Works matching H. Robert Horvitz

Results: 85

The Bristol-Myers Squibb Award for Distinguished Achievement in Neuroscience Research, 2001: H. Robert Horvitz, PhD.

Published in:: Neuroscientist, 2001, v. 7, n. 6, p. 551, doi. 10.1177/107385840100700611
Publication type:: Article

ВІДКРИТТЯ ГЕНІВ РЕГУЛЯЦІЇ АПОПТОЗУ КЛІТИН: СІДНІ БРЕННЕР, ДЖОН САЛСТОН ТА РОБЕРТ ГОРВІЦ (НОБЕЛІВСЬКА ПРЕМІЯ З ФІЗІОЛОГІЇ ТА МЕДИЦИНИ, 2002 Р.)

Published in:

Ukrainian Biochemical Journal, 2021, v. 93, n. 3, p. 111, doi. 10.15407/ubj93.03.111

By:

ГРИГОР'ЄВА, М. В.;
ДАНИЛОВА, В. М.;
КОМІСАРЄНКО, С. В.

Publication type:

Article

A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans.

Published in:

Nature, 1987, v. 326, n. 6110, p. 259, doi. 10.1038/326259a0

By:

Ferguson, Edwin L.;
Sternberg, Paul W.;
Horvitz, H. Robert

Publication type:

Article

The transcriptional corepressor CTBP-1 acts with the SOX family transcription factor EGL-13 to maintain AIA interneuron cell identity in Caenorhabditis elegans.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.74557

By:

Saul, Josh;
Takashi Hirose;
Horvitz, H. Robert

Publication type:

Article

An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.59341

By:

Sando, Steven R.;
Bhatla, Nikhil;
Lee, Eugene L. Q.;
Horvitz, H. Robert

Publication type:

Article

Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038649

By:

Omura, Daniel T.;
Clark, Damon A.;
Samuel, Aravinthan D. T.;
Robert Horvitz, H.

Publication type:

Article

sup-9, sup-10, and unc-93 May Encode Components of a Two-Pore K[sup+] Channel that Coordinates Muscle Contraction in Caenorhabditis elegans.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 27, p. 9133, doi. 10.1523/JNEUROSCI.23-27-09133.2003

By:

de la Cruz, Ignacio Perez;
Levin, Joshua Z.;
Cummins, Claudia;
Anderson, Philip;
Horvitz, H. Robert

Publication type:

Article

IRK-1 Potassium Channels Mediate Peptidergic Inhibition of Caenorhabditis elegans Serotonin Neurons via a G<sub>o</sub> Signaling Pathway.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 46, p. 16285, doi. 10.1523/JNEUROSCI.2667-12.2012

By:

Emtage, Lesley;
Aziz-Zaman, Sonya;
Padovan-Merhar, Olivia;
Horvitz, H. Robert;
Fang-Yen, Christopher;
Ringstad, Niels

Publication type:

Article

Deletion of VPS50 protein in mouse brain impairs synaptic function and behavior.

Published in:

BMC Biology, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12915-024-01940-y

By:

Ahumada-Marchant, Constanza;
Ancatén-Gonzalez, Carlos;
Haensgen, Henny;
Brauer, Bastian;
Merino-Veliz, Nicolas;
Droste, Rita;
Arancibia, Felipe;
Horvitz, H. Robert;
Constantine-Paton, Martha;
Arriagada, Gloria;
Chávez, Andrés E.;
Bustos, Fernando J.

Publication type:

Article

Receptors and Other Signaling Proteins Required for Serotonin Control of Locomotion in Caenorhabditis elegans.

Published in:

Genetics, 2012, v. 192, n. 4, p. 1359, doi. 10.1534/genetics.112.142125

By:

Güre, Güliz;
Gustafson, Megan A.;
Pepper, Judy S.;
Horvitz, H. Robert;
Koelle, Michael R.

Publication type:

Article

The LIN-15A and LIN-56 Transcriptional Regulators Interact to Negatively Regulate EGF/Ras Signaling in Caenorhabditis elegans Vulval Cell-Fate Determination.

Published in:

Genetics, 2011, v. 187, n. 3, p. 803, doi. 10.1534/genetics.110.124487

By:

Davison, Ewa M.;
Saffer, Adam M.;
Huang, Linda S.;
DeModena, John;
Sternberg, Paul W.;
Horvitz, H. Robert

Publication type:

Article

Multiple Levels of Redundant Processes Inhibit Caenorhabditis elegans Vulval Cell Fates.

