Works matching HRAS genes

Results: 259

Predicting Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) of HRAS Gene and In Silico Evaluation of Their Structural and Functional Consequences towards Diagnosis and Prognosis of Cancer.

Published in:

Biology (2079-7737), 2022, v. 11, n. 11, p. 1604, doi. 10.3390/biology11111604

By:

Chai, Chuan-Yu;
Maran, Sathiya;
Thew, Hin-Yee;
Tan, Yong-Chiang;
Rahman, Nik Mohd Afizan Nik Abd;
Cheng, Wan-Hee;
Lai, Kok-Song;
Loh, Jiun-Yan;
Yap, Wai-Sum

Publication type:

Article

Methylation pattern of oncogene HRAS gene promoter region and its clinical relevance to urocystic tumorigenesis.

Published in:

Molecular Biology Reports, 2012, v. 39, n. 8, p. 8431, doi. 10.1007/s11033-012-1696-7

By:

Sun, Xiao-Feng;
Li, Lan;
Li, Xiu-Juan;
Shen, Wei

Publication type:

Article

Clinical significance of HRAS and KRAS genes expression in patients with non-small-cell lung cancer - preliminary findings.

Published in:

2021

By:

Pązik, Milena;
Michalska, Katarzyna;
Żebrowska-Nawrocka, Marta;
Zawadzka, Izabela;
Łochowski, Mariusz;
Balcerczak, Ewa

Publication type:

journal article

Costello syndrome.

Published in:: Anaesthesiologie & Intensivmedizin, 2021, v. 62, p. 1, doi. 10.19224/ai2021.S075
Publication type:: Article

Reduced HRAS<sup>G12V</sup>-Driven Tumorigenesis of Cell Lines Expressing KRAS<sup>C118S</sup>.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123918

By:

Huang, Lu;
Counter, Christopher M.

Publication type:

Article

Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment.

Published in:

Case Reports in Pediatrics, 2015, v. 2015, p. 1, doi. 10.1155/2015/934865

By:

Sriboonnark, Leelawadee;
Arora, Harleen;
Falto-Aizpurua, Leyre;
Choudhary, Sonal;
Connelly, Elizabeth Alvarez

Publication type:

Article

Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04128-5

By:

Geyer, Felipe C.;
Anqi Li;
Papanastasiou, Anastasios D.;
Smith, Alison;
Selenica, Pier;
Burke, Kathleen A.;
Edelweiss, Marcia;
Huei-Chi Wen;
Piscuoglio, Salvatore;
Schultheis, Anne M.;
Martelotto, Luciano G.;
Pareja, Fresia;
Kumar, Rahul;
Brandes, Alissa;
Dan Fan;
Basili, Thais;
Da Cruz Paula, Arnaud;
Lozada, John R.;
Blecua, Pedro;
Muenst, Simone

Publication type:

Article

RAS Mutations in Benign Epithelial Tumors Associated with BRAF Inhibitor Treatment of Melanoma.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 2, p. 636, doi. 10.1038/jid.2014.360

By:

Hassel, Jessica C;
Groesser, Leopold;
Herschberger, Eva;
Weichert, Wilko;
Hafner, Christian

Publication type:

Article

MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.

Published in:

eLife, 2015, p. 1, doi. 10.7554/eLife.07004

By:

Riemondy, Kent;
Xiao-jing Wang;
Torchia, Enrique C.;
Roop, Dennis R.;
Rui Yi

Publication type:

Article

De novo HRAS gene mutation associated with Costello syndrome identified by non‐invasive cell‐free fetal DNA screening.

