Works matching DE "ZYMOGENS"

Results: 199

Highly Conserved Arg Residue of ERFNIN Motif of Pro-Domain is Important for pH-Induced Zymogen Activation Process in Cysteine Cathepsins K and L.

Published in:

Cell Biochemistry & Biophysics, 2018, v. 76, n. 1/2, p. 219, doi. 10.1007/s12013-017-0838-x

By:

Aich, Pulakesh;
Biswas, Sampa

Publication type:

Article

Ileal Inflammation May Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease.

Published in:

Clinical & Developmental Immunology, 2012, p. 1, doi. 10.1155/2012/640835

By:

Pavlidis, Polychronis;
Romanidou, Ourania;
Roggenbuck, Dirk;
Mytilinaiou, Maria G.;
Al-Sulttan, Faris;
Liaskos, Christos;
Smyk, Daniel S.;
Koutsoumpas, Andreas L.;
Rigopoulou, Eirini I.;
Conrad, Karsten;
Forbes, Alastair;
Bogdanos, Dimitrios P.

Publication type:

Article

Spautin-1 Ameliorates Acute Pancreatitis via inhibiting impaired Autophagy and Alleviating Calcium Overload.

Published in:

Molecular Medicine, 2016, v. 22, n. 1, p. 643, doi. 10.2119/molmed.2016.00034

By:

Xiao, Juan;
Feng, Xueping;
Huang, Xiao-Ying;
Huang, Zhongshi;
Huang, Yanqiang;
Li, Chaogan;
Li, Genliang;
Nong, Song;
Wu, Ruoshi;
Huang, Yongzhi;
Long, Xi-Dai

Publication type:

Article

Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload.

Published in:

Molecular Medicine, 2016, v. 22, p. 643, doi. 10.2119/molmed.2016.00034

By:

Juan Xiao;
Xueping Feng;
Xiao-Ying Huang;
Zhongshi Huang;
Yanqiang Huang;
Chaogan Li;
Genliang Li;
Song Nong;
Ruoshi Wu;
Yongzhi Huang;
Xi-Dai Long

Publication type:

Article

Adjuvant-free schistosome cathepsin L3 is an efficacious schistosomiasis vaccine–comment on Huang et al.: Characteristics and function of cathepsin L3 from Schistosoma japonicum.

Published in:

2020

By:

Tallima, Hatem;
El Ridi, Rashika

Publication type:

Letter

Metabolite Transformation and Enzyme Activities of Hainan Vanilla Beans During Curing to Improve Flavor Formation.

Published in:

Molecules, 2019, v. 24, n. 15, p. 2781, doi. 10.3390/molecules24152781

By:

Cai, Yingying;
Gu, Fenglin;
Hong, Yinghua;
Chen, Yonggan;
Xu, Fei;
An, Kejing;
Simal-Gandara, Jesus

Publication type:

Article

Proteolytic Systems in Milk: Perspectives on the Evolutionary Function within the Mammary Gland and the Infant.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2015, v. 20, n. 3/4, p. 133, doi. 10.1007/s10911-015-9334-3

By:

Dallas, David;
Murray, Niamh;
Gan, Junai

Publication type:

Article

Lesch-Nyhan disease: I. Construction of expression vectors for hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme and amyloid precursor protein (APP).

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2020, v. 39, n. 6, p. 905, doi. 10.1080/15257770.2020.1714653

By:

Nguyen, Khue Vu;
Naviaux, Robert K.;
Nyhan, William L.

Publication type:

Article

A Corin Variant Identified in Hypertensive Patients That Alters Cytoplasmic Tail and Reduces Cell Surface Expression and Activity.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07378

By:

Yue Zhang;
Hui Li;
Jianping Zhou;
Aili Wang;
Junhua Yang;
Can Wang;
Meng Liu;
Tiantian Zhou;
Li Zhu;
Yonghong Zhang;
Ningzheng Dong;
Qingyu Wu

Publication type:

Article

Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52214-8

By:

Elwakiel, Ahmed;
Gupta, Dheerendra;
Rana, Rajiv;
Manoharan, Jayakumar;
Al-Dabet, Moh'd Mohanad;
Ambreen, Saira;
Fatima, Sameen;
Zimmermann, Silke;
Mathew, Akash;
Li, Zhiyang;
Singh, Kunal;
Gupta, Anubhuti;
Pal, Surinder;
Sulaj, Alba;
Kopf, Stefan;
Schwab, Constantin;
Baber, Ronny;
Geffers, Robert;
Götze, Tom;
Alo, Bekas

Publication type:

Article

SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50068-8

By:

Hendrix, Sebastian;
Dartigue, Vincent;
Hall, Hailee;
Bawaria, Shrankhla;
Kingma, Jenina;
Bajaj, Bilkish;
Zelcer, Noam;
Kober, Daniel L.