Published in:

Genetics, 2008, v. 179, n. 4, p. 2001, doi. 10.1534/genetics.108.092197

By:

Andersen, Erik C.;
Saffer, Adam M.;
Horvitz, H. Robert

Publication type:

Article

Caenorhabditis elegans Genes Required for the Engulfment of Apoptotic Corpses Function in the Cytotoxic Cell Deaths Induced by Mutations in lin-24 and lin-33.

Published in:

Genetics, 2008, v. 179, n. 1, p. 403, doi. 10.1534/genetics.108.087221

By:

Galvin, Brendan D.;
Kim, Saechin;
Horvitz, H. Robert

Publication type:

Article

LIN-61, One of Two Caenorhabditis elegans Malignant-Brain-Tumor-Repeat-Containing Proteins, Acts With the DRM and NuRD-Like Protein Complexes in Vulval Development but Not in Certain Other Biological Processes.

Published in:

Genetics, 2007, v. 176, n. 1, p. 255, doi. 10.1534/genetics.106.069633

By:

Harrison, Melissa M.;
Xiaowei Lu;
Horvitz, H. Robert

Publication type:

Article

DPL-1 DP, LIN-35 Rb and EFL-1 E2F Act With the MCD-1 Zinc-Finger Protein to Promote Programmed Cell Death in Caenorhabditis elegans.

Published in:

Genetics, 2007, v. 175, n. 4, p. 1719, doi. 10.1534/genetics.106.068148

By:

Reddien, Peter W.;
Andersen, Erik C.;
Huang, Michael C.;
Horvitz, H. Robert

Publication type:

Article

Identification and Classification of Genes That Act Antagonistically to let-60 Ras Signaling in Caenorhabditis elegans Vulval Development.

Published in:

Genetics, 2006, v. 173, n. 2, p. 709, doi. 10.1534/genetics.106.056465

By:

Ceo, Craig J.;
Stegmeier, Frank;
Harrison, Melissa M.;
Horvitz, H. Robert

Publication type:

Article

Lin-8, Which Antagonizes Caenorhabditis elegans Ras-Mediated Vulval Induction, Encodes a Novel Nuclear Protein That Interacts With the LIN-35 Rb Protein.

Published in:

Genetics, 2005, v. 171, n. 3, p. 1017, doi. 10.1534/genetics.104.034173

By:

Ewa M. Davison;
Melissa M. Harrison;
Albertha J. M. Walhout;
Marc Vidal;
Horvitz, H. Robert

Publication type:

Article

New Genes That Interact With lin-35 Rb to Negatively Regulate the let-60 ras Pathway in Caenorhabditis elegans.

Published in:

Genetics, 2003, v. 164, n. 1, p. 135, doi. 10.1093/genetics/164.1.135

By:

Thomas, Jeffrey H.;
Ceol, Craig J.;
Schwartz, Hillel T.;
Horvitz, H. Robert

Publication type:

Article

FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans.

Published in:

Nature Neuroscience, 2008, v. 11, n. 10, p. 1168, doi. 10.1038/nn.2186

By:

Ringstad, Niels;
Horvitz, H. Robert

Publication type:

Article

Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07640-w

By:

Burton, Nicholas O.;
Dwivedi, Vivek K.;
Burkhart, Kirk B.;
Kaplan, Rebecca E. W.;
Baugh, L. Ryan;
Horvitz, H. Robert

Publication type:

Article

Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 1998, v. 43, n. 5, p. 645, doi. 10.1002/ana.410430514

By:

Aoki, Masashi;
Lin, Chien-Liang G.;
Rothstein, Jeffrey D.;
Geller, Brian A.;
Hosler, Besty A.;
Munsat, Theodore L.;
Horvitz, H. Robert;
Brown, Robert H.

Publication type:

Article

The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans.

Published in:

Journal of Biology, 2006, v. 5, p. 1

By:

Cheng-Wen Su;
Tharin, Suzanne;
Yishi Jin;
Wightman, Bruce;
Spector, Mona;
Meili, David;
Tsung, Nancy;
Rhiner, Christa;
Bourikas, Dimitris;
Stoeckli, Esther;
Garriga, Gian;
Horvitz, H. Robert;
Hengartner, Michael O.

Publication type:

Article

A Neuronal Acetylcholine Receptor Regulates the Balance of Muscle Excitation and Inhibition in Caenorhabditis elegans.

