Works about YAP signaling proteins

Results: 870

Retracted: Gallic acid from Terminalia chebula inhibited the growth of esophageal carcinoma cells by suppressing the Hippo signal pathway.

Published in:

Iranian Journal of Basic Medical Sciences, 2025, v. 28, n. 8, p. 1401, doi. 10.22038/ijbms.2020.42283.9982

By:

Gui-Li Sun;
Dong Wang

Publication type:

Article

Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61057-w

By:

Shao, Jingchen;
Kwon, Jeonghyeon;
Wang, Tianpeng;
Günther, Stefan;
Tombor, Lukas S.;
Warwick, Timothy;
Shaheryar, Zaib;
Brandes, Ralf P.;
Dimmeler, Stefanie;
Wenzel, Jan;
Offermanns, Stefan;
Schwaninger, Markus;
Wettschureck, Nina

Publication type:

Article

PP1γ promotes esophageal squamous cell carcinoma progression through the PP1γ/YAP1/SOX2 axis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1586679

By:

Du, Juan;
Liu, Li;
Zheng, Shutao;
Dai, Chenglu;
Liu, Jingyu;
Zhang, Wei;
Pu, Hongwei;
Xue, Jing

Publication type:

Article

Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1545952

By:

Zhang, Lingqiu;
Zhang, Fan;
Liang, Haimei;
Qin, Xiangling;
Mo, Yuemi;
Chen, Shiyi;
Xie, Jinling;
Hou, Xiaotao;
Deng, Jiagang;
Hao, Erwei;
Du, Zhengcai

Publication type:

Article

STK3 is a transcriptional target of YAP1 and a hub component in the crosstalk between Hippo and Wnt signaling pathways during gastric carcinogenesis.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02391-x

By:

Xie, Fuda;
Lyu, Yang;
Chen, Bonan;
Leung, Hoi Wing;
Yu, Peiyao;
Feng, Tiejun;
Fang, Canbin;
Cheung, Alvin H.K.;
Zhou, Bin;
Jiang, Jianhui;
Zhang, Ge;
Xu, Dazhi;
Li, Liang;
Jiang, Chen;
Chen, Jianwu;
Zhou, Zhaocai;
An, Liwei;
Huang, Bing;
Zhuang, Kangmin;
Luo, Xiaobei

Publication type:

Article

Dual functions of the ΔNp63-miR-141-3p-YAP1 regulatory axis in cervical cancer progression are dependent on histological subtype.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07237-6

By:

Panahi-Moghadam, Somayeh;
Sadeghizadeh, Majid;
Farivar, Shirin;
Vakhshiteh, Faezeh

Publication type:

Article

Targeting the disrupted Hippo signaling to prevent neoplastic renal epithelial cell immune evasion.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57697-7

By:

Lv, Xiangmin;
Liu, Jiyuan;
Ruan, Jinpeng;
Chen, Peichao;
He, Chunbo;
Zhao, Xingeng;
Huang, Cong;
Chen, Li;
Wang, Hongbo;
Hua, Guohua;
Shi, Davie;
Yang, Siyi;
Moness, Madelyn L.;
Montoute, Isabelle;
Dhar, Anjali;
Chen, Xingcheng;
Kumar, Raj;
Hu, Lu;
Sadreyev, Ruslan;
Yeku, Oladapo

Publication type:

Article

Honokiol regulates ovarian cancer cell malignant behavior through YAP/TAZ pathway modulation.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 6, p. 1010, doi. 10.1111/jog.15940

By:

Liu, Fang;
Zhang, Yufang;
Xia, Xinyi;
Han, Jing;
Cao, Linyan

Publication type:

Article

Honokiol induces ferroptosis in ovarian cancer cells through the regulation of YAP by OTUB2.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 5, p. 864, doi. 10.1111/jog.15922

By:

Liu, Fang;
Zhang, Yufang;
Xia, Xinyi;
Han, Jing;
Cao, Linyan

Publication type:

Article

Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00649-y

By:

Li, Yunchao;
Wang, Xiaoxiao;
Pan, Changyu;
Yuan, Hui;
Li, Xinyi;
Chen, Zejun;
He, Haoyu

Publication type:

Article

Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00613-w

By:

Ko, Hung-Shuo;
Laiman, Vincent;
Tsao, Po-Nien;
Chen, Chung-Ming;
Chuang, Hsiao-Chi

Publication type:

Article

Natural compound library screening to identify berberine as a treatment for rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 3, p. 959, doi. 10.1007/s10067-024-06871-1

By:

Zhang, Li;
Tan, Min;
Mao, Jing;
Zhang, Juan;
Wang, Xiao-Yuan;
Zhang, Yan;
Duo, Rui-Xue;
Hao, Jia-Yao;
Shen, Hai-Li

Publication type:

Article

Yes-associated protein is dysregulated during nitrofen-induced hypoplastic lung development due to congenital diaphragmatic hernia.

