Works matching DNA topoisomerase II

Results: 2021

DNA 拓扑异构酶Ⅱ在ICR 小鼠神经干细胞中的表达及意义.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2022, v. 26, n. 1, p. 84, doi. 10.12307/2022.014

By:

孙孟军;
郭建美;
周更苏;
董泽飞;
郑春贵;
曹翠丽

Publication type:

Article

The rate of opening and closing of the DNA gate for topoisomerase II.

Published in:

Theory in Biosciences, 2013, v. 132, n. 1, p. 61, doi. 10.1007/s12064-012-0163-2

By:

Ding, Hui;
Lin, Hao;
Feng, Juan

Publication type:

Article

Immunohistochemical detection of DNA topoisomerase type II alpha and Ki-67 in adenoid cystic carcinoma and pleomorphic adenoma of the salivary gland.

Published in:

1999

By:

Hirabayashi, Susumu;
Hirabayashi, S

Publication type:

journal article

Inhibition of FGFR2-Signaling Attenuates a Homology-Mediated DNA Repair in GIST and Sensitizes Them to DNA-Topoisomerase II Inhibitors.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 352, doi. 10.3390/ijms21010352

By:

Sergei, Boichuk;
Pavel, Dunaev;
Aigul, Galembikova;
Firyuza, Bikinieva;
Ilmira, Nurgatina;
Ilshat, Mustafin;
Aida, Aukhadieva;
Refat, Kurtasanov;
Natalia, Andriutsa;
Elena, Shagimardanova;
Vera, Gorbunova

Publication type:

Article

Anti-DNA topoisomerase II α autoantibodies in Japanese patients with systemic sclerosis.

Published in:

Archives of Dermatological Research, 2005, v. 297, n. 4, p. 180, doi. 10.1007/s00403-005-0603-7

By:

Hayakawa, Ikuko;
Hasegawa, Minoru;
Takehara, Kazuhiko;
Sato, Shinichi

Publication type:

Article

Expression of DNA topoisomerase II-α: Clinical significance in laryngeal carcinoma.

Published in:

Oncology Letters, 2014, v. 8, n. 4, p. 1575, doi. 10.3892/ol.2014.2367

By:

YAN FENG;
HAILI ZHANG;
WEI GAO;
SHUXIN WEN;
HUI HUANGFU;
RUIFANG SUN;
WEI BAI;
BINQUAN WANG

Publication type:

Article

Design and Synthesis of Some New N-(Thiazol-2-yl) Benzamides of Quinoxaline as DNA Topoisomerase II Targeting Anticancer Agents and ADMET.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 7, p. 6319, doi. 10.1080/10406638.2022.2117208

By:

Bonakolluru, Yellaiah;
Nukala, Satheesh Kumar;
Dasari, Gouthami;
Badithapuram, Vinitha;
Manchal, Ravinder;
Bandari, Srinivas

Publication type:

Article

Virtual Screening and Molecular Dynamics Simulation Targeting the ATP Domain of African Swine Fever Virus Type II DNA Topoisomerase.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 5, p. 681, doi. 10.3390/v17050681

By:

Zhao, Rui;
Hou, Lezi;
Tesfagaber, Weldu;
Song, Linfei;
Zhang, Zhenjiang;
Li, Fang;
Bu, Zhigao;
Zhao, Dongming

Publication type:

Article

Therapy-related acute lymphoblastic leukaemia with MLL rearrangements following DNA topoisomerase II inhibitors, an increasing problem: report on two new cases and review of the literature since 1992.

