Works matching Drug development

Results: 5000

Implications of Pediatric Initiatives on CNS Drug Development for All Ages--2020 and Beyond: Second of Three Sets of Expanded Proceedings from the 2020 ISCTM Autumn Conference on Pediatric Drug Development.

Published in:

Innovations in Clinical Neuroscience, 2023, v. 20, n. 1-3, p. 18

By:

PANDINA, GAHAN;
BUSNER, JOAN;
HORRIGAN, JOSEPH P.;
MCSHERRY, CHRISTINE;
BATEMAN-HOUSE, ALISON;
PANI, LUCA;
KANDO, JUDITH

Publication type:

Article

Special Challenges in Pediatric Drug Development: First of Three Sets of Expanded Proceedings from the ISCTM Autumn Conference on Pediatric Drug Development.

Published in:

Innovations in Clinical Neuroscience, 2023, v. 20, n. 1-3, p. 13

By:

HARVEY, PHILIP D.;
BUSNER, JOAN;
PANDINA, GAHAN;
TAYLOR, H. GERRY;
GRABB, MEG;
JIMENEZ-SHAHED, JOOHI

Publication type:

Article

Role of Model‐Informed Drug Development in Pediatric Drug Development, Regulatory Evaluation, and Labeling.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, p. S104, doi. 10.1002/jcph.1478

By:

Bi, Youwei;
Liu, Jiang;
Li, Lingjue;
Yu, Jingyu;
Bhattaram, Atul;
Bewernitz, Michael;
Li, Ruo‐jing;
Liu, Chao;
Earp, Justin;
Ma, Lian;
Zhuang, Luning;
Yang, Yuching;
Zhang, Xinyuan;
Zhu, Hao;
Wang, Yaning

Publication type:

Article

Role of Model‐Informed Drug Development in Pediatric Drug Development, Regulatory Evaluation, and Labeling.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, p. S104, doi. 10.1002/jcph.1478

By:

Bi, Youwei;
Liu, Jiang;
Li, Lingjue;
Yu, Jingyu;
Bhattaram, Atul;
Bewernitz, Michael;
Li, Ruo‐jing;
Liu, Chao;
Earp, Justin;
Ma, Lian;
Zhuang, Luning;
Yang, Yuching;
Zhang, Xinyuan;
Zhu, Hao;
Wang, Yaning

Publication type:

Article

器官芯片与工程化人体组织在药物研发中的应用前景.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2020, v. 24, n. 29, p. 4717, doi. 10.3969/j.issn.2095-4344.2711

By:

陈沛杉;
张海燕

Publication type:

Article

Cancer drug development in Europe: a selection of new agents under development at the European Drug Development Network.

Published in:

2003

By:

Lacombe, D.;
Butler-Smith, A.;
Therasse, P.;
Fumoleau, P.;
Burtles, S.;
Calvert, H.;
Marsoni, S.;
Sessa, C.;
Verweij, J.

Publication type:

journal article

Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses.

Published in:

Expert Review of Clinical Pharmacology, 2023, v. 16, n. 12, p. 1201, doi. 10.1080/17512433.2023.2288171

By:

Goulooze, Sebastiaan C.;
Vis, Peter W.;
Krekels, Elke H.J.;
Knibbe, Catherijne A.J.

Publication type:

Article

Model-based clinical drug development in the past, present and future: a commentary.

Published in:

British Journal of Clinical Pharmacology, 2015, v. 79, n. 1, p. 108, doi. 10.1111/bcp.12341

By:

Kimko, Holly;
Pinheiro, José

Publication type:

Article

Patient Centricity: Design and Conduct of Clinical Trials in Orphan Diseases: Third of Three Sets of Expanded Proceedings from the 2020 ISCTM Autumn Conference on Pediatric Drug Development.

Published in:

Innovations in Clinical Neuroscience, 2023, v. 20, n. 1-3, p. 25

By:

BUSNER, JOAN;
PANDINA, GAHAN;
DAY, SIMON;
MAHABLESHWARKAR, ATUL;
KEMPF, LUCAS;
SHEEAN, MARIA;
DUNN, JUDITH

Publication type:

Article

Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations.

Published in:

Applied Sciences (2076-3417), 2020, v. 10, n. 7, p. 2376, doi. 10.3390/app10072376

By:

van Wijk, Rob C.;
Ayoun Alsoud, Rami;
Lennernäs, Hans;
Simonsson, Ulrika S. H.