Published in:

Pediatric Surgery International, 2022, v. 38, n. 5, p. 713, doi. 10.1007/s00383-022-05099-x

By:

Kahnamoui, Shana;
Khoshgoo, Naghmeh;
Patel, Daywin;
Wagner, Richard;
Keijzer, Richard

Publication type:

Article

Loss of Mst1/2 activity promotes non-mitotic hair cell generation in the neonatal organ of Corti.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00261-4

By:

Lu, Xiaoling;
Yu, Huiqian;
Ma, Jiaoyao;
Wang, Kunkun;
Guo, Luo;
Zhang, Yanping;
Li, Boan;
Zhao, Zehang;
Li, Huawei;
Sun, Shan

Publication type:

Article

ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00251-6

By:

Xu, Jianliang;
Kausalya, P. Jaya;
Ong, Alicia Ghia Min;
Goh, Christine Meng Fan;
Mohamed Ali, Safiah;
Hunziker, Walter

Publication type:

Article

Regulation of ER stress-induced apoptotic and inflammatory responses via YAP/TAZ-mediated control of the TRAIL-R2/DR5 signaling pathway.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02335-w

By:

El Yousfi, Y.;
Fernández-Farrán, F. J.;
Oliver, F. J.;
López-Rivas, A.;
Yerbes, R.

Publication type:

Article

ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-024-02249-z

By:

Sun, Liang;
Lu, Ting;
Jiang, Linhua;
Yao, Huihui;
Xu, Qixuan;
Sun, Jie;
Yang, Xiaoqin;
He, Songbing;
Zhu, Xinguo

Publication type:

Article

The long noncoding RNA ELFN1-AS1 promotes gastric cancer growth and metastasis by interacting with TAOK1 to inhibit the Hippo signaling pathway.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02235-5

By:

Wang, Yuanhang;
Shen, Kuan;
Cheng, Quan;
Zhou, Xinyi;
Liu, Kanghui;
Xiao, Jian;
Hu, Li

Publication type:

Article

Regulation of Hippo/YAP axis in colon cancer progression by the deubiquitinase JOSD1.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02136-7

By:

Sun, Yanan;
Liu, Dongyi;
Zhang, Xiaobo;
Su, Peng;
Li, Xin;
Li, Zhongbo;
Gai, Yingwen;
Li, Jingying;
Yang, Zhiyong;
Ding, Yinlu;
Zhu, Jian;
Tan, Xiaodong

Publication type:

Article

The roles of Hippo/YAP signaling pathway in physical therapy.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01972-x

By:

Pan, Chunran;
Hao, Xiaoxia;
Deng, Xiaofeng;
Lu, Fan;
Liu, Jiawei;
Hou, Wenjie;
Xu, Tao

Publication type:

Article

Uveitic glaucoma-like features in Yap conditional knockout mice.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-023-01791-6

By:

Bitard, Juliette;
Grellier, Elodie-Kim;
Lourdel, Sophie;
Filipe, Helena Prior;
Hamon, Annaïg;
Fenaille, François;
Castelli, Florence Anne;
Chu-Van, Emeline;
Roger, Jérôme E.;
Locker, Morgane;
Perron, Muriel

Publication type:

Article

Fibroblast Yap/Taz Signaling in Extracellular Matrix Homeostasis and Tissue Fibrosis.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 12, p. 3358, doi. 10.3390/jcm13123358

By:

Chu, Cong-Qiu;
Quan, Taihao

Publication type:

Article

Molecular Mechanism of Curcumin Derivative on YAP Pathway against Ovarian Cancer.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 23, p. 7220, doi. 10.3390/jcm11237220

By:

Zheng, Nan;
Liu, Shan;
Zeng, Huiting;
Zhao, Huajun;
Jin, Lixu

Publication type:

Article

SU4312 Represses Glioma Progression by Inhibiting YAP and Inducing Sensitization to the Effect of Temozolomide.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 16, p. 4765, doi. 10.3390/jcm11164765

By:

Wang, Xu;
Zhou, Yi;
Wang, Yan;
Wang, Xiang;
Zhang, Yu;
Mao, Yufei;
Zhang, Long;
Qi, Ji;
Zhang, Yining;
Lyu, Feng;
Gu, Linbo;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

Analysis of Yes-Associated Protein-1 (YAP1) Target Gene Signature to Predict Progressive Breast Cancer.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 7, p. 1947, doi. 10.3390/jcm11071947

By:

Venkatasubramanian, Gomathi;
Kelkar, Devaki A.;
Mandal, Susmita;
Jolly, Mohit Kumar;
Kulkarni, Madhura

Publication type:

Article

虎杖苷通过Hippo/YAP通路影响甲状腺癌8505C细胞的恶性生物学行为和顺铂敏感性.

