Works matching Gene knockout

Results: 5000

斑马鱼adgrf3a 基因敲除品系的构建.

Published in:

Journal of Laser Biology / Acta Laser Biology Sinica, 2023, v. 32, n. 5, p. 423, doi. 10.3969/j.issn.1007-7146.2023.05.005

By:

杨曙;
伍伟景;
赖若沙;
汪芹;
张康佳;
张勇;
肖自安;
谢鼎华

Publication type:

Article

CRISPR/Cas9 技术联合脂质体转染子宫内膜癌细胞单质粒基因敲除方法首次编辑免疫相关基因 HLA-DRA.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2023, v. 27, n. 15, p. 2356, doi. 10.12307/2023.622

By:

蔡波;
李晓晓;
张凌寒;
刘彦星;
毛跟红

Publication type:

Article

KOnezumi-AID: Automation Software for Efficient Multiplex Gene Knockout Using Target-AID.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13500, doi. 10.3390/ijms252413500

By:

Taki, Taito;
Morimoto, Kento;
Mizuno, Seiya;
Kuno, Akihiro

Publication type:

Article

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells.

Published in:

Biotechnology Letters, 2022, v. 44, n. 1, p. 59, doi. 10.1007/s10529-021-03214-x

By:

Zhu, Xiang-xing;
Pan, Jia-sheng;
Lin, Tao;
Yang, Ye-cheng;
Huang, Qiu-yan;
Yang, Shuai-peng;
Qu, Zi-xiao;
Lin, Zi-sheng;
Wen, Jian-cong;
Yan, Ai-fen;
Feng, Juan;
Liu, Lian;
Zhang, Xiao-li;
Lu, Jia-hong;
Tang, Dong-sheng

Publication type:

Article

甘蔗鞭孢堆黑粉菌原生质体转化 DNA 双片段的基因敲除方法的建立.

Published in:

Mycosystema, 2020, v. 39, n. 12, p. 2314, doi. 10.13346/j.mycosystema.200273

By:

蔡恩平;
梅丹;
张小萌;
孙贤;
李玲玉;
吴熔熔;
邓懿祯;
姜子德;
常长青

Publication type:

Article

C-C chemokine receptor type 3 gene knockout alleviates inflammatory responses in allergic rhinitis model mice by regulating the expression of eosinophil granule proteins and immune factors.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 4, p. 3780, doi. 10.3892/mmr.2018.9380

By:

Zhu, Xinhua;
Liu, Ke;
Wang, Jialin;
Peng, Haisen;
Pan, Qibin;
Wu, Shuhong;
Jiang, Yinli;
Liu, Yuehui

Publication type:

Article

Toll-Like Receptor 4 Gene Knockout Increases the Function of Exogenous Bone Marrow Stem Cells in Ischemic Brain.

Published in:

Indian Journal of Pharmaceutical Sciences, 2022, v. 84, p. 1

By:

DELIAN KONG;
LI, J. R.;
JIE WU;
YANAN WANG;
XIAOHUA WANG;
DONG, S. Y.

Publication type:

Article

Colony-live —a high-throughput method for measuring microbial colony growth kinetics—reveals diverse growth effects of gene knockouts in Escherichia coli.

Published in:

BMC Microbiology, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2180-14-171

By:

Takeuchi, Rikiya;
Tamura, Takeyuki;
Nakayashiki, Toru;
Tanaka, Yuichirou;
Muto, Ai;
Wanner, Barry L.;
Mori, Hirotada

Publication type:

Article

Derivation of Induced Pluripotent Stem Cells Line (RCPCMi009-A-1) with Knockout of the UBE2A Gene Using CRISPR/Cas9 Genome Editing.

Published in:

Russian Journal of Developmental Biology, 2023, v. 54, n. 6, p. 365, doi. 10.1134/S1062360423060048

By:

Khomyakova, E. A.;
Fedorenko, A. V.;
Surdina, A. V.;
Volovikov, E. A.;
Belikova, L. D.;
Zerkalenkova, E. A.;
Lagarkova, M. A.;
Bogomazova, A. N.

Publication type:

Article

SpCas9- and LbCas12a-Mediated DNA Editing Produce Different Gene Knockout Outcomes in Zebrafish Embryos.

