Works matching DNA topoisomerase I
Results: 1600
Inhibitory Activities of Helichrysum Taxa on Mammalian Type I DNA Topoisomerase.
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- Pharmaceutical Biology, 2006, v. 44, n. 3, p. 189, doi. 10.1080/13880200600685972
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Antileishmanial activity evaluation of bis-lawsone analogs and DNA topoisomerase-I inhibition studies.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2014, v. 29, n. 2, p. 185, doi. 10.3109/14756366.2013.765413
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Boldine-Derived Alkaloids Inhibit the Activity of DNA Topoisomerase I and Growth of Mycobacterium tuberculosis.
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- Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.01659
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Potential Inhibitors of Monkeypox Virus Revealed by Molecular Modeling Approach to Viral DNA Topoisomerase I.
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- Molecules, 2023, v. 28, n. 3, p. 1444, doi. 10.3390/molecules28031444
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Pharmacokinetics, tissue distribution, and metabolism of novel DNA topoisomerase I inhibitor yuanhuacine in rabbit.
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- Xenobiotica, 2009, v. 39, n. 3, p. 273, doi. 10.1080/00498250802715987
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Seconeolitsine, the Novel Inhibitor of DNA Topoisomerase I, Protects against Invasive Pneumococcal Disease Caused by Fluoroquinolone-Resistant Strains.
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- Antibiotics (2079-6382), 2021, v. 10, n. 5, p. 573, doi. 10.3390/antibiotics10050573
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Synthesis, characterization, and investigation of singlet oxygen, DNA interaction, and topoisomerase I inhibition properties of novel zinc(II) phthalocyanine.
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- Turkish Journal of Chemistry, 2019, v. 43, n. 6, p. 1646, doi. 10.3906/kim-1909-32
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Cytotoxic activity of 4′-hydroxychalcone derivatives against Jurkat cells and their effects on mammalian DNA topoisomerase I.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 3, p. 804, doi. 10.1080/14756360802399126
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Iridoids as DNA topoisomerase I poisons.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2005, v. 20, n. 4, p. 389, doi. 10.1080/14756360500141879
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Regulation of gene expression, cellular localization, and in vivo function of Caenorhabditis elegans DNA topoisomerase I.
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- Genes to Cells, 2001, v. 6, n. 4, p. 303, doi. 10.1046/j.1365-2443.2001.00423.x
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Three-dimensional structure of the 67k N-terminal fragment of E. coli DNA topoisomerase I.
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- Nature, 1994, v. 367, n. 6459, p. 138, doi. 10.1038/367138a0
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Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex.
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- Cell Death & Differentiation, 2007, v. 14, n. 2, p. 358, doi. 10.1038/sj.cdd.4402002
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Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.
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- Nature, 1996, v. 381, n. 6577, p. 80, doi. 10.1038/381080a0
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Raman Spectroscopy of Topotecan, an Inhibitor of DNA Topoisomerase I.
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- Optics & Spectroscopy, 2002, v. 93, n. 4, p. 493, doi. 10.1134/1.1517071
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Why Should DNA Topoisomerase I Have a Scaffold Activity?
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- Biology (2079-7737), 2021, v. 10, n. 3, p. 190, doi. 10.3390/biology10030190
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Genetic Analysis of Saccharomyces cerevisiae H2A Serine 129 Mutant Suggests a Functional Relationship Between H2A and the Sister-Chromatid Cohesion Partners Csm3—Tof1 for the Repair of Topoisomerase I-Induced DNA Damage.
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- Genetics, 2006, v. 172, n. 1, p. 67, doi. 10.1534/genetics.105.046128
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Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase.
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- PLoS Genetics, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.pgen.1006754
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Effects of the Cdc2-like kinase-family and DNA topoisomerase I on the alternative splicing of eNOS in TNF-α-stimulated human endothelial cells.
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- Biological Chemistry, 2008, v. 389, n. 10, p. 1333, doi. 10.1515/BC.2008.152
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DNA Interaction and Dual Topoisomerase I and II Inhibition Properties of the Anti-Tumor Drug Prodigiosin.
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- Toxicological Sciences, 2005, v. 85, n. 2, p. 870, doi. 10.1093/toxsci/kfi149
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Corrigendum: 7-Ethyl-10-Hydroxycamptothecin, A DNA Topoisomerase I Inhibitor, Performs BRD4 Inhibitory Activity and Inhibits Human Leukemic Cell Growth.
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- 2021
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- Correction Notice
Structural and Dynamical Effects Induced by the Anticancer Drug Topotecan on the Human Topoisomerase I -- DNA Complex.
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- PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0010934
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Conformational changes in E. coli DNA topoisomerase I.
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- Nature Structural Biology, 1999, v. 6, n. 10, p. 918
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Protein?nucleotide interactions in E. coli DNA topoisomerase I.
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- Nature Structural Biology, 1999, v. 6, n. 10, p. 961
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Redox Modulation of the Activity of DNA Topoisomerase I from Carrot (Daucus carota) Mitochondria.
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- Doklady Biochemistry & Biophysics, 2001, v. 377, n. 1-6, p. 82, doi. 10.1023/A:1011523522080
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Elevations of DNA Topoisomerase I in Invasive Carcinoma of the Breast.
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- Breast Journal, 2001, v. 7, n. 3, p. 176, doi. 10.1046/j.1524-4741.2001.007003176.x
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Physical and functional interactions between 3-methyladenine DNA glycosylase and topoisomerase I in mycobacteria.