Published in:

British Journal of Haematology, 2001, v. 114, n. 3, p. 539, doi. 10.1046/j.1365-2141.2001.03000.x

By:

Andersen, Mette Klarskov;
Christiansen, Debes H.;
Jensen, Bjarne Anker;
Ernst, Peter;
Hauge, Gunnar;
Pedersen-Bjergaard, Jens

Publication type:

Article

Oncogenetic Function and Prognostic Value of DNA Topoisomerase II Alpha in Human Malignances: A Pan-Cancer Analysis.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.856692

By:

Fulai Zhao;
Junli Chang;
Peng Zhao;
Wenyi Wang;
Xingyuan Sun;
Xiaoping Ma;
Mengchen Yin;
Yongjun Wang;
Yanping Yang

Publication type:

Article

Targeting DNA Homologous Repair Proficiency With Concomitant Topoisomerase II and c-Abl Inhibition.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.733700

By:

Siddiqui, Arafat;
Tumiati, Manuela;
Joko, Alia;
Sandholm, Jouko;
Roering, Pia;
Aakko, Sofia;
Vainionpää, Reetta;
Kaipio, Katja;
Huhtinen, Kaisa;
Kauppi, Liisa;
Tuomela, Johanna;
Hietanen, Sakari

Publication type:

Article

DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 5, p. 1, doi. 10.1371/journal.pntd.0002218

By:

Lin, Bo-Chi;
Su, Li-Hsin;
Weng, Shih-Che;
Pan, Yu-Jiao;
Chan, Nei-Li;
Li, Tsai-Kun;
Wang, Hsin-Chih;
Sun, Chin-Hung

Publication type:

Article

Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives alpha-lapachone and beta-lapachone.

Published in:

2001

By:

Krishnan, Preethi;
Bastow, Kenneth F.;
Krishnan, P;
Bastow, K F

Publication type:

journal article

New imidazole-2-thiones linked to acenaphythylenone as dual DNA intercalators and topoisomerase II inhibitors: structural optimization, docking, and apoptosis studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2311818

By:

Mohamed, Asmaa H.;
Alshammari, Mohammed B.;
Aly, Ashraf A.;
Sadek, Kamal U.;
Ahmad, Akil;
Aziz, Eman A.;
El-Yazbi, Amira F.;
El-Agroudy, Eman J.;
Abdelaziz, Marwa E.

Publication type:

Article

Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2171029

By:

Farouk, Faten;
Elmaaty, Ayman Abo;
Elkamhawy, Ahmed;
Tawfik, Haytham O.;
Alnajjar, Radwan;
Abourehab, Mohammed A. S.;
Saleh, Mohamed A.;
Eldehna, Wagdy M.;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Isobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response.

Published in:

Pharmacology Research & Perspectives, 2014, v. 2, n. 6, p. n/a, doi. 10.1002/prp2.70

By:

Mishra, Amartya;
Vinayagam, Jayaraman;
Saha, Sourav;
Chowdhury, Sayan;
Roychowdhury, Somenath;
Jaisankar, Parasuraman;
Majumder, Hemanta K.

Publication type:

Article

Broken proto-oncogenes AML1 and MLL leave the inherent chromosome territories in human lymphoid cells treated with DNA topoisomerase II poison etoposide.

Published in:

Biopolymers & Cell, 2015, p. 15

By:

Lomov, N. A.;
Rubtsov, M. A.;
Alexeyevsky, D. A.;
Vassetzky, Y. S.;
Razin, S. V.;
Iarovaia, O. V.

Publication type:

Article

Inhibition of p34[sup cdc2] dephosphorylation in DNA damage- and topoisomerase II inactivation-induced G2 arrests in HL-60 cells.

Published in:

British Journal of Haematology, 1999, v. 105, n. 3, p. 720, doi. 10.1046/j.1365-2141.1999.01400.x

By:

Sugimoto, Koichi;
Sasaki, Makoto;
Tamayose, Kenji;
Oshimi, Kazuo

Publication type:

Article

Structure and mechanism of DNA topoisomerase II.

Published in:

Nature, 1996, v. 379, n. 6562, p. 225, doi. 10.1038/379225a0

By:

Berger, James M.;
Gamblin, Steven J.

Publication type:

Article

DNA Interaction and Dual Topoisomerase I and II Inhibition Properties of the Anti-Tumor Drug Prodigiosin.