Publication type:

Article

Review: Role of Model-Informed Drug Development Approaches in the Lifecycle of Drug Development and Regulatory Decision-Making.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 8, p. 1669, doi. 10.1007/s11095-022-03288-w

By:

Madabushi, Rajanikanth;
Seo, Paul;
Zhao, Liang;
Tegenge, Million;
Zhu, Hao

Publication type:

Article

Collaboration in Development of New Drugs.

Published in:

Production & Operations Management, 2021, v. 30, n. 11, p. 3943, doi. 10.1111/poms.13377

By:

Tian, Zhili;
Gurnani, Haresh;
Xu, Yi

Publication type:

Article

Drug-induced QT interval prolongation: regulatory perspectives and drug development.

Published in:

Annals of Medicine, 2004, v. 36, p. 47, doi. 10.1080/17431380410032445

By:

Shah, Rashmi R

Publication type:

Article

Patient-centered drug development and the Learning Health System.

Published in:

Learning Health Systems, 2017, v. 1, n. 3, p. n/a, doi. 10.1002/lrh2.10027

By:

Crawford, Laura S.;
Matczak, Gerald J.;
Moore, Erin M.;
Haydar, Rita A.;
Coderre, Pauline T.

Publication type:

Article

Introduction to the mini special issue on next generation drug discovery and development: rethinking translational pharmacology for accelerated drug development.

Published in:

Drug Metabolism Reviews, 2021, v. 53, n. 2, p. 171, doi. 10.1080/03602532.2021.1909614

By:

Nwabufo, Chukwunonso K.

Publication type:

Article

Inefficiencies and Patient Burdens in the Development of the Targeted Cancer Drug Sorafenib: A Systematic Review.

Published in:

PLoS Biology, 2017, v. 15, n. 2, p. 1, doi. 10.1371/journal.pbio.2000487

By:

Mattina, James;
Carlisle, Benjamin;
Hachem, Yasmina;
Fergusson, Dean;
Kimmelman, Jonathan

Publication type:

Article

Utility of physiologically based pharmacokinetic (PBPK) modeling in oncology drug development and its accuracy: a systematic review.

Published in:

European Journal of Clinical Pharmacology, 2018, v. 74, n. 11, p. 1365, doi. 10.1007/s00228-018-2513-6

By:

Saeheng, Teerachat;
Na-Bangchang, Kesara;
Karbwang, Juntra

Publication type:

Article

Modelling and simulation as research tools in paediatric drug development.

Published in:

European Journal of Clinical Pharmacology, 2011, v. 67, p. 75, doi. 10.1007/s00228-010-0974-3

By:

Bellanti, Francesco;
Della Pasqua, Oscar

Publication type:

Article

Regulatory scientific advice in drug development: does company size make a difference?

Published in:

European Journal of Clinical Pharmacology, 2011, v. 67, n. 2, p. 157, doi. 10.1007/s00228-010-0919-x

By:

Putzeist, Michelle;
Mantel-Teeuwisse, Aukje;
Gispen-De Wied, Christine;
Hoes, Arno;
Leufkens, Hubert

Publication type:

Article

An analysis of the clinical development of drugs in Norway for the year 2000: the completion of research and publication of results.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 3, p. 315, doi. 10.1007/s00228-008-0601-8

By:

Hole, Ola P.;
Nitter-Hauge, Sigurd;
Cederkvist, Henrik R.;
Winther, Finn Ø.

Publication type:

Article

Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 5/6, p. 357, doi. 10.1007/s00228-003-0643-x

By:

Bergström, Mats;
Grahnén, Anders;
Långström, Bengt

Publication type:

Article

DRUGS: STAGES OF DRUG DEVELOPMENT AND METHODS TO CONTROL THE HIGH USAGE OF DRUGS.

Published in:

i-Manager's Journal on Life Sciences (JLS), 2023, v. 2, n. 1, p. 31, doi. 10.26634/jls.2.1.19260

By:

JYOTI;
TULI, BHUMIKA;
KUMAR, SANTOSH

Publication type:

Article

Improving the Drug Development Pipeline for Mycobacteria: Modelling Antibiotic Exposure in the Hollow Fibre Infection Model.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 12, p. 1515, doi. 10.3390/antibiotics10121515

By:

Maitra, Arundhati;
Solanki, Priya;
Sadouki, Zahra;
McHugh, Timothy D.;
Kloprogge, Frank

Publication type:

Article

Ethical aspects in the use of artificial intelligence in the process of drug development.

