Works matching Diindolylmethane

Results: 134

Antiproliferative and anti-inflammatory properties of diindolylmethane and lupeol against N-butyl-N-(4-hydroxybutyl) nitrosamine induced bladder carcinogenesis in experimental rats.

Published in:

Human & Experimental Toxicology, 2016, v. 35, n. 6, p. 685, doi. 10.1177/0960327115597985

By:

Prabhu, B.;
Balakrishnan, D.;
Sundaresan, S.

Publication type:

Article

3,3 diindolylmethane leads to apoptosis, decreases sperm quality, affects blood estradiol 17 β and testosterone, oestrogen (α and β) and androgen receptor levels in the reproductive system in male rats.

Published in:

Andrologia, 2016, v. 48, n. 10, p. 1155, doi. 10.1111/and.12554

By:

Aksu, E. H.;
Akman, O.;
Ömür, A. D.;
Karakuş, E.;
Can, İ.;
Kandemir, F. M.;
Dorman, E.;
Uçar, Ö.

Publication type:

Article

INHIBITION OF ODORANT-INDUCED SIGNAL TRANSDUCTION BY DIINDOLYLMETHANE, A FOOD-DERIVED BIOACTIVE MOLECULE.

Published in:

Current Topics in Nutraceutical Research, 2013, v. 11, n. 3, p. 91

By:

Yeo Cho Yoon;
Shuaiyu Wang;
Sung-Hee Kim;
Mi-Jeong Sung;
Jin-Taek Hwang;
Min Jung Kim;
Mee-Ra Rhyu;
Jae-Ho Park

Publication type:

Article

Synthesis of novel benzimidazole-diindolylmethane hybrid compounds within the green chemistry context.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2017, v. 2017, p. 210, doi. 10.3998/ark.5550190.p009.971

By:

Penieres-Carrillo, José Guillermo;
Luna-Mora, Ricardo Alfredo;
López-Cortés, José Guadalupe;
Ortega-Jiménez, Fernando;
Valdez-Rojas, José Ernesto;
García-Estrada, José Guadalupe;
Fernández-Aulis, Fernanda;
Álvarez-Toledano, Cecilio

Publication type:

Article

Exploration of the Chiral Recognition of Sugar-Based Diindolylmethane Receptors: Anion and Receptor Structures.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 46, p. 16585, doi. 10.1002/chem.201502932

By:

Granda, Jarosław M.;
Jurczak, Janusz

Publication type:

Article

Synthesis of diindolylmethane (DIM) bearing thiadiazole derivatives as a potent urease inhibitor.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64729-3

By:

Taha, Muhammad;
Rahim, Fazal;
Khan, Aftab Ahmad;
Anouar, El Hassane;
Ahmed, Naveed;
Shah, Syed Adnan Ali;
Ibrahim, Mohamed;
Zakari, Zainul Amiruddin

Publication type:

Article

A Possible Association of Diindolylmethane with Pulmonary Embolism and Deep Venous Thrombosis.

Published in:

2016

By:

Bui, Peter V.;
Moualla, Maan;
Upson, Dona J.

Publication type:

Case Study

Novel Para-Phenyl Substituted Diindolylmethanes Protect Against MPTP Neurotoxicity and Suppress Glial Activation in a Mouse Model of Parkinson’s Disease.

Published in:

Toxicological Sciences, 2015, v. 143, n. 2, p. 360, doi. 10.1093/toxsci/kfu236

By:

De Miranda, Briana R.;
Popichak, Katriana A.;
Hammond, Sean L.;
Miller, James A.;
Safe, Stephen;
Tjalkens, Ronald B.

Publication type:

Article

A Tandem Hydroformylation‐Organocatalyzed Friedel‐Crafts Reaction for the Synthesis of Diindolylmethanes.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 26, p. 1, doi. 10.1002/chem.202400188

By:

Miller, Lukas;
Bauer, Felix;
Breit, Bernhard

Publication type:

Article

Diindolylmethane and Lupeol therapy halt tumor development on experimental urothelial carcinogenesis.

Published in:

Journal of Experimental Therapeutics & Oncology, 2020, v. 13, n. 3, p. 185

By:

Prabhu, Bhoopathy;
Sivakumar, Annamalai;
Padma, Ramasamy;
Manikandan, Elayaperumal;
Sri Nisha, Jagathrakshakan;
Sundaresan, Sivapatham

Publication type:

Article

Diindolylmethane and Lupeol Modulates Apoptosis and Cell Proliferation in N-Butyl-N-(4-Hydroxybutyl) Nitrosamine Initiated and Dimethylarsinic Acid Promoted rat Bladder Carcinogenesis.

