaki;
Kitabayashi, Chika;
Ueda, Naoko;
Sawa, Shin-ichiro;
Sakamoto, Akemi;
Kotzin, Brian L;
Rozzo, Stephen J;
Ishihara, Katsuhiko;
Verella-Garcia, Marileila;
Kappler, John;
Marrack, Philippa;
Hirano, Toshio

Publication type:

journal article

Homeostatically proliferating CD4+ T cells are involved in the pathogenesis of an Omenn syndrome murine model.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 5, p. 1270, doi. 10.1172/JCI30513

By:

Khie Khiong;
Murakami, Masaaki;
Kitabayashi, Chika;
Ueda, Naoko;
Sawa, Shin-ichiro;
Sakamoto, Akemi;
Kotzin, Brian L.;
Rozzo, Stephen J.;
Ishihara, Katsuhiko;
Verella-Garcia, Marileila;
Kappler, John;
Marrack, Philippa;
Hirano, Toshio

Publication type:

Article

IL-6 in inflammation, autoimmunity and cancer.

Published in:

International Immunology, 2021, v. 33, n. 3, p. 127, doi. 10.1093/intimm/dxaa078

By:

Hirano, Toshio

Publication type:

Article

IL-6 amplifier activation in epithelial regions of bronchi after allogeneic lung transplantation.

Published in:

International Immunology, 2013, v. 25, n. 5, p. 319, doi. 10.1093/intimm/dxs158

By:

Lee, Jihye;
Nakagiri, Tomoyuki;
Kamimura, Daisuke;
Harada, Masaya;
Oto, Takahiro;
Susaki, Yoshiyuki;
Shintani, Yasushi;
Inoue, Masayoshi;
Miyoshi, Shinichiro;
Morii, Eiichi;
Hirano, Toshio;
Murakami, Masaaki;
Okumura, Meinoshin

Publication type:

Article

HIV-induced B Cell Stimulatory Factor 2/Interleukin-6 (BSF2/IL6) Productiona.

Published in:

Annals of the New York Academy of Sciences, 1989, v. 557, n. 1, p. 521, doi. 10.1111/j.1749-6632.1989.tb24052.x

By:

NAKAJIMA, KOICHI;
MARTINEZ-MAZA, OTONIEL;
HIRANO, TOSHIO;
BREEN, ELIZABETH C.;
NISHANIAN, PARUNAG G.;
SALAZAR-GONZALEZ, JESUS F.;
FAHEY, JOHN L.;
KISHIMOTO, TADAMITSU

Publication type:

Article

Molecular Regulation of the Human Immunoglobulin γ1 Heavy Chain Gene by IL-6.

Published in:

Annals of the New York Academy of Sciences, 1989, v. 557, n. 1, p. 552, doi. 10.1111/j.1749-6632.1989.tb24063.x

By:

RAYNAL, MARIE-CECILE;
HIRANO, TOSHIO;
MAYER, LLOYD;
KISHIMOTO, TADAMITSU;
CHEN-KIANGa, SELINA

Publication type:

Article

Zinc is a novel intracellular second messenger.

Published in:

Journal of Cell Biology, 2007, v. 177, n. 4, p. 637, doi. 10.1083/jcb.200702081

By:

Yamasaki, Satoru;
Sakata-Sogawa, Kumiko;
Hasegawa, Aiko;
Suzuki, Tomoyuki;
Kabu, Koki;
Sato, Emi;
Kurosaki, Tomohiro;
Yamashita, Susumu;
Tokunaga, Makio;
Nishida, Keigo;
Hirano, Toshio

Publication type:

Article

STAT3 noncell-autonomously controls planar cell polarity during zebrafish convergence and extension.

Published in:

Journal of Cell Biology, 2004, v. 166, n. 7, p. 975, doi. 10.1083/jcb.200403110

By:

Miyagi, Chiemi;
Yamashita, Susumu;
Ohba, Yusuke;
Yoshizaki, Hisayoshi;
Matsuda, Michiyuki;
Hirano, Toshio

Publication type:

Article

Gab11 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation.

Published in:

Journal of Cell Biology, 2002, v. 159, n. 1, p. 103, doi. 10.1083/jcb.200205017

By:

Ti Cai;
Nishida, Keigo;
Hirano, Toshio;
Khavari, Paul A.

Publication type:

Article

V- ABL does not abolish IL-6 requirement by murine plasmacytoma cells.

Published in:

International Journal of Cancer, 1991, v. 48, n. 2, p. 234, doi. 10.1002/ijc.2910480214

By:

Sugiyama, Hiroyuki;
Wiener, Francis;
Babonits, Magda;
Silva, Santiago;
Hirano, Toshio;
Kishimoto, Tadamitsu;
Klein, George

Publication type:

Article

How COVID-19 induces cytokine storm with high mortality.

Published in:

Inflammation & Regeneration, 2020, v. 40, n. 1, p. N.PAG, doi. 10.1186/s41232-020-00146-3

By:

Hojyo, Shintaro;
Uchida, Mona;
Tanaka, Kumiko;
Hasebe, Rie;
Tanaka, Yuki;
Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK.