Published in:

Genes, 2020, v. 11, n. 7, p. 740, doi. 10.3390/genes11070740

By:

Meshalkina, Darya A.;
Glushchenko, Aleksei S.;
Kysil, Elana V.;
Mizgirev, Igor V.;
Frolov, Andrej

Publication type:

Article

Identifying a Gene Knockout Strategy Using a Hybrid of Simple Constrained Artificial Bee Colony Algorithm and Flux Balance Analysis to Enhance the Production of Succinate and Lactate in Escherichia Coli.

Published in:

Interdisciplinary Sciences: Computational Life Sciences, 2019, v. 11, n. 1, p. 33, doi. 10.1007/s12539-019-00324-z

By:

Hon, Mei Kie;
Mohamad, Mohd Saberi;
Mohamed Salleh, Abdul Hakim;
Choon, Yee Wen;
Mohd Daud, Kauthar;
Remli, Muhammad Akmal;
Ismail, Mohd Arfian;
Omatu, Sigeru;
Sinnott, Richard O.;
Corchado, Juan Manuel

Publication type:

Article

CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172207

By:

Zhang, Yani;
Wang, Yingjie;
Zuo, Qisheng;
Li, Dong;
Zhang, Wenhui;
Wang, Fei;
Ji, Yanqin;
Jin, Jing;
Lu, Zhenyu;
Wang, Man;
Zhang, Chen;
Li, Bichun

Publication type:

Article

P25 Gene Knockout Contributes to Human Epidermal Growth Factor Production in Transgenic Silkworms.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2709, doi. 10.3390/ijms22052709

By:

Wu, Meiyu;
Ruan, Jinghua;
Ye, Xiaogang;
Zhao, Shuo;
Tang, Xiaoli;
Wang, Xiaoxiao;
Li, Huiping;
Zhong, Boxiong;
Davies, T. G. Emyr

Publication type:

Article

PagHK3a 基因敲除对银腺杨抗旱性的影响.

Published in:

Forest Research, 2023, v. 36, n. 5, p. 1, doi. 10.12403/j.1001-1498.20230069

By:

武舒;
王洲;
张明艳;
钟姗辰;
王黎;
苏晓华;
张冰玉

Publication type:

Article

Refining computational inference of gene regulatory networks: integrating knockout data within a multi-task framework.

Published in:

Briefings in Bioinformatics, 2024, v. 25, n. 5, p. 1, doi. 10.1093/bib/bbae361

By:

Cui, Wentao;
Long, Qingqing;
Xiao, Meng;
Wang, Xuezhi;
Feng, Guihai;
Li, Xin;
Wang, Pengfei;
Zhou, Yuanchun

Publication type:

Article

In silico gene knockout prediction using a hybrid of Bat algorithm and minimization of metabolic adjustment.

Published in:

Journal of Integrative Bioinformatics, 2021, v. 18, n. 3, p. 1, doi. 10.1515/jib-2020-0037

By:

Man, Mei Yen;
Mohamad, Mohd Saberi;
Choon, Yee Wen;
Ismail, Mohd Arfian

Publication type:

Article

Gene knockout identification for metabolite production improvement using a hybrid of genetic ant colony optimization and flux balance analysis.

Published in:

Biotechnology & Bioprocess Engineering, 2015, v. 20, n. 4, p. 685, doi. 10.1007/s12257-015-0276-9

By:

Salleh, Abdul;
Mohamad, Mohd;
Deris, Safaai;
Omatu, Sigeru;
Fdez-Riverola, Florentino;
Corchado, Juan

Publication type:

Article

产酸克雷伯氏菌乳酸脱氢酶基因敲除提高2,3-丁二醇产量.

Published in:

China Brewing, 2020, v. 39, n. 11, p. 158, doi. 10.11882/j.issn.0254-5071.2020.11.030

By:

叶广彬;
银联飞;
王长丽;
孙珊珊;
杨睿睿;
葛菁萍

Publication type:

Article

In silico prediction of gene knockout candidates in Escherichia coli genome-scale model for enhanced succinic acid production from glycerol.

Published in:

Current Science (00113891), 2015, v. 108, n. 6, p. 1131

By:

Mienda, Bashir Sajo;
Shamsir, Mohd Shahir;
Illias, Rosli Md

Publication type:

Article

SIN-KNO: A method of gene regulatory network inference using single-cell transcription and gene knockout data.

Published in:

Journal of Bioinformatics & Computational Biology, 2019, v. 17, n. 6, p. N.PAG, doi. 10.1142/S0219720019500355

By:

Wang, Huiqing;
Lian, Yuanyuan;
Li, Chun;
Ma, Yue;
Yan, Zhiliang;
Dong, Chunlin

Publication type:

Article

Knockout of Tyrosine Aminotransferase Gene by Homologous Recombination Arrests Growth and Disrupts Redox Homeostasis in Leishmania Parasite.