Published in:

Pathology & Oncology Research, 2016, v. 22, n. 4, p. 747, doi. 10.1007/s12253-016-0054-9

By:

Prabhu, Bhoopathy;
Sivakumar, Annamalai;
Sundaresan, Sivapatham

Publication type:

Article

Mutation analysis and molecular modeling for the investigation of ligand-binding modes of GPR84.

Published in:

Journal of Biochemistry, 2015, v. 157, n. 5, p. 311, doi. 10.1093/jb/mvu075

By:

Yoshiaki Nikaido;
Yuuta Koyama;
Yasushi Yoshikawa;
Toshio Furuya;
Shigeki Takeda

Publication type:

Article

Effect of diindolylmethane on Ca movement and viability in HA59T human hepatoma cells.

Published in:

Archives of Toxicology, 2011, v. 85, n. 10, p. 1257, doi. 10.1007/s00204-011-0670-9

By:

Cheng, Jin-Shiung;
Shu, Su-Shung;
Kuo, Chun-Chi;
Chou, Chiang-Ting;
Tsai, Wei-Lun;
Fang, Yi-Chien;
Kuo, Li-Ni;
Yeh, Jeng-Hsien;
Chen, Wei-Chuan;
Chien, Jau-Min;
Lu, Ti;
Pan, Chih-Chuan;
Cheng, He-Hsiung;
Chai, Kuo-Liang;
Jan, Chung-Ren

Publication type:

Article

A controlled safety study of diindolylmethane in the immature rat model.

Published in:

Laryngoscope, 2009, v. 119, n. 9, p. 1803, doi. 10.1002/lary.20526

By:

Elackattu, Alphi P.;
Feng, Lining;
Wang, Zhi

Publication type:

Article

An Experimental Study of the Effect of Diindolylmethane on Alveolocyte and Hepatocyte Adhesion Strength in Mice.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 168, n. 1, p. 45, doi. 10.1007/s10517-019-04642-6

By:

Kiselev, V. I.;
Sukhikh, G. T.;
Pchelintseva, O. I.;
Udut, V. V.;
Kuznetsov, I. N.;
Drukh, V. M.

Publication type:

Article

Protective effect of diindolylmethane‐enriched dietary cabbage against doxorubicin‐induced cardiotoxicity in mice.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 6, p. 874, doi. 10.1002/jat.4588

By:

Natesh, Jagadish;
Mondal, Priya;
Penta, Dhanamjai;
Mukhlis, Yahya;
Haware, Devendra Jaganath;
Meeran, Syed Musthapa

Publication type:

Article

Indole-3 Carbinol and Diindolylmethane Mitigated β-Amyloid-Induced Neurotoxicity and Acetylcholinesterase Enzyme Activity: In Silico, In Vitro, and Network Pharmacology Study.

Published in:

Diseases, 2024, v. 12, n. 8, p. 184, doi. 10.3390/diseases12080184

By:

Ramakrishna, Kakarla;
Karuturi, Praditha;
Siakabinga, Queen;
T.A., Gajendra;
Krishnamurthy, Sairam;
Singh, Shreya;
Kumari, Sonia;
Kumar, G. Siva;
Sobhia, M. Elizabeth;
Rai, Sachchida Nand

Publication type:

Article

Effect of diindolylmethane on Ca2+ homeostasis and viability in MDCK renal tubular cells.

Published in:

Human & Experimental Toxicology, 2013, v. 32, n. 4, p. 344, doi. 10.1177/0960327112462727

By:

Fang, Y-C;
Chou, C-T;
Chi, C-C;
Lin, K-L;
Li, Y-D;
Cheng, H-H;
Lu, Y-C;
Cheng, J-S;
Kuo, C-C;
Jan, C-R

Publication type:

Article

Unveiling the Multifaceted Pharmacological Actions of Indole-3-Carbinol and Diindolylmethane: A Comprehensive Review.