Published in:

Brasov Medical Journal / Jurnal Medical Brasovean, 2023, n. 2, p. 53, doi. 10.31926/jmb.2023.2.8

By:

Pitel, Ecaterina;
Leașu, Florin;
Nicolau, Andrada;
Rogozea, Liliana

Publication type:

Article

Analysis of new drugs whose clinical development and regulatory approval were hampered during their introduction in Japan.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2013, v. 38, n. 4, p. 309, doi. 10.1111/jcpt.12064

By:

Asada, R.;
Shimizu, S.;
Ono, S.;
Ito, T.;
Shimizu, A.;
Yamaguchi, T.

Publication type:

Article

Impact of biomarker usage on oncology drug development.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2013, v. 38, n. 1, p. 62, doi. 10.1111/jcpt.12008

By:

Hayashi, K.;
Masuda, S.;
Kimura, H.

Publication type:

Article

Pediatric oncology drug development and dosage optimization.

Published in:

Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2023.1235947

By:

Cheung, S. Y. Amy;
Hay, Justin L.;
Yu-Wei Lin;
de Greef, Rik;
Bullock, Julie

Publication type:

Article

Project Optimus, an FDA initiative: Considerations for cancer drug development internationally, from an academic perspective.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1144056

By:

Murphy, Ravindhi;
Halford, Sarah;
Symeonides, Stefan Nicholas

Publication type:

Article

Insights into immuno-oncology drug development landscape with focus on bone metastasis.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1121878

By:

Kähkönen, Tiina E.;
Halleen, Jussi M.;
MacRitchie, Gary;
Andersson, Ronnie M.;
Bernoulli, Jenni

Publication type:

Article

Advances in orphan drug development: Time to change the status and stereotype.

Published in:

Perspectives in Clinical Research, 2022, v. 13, n. 3, p. 123, doi. 10.4103/picr.picr_193_21

By:

Thakur, Sayanta

Publication type:

Article

Diabetes mellitus: Exploring the challenges in the drug development process.

Published in:

Perspectives in Clinical Research, 2012, v. 3, n. 3, p. 109, doi. 10.4103/2229-3485.100660

By:

Vaz, Julius A.;
Patnaik, Ashis

Publication type:

Article

Is the priority review voucher program stimulating new drug development for tropical diseases?

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 8, p. 1, doi. 10.1371/journal.pntd.0006695

By:

Kerr, Kirk W.;
Henry, Thomas C.;
Miller, Kathleen L.

Publication type:

Article

The role of adaptive trial designs in drug development.

Published in:

Expert Review of Clinical Pharmacology, 2017, v. 10, n. 7, p. 727, doi. 10.1080/17512433.2017.1321985

By:

Curtin, François;
Heritier, Stephane

Publication type:

Article

Drug development study designs have reached the danger zone.

Published in:

Expert Review of Clinical Pharmacology, 2013, v. 6, n. 6, p. 589, doi. 10.1586/17512433.2013.841539

By:

Getz, Kenneth;
Campo, Rafael

Publication type:

Article

The impact of molecular targets in cancer drug development: major hurdles and future strategies.

Published in:

Expert Review of Clinical Pharmacology, 2013, v. 6, n. 1, p. 23, doi. 10.1586/ECP.12.71

By:

Hebar, Alexandra;
Valent, Peter;
Selzer, Edgar

Publication type:

Article

Restoration of positive mood states in major depression as a potential drug development target.

Published in:

2014

By:

Lane, Roger M

Publication type:

journal article

Pharmacological models in healthy volunteers: their use in the clinical development of psychotropic drugs.

Published in:

Journal of Psychopharmacology, 2007, v. 21, n. 3, p. 272, doi. 10.1177/0269881107077733

By:

Gilles, Christian;
Luthringer, Remy

Publication type:

Article

Towards an appropriate framework to facilitate responsible inclusion of pregnant women in drug development programs.

Published in:

2018

By:

Roes, Kit C. B.;
van der Zande, Indira S. E.;
van Smeden, Maarten;
van der Graaf, Rieke

Publication type:

journal article

Introduction to Special Issue on Ocular Pathology and Drug Development.