Published in:

Parasitology Research, 2022, v. 121, n. 11, p. 3229, doi. 10.1007/s00436-022-07642-0

By:

Sasidharan, Santanu;
Saudagar, Prakash

Publication type:

Article

Generation of markerless and multiple-gene knockout in Glaesserella parasuis based on natural transformation and Flp recombinase.

Published in:

Applied Microbiology & Biotechnology, 2022, v. 106, n. 13-16, p. 5167, doi. 10.1007/s00253-022-11994-z

By:

Xiao, Jing;
Wang, Qiaochu;
Xiao, Kunxue;
Zhu, Wenlong;
Huang, Junhao;
Cai, Xuwang;
Chen, Huanchun;
Xu, Xiaojuan

Publication type:

Article

Cre/loxP 系统应用于毕赤酵母基因敲除的研究进展.

Published in:

Journal of Anhui Agricultural Sciences, 2023, v. 51, n. 15, p. 10, doi. 10.3969/j.issn.0517-6611.2023.15.003

By:

王未鲜;
韩铭海

Publication type:

Article

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model.

Published in:

Orphanet Journal of Rare Diseases, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13023-025-03580-z

By:

Wang, Shunan;
Shen, Ming;
Pang, Bo;
Zhou, Bo;
Yuan, Yuan;
Lu, Mei;
Deng, Xiangling;
Yang, Min;
Liu, Shufang;
Wang, Qiong;
Xue, Mei;
Xia, Qisheng;
Zhang, Zhixin

Publication type:

Article

A Simple Allelic Exchange Method for Efficient Seamless Knockout of Up to 34-kbp-Long Gene Cassettes in Pseudomonas.

Published in:

Applied Biochemistry & Biotechnology, 2024, v. 196, n. 8, p. 5616, doi. 10.1007/s12010-023-04806-1

By:

Han, Feng;
Zhang, Xiaoya;
Chen, Yunfei;
Zhao, Haixia;
Wu, Jieer;
Yu, Yongxin;
Wang, Yongjie

Publication type:

Article

Icariin Promotes Osteogenic Differentiation in a Cell Model with NF1 Gene Knockout by Activating the cAMP/PKA/CREB Pathway.

Published in:

Molecules, 2023, v. 28, n. 13, p. 5128, doi. 10.3390/molecules28135128

By:

Chen, Meng;
Lu, Lianhua;
Cheng, Dong;
Zhang, Jing;
Liu, Xinyong;
Zhang, Jianli;
Zhang, Tianliang

Publication type:

Article

TPK3基因敲除对酿酒酵母耐受性的影响.

Published in:

Food Research & Development, 2021, v. 42, n. 18, p. 153, doi. 10.12161/j.issn.1005-6521.2021.18.023

By:

刘凯毅;
任剑星;
张晓晓;
董胜胜;
董健

Publication type:

Article

Functional understanding of secondary cell wall cellulose synthases in Populustrichocarpa via the Cas9/gRNA‐induced gene knockouts.

Published in:

New Phytologist, 2021, v. 231, n. 4, p. 1478, doi. 10.1111/nph.17338

By:

Xu, Wenjing;
Cheng, Hao;
Zhu, Siran;
Cheng, Jiyao;
Ji, Huanhuan;
Zhang, Baocai;
Cao, Shenquan;
Wang, Chong;
Tong, Guimin;
Zhen, Cheng;
Mu, Liqiang;
Zhou, Yihua;
Cheng, Yuxiang

Publication type:

Article

Effects of CYP2C11 gene knockout on the pharmacokinetics and pharmacodynamics of warfarin in rats.

Published in:

Xenobiotica, 2019, v. 49, n. 12, p. 1478, doi. 10.1080/00498254.2019.1579006

By:

Ye, Huanying;
Sui, Danjuan;
Liu, Wei;
Yuan, Yuannan;
Ouyang, Zhen;
Wei, Yuan

Publication type:

Article

Conversion of hulled into naked barley by Cas endonuclease-mediated knockout of the NUD gene.

Published in:

BMC Plant Biology, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12870-020-02454-9

By:

Gerasimova, Sophia V.;
Hertig, Christian;
Korotkova, Anna M.;
Kolosovskaya, Ekaterina V.;
Otto, Ingrid;
Hiekel, Stefan;
Kochetov, Alex V.;
Khlestkina, Elena K.;
Kumlehn, Jochen

Publication type:

Article

Generation of no‐yellow‐pigment Xenopus tropicalis by slc2a7 gene knockout.