Published in:

Plants (2223-7747), 2025, v. 14, n. 5, p. 827, doi. 10.3390/plants14050827

By:

Srikanth, Yadava;
Reddy, Dontiboina Harikrishna;
Anusha, Vinjavarapu Lakshmi;
Dumala, Naresh;
Viswanadh, Matte Kasi;
Chakravarthi, Guntupalli;
Nalluri, Buchi N.;
Yadagiri, Ganesh;
Ramakrishna, Kakarla

Publication type:

Article

Synthesis of Diindolylmethanes (DIMs) Catalyzed by Silicotungstic Acid by Grinding Method.

Published in:

E-Journal of Chemistry, 2010, v. 7, n. 3, p. 922, doi. 10.1155/2010/986980

By:

Ji-Tai Li;
Shao-Feng Sun

Publication type:

Article

2,3,7,8-Tetrachlorodibenzo-p-dioxin and Diindolylmethanes Differentially Induce Cytochrome P450 1A1, 1B1, and 19 in H295R Human Adrenocortical Carcinoma Cells.

Published in:

Toxicological Sciences, 2001, v. 61, n. 1, p. 40, doi. 10.1093/toxsci/61.1.40

By:

Sanderson, J. Thomas;
Slobbe, Lennert;
Lansbergen, Gideon W. A.;
Safe, Stephen;
Van den Berg, Martin

Publication type:

Article

Carbophilic 3-Component Cascades: Access to Complex Bioactive Cyclopropyl Diindolylmethanes.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 6, p. 2180, doi. 10.1002/chem.201202647

By:

Groome, Nigel M.;
Elboray, Elghareeb E.;
Inman, Martyn W.;
Dondas, H. Ali;
Phillips, Roger M.;
Kilner, Colin;
Grigg, Ronald

Publication type:

Article

SYNTHESIS OF DIINDOLYLMETHANES - MONTMORLLONITE CLAY K10 AND KSF CATALYZED CONDENSATION OF INDOLE WITH IMINES.

Published in:

Heterocyclic Communications, 2005, v. 11, n. 5, p. 427

By:

Xin-Liang Feng;
Ye Zhang;
Zheng-Huan Lin;
Cheng-Xue Zhao

Publication type:

Article

Regulation of Janus-activated kinase-2 (JAK2) by diindolylmethane in ovarian cancer in vitro and in vivo.

Published in:

Drug Discoveries & Therapeutics, 2012, v. 6, n. 2, p. 94, doi. 10.5582/ddt.2012.v6.2.94

By:

Kandala, Prabodh K.;
Srivastava, Sanjay K.

Publication type:

Article

A DFT Study of the Geometrical, Spectroscopical and Reactivity Properties of Diindolylmethane-Phenylboronic Acid Hybrids.

Published in:

Molecules, 2017, v. 22, n. 10, p. 1744, doi. 10.3390/molecules22101744

By:

Fragoso-Medina, Amira Jalil;
Escobedo-González, René Gerardo;
Nicolás-Vázquez, María Inés;
Arroyo-Razo, Gabriel Arturo;
Noguez-Córdova, María Olivia;
Miranda-Ruvalcaba, René

Publication type:

Article

Indole macrocycles formed by diindolylmethane ring closure.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2022, v. 2022, p. 70, doi. 10.24820/ark.5550190.p011.708

By:

Purwono, Bambang;
Kumar, Naresh;
Black, David StC.

Publication type:

Article

Pharmacokinetics and pharmacodynamics of 3,3′-diindolylmethane (DIM) in regulating gene expression of phase II drug metabolizing enzymes.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2015, v. 42, n. 4, p. 401, doi. 10.1007/s10928-015-9421-5

By:

Wu, Tien-Yuan;
Huang, Ying;
Zhang, Chengyue;
Su, Zheng-Yuan;
Boyanapalli, Sarandeep;
Khor, Tin;
Wang, Hu;
Lin, Hongxia;
Gounder, Murugesan;
Kagan, Leonid;
Androulakis, Ioannis;
Kong, Ah-Ng

Publication type:

Article

Anti-Cancer and Other Biological Effects of a Dietary Compound 3,3ʹ-Diindolylmethane Supplementation: A Systematic Review of Human Clinical Trials.

Published in:

Nutrition & Dietary Supplements, 2020, v. 12, p. 123, doi. 10.2147/NDS.S261577

By:

Amare, Dagnachew Eyachew

Publication type:

Article

Diindolylmethane Inhibits Cadmium-Induced Autophagic Cell Death via Regulation of Oxidative Stress in HEL299 Human Lung Fibroblasts.