Published in:

PLoS Biology, 2009, v. 7, n. 12, p. 1, doi. 10.1371/journal.pbio.1000265

By:

Jospin, Maelle;
Yingchuan B. Qi;
Stawicki, Tamara M.;
Boulin, Thomas;
Schuske, Kim R.;
Horvitz, H. Robert;
Bessereau, Jean-Louis;
Jorgensen, Erik M.;
Yishi Jin

Publication type:

Article

Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans.

Published in:

PLoS Biology, 2009, v. 7, n. 4, p. 0876, doi. 10.1371/journal.pbio.1000099

By:

Hurwitz, Michael E.;
Vanderzalm, Pamela J.;
Bloom, Laird;
Goldman, Julia;
Garriga, Gian;
Horvitz, H. Robert

Publication type:

Article

Worms, Life, and Death (Nobel Lecture) ( Copyright © The Nobel Foundation, 2003. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.).

Published in:

ChemBioChem, 2003, v. 4, n. 8, p. 697, doi. 10.1002/cbic.200300614

By:

H. Robert Horvitz

Publication type:

Article

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180.

Published in:

Nature, 1998, v. 392, n. 6675, p. 501, doi. 10.1038/33163

By:

Wu, Yi-Chun;
Horvitz, H. Robert

Publication type:

Article

Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor.

Published in:

Nature, 1997, v. 390, n. 6657, p. 305, doi. 10.1038/36889

By:

Xue, Ding;
Horvitz, H. Robert

Publication type:

Article

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in ...

Published in:

Nature, 1995, v. 377, n. 6546, p. 248, doi. 10.1038/377248a0

By:

Xue, Ding;
Horvitz, H. Robert

Publication type:

Article

Activation of `C.elegans' cell death protein CED-9 by an amino-acid substitution in a domain...

Published in:

Nature, 1994, v. 369, n. 6478, p. 318, doi. 10.1038/369318a0

By:

Hengartner, Michael O.;
Horvitz, H. Robert

Publication type:

Article

Mutations in the a1 subunit of an L-type voltage-activated Ca<sup>2+</sup> channel cause myotonia in Caenorhabditis elegans.

Published in:

EMBO Journal, 1997, v. 16, n. 20, p. 6066, doi. 10.1093/emboj/16.20.6066

By:

Lee, Raymond Y. N.;
Lobel, Leslie;
Hengartner, Michael;
Horvitz, H. Robert;
Avery, Leon

Publication type:

Article

Superoxide Dismutase Concentration and Activity in Familial Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neurochemistry, 1995, v. 64, n. 5, p. 2366, doi. 10.1046/j.1471-4159.1995.64052366.x

By:

Bowling, Allen C.;
Barkowski, Elizabeth E.;
McKenna-Yasek, D.;
Sapp, Peter;
Horvitz, H. Robert;
Beal, M. Flint;
Brown, Robert H.

Publication type:

Article

Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22.

Published in:

2000

By:

Hosler, Betsy A.;
Siddique, Teepu;
Sapp, Peter C.;
Sailor, Wen;
Huang, Michael C.;
Hossain, Anwar;
Daube, Jasper R.;
Nance, Martha;
Fan, Chaohong;
Kaplan, Jocelyn;
Hung, Wu-Yen;
McKenna-Yasek, Diane;
Haines, Jonathan L.;
Pericak-Vance, Margaret A.;
Horvitz, H. Robert;
Brown Jr., Robert H.;
Hosler, B A;
Siddique, T;
Sapp, P C;
Sailor, W

Publication type:

journal article

Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans.

Published in:

BMC Biology, 2016, v. 14, p. 1, doi. 10.1186/s12915-016-0262-5

By:

Johnsen, Holly L.;
Horvitz, H. Robert

Publication type:

Article

A C. elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility.

Published in:

PLoS Genetics, 2018, v. 14, n. 4, p. 1, doi. 10.1371/journal.pgen.1007295

By:

Engert, Christoph G.;
Droste, Rita;
van Oudenaarden, Alexander;
Horvitz, H. Robert

Publication type:

Article

Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis.

Published in:

Nature, 2003, v. 423, n. 6938, p. 439, doi. 10.1038/nature01634

By:

Hwang, Ho-Yon;
Olson, Sara K.;
Esko, Jeffrey D.;
Robert Horvitz, H.

Publication type:

Article

Phagocytosis promotes programmed cell death in C. elegans.

Published in:

Nature, 2001, v. 412, n. 6843, p. 198, doi. 10.1038/35084096

By:

Reddien, Peter W.;
Cameron, Scott;
Horvitz, H. Robert

Publication type:

Article

MOD-1 is a seratonin-gated chloride channel that modulates locomotory behaviour in C. elegans.