Published in:

Developmental Dynamics, 2021, v. 250, n. 10, p. 1420, doi. 10.1002/dvdy.334

By:

Nakajima, Keisuke;
Shimamura, Masaki;
Furuno, Nobuaki

Publication type:

Article

Effects of l-arabinose efflux on λ Red recombination-mediated gene knockout in multiple-antimicrobial-resistant <italic>Salmonella enterica</italic> serovar Choleraesuis.

Published in:

Archives of Microbiology, 2018, v. 200, n. 2, p. 219, doi. 10.1007/s00203-017-1436-4

By:

Liao, Shi-Wei;
Lee, Jen-Jie;
Ptak, Christopher P.;
Wu, Ying-Chen;
Hsuan, Shih-Ling;
Kuo, Chih-Jung;
Chen, Ter-Hsin

Publication type:

Article

Multiplex gene knockout raises Ala-Gln production by Escherichia coli expressing amino acid ester acyltransferase.

Published in:

Applied Microbiology & Biotechnology, 2023, v. 107, n. 11, p. 3523, doi. 10.1007/s00253-023-12550-z

By:

Jing, Zhanyu;
Xu, Jian;
Liu, Jia;
Du, Cong;
Qi, Jiakun;
Fan, Chao;
Li, Yimin;
Yuan, Wenjie

Publication type:

Article

CRISPR/Cas9-Mediated Knockout of the HuR Gene in U251 Cell Inhibits Japanese Encephalitis Virus Replication.

Published in:

Microorganisms, 2024, v. 12, n. 2, p. 314, doi. 10.3390/microorganisms12020314

By:

Luo, Sai-Qi;
Cao, San-Jie;
Zhao, Qin

Publication type:

Article

glnA 基因敲除对土壤杆菌产可得然胶的影响.

Published in:

Journal of Food Safety & Quality, 2025, v. 16, n. 9, p. 33, doi. 10.19812/j.cnki.jfsq11-5956/ts.20250120006

By:

姚博伟;
武世强;
高红亮;
杨雪霞

Publication type:

Article

Cold-adapted characteristics and gene knockout of alkyl hydroperoxide reductase subunit C in Antarctic Psychrobacter sp. ANT206.

Published in:

World Journal of Microbiology & Biotechnology, 2024, v. 40, n. 11, p. 1, doi. 10.1007/s11274-024-04158-w

By:

Hou, Yanhua;
Qiao, Jiarui;
Hou, Shumiao;
Wang, Yatong;
Wang, Quanfu

Publication type:

Article

Knockout Genes in Bowel Anastomoses: A Systematic Review of Literature Outcomes.

Published in:

Journal of Personalized Medicine, 2024, v. 14, n. 6, p. 553, doi. 10.3390/jpm14060553

By:

Geropoulos, Georgios;
Psarras, Kyriakos;
Koimtzis, Georgios;
Fornasiero, Massimiliano;
Anestiadou, Elissavet;
Geropoulos, Vasileios;
Michopoulou, Anna;
Papaioannou, Maria;
Kouzi-Koliakou, Kokkona;
Galanis, Ioannis

Publication type:

Article

Gene knockout revealed the role of gene feoA in cell growth and division of Lactobacillus delbrueckii subsp. bulgaricus.

Published in:

Archives of Microbiology, 2021, v. 203, n. 6, p. 3541, doi. 10.1007/s00203-021-02345-z

By:

Han, Xue;
Tu, Yuanqiang;
Wu, Huiying;
Zhang, Lijuan;
Zhao, Sainan

Publication type:

Article

Knockout of pde gene in Arthrobacter sp. CGMCC 3584 and transcriptomic analysis of its effects on cAMP production.

Published in:

Bioprocess & Biosystems Engineering, 2020, v. 43, n. 5, p. 839, doi. 10.1007/s00449-019-02280-w

By:

Niu, Huanqing;
Sun, Xinzeng;
Song, Jiarui;
Zhu, Chenjie;
Chen, Yong;
Gao, Nan;
Qu, Xudong;
Ying, Hanjie;
Liu, Dong

Publication type:

Article

Endothelin Receptor A Antagonism and Fetal Growth in Endothelial Nitric Oxide Synthase Gene Knockout Maternal and Fetal Mice.