Published in:

Molecules, 2022, v. 27, n. 16, p. 5215, doi. 10.3390/molecules27165215

By:

Jung, Yeon-Seop;
Lee, Ho Jeong;
Hyun, Moonjung;
Kim, Hye-Jin;
Kim, Je-Hein;
Hwang, Kwang-Hyun;
Kim, Woong-Soo;
Choi, Jungil;
Heo, Jeong Doo

Publication type:

Article

Effect of diindolylmethane supplementation on low-grade cervical cytological abnormalities: double-blind, randomised, controlled trial.

Published in:

British Journal of Cancer, 2012, v. 106, n. 1, p. 45, doi. 10.1038/bjc.2011.496

By:

Castañon, A;
Tristram, A;
Mesher, D;
Powell, N;
Beer, H;
Ashman, S;
Rieck, G;
Fielder, H;
Fiander, A;
Sasieni, P

Publication type:

Article

Investigating the Inhibition of Diindolylmethane Derivatives on SARS‐CoV‐2 Main Protease.

Published in:

Journal of Molecular Recognition, 2024, v. 37, n. 6, p. 1, doi. 10.1002/jmr.3101

By:

Li, Wenjin;
Chang, Xiaoyu;
Zhou, Hang;
Yu, Wenquan;
Wang, Ruiyong;
Chang, Junbiao

Publication type:

Article

Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice.

Published in:

Carcinogenesis, 2013, v. 34, n. 4, p. 841, doi. 10.1093/carcin/bgs390

By:

Qian, Xuemin;
Song, Jung Min;
Melkamu, Tamene;
Upadhyaya, Pramod;
Kassie, Fekadu

Publication type:

Article

Selective Organocatalytic Synthesis of 3‐Methylindoles and Diindolylmethanes through Reductive Methylation of Indoles with CO<sub>2</sub>.

Published in:

ChemSusChem, 2025, v. 18, n. 13, p. 1, doi. 10.1002/cssc.202500594

By:

Zhang, He;
Wu, Rongpei;
Gao, Ke

Publication type:

Article

Activation of COUP-TFI by a Novel Diindolylmethane Derivative.

Published in:

Cells (2073-4409), 2019, v. 8, n. 3, p. 220, doi. 10.3390/cells8030220

By:

Yoon, Kyungsil;
Chen, Chien-Cheng;
Orr, Asuka A.;
Barreto, Patricia N.;
Tamamis, Phanourios;
Safe, Stephen

Publication type:

Article

Dietary Diindolylmethane Enhances the Therapeutic Effect of Centchroman in Breast Cancer by Inhibiting Neoangiogenesis.

Published in:

Nutrition & Cancer, 2023, v. 75, n. 2, p. 734, doi. 10.1080/01635581.2022.2143825

By:

Penta, Dhanamjai;
Natesh, Jagadish;
Mondal, Priya;
Meeran, Syed Musthapa

Publication type:

Article

Novel Schiff base's complex as a green catalyst for the synthesis of diindolylmethanes under ultrasonics irradiation.

Published in:

Russian Journal of General Chemistry, 2013, v. 83, n. 12, p. 2370, doi. 10.1134/S1070363213120293

By:

Nikpassand, M.;
Zare Fekri, L.;
Sharafi, Sh.

Publication type:

Article

Employing Dietary Comparators to Perform Risk Assessments for Anti-Androgens Without Using Animal Data.

Published in:

Toxicological Sciences, 2019, v. 167, n. 2, p. 375, doi. 10.1093/toxsci/kfy245

By:

Dent, Matthew P;
Li, Hequn;
Carmichael, Paul L;
Martin, Francis L

Publication type:

Article

Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 4, p. 224, doi. 10.1111/bcpt.13767

By:

Shilpa, Ganesan;
Lakshmi, Sreerenjini;
Jamsheena, Vellekkatt;
Lankalapalli, Ravi Shankar;
Prakash, Ved;
Anbumani, Sadasivam;
Priya, Sulochana

Publication type:

Article

Diindolylmethane Attenuates TGF β Mediated Human Lung Fibroblast Proliferation.

Published in:

FASEB Journal, 2013, v. 27, p. lb874, doi. 10.1096/fasebj.27.1_supplement.lb874

By:

Galam, Lakshmi;
Bandyopadhyay, Sayantani;
Martinez, Osvaldo;
Abuelenen, Toaa;
Castillo, Annie;
Parthasarathy, Prasanna;
Lagishetty, Venu;
Lockey, Richard;
Kolliputi, Narasaiah Kolliputi

Publication type:

Article

Air-stable Organobismuth(V) Bisperfluorooctanesulfonate as an Efficient Catalyst for the Synthesis of N-Containing Compounds.