Published in:

Toxicological Sciences, 2005, v. 85, n. 2, p. 870, doi. 10.1093/toxsci/kfi149

By:

Montaner, Beatriz;
Castillo-Ávila, Wilmar;
Martinell, Marc;
Öllinger, Rupert;
Aymami, Joan;
Giralt, Ernest;
Pérez-Tomás, Ricardo

Publication type:

Article

Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.

Published in:

Oncogene, 2003, v. 22, n. 52, p. 8448, doi. 10.1038/sj.onc.1207052

By:

Whitmarsh, Ryan J.;
Saginario, Charles;
Zhuo, Ya;
Hilgenfeld, Eva;
Rappaport, Eric F.;
Megonigal, Maureen D.;
Carroll, Martin;
Liu, Mingli;
Osheroff, Neil;
Cheung, Nai-Kong V.;
Slater, Diana J.;
Ried, Thomas;
Knutsen, Turid;
Blair, Ian A.;
Felix, Carolyn A.

Publication type:

Article

Nanocurcumin: a novel antifilarial agent with DNA topoisomerase II inhibitory activity.

Published in:

Journal of Drug Targeting, 2014, v. 22, n. 5, p. 395, doi. 10.3109/1061186X.2013.869823

By:

Ali, Mohammad;
Afzal, Mohammad;
Abdul Nasim, Sekh;
Ahmad, Istaq

Publication type:

Article

A GyrB-GyrA fusion protein expressed in yeast cells is able to remove DNA supercoils but cannot substitute eukaryotic topoisomerase II.

Published in:

Genes to Cells, 2002, v. 7, n. 3, p. 249, doi. 10.1046/j.1365-2443.2002.00516.x

By:

Trigueros, Sonia;
Roca, Joaquim

Publication type:

Article

The Broken MLL Gene Is Frequently Located Outside the Inherent Chromosome Territory in Human Lymphoid Cells Treated with DNA Topoisomerase II Poison Etoposide.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075871

By:

Glukhov, Sergey I.;
Rubtsov, Mikhail A.;
Alexeyevsky, Daniil A.;
Alexeevski, Andrei V.;
Razin, Sergey V.;
Iarovaia, Olga V.

Publication type:

Article

CD117, CK20, TTF-1, and DNA topoisomerase II-α antigen expression in small cell tumors.

Published in:

Journal of Cutaneous Pathology, 2004, v. 31, n. 3, p. 254, doi. 10.1111/j.0303-6987.2003.00175.x

By:

Yang, David T.;
Holden, Joseph A.;
Florell, Scott R.

Publication type:

Article

DNA Topoisomerase II modulates acetyl-regulation of cohesin-mediated chromosome dynamics.

Published in:

Current Genetics, 2017, v. 63, n. 5, p. 923, doi. 10.1007/s00294-017-0691-x

By:

Lin, Su-Jiun;
O'Connell, Matthew

Publication type:

Article

DNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06158

By:

Thomson, Neil H.;
Santos, Sergio;
Mitchenall, Lesley A.;
Stuchinskaya, Tanya;
Taylor, James A.;
Maxwell, Anthony

Publication type:

Article

Inhibitory effect of coenzyme Q1 on eukaryotic DNA polymerase γ and DNA topoisomerase II activities on the growth of a human cancer cell line.

Published in:

Cancer Science, 2006, v. 97, n. 8, p. 716, doi. 10.1111/j.1349-7006.2006.00236.x

By:

Yonezawa, Yuko;
Kuriyama, Isoko;
Fukuoh, Atsushi;
Muta, Tsuyoshi;
Kang, Dongchon;
Takemura, Masaharu;
Kato, Ikuo;
Yoshida, Hiromi;
Mizushina, Yoshiyuki

Publication type:

Article

Autoantibodies to DNA topoisomerase II in juvenile rheumatoid arthritis.

Published in:

Clinical & Experimental Immunology, 1991, v. 84, n. 2, p. 245

By:

Zuklys, K. L.;
Szer, I. S.;
Szer, W.

