Works matching Glucokinase
Results: 2470
Glucokinase and Glucokinase Regulatory Proteins are Functionally Coexpressed before Birth in the Rat Brain.
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- Journal of Neuroendocrinology, 2009, v. 21, n. 12, p. 973, doi. 10.1111/j.1365-2826.2009.01919.x
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- Article
Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain.
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- Journal of Neurochemistry, 2002, v. 80, n. 1, p. 45, doi. 10.1046/j.0022-3042.2001.00677.x
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- Article
Role of Glucokinase in the Subcellular Localization of Glucokinase Regulatory Protein.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 4, p. 7377, doi. 10.3390/ijms16047377
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Glucokinase and glucokinase regulatory proteins as molecular targets for novel antidiabetic drugs.
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- Molecular Biology, 2015, v. 49, n. 4, p. 494, doi. 10.1134/S0026893315040147
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- Article
Present status of clinical deployment of glucokinase activators.
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- Journal of Diabetes Investigation, 2015, v. 6, n. 2, p. 124, doi. 10.1111/jdi.12294
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Evaluating the impact of glucokinase activation on risk of cardiovascular disease: a Mendelian randomisation analysis.
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- Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01613-6
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- Article
Regulation of liver glucokinase activity in rats with fructose-induced insulin resistance and impaired glucose and lipid metabolism.
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- Canadian Journal of Physiology & Pharmacology, 2009, v. 87, n. 9, p. 702, doi. 10.1139/Y09-064
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- Article
Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians M. Veiga-da-Cunha et al.: Mutation in glucokinase regulatory protein.
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- Diabetologia, 2003, v. 46, n. 5, p. 704, doi. 10.1007/s00125-003-1083-y
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- Article
Liver glucokinase gene expression is controlled by the onecut transcription factor hepatocyte nuclear factor-6 V.J. Lannoy et al.: Hepatocyte nuclear factor-6 and glucokinase.
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- Diabetologia, 2002, v. 45, n. 8, p. 1136, doi. 10.1007/s00125-002-0856-z
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- Article
Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activation.
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- Diabetes, Obesity & Metabolism, 2012, v. 14, p. 109, doi. 10.1111/j.1463-1326.2012.01652.x
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- Article
Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice.
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- Diabetes, Obesity & Metabolism, 2008, v. 10, n. 10, p. 885, doi. 10.1111/j.1463-1326.2007.00819.x
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- Article
NOVEL MULTI ACTION THERAPY APPROACHES OF GLUCOKINASE ACTIVATOR TO TREAT TYPE 2 DIABETES.
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- Journal of Advanced Scientific Research, 2020, v. 11, n. 3, p. 62
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- Article
In silico design of dehydrophenylalanine containing peptide activators of glucokinase using pharmacophore modelling, molecular dynamics and machine learning: implications in type 2 diabetes.
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- Journal of Computer-Aided Molecular Design, 2024, v. 39, n. 1, p. 1, doi. 10.1007/s10822-024-00583-z
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- Article
ATP- and Polyphosphate-Dependent Glucokinases from Aerobic Methanotrophs.
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- Microorganisms, 2019, v. 7, n. 2, p. 52, doi. 10.3390/microorganisms7020052
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A comprehensive review on glucokinase activators: Promising agents for the treatment of Type 2 diabetes.
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- 2022
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- Literature Review
Efficacy and safety of glucokinase activators for type 2 diabetes mellitus therapy: a meta-analysis of double-blind randomized controlled trials.
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- European Review for Medical & Pharmacological Sciences, 2021, v. 25, n. 2, p. 914
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Glucokinase regulatory protein is associated with mitochondria in hepatocytes
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- FEBS Letters, 2006, v. 580, n. 8, p. 2065, doi. 10.1016/j.febslet.2006.03.009
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QSAR Models Guided by Molecular Dynamics Applied to Human Glucokinase Activators.
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- Chemical Biology & Drug Design, 2016, v. 87, n. 3, p. 455, doi. 10.1111/cbdd.12683
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Effect of GRP119 Receptor Agonist, Compound MBX-2982, on Activity of Human Glucokinase.
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- Bulletin of Experimental Biology & Medicine, 2017, v. 163, n. 5, p. 695, doi. 10.1007/s10517-017-3881-0
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Comparative Structural and Functional Analysis of Staphylococcus aureus Glucokinase with other Bacterial Glucokinases.
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- Indian Journal of Pharmaceutical Sciences, 2014, v. 76, n. 5, p. 430
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Specificity evolution of the ADP-dependent sugar kinase family – in silico studies of the glucokinase/phosphofructokinase bifunctional enzyme from Methanocaldococcus jannaschii.
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- FEBS Journal, 2008, v. 275, n. 16, p. 4033, doi. 10.1111/j.1742-4658.2008.06544.x
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The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism.
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- FEBS Journal, 2006, v. 273, n. 2, p. 336, doi. 10.1111/j.1742-4658.2005.05067.x
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- Article
Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats.
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- British Journal of Pharmacology, 2006, v. 149, n. 3, p. 328, doi. 10.1038/sj.bjp.0706848
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- Article
Glucokinase regulatory protein: a balancing act between glucose and lipid metabolism in NAFLD.
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- Frontiers in Endocrinology, 2023, p. 01, doi. 10.3389/fendo.2023.1247611
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- Article
Ischemic preconditioning maintains the immunoreactivities of glucokinase and glucokinase regulatory protein in neurons of the gerbil hippocampal CA1 region following transient cerebral ischemia.
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- Molecular Medicine Reports, 2015, v. 12, n. 4, p. 4939, doi. 10.3892/mmr.2015.4021
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- Article
β‐Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control.