Published in:

Reproductive Sciences, 2016, v. 23, n. 8, p. 1028, doi. 10.1177/1933719115625839

By:

Luo, Kehuan;
Thaete, Larry G.;
Neerhof, Mark G.

Publication type:

Article

Mosquito E-20-Monooxygenase Gene Knockout Increases Dengue Virus Replication in Aedes aegypti Cells.

Published in:

Viruses (1999-4915), 2024, v. 16, n. 4, p. 525, doi. 10.3390/v16040525

By:

Li, Bo;
Wang, Di;
Xie, Xiaoxue;
Chen, Xiaoli;
Liang, Guorui;
Xing, Dan;
Zhao, Teng;
Wu, Jiahong;
Zhou, Xinyu;
Li, Chunxiao

Publication type:

Article

The gene knockout of angiotensin II type 1a receptor improves high-fat diet-induced obesity in rat via promoting adipose lipolysis.

Published in:

PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0267331

By:

Li, Aiyun;
Shi, Wenjuan;
Wang, Jin;
Wang, Xuejiao;
Zhang, Yan;
Lei, Zhandong;
Jiao, Xiang-Ying

Publication type:

Article

Kaiso Gene Knockout Promotes Somatic Cell Reprogramming.

Published in:

Biochemistry (00062979), 2019, v. 84, n. 3, p. 283, doi. 10.1134/S0006297919030106

By:

Kaplun, D. S.;
Fok, R. E.;
Korostina, V. S.;
Prokhortchouk, E. B.;
Zhenilo, S. V.

Publication type:

Article

ACOT11 基因敲除后促进 UUO 模型小鼠肾脏组织纤维化.

Published in:

Progress in Modern Biomedicine, 2025, v. 25, n. 9, p. 1441, doi. 10.13241/j.cnki.pmb.2025.09.001

By:

柯波亮;
何雏江;
唐麒麟;
牟伟明;
庄严;
邵怡

Publication type:

Article

TRB3 基因敲除减轻糖尿病小鼠中骨骼肌萎缩和纤维化的研究.

Published in:

Progress in Modern Biomedicine, 2023, v. 23, n. 14, p. 2620, doi. 10.13241/j.cnki.pmb.2023.14.004

By:

侯静雯;
张玉婷;
朱新华;
张蕾;
张晓阳

Publication type:

Article

An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue.

Published in:

PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0228910

By:

Jin, Jiankang;
Xu, Yan;
Huo, Longfei;
Ma, Lang;
Scott, Ailing W.;
Pizzi, Melissa Pool;
Li, Yuan;
Wang, Ying;
Yao, Xiaodan;
Song, Shumei;
Ajani, Jaffer A.

Publication type:

Article

Effect of the THBS1 Gene Knockout on the Radiation-Induced Cellular Response in a Model System In Vitro.

Published in:

Russian Journal of Genetics, 2020, v. 56, n. 5, p. 618, doi. 10.1134/S1022795420050129

By:

Savchenko, R. R.;
Vasilyev, S. A.;
Fishman, V. S.;
Sukhikh, E. S.;
Sukhikh, L. G.;
Murashkina, A. A.;
Lebedev, I. N.

Publication type:

Article

Knockout Mutations in the Genes Encoding Phosphate Transporters Impair Adaptation of Saccharomyces cerevisiae to Ethanol Consumption.

Published in:

Microbiology (00262617), 2024, v. 93, n. 5, p. 610, doi. 10.1134/S0026261724605943

By:

Ledova, L. A.;
Ryazanova, L. P.;
Kulakovskaya, T. V.

Publication type:

Article

Adaptation of the yeast gene knockout collection is near-perfectly predicted by fitness and diminishing return epistasis.

Published in:

G3: Genes | Genomes | Genetics, 2022, v. 12, n. 11, p. 1, doi. 10.1093/g3journal/jkac240

By:

Persson, Karl;
Stenberg, Simon;
Tamás, Markus J.;
Warringer, Jonas

Publication type:

Article

Metabolic engineering of Escherichia coli BW25113 for the production of 5-Aminolevulinic Acid based on CRISPR/Cas9 mediated gene knockout and metabolic pathway modification.

Published in:

Journal of Biological Engineering, 2022, v. 16, n. 1, p. 1, doi. 10.1186/s13036-022-00307-7

By:

Ye, Changchuan;
Yang, Yuting;
Chen, Xi;
Yang, Lijie;
Hua, Xia;
Yang, Mengjie;
Zeng, Xiangfang;
Qiao, Shiyan

Publication type:

Article