Publication type:

Article

Site directed mutagenesis is helping of the central domain of streptokinase in substrate plasminogen.

Published in:

International Journal of Pharmacy & Life Sciences, 2017, v. 8, n. 6, p. 5521

By:

Singh, Pushpendra;
Saxena, Arati;
Yadav, Mahavir

Publication type:

Article

Zymophagy: Selective Autophagy of Secretory Granules.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/396705

By:

Vaccaro, Maria I.

Publication type:

Article

Activity and post-prandial regulation of digestive enzyme activity along the Pacific hagfish (Eptatretus stoutii) alimentary canal.

Published in:

PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215027

By:

Weinrauch, Alyssa M.;
Schaefer, Christina M.;
Goss, Greg G.

Publication type:

Article

Safety, Tolerability, and Pharmacokinetics of the β‐Site Amyloid Precursor Protein‐Cleaving Enzyme 1 Inhibitor Verubecestat (MK‐8931) in Healthy Elderly Male and Female Subjects.

Published in:

CTS: Clinical & Translational Science, 2019, v. 12, n. 5, p. 545, doi. 10.1111/cts.12645

By:

Forman, Mark;
Palcza, John;
Tseng, Jack;
Stone, Julie A.;
Walker, Brittany;
Swearingen, Dennis;
Troyer, Matthew D.;
Dockendorf, Marissa F.

Publication type:

Article

Protein C zymogen in severe sepsis: a double-blinded, placebo-controlled, randomized study.

Published in:

2016

By:

Pappalardo, Federico;
Crivellari, Martina;
Di Prima, Ambra;
Agracheva, Nataliya;
Celinska-Spodar, Malgorzata;
Lembo, Rosalba;
Taddeo, Daiana;
Landoni, Giovanni;
Zangrillo, Alberto;
Di Prima, Ambra L

Publication type:

journal article

Estimation bias resulting from sparse data.

Published in:

2016

By:

Zhang, Zhongheng;
Ren, Bo

Publication type:

Letter

Gαi3in Pancreatic Zymogen Granules Participates in Vesicular Fusion1.

Published in:

Journal of Biochemistry, 2002, v. 131, n. 6, p. 815, doi. 10.1093/oxfordjournals.jbchem.a003170

By:

Sattar, Akm A.;
Boinpally, Ramesh;
Stromer, Marvin H.;
Jena, Bhanu P.

Publication type:

Article

Activation of Caspase-3, Proteolytic Cleavage of DFF and No Oligonucleosomal DNA Fragmentation in Apoptotic Molt-4 Cells.

Published in:

Journal of Biochemistry, 2002, v. 131, n. 3, p. 469, doi. 10.1093/oxfordjournals.jbchem.a003123

By:

Iguchi, Kazuhiro;
Hirano, Kazuyuki;
Ishida, Ryoji

Publication type:

Article

Domain Evolution of Vertebrate Blood Coagulation Cascade Proteins.

Published in:

Journal of Molecular Evolution, 2022, v. 90, n. 6, p. 418, doi. 10.1007/s00239-022-10071-3

By:

Coban, Abdulbaki;
Bornberg-Bauer, Erich;
Kemena, Carsten

Publication type:

Article

Degradation-Suppressed Cocoonase for Investigating the Propeptide-Mediated Activation Mechanism.

Published in:

Molecules, 2022, v. 27, n. 22, p. 8063, doi. 10.3390/molecules27228063

By:

Sakata, Nana;
Ogata, Ayumi;
Takegawa, Mai;
Murakami, Yuri;
Nishimura, Misaki;
Miyazawa, Mitsuhiro;
Hagiwara, Teruki;
Shimamoto, Shigeru;
Hidaka, Yuji

Publication type:

Article

Insights into the regulation of the matriptaseprostasin proteolytic system.