Published in:

Prenatal Diagnosis, 2021, v. 41, n. 1, p. 11, doi. 10.1002/pd.5798

By:

Nwakalor, Chidinma;
Said‐Delgado, Sara;
Krinshpun, Shifra;
Velinov, Milen

Publication type:

Article

Identification of a novel HRAS variant and its association with papillary thyroid carcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 4, p. 4511, doi. 10.3892/ol.2018.7818

By:

Dou, Rui;
Zhang, Lili;
Lu, Tingxia;
Liu, Dong;
Mei, Fang;
Huang, Jian;
Qian, Linxue

Publication type:

Article

Diagnosis, clinicopathological characteristics and prognosis of pulmonary mucinous adenocarcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 1, p. 489, doi. 10.3892/ol.2017.7312

By:

Sun, Fei;
Wang, Pengcheng;
Zheng, Yiming;
Jia, Weiguang;
Liu, Fuxing;
Xiao, Wei;
Bao, Jingjing;
Wang, Song;
Lu, Kaijin

Publication type:

Article

PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling.

Published in:

Oncogene, 2014, v. 33, n. 46, p. 5348, doi. 10.1038/onc.2013.477

By:

Zhu, B;
Ferry, C H;
Blazanin, N;
Bility, M T;
Khozoie, C;
Kang, B-H;
Glick, A B;
Gonzalez, F J;
Peters, J M

Publication type:

Article

Comprehensive profiling of H-Ras signalling in angiosarcoma endothelium.

Published in:

Clinical & Experimental Dermatology, 2017, v. 42, n. 6, p. 645, doi. 10.1111/ced.13149

By:

Costa, A.;
Bonner, M.;
Arbiser, J. L.

Publication type:

Article

Codeletion of the JUN proto-oncogene and the CDKN2A tumor-suppressor gene in HRAS-transformed rat embryo fibroblast cell lines.

Published in:

Genes, Chromosomes & Cancer, 1997, v. 20, n. 1, p. 82, doi. 10.1002/(SICI)1098-2264(199709)20:1<82::AID-GCC12>3.0.CO;2-H

By:

Zhou, Jian-Nian;
Ljungdahl, Sofia;
Röhme, Dan;
Levan, Göran;
Shoshan, Maria C.;
Linder, Stig

Publication type:

Article

Mechanism of the Exchange Reaction in HRAS from Multiscale Modeling.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0108846

By:

Kapoor, Abhijeet;
Travesset, Alex

Publication type:

Article

Early-Lethal Costello Syndrome Due to Rare HRAS Tandem Base Substitution (c.35_36GC>AA; p.G12E)-Associated Pulmonary Vascular Disease.

Published in:

Pediatric & Developmental Pathology, 2014, v. 17, n. 6, p. 421, doi. 10.2350/14-05-1488-OA.1

By:

WEAVER, K. NICOLE;
WANG, DEHUA;
CNOTA, JAMES;
GARDNER, NICHOLAS;
STABLEY, DEBORAH;
SOL-CHURCH, KATIA;
GRIPP, KAREN W.;
WITTE, DAVID P.;
BOVE, KEVIN E.;
HOPKIN, ROBERT J.

Publication type:

Article

The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype–Phenotype Study.

Published in:

Cancers, 2020, v. 12, n. 2, p. 283, doi. 10.3390/cancers12020283

By:

AL-Eitan, Laith N.;
Al-Ahmad, Bashar H.;
Almomani, Fouad A.

Publication type:

Article

Meet me in the cytoplasm: A role for p27 in the control of H-Ras.

Published in:

2016

By:

Baldassarre, Gustavo;
Belletti, Barbara

Publication type:

Opinion

Absence of BRAF, NRAS, KRAS, HRAS Mutations, and RET/ PTC Gene Rearrangements Distinguishes Dominant Nodules in Hashimoto Thyroiditis from Papillary Thyroid Carcinomas.

Published in:

Endocrine Pathology, 2010, v. 21, n. 2, p. 73, doi. 10.1007/s12022-009-9101-3

By:

Sadow, Peter;
Heinrich, Michael;
Corless, Christopher;
Fletcher, Jonathan;
Nosé, Vânia

Publication type:

Article

Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines.

Published in:

Odontology, 2012, v. 100, n. 2, p. 149, doi. 10.1007/s10266-011-0032-3

By:

Maemoto, Sachiko;
Yumoto, Megumi;
Ibata, Masato;
Torizuka, Sho;
Ozawa, Naohumi;
Tatsumi, Shunsuke;
Hashido, Moeko;
Morikawa, Masako;
Maeda, Genta;
Imai, Kazushi

Publication type:

Article

RTK/RAS Can't Do it Alone in Causing Bladder Cancer.