Published in:

Oncogene, 1997, v. 14, n. 19, p. 2273, doi. 10.1038/sj.onc.1201071

By:

Takahashi-Tezuka, Mariko;
Hibi, Masahiko;
Fujitani, Yoshio;
Fukada, Toshiyuki;
Yamaguchi, Takuya;
Hirano, Toshio

Publication type:

Article

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

Published in:

Oncogene, 1997, v. 14, n. 7, p. 751, doi. 10.1038/sj.onc.1200907

By:

Fujitani, Yoshio;
Hibi, Masahiko;
Fukada, Toshiyuki;
Takahashi-Tezuka, Mariko;
Yoshida, Hideyuki;
Yamaguchi, Takuya;
Sugiyama, Kenji;
Yamanaka, Yojiro;
Nakajima, Koichi;
Hirano, Toshio

Publication type:

Article

Tyrosine dephosphorylation of STAT3 in SARS coronavirus-infected Vero E6 cells

Published in:

FEBS Letters, 2004, v. 577, n. 1/2, p. 187, doi. 10.1016/j.febslet.2004.10.005

By:

Mizutani, Tetsuya;
Fukushi, Shuetsu;
Murakami, Masaaki;
Hirano, Toshio;
Saijo, Masayuki;
Kurane, Ichiro;
Morikawa, Shigeru

Publication type:

Article

c-Cbl-Dependent Monoubiquitination and Lysosomal Degradation of gp130.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 15, p. 4805, doi. 10.1128/MCB.01784-07

By:

Tanaka, Yoshinori;
Tanaka, Nobuyuki;
Saeki, Yasushi;
Tanaka, Keiji;
Murakami, Masaaki;
Hirano, Toshio;
Ishii, Naoto;
Sugamura, Kazuo

Publication type:

Article

Enhanced Expression of Interleukin-6 in Primary Human Renal Cell Carcinomas.

Published in:

JNCI: Journal of the National Cancer Institute, 1991, v. 83, n. 22, p. 1668

By:

Takenawa, Jun;
Kaneko, Yoshiyuki;
Fukumoto, Manabu;
Fukatsu, Atsushi;
Hirano, Toshio;
Fukuyama, Hidenao;
Nakayama, Hiroki;
Fujita, Jun;
Yoshida, Osamu

Publication type:

Article

Zinc suppresses Th17 development via inhibition of STAT3 activation.

Published in:

International Immunology, 2010, v. 22, n. 5, p. 375, doi. 10.1093/intimm/dxq017

By:

Kitabayashi, Chika;
Fukada, Toshiyuki;
Kanamoto, Minoru;
Ohashi, Wakana;
Hojyo, Shintaro;
Atsumi, Toru;
Ueda, Naoko;
Azuma, Ichiro;
Hirota, Hiroshi;
Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

IL-6 positively regulates Foxp3+CD8+ T cells in vivo.

Published in:

International Immunology, 2010, v. 22, n. 2, p. 129, doi. 10.1093/intimm/dxp119

By:

Nakagawa, Takayuki;
Tsuruoka, Mineko;
Ogura, Hideki;
Okuyama, Yuko;
Arima, Yasunobu;
Hirano, Toshio;
Murakami, Masaaki

Publication type:

Article

IFN-{gamma} expression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death.

Published in:

International Immunology, 2009, v. 21, n. 1, p. 73, doi. 10.1093/intimm/dxn125

By:

Toru Atsumi;
Masae Sato;
Daisuke Kamimura;
Arisa Moroi;
Yoichiro Iwakura;
Ulrich A. K. Betz;
Akihiko Yoshimura;
Mika Nishihara;
Toshio Hirano;
Masaaki Murakami

Publication type:

Article

Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation.

Published in:

International Immunology, 2008, v. 20, n. 6, p. 783, doi. 10.1093/intimm/dxn036

By:

Gui-Hua Jin;
Toshio Hirano;
Masaaki Murakami

Publication type:

Article

IL-6–gp130–STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.

Published in:

International Immunology, 2007, v. 19, n. 6, p. 695, doi. 10.1093/intimm/dxm045

By:

Nishihara, Mika;
Ogura, Hideki;
Ueda, Naoko;
Tsuruoka, Mineko;
Kitabayashi, Chika;
Tsuji, Fumio;
Aono, Hiroyuki;
Ishihara, Katsuhiko;
Huseby, Eric;
Betz, Ulrich A. K.;
Murakami, Masaaki;
Hirano, Toshio

Publication type:

Article

CD1d-restricted NKT cell activation enhanced homeostatic proliferation of CD8+ T cells in a manner dependent on IL-4.

Published in:

International Immunology, 2006, v. 18, n. 9, p. 1397, doi. 10.1093/intimm/dxl073

By:

Naoko Ueda;
Hiroko Kuki;
Daisuke Kamimura;
Shinichiro Sawa;
Kenichiro Seino;
Takuya Tashiro;
Ken-ichi Fushuku;
Masaru Taniguchi;
Toshio Hirano;
Masaaki Murakami

Publication type:

Article

The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.

Published in:

International Immunology, 2004, v. 16, n. 3, p. 455, doi. 10.1093/intimm/dxh045

By:

Katsuhiko Ishihara;
Shin-ichiro Sawa;
Hideto Ikushima;
Seiichi Hirota;
Toru Atsumi;
Daisuke Kamimura;
Sung-Joo Park;
Masaaki Murakami;
Yukihiko Kitamura;
Yoichiro Iwakura;
Toshio Hirano

Publication type:

Article

Stage-specific expression of mouse BST-1/BP-3 on the early B and T cell progenitors prior to gene rearrangement of antigen receptor.

Published in:

International Immunology, 1996, v. 8, n. 9, p. 1395, doi. 10.1093/intimm/8.9.1395

By:

Katsuhiko Ishihara;
Yoshiko Kobune;
Yoshiki Okuyama;
Motoyuki Itoh;
Byung O. K. Lee;
Osamu Muraoka;
Toshio Hirano

Publication type:

Article

Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2.

Published in:

Oncogene, 2003, v. 22, n. 10, p. 1546, doi. 10.1038/sj.onc.1206284

By:

Yamasaki, Satoru;
Nishida, Keigo;
Yoshida, Yuichi;
Itoh, Motoyuki;
Hibi, Masahiko;
Hirano, Toshio

Publication type:

Article