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- Biochemistry (00062979), 2012, v. 77, n. 4, p. 378, doi. 10.1134/S0006297912040098
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Activity of intoplicine (RP60475), a new DNA topoisomerase I and II inhibitor, against human...
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- JNCI: Journal of the National Cancer Institute, 1994, v. 86, n. 1, p. 30, doi. 10.1093/jnci/86.1.30
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DNA topoisomerase I and IIα expression in penile carcinomas: assessing potential tumour chemosensitivity.
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- BJU International, 2008, v. 102, n. 8, p. 1040, doi. 10.1111/j.1464-410X.2008.07698.x
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Flavonolignan Conjugates as DNA-binding Ligands and Topoisomerase I Inhibitors: Electrochemical and Electrophoretic Approaches.
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- Electroanalysis, 2016, v. 28, n. 11, p. 2866, doi. 10.1002/elan.201600146
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DNA topoisomerase I is involved in both repression and activation of transcription.
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- Nature, 1993, v. 365, n. 6443, p. 227, doi. 10.1038/365227a0
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New designed DNA light switch Ruthenium complexes as DNA photocleavers and Topoisomerase I inhibitors.
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- Applied Organometallic Chemistry, 2018, v. 32, n. 4, p. 1, doi. 10.1002/aoc.4231
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Development of DNA delivery system using Pseudomonas exotoxin A and a DNA binding region of human DNA topoisomerase I.
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- Applied Microbiology & Biotechnology, 2000, v. 53, n. 5, p. 558, doi. 10.1007/s002530051657
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Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2014, v. 33, n. 1, p. 1, doi. 10.1186/s13046-014-0071-z
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Antibacterial activity of a DNA topoisomerase I inhibitor versus fluoroquinolones in Streptococcus pneumoniae.
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- PLoS ONE, 2020, v. 15, n. 11, p. N.PAG, doi. 10.1371/journal.pone.0241780
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The E3 ligase Topors induces the accumulation of polysumoylated forms of DNA topoisomerase I in vitro and in vivo
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- FEBS Letters, 2007, v. 581, n. 28, p. 5418, doi. 10.1016/j.febslet.2007.10.040
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ANTHOCYANIN INTERACTIONS WITH DNA: INTERCALATION, TOPOISOMERASE I INHIBITION AND OXIDATIVE REACTIONS.
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- Journal of Food Biochemistry, 2008, v. 32, n. 5, p. 576, doi. 10.1111/j.1745-4514.2008.00181.x
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Isolation of mutants of Saccharomyces cerevisiae requiring DNA topoisomerase I.
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- Genetics, 1995, v. 141, n. 2, p. 465, doi. 10.1093/genetics/141.2.465
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- Article
Interaction of Topotecan, DNA Topoisomerase I Inhibitor, with Double-Stranded Polydeoxyribonucleotides. 1. Topotecan Dimerization in Solution.
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- Molecular Biology, 2001, v. 35, n. 3, p. 365, doi. 10.1023/A:1010422711817
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Interaction of Topotecan, DNA Topoisomerase I Inhibitor, with Double-Stranded Polydeoxyribonucleotides. 2. Formation of Topotecan–DNA Complex Containing Several DNA Molecules.
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- Molecular Biology, 2001, v. 35, n. 3, p. 374, doi. 10.1023/A:1010474728655
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The interference of piperidinopropionaphthone hydrochloride in mammalian type I and type II DNA topoisomerase reactions.
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- Marmara Pharmaceutical Journal, 2015, v. 19, n. 2, p. 82, doi. 10.12991/mpj.2015199638
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The distinctive cellular responses to DNA strand breaks caused by a DNA topoisomerase I poison in conjunction with DNA replication and RNA transcription.
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- Genes & Genetic Systems, 2015, v. 90, n. 4, p. 187, doi. 10.1266/ggs.15-00023
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Genome-wide proximity between RNA polymerase and DNA topoisomerase I supports transcription in Streptococcus pneumoniae.
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- PLoS Genetics, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.pgen.1009542
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The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I.
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- BMC Biochemistry, 2002, v. 3, p. 1
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Multiple gene copy number increases total protein expression and enzyme activity of DNA topoisomerase I in Pichia pastoris.
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- World Academy of Sciences Journal, 2022, v. 4, n. 5, p. 1, doi. 10.3892/wasj.2022.167
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International consensus on antinuclear antibody patterns: definition of the AC-29 pattern associated with antibodies to DNA topoisomerase I.
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- Clinical Chemistry & Laboratory Medicine, 2018, v. 56, n. 10, p. 1783, doi. 10.1515/cclm-2018-0188
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DNA-Binding and Topoisomerase-I-Suppressing Activities of Novel Vanadium Compound Van-7.
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- Bioinorganic Chemistry & Applications, 2012, p. 1, doi. 10.1155/2012/756374
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DB-1310, an ADC comprised of a novel anti-HER3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of HER3-positive solid tumors.
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- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05133-7
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DNA topoisomerases I and II in human mature sperm cells: characterization and unique properties.
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- Human Reproduction, 2007, v. 22, n. 8, p. 2183, doi. 10.1093/humrep/dem170
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Comparative analysis of nuclear and mitochondrial DNA topoisomerase I from Zea mays.
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- Molecular Biology, 2008, v. 42, n. 1, p. 79, doi. 10.1134/S0026893308010111
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Computer Analysis of Conformational and Physicochemical Properties of Nucleotide Sequences Cleavable by DNA Topoisomerase I.
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- Molecular Biology, 2005, v. 39, n. 3, p. 430, doi. 10.1007/s11008-005-0058-0
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- Article