Published in:

Chinese Journal of Cancer Biotherapy, 2024, v. 31, n. 3, p. 224, doi. 10.3872/j.issn.1007-385x.2024.03.003

By:

曹建中;
黄金石;
丁亚亭

Publication type:

Article

YAP/TAZ在肾细胞癌发生发展中作用及其机制的研究进展.

Published in:

Chinese Journal of Cancer Biotherapy, 2023, v. 30, n. 12, p. 1105, doi. 10.3872/j.issn.1007-385x.2023.12.010

By:

杨懿人;
王林辉;
甘欣欣

Publication type:

Article

Hippo-YAP/TAZ信号通路调控铁死亡对肿瘤影响的研究进展.

Published in:

Chinese Journal of Cancer Biotherapy, 2023, v. 30, n. 10, p. 919, doi. 10.3872/j.issn.1007-385x.2023.10.011

By:

刘靖芳

Publication type:

Article

Mechanical Properties of Glioblastoma: Perspectives for YAP/TAZ Signaling Pathway and Beyond.

Published in:

Diseases, 2023, v. 11, n. 2, p. 86, doi. 10.3390/diseases11020086

By:

Pontes, Bruno;
Mendes, Fabio A.

Publication type:

Article

Novel Roles of the Greatwall Kinase Rim15 in Yeast Oxidative Stress Tolerance through Mediating Antioxidant Systems and Transcriptional Regulation.

Published in:

Antioxidants, 2024, v. 13, n. 3, p. 260, doi. 10.3390/antiox13030260

By:

Wang, Xue-Qing;
Yuan, Bing;
Zhang, Feng-Li;
Liu, Chen-Guang;
Auesukaree, Choowong;
Zhao, Xin-Qing

Publication type:

Article

AMPK-Dependent YAP Inhibition Mediates the Protective Effect of Metformin against Obesity-Associated Endothelial Dysfunction and Inflammation.

Published in:

Antioxidants, 2023, v. 12, n. 9, p. 1681, doi. 10.3390/antiox12091681

By:

Kang, Lijing;
Yi, Juanjuan;
Lau, Chi-Wai;
He, Lei;
Chen, Qinghua;
Xu, Suowen;
Li, Jun;
Xia, Yin;
Zhang, Yuanting;
Huang, Yu;
Wang, Li

Publication type:

Article

YAP Inhibition Alleviates Simulated Microgravity-Induced Mesenchymal Stem Cell Senescence via Targeting Mitochondrial Dysfunction.

Published in:

Antioxidants, 2023, v. 12, n. 5, p. 990, doi. 10.3390/antiox12050990

By:

Lv, Wenjun;
Peng, Xiufen;
Tu, Yun;
Shi, Yisong;
Song, Guanbin;
Luo, Qing

Publication type:

Article

Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair.

Published in:

Antioxidants, 2023, v. 12, n. 4, p. 850, doi. 10.3390/antiox12040850

By:

Nettleford, Shaneice K.;
Liao, Chang;
Short, Sarah P.;
Rossi, Randall M.;
Singh, Vishal;
Prabhu, K. Sandeep

Publication type:

Article

Hippo pathway-mediated YAP1/ TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.84532

By:

Yifan Wu;
Kunhua Qin;
Yi Xu;
Rajhans, Shreya;
Vo, Truong;
Lopez, Kevin M;
Jun Liu;
Nipper, Michael H;
Deng, Janice;
Xue Yin;
Ramjit, Logan R;
Zhenqing Ye;
Yu Luan;
Arda, H. Efsun;
Pei Wang

Publication type:

Article

YAP/TAZ enhances P-body formation to promote tumorigenesis.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.88573

By:

Xia Shen;
Xiang Peng;
YueGui Guo;
Zhujiang Dai;
Long Cui;
Wei Yu;
Yun Liu;
Chen-Ying Liu

Publication type:

Article

Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.95640

By:

Wei Chen;
Yun Lu;
Yan Zhang;
Jinjin Wu;
McVicar, Abigail;
Yilin Chen;
Siyu Zhu;
Guochun Zhu;
You Lu;
Jiayang Zhang;
McConnell, Matthew;
Yi-Ping Li

Publication type:

Article

The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.90818

By:

Phillips, Jonathan E.;
Duojia Pan

Publication type:

Article

TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87394

By:

Grove, Matthew;
Hyukmin Kim;
Shuhuan Pang;
Amaya, Jose Paz;
Guoqing Hu;
Jiliang Zhou;
Lemay, Michel;
Young-Jin Son

Publication type:

Article

Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.88508

By:

Bulos, Maya L.;
Grzelak, Edyta M.;
Li-Ma, Chloris;
Chen, Emily;
Hull, Mitchell;
Johnson, Kristen A.;
Bollong, Michael J.