Published in:

Advanced Synthesis & Catalysis, 2016, v. 358, n. 8, p. 1302, doi. 10.1002/adsc.201500998

By:

Wang, Penghui;
Wang, Jinying;
Au, Chak ‐ Tong;
Qiu, Renhua;
Xu, Xinhua;
Yin, Shuang ‐ Feng

Publication type:

Article

Role of BioResponse 3,3'-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience.

Published in:

Medical Principles & Practice, 2016, v. 25, p. 11, doi. 10.1159/000439307

By:

Yiwei Li;
Sarkar, Fazlul H.

Publication type:

Article

A Green Approach to the Production of Hybrid Diindolylmethane-Phenylboronic Acids via a 3MCR: Promising Antineoplasic Molecules.

Published in:

Journal of Chemistry, 2013, p. 1, doi. 10.1155/2013/531208

By:

arco Juarez, Mónica Z.;
Martínez, Joel Omar;
Noguez Cordova, Olivia;
Nicolás Vazquez, María Inés;
Ramírez-Apan, Teresa;
Pérez Flores, Javier;
Miranda Ruvalcaba, René;
Arroyo Razo, Gabriel Arturo

Publication type:

Article

3,3' Diindolylmethane Suppresses Vascular Smooth Muscle Cell Phenotypic Modulation and Inhibits Neointima Formation after Carotid Injury.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034957

By:

Hongjing Guan;
Lihua Zhu;
Mingyue Fu;
Da Yang;
Song Tian;
Yuanyuan Guo;
Changping Cui;
Lang Wang;
Hong Jiang

Publication type:

Article

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.

Published in:

Carcinogenesis, 2011, v. 32, n. 6, p. 836, doi. 10.1093/carcin/bgr040

By:

Yoon, Kyungsil;
Lee, Syng-Ook;
Cho, Sung-Dae;
Kim, Kyounghyun;
Khan, Shaheen;
Safe, Stephen

Publication type:

Article

Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription3 (STAT3).

Published in:: BMC Medicine, 2012, v. 10, n. 1, p. 9, doi. 10.1186/1741-7015-10-9
Publication type:: Article

3,3′-Diindolylmethane mitigates lipopolysaccharide-induced acute kidney injury in mice by inhibiting NOX-mediated oxidative stress and the apoptosis of renal tubular epithelial cells.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 6, p. 5115, doi. 10.3892/mmr.2019.10178

By:

He, Jin;
Huang, Tao;
Zhao, Lin

Publication type:

Article

3,3'-Diindolylmethane attenuates cardiomyocyte hypoxia by modulating autophagy in H9c2 cells.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 6, p. 9553, doi. 10.3892/mmr.2017.7788

By:

KAI LIANG;
WEN-HAO QIAN;
JING ZONG

Publication type:

Article

Pro-apoptotic and anti-proliferative effects of 3,3'-diindolylmethane in nasopharyngeal carcinoma cells via downregulation of telomerase activity.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3815, doi. 10.3892/mmr.2015.3836

By:

FEN LI;
YONG XU;
CHEN CHEN;
SHI-MING CHEN;
BO-KUI XIAO;
ZE-ZHANG TAO

Publication type:

Article

3,3'-Diindolylmethane attenuates cardiac H9c2 cell hypertrophy through 5'-adenosine monophosphate-activated protein kinase-α.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 1, p. 1247, doi. 10.3892/mmr.2015.3523

By:

JING ZONG;
QING-QING WU;
HENG ZHOU;
JIE-YU ZHANG;
YUAN YUAN;
ZHOU-YAN BIAN;
WEI DENG;
JIA DAI;
FANG-FANG LI;
MAN XU;
YI FANG;
QI-ZHU TANG

Publication type:

Article

BRCA1 mRNA levels following a 4-6-week intervention with oral 3,3′-diindolylmethane.

Published in:

British Journal of Cancer, 2014, v. 111, n. 7, p. 1269, doi. 10.1038/bjc.2014.391

By:

Kotsopoulos, J;
Akbari, M;
Narod, S A;
Zhang, S;
Llacuachaqui, M;
Sun, P;
Salmena, L;
Zeligs, M

Publication type:

Article