Published in:

Toxicologic Pathology, 2021, v. 49, n. 3, p. 417, doi. 10.1177/0192623320986558

By:

Ramos, Meg F.;
Schafer, Kenneth A.;
Sorden, Steven D.

Publication type:

Article

Can the COVID-19 Pandemic Disrupt the Current Drug Development Practices?

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5457, doi. 10.3390/ijms22115457

By:

Won, Jung-Hyun;
Lee, Howard

Publication type:

Article

Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1550, doi. 10.3390/ijms18071550

By:

Bootorabi, Fatemeh;
Manouchehri, Hamed;
Changizi, Reza;
Barker, Harlan;
Palazzo, Elisabetta;
Saltari, Annalisa;
Parikka, Mataleena;
Pincelli, Carlo;
Aspatwar, Ashok

Publication type:

Article

Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.

Published in:

Cardiovascular Drugs & Therapy, 2017, v. 31, n. 4, p. 445, doi. 10.1007/s10557-017-6739-9

By:

Povsic, Thomas;
Scott, Rob;
Mahaffey, Kenneth;
Blaustein, Robert;
Edelberg, Jay;
Lefkowitz, Martin;
Solomon, Scott;
Fox, Jonathan;
Healy, Kevin;
Khakoo, Aarif;
Losordo, Douglas;
Malik, Fady;
Monia, Brett;
Montgomery, Rusty;
Riesmeyer, Jeffrey;
Schwartz, Gregory;
Zelenkofske, Steven;
Wu, Joseph;
Wasserman, Scott;
Roe, Matthew

Publication type:

Article

A Pediatric Research Imperative: Addressing Neonates in Drug Development Through Understanding Neonatal Clinical Pharmacology.

Published in:

Journal of Pediatric Pharmacology & Therapeutics, 2025, v. 30, n. 1, p. 8, doi. 10.5863/1551-6776-30.1.8

By:

Massaro, An N.;
Fletcher, Elimika Pfuma;
Madabushi, Rajanikanth;
Baer, Gerri;
Green, Dionna

Publication type:

Article

The Revolution in Pediatric Drug Development and Drug Use: Therapeutic Orphans No More.

Published in:

Journal of Pediatric Pharmacology & Therapeutics, 2020, v. 25, n. 7, p. 565, doi. 10.5863/1551-6776-25.7.565

By:

Burckart, Gilbert J.;
Clara Kim

Publication type:

Article

Practices of patient engagement in drug development: a systematic scoping review.

Published in:

Research Involvement & Engagement, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s40900-022-00364-8

By:

Zvonareva, Olga;
Craveț, Constanța;
Richards, Dawn P.

Publication type:

Article

Toxin to medicine and bioisosterism in drug development: a study of the discovery and development of ACE inhibitors from snake venom.

Published in:

Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2021, v. 66, n. 2, p. 3

By:

Oladipupo, Akolade R.

Publication type:

Article

Standardising Patient Engagement in Drug Development: The Emerging, yet Already Noteworthy Case of Patient Focused Medicines Development (PFMD) and its Materials.

Published in:

Science & Technology Studies, 2025, v. 38, n. 1, p. 25

By:

Egher, Claudia;
Zvonareva, Olga

Publication type:

Article

Optimizing drug development of anti-cancer drugs in children using modelling and simulation.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 76, n. 1, p. 30, doi. 10.1111/bcp.12062

By:

Hasselt, Johan G.C.;
Eijkelenburg, Natasha K.A.;
Beijnen, Jos H.;
Schellens, Jan H.M.;
Huitema, Alwin D.R.

Publication type:

Article

Drug development in oncology: classical cytotoxics and molecularly targeted agents.

Published in:

British Journal of Clinical Pharmacology, 2006, v. 62, n. 1, p. 15, doi. 10.1111/j.1365-2125.2006.02713.x

By:

Kummar, Shivaani;
Gutierrez, Martin;
Doroshow, James H;
Murgo, Anthony J.

Publication type:

Article

The teaching of drug development to medical students: collaboration between the pharmaceutical industry and medical school.

Published in:

British Journal of Clinical Pharmacology, 2005, v. 59, n. 4, p. 464, doi. 10.1111/j.1365-2125.2005.02374.x

By:

Stanley, A. G.;
Jackson, D.;
Barnett, D. B.

Publication type:

Article