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- Journal of Diabetes, 2023, v. 15, n. 5, p. 409, doi. 10.1111/1753-0407.13380
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- Article
Characterization of Polyphosphate Glucokinase SC05059 from Streptomyces coelicolor A3(2).
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- Bioscience, Biotechnology & Biochemistry, 2013, v. 77, n. 11, p. 2322, doi. 10.1271/bbb.130498
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- Article
Tetrahydropalmatine from medicinal plants activates human glucokinase to regulate glucose homeostasis.
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- Biotechnology & Applied Biochemistry, 2024, v. 71, n. 2, p. 295, doi. 10.1002/bab.2541
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- Article
Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 606, doi. 10.1080/14756366.2021.2025362
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- Article
Clinical characteristics of mutation carriers in a large family with glucokinase diabetes (MODY2).
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- Diabetic Medicine, 2005, v. 22, n. 8, p. 994, doi. 10.1111/j.1464-5491.2005.01555.x
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- Article
Hexokinase and Glucokinases Are Essential for Fitness and Virulence in the Pathogenic Yeast Candida albicans.
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- Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.00327
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- Article
Sapium ellipticum (Hochst) Pax ethanol leaf extract modulates glucokinase and glucose-6-phosphatase activities in streptozotocin induced diabetic rats.
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- Asian Pacific Journal of Tropical Biomedicine, 2017, v. 7, n. 6, p. 544, doi. 10.1016/j.apjtb.2017.05.009
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- Article
Evaluation of efficacy and safety of glucokinase activators--a systematic review and meta-analysis.
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- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1175198
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- Article
Effects of glucokinase haploinsufficiency on the pancreatic β‐cell mass and function of long‐term high‐fat, high‐sucrose diet‐fed mice.
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- Journal of Diabetes Investigation, 2024, v. 15, n. 12, p. 1732, doi. 10.1111/jdi.14307
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- Article
Glucokinase is required for high‐starch diet‐induced β‐cell mass expansion in mice.
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- Journal of Diabetes Investigation, 2021, v. 12, n. 9, p. 1545, doi. 10.1111/jdi.13532
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- Article
Clinical and enzymatic phenotypes in congenital hyperinsulinemic hypoglycemia due to glucokinase‐activating mutations: A report of two cases and a brief overview of the literature.
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- Journal of Diabetes Investigation, 2019, v. 10, n. 6, p. 1454, doi. 10.1111/jdi.13072
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- Article
Preliminary screening of mutations in the glucokinase gene of Chinese patients with gestational diabetes.
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- Journal of Diabetes Investigation, 2018, v. 9, n. 1, p. 199, doi. 10.1111/jdi.12664
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- Article
Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β-cells.
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- Journal of Diabetes Investigation, 2016, v. 7, n. 2, p. 171, doi. 10.1111/jdi.12407
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- Article
Conformational transition pathway of R308K mutant glucokinase in the presence of the glucokinase activator YNKGKA4.
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- FEBS Open Bio, 2018, v. 8, n. 8, p. 1202, doi. 10.1002/2211-5463.12255
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- Article
Adaptación de la célula β en dislipemia e insulinoresistencia inducida por dieta rica en sacarosa. Rol de la glucoquinasa.
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- FABICIB: Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, 2010, v. 14, p. 138, doi. 10.14409/fabicib.v14i1.858
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- Article
Characterization of Glucokinase Catalysis from a Pseudo-Dimeric View.
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- Applied Biochemistry & Biotechnology, 2019, v. 189, n. 2, p. 345, doi. 10.1007/s12010-019-02998-z
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- Article
Ethnopharmacological perspectives of glucokinase activators in the treatment of diabetes mellitus.
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- Natural Product Research, 2022, v. 36, n. 11, p. 2962, doi. 10.1080/14786419.2021.1931187
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- Article
Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver M. Jackerott et al.: IR knockout mice overexpressing liver GK.
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- Diabetologia, 2002, v. 45, n. 9, p. 1292, doi. 10.1007/s00125-002-0881-y
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- Article
Early-onset Type II diabetes mellitus in Italian families due to mutations in the genes encoding hepatic nuclear factor 1α and glucokinase.
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- Diabetologia, 2001, v. 44, n. 10, p. 1326, doi. 10.1007/s001250100644
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- Article
High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI.
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- Diabetologia, 2001, v. 44, n. 7, p. 898
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- Article
A high prevalence of glucokinase mutations in gestational diabetic subjects selected by clinical criteria.
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- Diabetologia, 2000, v. 43, n. 2, p. 250, doi. 10.1007/s001250050038
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- Article
Glucokinase activation leads to an unsustained hypoglycaemic effect with hepatic triglyceride accumulation in db/db mice.
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 3, p. 391, doi. 10.1111/dom.14586
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- Article
AMG 151 ( ARRY-403), a novel glucokinase activator, decreases fasting and postprandial glycaemia in patients with type 2 diabetes.
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- Diabetes, Obesity & Metabolism, 2016, v. 18, n. 2, p. 191, doi. 10.1111/dom.12586
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- Article
Exendin-4 regulates glucokinase expression by CaMKK/CaMKIV pathway in pancreatic β-cell line.
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- Diabetes, Obesity & Metabolism, 2009, v. 11, n. 10, p. 939, doi. 10.1111/j.1463-1326.2009.01067.x
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- Article
Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity-onset diabetes of the young (MODY2) patients.
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- Journal of Human Genetics, 2008, v. 53, n. 5, p. 460, doi. 10.1007/s10038-008-0271-5
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- Article