Published in:

Biochemical Journal, 2020, v. 477, n. 22, p. 4349, doi. 10.1042/BCJ20200630

By:

Holt-Danborg, Lasse;
Skovbjerg, Signe;
Goderum, Kristian W.;
Nonboe, Annika W.;
Stankevic, Evelina;
Frost, Ásdis K.;
Vitved, Lars;
Jensen, Jan K.;
Vogel, Lotte K.

Publication type:

Article

Inhibition of an active zymogen protease: the zymogen form of matriptase is regulated by HAI-1 and HAI-2.

Published in:

Biochemical Journal, 2020, v. 477, n. 9, p. 1779, doi. 10.1042/BCJ20200182

By:

Skovbjerg, Signe;
Holt-Danborg, Lasse;
Nonboe, Annika W.;
Zebin Hong;
Frost, Ásdís K.;
Schar, Christine R.;
Thomas, Cecilia C.;
Vitved, Lars;
Jensen, Jan K.;
Vogel, Lotte K.

Publication type:

Article

Lectin ZG16p inhibits proliferation of human colorectal cancer cells via its carbohydrate-binding sites.

Published in:

Glycobiology, 2018, v. 28, n. 1, p. 21, doi. 10.1093/glycob/cwx088

By:

Akiko Mito;
Yukiko Nakano;
Takako Saitoh;
Gouraud, Sabine S. S.;
Yoshiki Yamaguchi;
Toshiro Sato;
Nobuo Sasaki;
Kyoko Kojima-Aikawa

Publication type:

Article

ZG16p, an animal homolog of β-prism fold plant lectins, interacts with heparan sulfate proteoglycans in pancreatic zymogen granules.

Published in:

Glycobiology, 2012, v. 22, n. 2, p. 258, doi. 10.1093/glycob/cwr145

By:

Kumazawa-Inoue, Kaori;
Mimura, Tomoko;
Hosokawa-Tamiya, Sachiko;
Nakano, Yukiko;
Dohmae, Naoshi;
Kinoshita-Toyoda, Akiko;
Toyoda, Hidenao;
Kojima-Aikawa, Kyoko

Publication type:

Article

Human ZG16p recognizes pathogenic fungi through non-self polyvalent mannose in the digestive system.

Published in:

Glycobiology, 2012, v. 22, n. 2, p. 210, doi. 10.1093/glycob/cwr130

By:

Tateno, Hiroaki;
Yabe, Rikio;
Sato, Takashi;
Shibazaki, Azusa;
Shikanai, Toshihide;
Gonoi, Tohru;
Narimatsu, Hisashi;
Hirabayashi, Jun

Publication type:

Article

Evolocumab in treatment of acute pancreatitis induced by hypertriglyceridemia.

Published in:

Journal of Drug Delivery & Therapeutics, 2019, v. 9, n. 6, p. 135, doi. 10.22270/jddt.v9i6.3717

By:

El-Reshaid, Kamel;
Al-Bader, Shaikha;
Markova, Zhaneta

Publication type:

Article

Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.83725

By:

Akuma, Daniel C.;
Wodzanowski, Kimberly A.;
Wertman, Ronit Schwartz;
Exconde, Patrick M.;
Vázquez Marrero, Víctor R.;
Odunze, Chukwuma E.;
Grubaugh, Daniel;
Shin, Sunny;
Taabazuing, Cornelius;
Brodsky, Igor E.

Publication type:

Article

Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases.

Published in:

Frontiers in Cellular & Infection Microbiology, 2017, v. 7, p. 1, doi. 10.3389/fcimb.2017.00166

By:

Pietrocola, Giampiero;
Nobile, Giulia;
Rindi, Simonetta;
Speziale, Pietro

Publication type:

Article

Crystal structures of human procathepsin H.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0200374

By:

Hao, Yue;
Purtha, Whitney;
Cortesio, Christa;
Rui, Huan;
Gu, Yan;
Chen, Hao;
Sickmier, E. Allen;
Manzanillo, Paolo;
Huang, Xin

Publication type:

Article

Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0197362

By:

Alahmari, A. A.;
Sreekumar, B.;
Patel, V.;
Ashat, M.;
Alexandre, M.;
Uduman, A. K.;
Akinbiyi, E. O.;
Ceplenski, A.;
Shugrue, C. A.;
Kolodecik, T. R.;
Tashkandi, N.;
Messenger, S. W.;
Groblewski, G. E.;
Gorelick, F. S.;
Thrower, E. C.