Published in:

AUANews, 2015, v. 20, n. 11, p. 17

By:

Xue-Ru Wu

Publication type:

Article

Dysregulation of astrocyte extracellular signaling in Costello syndrome.

Published in:

Science Translational Medicine, 2015, v. 7, n. 286, p. 1, doi. 10.1126/scitranslmed.aaa5645

By:

Krencik, Robert;
Hokanson, Kenton C.;
Narayan, Aditi R.;
Dvornik, Jill;
Rooney, Gemma E.;
Rauen, Katherine A.;
Weiss, Lauren A.;
Rowitch, David H.;
Ullian, Erik M.

Publication type:

Article

Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140253

By:

Weyandt, Jamie D.;
Lampson, Benjamin L.;
Tang, Sherry;
Mastrodomenico, Matthew;
Cardona, Diana M.;
Counter, Christopher M.

Publication type:

Article

BRAF, HRAS, KRAS, NRAS and CDKN2A genes analysis in cultured melanocytes used for vitiligo treatment.

Published in:

International Journal of Dermatology, 2011, v. 50, n. 2, p. 180, doi. 10.1111/j.1365-4632.2010.04675.x

By:

Czajkowski, Rafal

Publication type:

Article

Mammary Epithelial-Myoepithelial Carcinoma: Report of a Case With HRAS and PIK3CA Mutations by Next-Generation Sequencing.

Published in:

2019

By:

Baum, Jordan E.;
Kap-Jae Sung;
Hung Tran;
Wei Song;
Ginter, Paula S.

Publication type:

Case Study

Epithelial-Myoepithelial Carcinoma of the Salivary Gland Harboring HRAS Codon 61 Mutations With Lung Metastasis.

Published in:

2016

By:

Hsieh, Min-Shu;
Chen, Jin-Shing;
Lee, Yi-Hsuan;
Chou, Yueh-Hung

Publication type:

Case Study

Phacomatosis pigmentokeratotica: a case of HRAS mosaicism causing rhabdomyosarcoma.

Published in:

2018

By:

Prieto‐Barrios, M.;
Llamas‐Martin, R.;
Velasco‐Tamariz, V.;
Calleja‐Algarra, A.;
Ruano, Y.;
Ortiz‐Romero, P.L.;
Rodriguez‐Peralto, J.L.

Publication type:

Case Study

Mosaic pathogenic <italic>HRAS</italic> variant in a patient with nevus spilus with agminated Spitz nevi and parametrial–uterine rhabdomyosarcoma.

Published in:

2018

By:

Nemeth, K.;
Szabo, S.;
Cottrell, C. E.;
McNulty, S. M.;
Segura, A.;
Sokumbi, O.;
Browning, M.;
Siegel, D. H.

Publication type:

Case Study

Phacomatosis pigmentokeratotica and precocious puberty associated with <italic>HRAS</italic> mutation.

Published in:

2018

By:

Martin, R. J.;
Arefi, M.;
Splitt, M.;
Redford, L.;
Moss, C.;
Rajan, N.

Publication type:

Case Study

Comparative analysis of the NF2, TP53, PTEN, KRAS, NRAS and HRAS genes in sporadic and radiation-induced human meningiomas.

Published in:

International Journal of Cancer, 2001, v. 94, n. 2, p. 218, doi. 10.1002/ijc.1467

By:

Joachim, Thomas;
Ram, Zvi;
Rappaport, Zvi H.;
Simon, Matthias;
Schramm, Johannes;
Wiestler, Otmar D.;
von Deimling, Andreas

Publication type:

Article

The HRASLS (PLA/AT) subfamily of enzymes.

Published in:

Journal of Biomedical Science, 2015, v. 22, p. 1, doi. 10.1186/s12929-015-0210-7

By:

Mardian, Emily B.;
Bradley, Ryan M.;
Duncan, Robin E.