Published in:

Nature, 2000, v. 408, n. 6811, p. 470, doi. 10.1038/35044083

By:

Rangathan, Rajesh;
Cannon, Stephen C.;
Horvitz, H. Robert

Publication type:

Article

MicroRNA expression profiles classify human cancers.

Published in:

Nature, 2005, v. 435, n. 7043, p. 834, doi. 10.1038/nature03702

By:

Lu, Jun;
Getz, Gad;
Miska, Eric A.;
Alvarez-Saavedra, Ezequiel;
Lamb, Justin;
Peck, David;
Sweet-Cordero, Alejandro;
Ebert, Benjamin L.;
Mak, Raymond H.;
Ferrando, Adolfo A.;
Downing, James R.;
Jacks, Tyler;
Horvitz, H. Robert;
Golub, Todd R.

Publication type:

Article

Obituary: Stanley J. Korsmeyer (1950-2005).

Published in:

2005

By:

Horvitz, H. Robert

Publication type:

Obituary

Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal...

Published in:

Genetics, 1998, v. 149, n. 4, p. 1809, doi. 10.1093/genetics/149.4.1809

By:

Jacobs, Dave;
Beitel, Greg J.;
Clark, Scott G.;
Horvitz, H. Robert;
Kornfeld, Kerry

Publication type:

Article

Three new classes of mutations in the Caenorhabditis elegans muscle gene sup-9.

Published in:

Genetics, 1993, v. 135, n. 1, p. 53, doi. 10.1093/genetics/135.1.53

By:

Levin, Joshua Z.;
Horvitz, H. Robert

Publication type:

Article

The Caenorhabditis elegans unc-31 Gene Affects Multiple Nervous System-Controlled Functions.

Published in:

Genetics, 1993, v. 134, n. 2, p. 455

By:

Avery, Leon;
Bargmann, Cornelia I.;
Horvitz, H. Robert

Publication type:

Article

Genes Required for the Engulfment of Cell Corpses During Programmed Cell Death in Caenorhabditis elegans.

Published in:

Genetics, 1991, v. 129, n. 1, p. 79, doi. 10.1093/genetics/129.1.79

By:

Ellis, Ronald E.;
Jacobson, Dean M.;
Horvitz, H. Robert

Publication type:

Article

"Joy of the Worm".

Published in:

Genetics, 1990, v. 126, n. 2, p. 287

By:

Horvitz, H. Robert;
Sulston, John E.

Publication type:

Article

The Multivulva Phenotype of Certain Caenorhabditis elegans Mutants Results From Defects in Two Functionally Redundant Pathways.

Published in:

Genetics, 1989, v. 123, n. 1, p. 109

By:

Ferguson, Edwin L.;
Horvitz, H. Robert

Publication type:

Article

Caenorhabditis elegans Mutants Defective in the Functioning of the Motor Neurons Responsible for Egg Laying.

Published in:

Genetics, 1989, v. 121, n. 4, p. 703

By:

Desai, Chand;
Horvitz, H. Robert

Publication type:

Article

Molecular Genetics of the Caenorhabditis elegans Heterochronic Gene lin-14.

Published in:

Genetics, 1989, v. 121, n. 3, p. 501

By:

Ruvkun, Gary;
Ambros, Victor;
Coulson, Alan;
Waterston, Robert;
Sulston, John;
Horvitz, H. Robert

Publication type:

Article

A Novel Dominant Transformer Allele of the Sex-Determining Gene her-1 of Caenorhabditis elegans.

Published in:

Genetics, 1988, v. 120, n. 1, p. 145

By:

Trent, Carol;
Wood, William B.;
Horvitz, H. Robert

Publication type:

Article

C. ELEGANS UNC-105 MUTATIONS AFFECT MUSCLE AND ARE SUPPRESSED BY OTHER MUTATIONS THAT AFFECT MUSCLE.

Published in:

Genetics, 1986, v. 113, n. 4, p. 853

By:

EUN-CHUNG PARK;
HORVITZ, H. ROBERT

Publication type:

Article

MUTATIONS WITH DOMINANT EFFECTS ON THE BEHAVIOR AND MORPHOLOGY OF THE NEMATODE CAENORHABDITIS ELEGANS.

Published in:

Genetics, 1986, v. 113, n. 4, p. 821

By:

EUN-CHUNG PARK;
HORVITZ, H. ROBERT

Publication type:

Article