Publication type:

Article

Molecular characterization of EcCLP1, a new putative cathepsin L protease from Echinococcus canadensis.

Published in:

Parasite (1252607X), 2024, v. 31, p. 1, doi. 10.1051/parasite/2024036

By:

Naidich, Ariel;
Gutierrez, Ariana M.;
Camicia, Federico

Publication type:

Article

Proprotein Convertases Subtilisin/ Kexin Type 9, an enzyme turned escort protein: Hepatic and extra hepatic functions (第9型前蛋白转换酶-枯草溶菌素/蛋白酶K，一种酶转变的护送蛋白：在肝脏与肝外的功能)

Published in:

Journal of Diabetes, 2013, v. 5, n. 4, p. 391, doi. 10.1111/1753-0407.12064

By:

Mbikay, Majambu;
Mayne, Janice;
Chrétien, Michel

Publication type:

Article

Neuroserpin Differentiates Between Forms of Tissue Type Plasminogen Activator via pH Dependent Deacylation.

Published in:

Frontiers in Cellular Neuroscience, 2016, p. 1, doi. 10.3389/fncel.2016.00154

By:

Carlson, Karen-Sue B.;
Lan Nguyen;
Schwartz, Kat;
Lawrence, Daniel A.;
Schwartz, Bradford S.

Publication type:

Article

Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation.

Published in:

FASEB Journal, 2013, v. 27, n. 7, p. 2818, doi. 10.1096/fj.12-224279

By:

Yi-Hung Wu;
Hsiao-Fan Lo;
Sih-Han Chen;
Hungwen Chen

Publication type:

Article

Soluble expression of recombinant midgut zymogen (native propeptide) proteases from the Aedes aegypti Mosquito Utilizing E. coli as a host.

Published in:

BMC Biochemistry, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12858-018-0101-0

By:

Nguyen, James T.;
Fong, Jonathan;
Fong, Daniel;
Fong, Timothy;
Lucero, Rachael M.;
Gallimore, Jamie M.;
Burata, Olive E.;
Parungao, Kamille;
Rascón, Alberto A.

Publication type:

Article

Curcumin inhibits BACE1 expression through the interaction between ERβ and NFκB signaling pathway in SH-SY5Y cells.

Published in:

Molecular & Cellular Biochemistry, 2020, v. 463, n. 1/2, p. 161, doi. 10.1007/s11010-019-03638-0

By:

Huang, Pan;
Zheng, Nan;
Zhou, Hai-bing;
Huang, Jian

Publication type:

Article

Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis.

Published in:

Journal of Molecular Medicine, 2020, v. 98, n. 4, p. 585, doi. 10.1007/s00109-020-01889-9

By:

Almholt, Kasper;
Wang, Jishu;
Pass, Jesper;
Røder, Gustav;
Padkjær, Søren B.;
Hebsgaard, Josephine B.;
Xia, Wenjuan;
Yang, Li;
Forsell, Johan;
Breinholt, Vibeke M.;
Thygesen, Peter;
Agersø, Henrik;
Loftager, Mette;
Usher, Pernille A.

Publication type:

Article

Molecular basis of the digestive functionality in developing Persian sturgeon (Acipenser persicus) larvae: additional clues for its phylogenetic status.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2019, v. 189, n. 3/4, p. 367, doi. 10.1007/s00360-019-01215-x

By:

Gilannejad, Neda;
Paykan Heyrati, Fatemeh;
Dorafshan, Salar;
Martos-Sitcha, Juan Antonio;
Yúfera, Manuel;
Martínez-Rodríguez, Gonzalo

Publication type:

Article

Proteoglycans support proper granule formation in pancreatic acinar cells.

Published in:

Histochemistry & Cell Biology, 2015, v. 144, n. 4, p. 331, doi. 10.1007/s00418-015-1339-x

By:

Aroso, Miguel;
Agricola, Brigitte;
Hacker, Christian;
Schrader, Michael

Publication type:

Article

Glycosylation of matrix metalloproteases and tissue inhibitors: present state, challenges and opportunities.