Publication type:

Article

Treatment of consistent BRAF/HRAS gene mutation and MYC amplification radiation-induced abdominal wall angiosarcoma with low-dose apatinib: a case report.

Published in:

2019

By:

Guan, Jieshan;
Luo, Zhijie;
Xiao, Zhiwei;
Xie, Yubin;
Lin, Lizhu

Publication type:

journal article

Costello syndrome: clinical diagnosis in the first year of life.

Published in:

2008

By:

Digilio, M. Cristina;
Sarkozy, Anna;
Capolino, Rossella;
Testa, M. Beatrice Chiarini;
Esposito, Giorgia;
De Zorzi, Andrea;
Cutrera, Renato;
Marino, Bruno;
Dallapiccola, Bruno;
Chiarini Testa, M Beatrice

Publication type:

journal article

Association of Schimmelpenning Syndrome with Astrocytoma (WHO Grade 3): Case Report.

Published in:

Medicina (1010660X), 2024, v. 60, n. 10, p. 1688, doi. 10.3390/medicina60101688

By:

Tumova, Aija;
Auslands, Kaspars;
Millers, Andrejs;
Priede, Zanda;
Buks, Māris;
Ozola, Agnese;
Ozoliņa, Elīna;
Bicāns, Kārlis;
Ulmanis, Rūdolfs

Publication type:

Article

Syndrome de Costello: à propos d'une observation.

Published in:

Pan African Medical Journal, 2012, v. 12, p. 1

By:

Tajir, Mariam;
Fergelot, Patricia;
Lancelot, Gwenaelle;
Arveiler, Benoit;
Elalaoui, Siham Chafai;
Lacombe, Didier;
Sefiani, Abdelaziz

Publication type:

Article

Epithelial–myoepithelial carcinoma ex-pleomorphic adenoma of the parotid gland: report of a rare case with immunohistochemical and genetic analyses.

Published in:

Medical Molecular Morphology, 2021, v. 54, n. 2, p. 173, doi. 10.1007/s00795-020-00262-6

By:

Kusafuka, Kimihide;
Yamashita, Masaru;
Muramatsu, Aya;
Arai, Kazumori;
Suzuki, Makoto

Publication type:

Article

Fatal leukodystrophy in Costello syndrome: a case report.

Published in:

2023

By:

Failoc-Rojas, Virgilio E.;
Ugaz, Piero A. Quiroz;
León, Dante A. Loconi;
Zeña-Ñañez, Sandra

Publication type:

Case Study

Progressively worsening hypertrophic cardiomyopathy in a child with newly diagnosed Costello syndrome while receiving growth hormone therapy.

Published in:

Cardiology in the Young, 2010, v. 20, n. 4, p. 459, doi. 10.1017/S1047951110000260

By:

Kobayashi, Daisuke;
Cook, Amanda L.;
Williams, Derek A.

Publication type:

Article

Recombinant growth hormone therapy in a girl with costello syndrome: a 4-year observation.

Published in:

Italian Journal of Pediatrics, 2016, v. 42, p. 1, doi. 10.1186/s13052-015-0209-4

By:

Blachowska, Ewa;
Petriczko, Elżbieta;
Horodnicka-Józwa, Anita;
Skórka, Agata;
Pelc, Magdalena;
Krajewska-Walasek, Małgorzata;
Walczak, Mieczysław

Publication type:

Article

Does Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features (NIFTP) Have a Unique Molecular Profile?

Published in:

2018

By:

Brandler, Tamar C;
Liu, Cheng Z;
Cho, Margaret;
Zhou, Fang;
Cangiarella, Joan;
Yee-Chang, Melissa;
Shi, Yan;
Simsir, Aylin;
Sun, Wei

Publication type:

journal article

Mechanisms of HRAS regulation of liver hepatocellular carcinoma for prognosis prediction.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14131-x

By:

Fang, Xingbao;
Cai, Yan;
Zhao, Zhuoyu;
Yang, Shaohua;
Li, Zhaojun;
Peng, Xiongbing;
Hang, Meifang;
Liu, Peiwan;
Li, Yuehong

Publication type:

Article

Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma.