Publication type:

Article

Role of recombinational repair in sensitivity to an antitumour agent that inhibits bacteriophage T4 type II DNA topoisomerase.

Published in:

Molecular Microbiology, 1996, v. 20, n. 6, p. 1145, doi. 10.1111/j.1365-2958.1996.tb02635.x

By:

Neece, Sue H.;
Carles-Kinch, Kelly;
Tomso, Daniel J.;
Kreuzer, Kenneth N.

Publication type:

Article

DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 5, p. 1, doi. 10.1371/journal.pntd.0002218

By:

Lin, Bo-Chi;
Su, Li-Hsin;
Weng, Shih-Che;
Pan, Yu-Jiao;
Chan, Nei-Li;
Li, Tsai-Kun;
Wang, Hsin-Chih;
Sun, Chin-Hung

Publication type:

Article

Histone deacetylase interacts directly with DNA topoisomerase II.

Published in:

Nature Genetics, 2000, v. 26, n. 3, p. 349, doi. 10.1038/81671

By:

Tsai, Shih-Chang;
Valkov, Nikola;
Yang, Wen-Ming;
Gump, Jana;
Sullivan, Daniel;
Seto, Edward

Publication type:

Article

Evidence for a Role of Vertebrate Rad52 in the Repair of Topoisomerase II–Mediated DNA Damage.

Published in:

DNA & Cell Biology, 2005, v. 24, n. 6, p. 388, doi. 10.1089/dna.2005.24.388

By:

Adachi, Noritaka;
Iiizumi, Susumu;
Koyama, Hideki

Publication type:

Article

Direct Monitoring of the Strand Passage Reaction of DNA Topoisomerase II Triggers Checkpoint Activation.

Published in:

PLoS Genetics, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pgen.1003832

By:

Furniss, Katherine L.;
Tsai, Hung-Ji;
Byl, Jo Ann W.;
Lane, Andrew B.;
Vas, Amit C.;
Hsu, Wei-Shan;
Osheroff, Neil;
Clarke, Duncan J.

Publication type:

Article

Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 1, p. 25, doi. 10.1007/s00280-014-2469-x

By:

Chen, Ying;
Lukka, Pradeep;
Joseph, Wayne;
Finlay, Graeme;
Paxton, James;
McKeage, Mark;
Baguley, Bruce

Publication type:

Article

Structure-activity study of the interaction of bioreductive benzoquinone alkylating agents with DNA topoisomerase II.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 2, p. 221, doi. 10.1007/s00280-005-0040-5

By:

Hasinoff, Brian B.;
Xing Wu;
Begleiter, Asher;
Guziec, Lynn J.;
Guziec Jr., Frank;
Giorgianni, Angela;
Shaohua Yang;
Yu Jiang;
Yalowich, Jack C.

Publication type:

Article

Cytotoxicity and molecular docking to DNA topoisomerase II of chalcone flavokawain B isolated from Kaempferia elegans rhizomes.

Published in:

ScienceAsia, 2023, v. 49, n. 3, p. 421, doi. 10.2306/scienceasia1513-1874.2023.036

By:

Savaspun, Kongdech;
Boonchaisri, Siriwat;
Chaisuriya, Papada;
Srisomsap, Chantragan;
Svasti, Jisnuson;
Ardkhean, Ruchuta;
Phanumartwiwath, Anuchit;
Sam-ang, Pornpat

Publication type:

Article

Virtual Screening of an Anthracyclines Combinatorial Library Against DNA Topoisomerase II, Alpha Isozyme.

Published in:: 2010
Publication type:: Abstract

Design and in silico Prediction of New Methylenedioxyphenyl Derivatives as DNA Topoisomerase II Inhibitors.