Published in:

Biochemical Journal, 2016, v. 473, n. 11, p. 1471, doi. 10.1042/BJ20151154

By:

Boon, Lise;
Ugarte-Berzal, Estefania;
Vandooren, Jennifer;
Opdenakker, Ghislain

Publication type:

Article

Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1.

Published in:

Biochemical Journal, 2015, v. 465, n. 2, p. 259, doi. 10.1042/BJ20140418

By:

Vandooren, Jennifer;
Born, Benjamin;
Solomonov, Inna;
Zajac, Ewa;
Saldova, Radka;
Senske, Michael;
Ugarte-Berzal, Estefanía;
Martens, Erik;
Van den Steen, Philippe E.;
Van Damme, Jo;
Garcia-Pardo, Angeles;
Froeyen, Matheus;
Deryugina, Elena I.;
Quigley, James P.;
Moestrup, Søren K.;
Rudd, Pauline M.;
Sagi, Irit;
Opdenakker, Ghislain

Publication type:

Article

Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans.

Published in:

Biochemical Journal, 2013, v. 453, n. 1, p. 83, doi. 10.1042/BJ20130166

By:

GISLER, Claudio;
LüSCHER, Daniel;
SCHÄTZLE, Philipp;
DÜRR, Stephanie;
BAICI, Antonio;
GALLICIOTTI, Giovanna;
REIF, Raymond;
BOLLIGER, Marc F.;
KUNZ, Beat;
SONDEREGGER, Peter

Publication type:

Article

Enhancement of Streptomyces transglutaminase activity and pro-peptide cleavage efficiency by introducing linker peptide in the C-terminus of the pro-peptide.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 3/4, p. 317, doi. 10.1007/s10295-012-1221-y

By:

Chen, Kangkang;
Liu, Song;
Wang, Guangsheng;
Zhang, Dongxu;
Du, Guocheng;
Chen, Jian;
Shi, Zhongping

Publication type:

Article

The Efficacy of IV Tissue Plasminogen Activator for Restoring Cerebral Blood Flow in the Hours Immediately after Administration in Patients with Acute Stroke.

Published in:

2019

By:

NIH Natural History of Stroke Investigators;
Simpkins, Alexis N.;
Leigh, Richard;
Majidi, Shahram

Publication type:

journal article

Characterization and molecular docking study of cathepsin L inhibitory peptides (SnuCalCpIs) from Calotropis procera R. Br.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09854-x

By:

Kwon, Chang Woo;
Yeo, Subin;
Chang, Pahn-Shick

Publication type:

Article

On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation.

Published in:

FEBS Open Bio, 2023, v. 13, n. 6, p. 1095, doi. 10.1002/2211-5463.13575

By:

Chua, Niying;
Wong, Yee Hwa;
El Sahili, Abbas;
Liu, Chuan Fa;
Lescar, Julien

Publication type:

Article

UTILIZAÇÃO DE PROBIÓTICOS SOBRE O GANHO DE PESO EM BOVINOS DA RAÇA NELORE.

Published in:

Colloquium Agrariae, 2013, v. 9, n. 1, p. 25, doi. 10.5747/ca.2013.v09.n1.a086

By:

Stevanato de Almeida, Luis Eduardo;
Cristina Genaro, Sandra;
de Souza Geroti, Thais Cristina;
Frazatti Galina, Neuza Maria;
Giuffrida, Rogerio;
Eduardo Pardo, Paulo;
Penha, Luciana;
Camacho, Reinaldo;
Oliveira Santos, Marcos

Publication type:

Article

Light and Electron Microscopic Studies on Prenatal Differentiation of Exocrine Pancreas in Buffalo.

Published in:

Veterinary Medicine International, 2016, p. 1, doi. 10.1155/2016/2414769

By:

Gupta, Divya;
Uppal, Varinder;
Bansal, Neelam;
Gupta, Anuradha

Publication type:

Article

Serological diagnosis and prognosis of severe acute pancreatitis by analysis of serum glycoprotein 2.

Published in:

Clinical Chemistry & Laboratory Medicine, 2017, v. 55, n. 6, p. 854, doi. 10.1515/cclm-2016-0797

By:

Roggenbuck, Dirk;
Goihl, Alexander;
Hanack, Katja;
Holzlöhner, Pamela;
Hentschel, Christian;
Veiczi, Miklos;
Schierack, Peter;
Reinhold, Dirk;
Schulz, Hans-Ulrich

Publication type:

Article