Published in:

Oncology Letters, 2014, v. 8, n. 3, p. 1249, doi. 10.3892/ol.2014.2253

By:

WENMIN HOU;
JIBIN LIU;
PEIZHAN CHEN;
HUI WANG;
BANG-CE YE;
FULIN QIANG

Publication type:

Article

Variations in MAP kinase gladiators and risk of differentiated thyroid carcinoma.

Published in:

Molecular & Clinical Oncology, 2022, v. 16, n. 2, p. 1, doi. 10.3892/mco.2021.2478

By:

RASHID, FAIZA A.;
BHAT, GHULAM HASSAN;
KHAN, MOSIN S.;
TABASSUM, SOBIA;
BHAT, MOHAMMAD HAYAT

Publication type:

Article

Molecular Characterization, Compositional Analysis, and Germination Evaluation of a High-Oleic Soybean Generated by the Suppression of FAD2-1 Expression.

Published in:

Crop Science, 2014, v. 54, n. 5, p. 2160, doi. 10.2135/cropsci2012.06.0377

By:

Brink, Kent;
Chok-Fun Chui Jr.;
Cressman, Robert F.;
Garcia, Patrick;
Henderson, Nancy;
Bonnie Hong;
Maxwell, Carl A.;
Meyer, Knut;
Mickelson, James;
Stecca, Kevin L.;
Tyree, Cheri W.;
Weber, Natalie;
Weiqing Zeng;
Zhong, Cathy X.

Publication type:

Article

Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome.

Published in:

Nature Genetics, 2012, v. 44, n. 7, p. 783, doi. 10.1038/ng.2316

By:

Groesser, Leopold;
Herschberger, Eva;
Ruetten, Arno;
Ruivenkamp, Claudia;
Lopriore, Enrico;
Zutt, Markus;
Langmann, Thomas;
Singer, Sebastian;
Klingseisen, Laura;
Schneider-Brachert, Wulf;
Toll, Agusti;
Real, Francisco X;
Landthaler, Michael;
Hafner, Christian

Publication type:

Article

Gene expression phenotypic models that predict the activity of oncogenic pathways.

Published in:

Nature Genetics, 2003, v. 34, n. 2, p. 226, doi. 10.1038/ng1167

By:

Huang, Erich;
Ishida, Seiichi;
Pittman, Jennifer;
Dressman, Holly;
Bild, Andrea;
Kloos, Mark;
D'Amico, Mark;
Pestell, Richard G;
West, Mike;
Nevins, Joseph R

Publication type:

Article

Mutation analysis of the genes involved in the Ras-mitogen-activated protein kinase (MAPK) pathway in Korean patients with Noonan syndrome.

Published in:

Clinical Genetics, 2007, v. 72, n. 2, p. 150, doi. 10.1111/j.1399-0004.2007.00839.x

By:

Lee, S.-T.;
Ki, C.-S.;
Lee, H. J.

Publication type:

Article

Genetic mutations and prognostic indicators in differentiated thyroid cancer: a molecular perspective.

Published in:

Turkish Journal of Medical Sciences, 2025, v. 55, n. 1, p. 72, doi. 10.55730/1300-0144.5944

By:

ÖZÇEVİK, Halim;
ÖNER TAMAM, Müge;
BABACAN, Gündüzalp Buğrahan;
ŞENGİZ ERHAN, Selma;
ACAR TAYYAR, Merve Nur;
ERTÜRK, Biray

Publication type:

Article

Costello syndrome with special cutaneous manifestations and HRAS G12D mutation: A case report and literature review.

Published in:

Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 6, p. 1, doi. 10.1002/mgg3.1690

By:

Qian, Wen;
Zhang, Meijie;
Huang, Hequn;
Chen, Yihe;
Park, Gajin;
Zeng, Ni;
Li, Yueyue;
Lu, Qian;
Luo, Dan

Publication type:

Article