Publication type:

Article

Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85092

By:

Warren, Rachel;
Handeng Lyu;
Klinkhammer, Kylie;
De Langhe, Stijn P.

Publication type:

Article

Shear and hydrostatic stress regulate fetal heart valve remodeling through YAP-mediated mechanotransduction.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83209

By:

Mingkun Wang;
Belle Yanyu Lin;
Shuofei Sun;
Charles Dai;
Feifei Long;
Butcher, Jonathan T.

Publication type:

Article

MitoQ alleviates carbon tetrachloride-induced liver fibrosis in mice through regulating JNK/YAP pathway.

Published in:

Toxicology Research, 2022, v. 11, n. 5, p. 852, doi. 10.1093/toxres/tfac062

By:

Shan, Shulin;
Liu, Zhaoxiong;
Liu, Zhidan;
Zhang, Cuiqin;
Song, Fuyong

Publication type:

Article

Down-regulation of YAP prevents smoking- and alcohol-induced carcinogenesis of esophageal paracancerous tissue by promoting cellular pyroptosis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98952-7

By:

Ding, Xinyu;
Li, Ying;
Wang, Xuning;
Li, Fan;
Xu, Zhifei;
Zhu, Yongfei;
Chen, Zihao

Publication type:

Article

Celastrol loaded nanocomplex for painless tumor therapy via YAP inhibition.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-97055-7

By:

Hao, Zhaokun;
Zhou, Yuming;
Zhang, Yuqiang;
Wang, Danyang;
Wei, Yiying;
Ji, Xiaopu;
Sun, Wan Ru;
Wang, Pingyu;
Li, YouJie;
Lopez, Irene Bautista;
Pedraz, José Luis;
Ramalingam, Murugan;
Xie, Shuyang;
Wang, Ranran

Publication type:

Article

The YAP/TEAD4 transcriptional complex in intestinal macrophages promotes M2 polarization and alleviates DSS-induced colitis via the regulation of C/EBPβ.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-95933-8

By:

Wang, Su;
Zou, Fei;
Xu, Mengmeng;
Wu, Zengrong;
Xia, Pianpian;
Deng, Feihong

Publication type:

Article

Matrix stiffness changes affect astrocyte phenotype in an in vitro injury model.

Published in:

NPG Asia Materials, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41427-021-00304-0

By:

Hu, Yan;
Huang, Guoyou;
Tian, Jin;
Qiu, Jinbin;
Jia, Yuanbo;
Feng, Dayun;
Wei, Zhao;
Li, Sidi;
Xu, Feng

Publication type:

Article

Anti-TNBC effects of Lappaol F by targeting epithelial-mesenchymal transition via regulation of GSK-3β/YAP/β-catenin and PI3K/AKT pathways.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1496511

By:

Meng, Qiqi;
Li, Zhiping;
He, Xiaofeng;
Hu, Yuanhao;
Wu, Guiyun;
Huang, Jiawen;
Luo, Zhuohui;
Hu, Yingjie;
Shen, Xiaoling

Publication type:

Article

Icariin modulates osteogenic and adipogenic differentiation in ADSCs via the Hippo-YAP/TAZ pathway: a novel therapeutic strategy for osteoporosis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1510561

By:

Lin, Shaozi;
Meng, Zuyu;
Wang, Mei;
Ye, Zixuan;
Long, Mengsha;
Zhang, Yiyao;
Liu, Fang;
Chen, Hongling;
Li, Menghan;
Qin, Jiajia;
Liu, Haiquan

Publication type:

Article

Icariin promotes functional recovery in rats after spinal cord injury by inhibiting YAP and regulating PPM1B ubiquitination to inhibiting the activation of reactive astrocytes.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1434652

By:

Feng, Sa;
Liu, Linyan;
Cheng, Yuelin;
Zhou, Mengmeng;
Zhu, Haoqiang;
Zhao, Xinyan;
Chen, Ziyu;
Kan, Shunli;
Fu, Xuanhao;
Hu, Wei;
Zhu, Rusen

Publication type:

Article

ER stress-induced YAP upregulation leads to chondrocyte phenotype loss in age-related osteoarthritis.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1476255

By:

Gao, Yanchun;
Wei, Haifeng;
Peng, Xiaoyuan;
Wang, Chenchen;
Zhu, Hongyi;
Yin, Junhui

Publication type:

Article