Published in:

International Journal of Pharmaceutical Investigation, 2023, v. 13, n. 3, p. 548, doi. 10.5530/ijpi.13.3.068

By:

Rathore, Swati;
Reddemma, Maadhu;
Rai, Neha;
Tiwari, Richa Tripathy;
Begum, Shaheen;
Patil, Shailendra;
Patil, Asmita Gajbhiye

Publication type:

Article

Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.

Published in:

Genes, 2019, v. 10, n. 11, p. 868, doi. 10.3390/genes10110868

By:

Morimoto, Suguru;
Tsuda, Masataka;
Bunch, Heeyoun;
Sasanuma, Hiroyuki;
Austin, Caroline;
Takeda, Shunichi

Publication type:

Article

Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility.

Published in:

Genes, 2019, v. 10, n. 10, p. 791, doi. 10.3390/genes10100791

By:

Atkin, Naomi D.;
Raimer, Heather M.;
Wang, Yuh-Hwa

Publication type:

Article

Evaluation of Interactions of Selected Olivacine Derivatives with DNA and Topoisomerase II.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8492, doi. 10.3390/ijms22168492

By:

Tylińska, Beata;
Dobosz, Agnieszka;
Spychała, Jan;
Cwynar-Zając, Łucja;
Czyżnikowska, Żaneta;
Kuźniarski, Amadeusz;
Gębarowski, Tomasz

Publication type:

Article

Topoisomerase II–DNA complexes trapped by ICRF-193 perturb chromatin structure.

Published in:

2005

By:

Germe, Thomas;
Hyrien, Olivier

Publication type:

Report

Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.68918

By:

Choppakatla, Pavan;
Dekker, Bastiaan;
Cutts, Erin E.;
Vannini, Alessandro;
Dekker, Job;
Hironori Funabiki

Publication type:

Article

Fluoroquinolone Resistance Mutations in the DNA Topoisomerase II Genes of Viridans Group Streptococci Clinical Isolates.

Published in:

Drugs, 1999, v. 58, n. 6, p. 125, doi. 10.2165/00003495-199958002-00029

By:

Balas, D.;
González, I.;
Georgiou, M.;
Alcaide, F.;
Liñares, J.;
de La Campa, A.G.

Publication type:

Article

Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.

Published in:

BMC Pharmacology, 2004, v. 4, p. 31, doi. 10.1186/1471-2210-4-31

By:

Jensen, Lars H.;
Dejligbjerg, Marielle;
Hansen, Lasse T.;
Grauslund, Morten;
Jensen, Peter B.;
Sehested, Maxwell

Publication type:

Article

DNA topoisomerase II as a target for cancer chemotherapy.

Published in:

2002

By:

Walker, Jerrylaine V.;
Nitiss, John L.

Publication type:

journal article

Activity of M3814, an Oral DNA-PK Inhibitor, In Combination with Topoisomerase II Inhibitors in Ovarian Cancer Models.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-54796-6

By:

Wise, Hannah C.;
Iyer, Gopakumar V.;
Moore, Kathleen;
Temkin, Sarah M.;
Gordon, Sarah;
Aghajanian, Carol;
Grisham, Rachel N.

Publication type:

Article

Untangling the role of DNA topoisomerase II in mitotic chromosome structure and function.

Published in:

BioEssays, 1997, v. 19, n. 2, p. 97, doi. 10.1002/bies.950190203

By:

Warburton, Peter E.;
Earnshaw, William C.

Publication type:

Article

Emodin Triggers DNA Double-Strand Breaks by Stabilizing Topoisomerase II-DNA Cleavage Complexes and by Inhibiting ATP Hydrolysis of Topoisomerase II.

Published in:

Toxicological Sciences, 2010, v. 118, n. 2, p. 435, doi. 10.1093/toxsci/kfq282

By:

Li, Yan;
Luan, Yang;
Qi, Xinming;
Li, Ming;
Gong, Likun;
Xue, Xiang;
Wu, Xiongfei;
Wu, Yuanfeng;
Chen, Min;
Xing, Guozhen;
Yao, Jun;
Ren, Jin

Publication type:

Article