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YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis.
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- Gastric Cancer, 2024, v. 27, n. 4, p. 785, doi. 10.1007/s10120-024-01508-3
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- Article
Pitavastatin sensitizes the EGFR-TKI associated resistance in lung cancer by inhibiting YAP/AKT/BAD-BCL-2 pathway.
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- Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03416-z
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- Article
Tudor-SN promotes cardiomyocyte proliferation and neonatal heart regeneration through regulating the phosphorylation of YAP.
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- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01715-6
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- Article
Effect of miR-15a-5p on autophagy of placental trophoblasts in preeclampsia.
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- Journal of Practical Medicine / Shiyong Yixue Zazhi, 2024, v. 40, n. 12, p. 1631, doi. 10.3969/j.issn.1006-5725.2024.12.004
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- Article
NF2-Related Schwannomatosis (NF2): Molecular Insights and Therapeutic Avenues.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6558, doi. 10.3390/ijms25126558
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- Article
G6PD and ACSL3 are synthetic lethal partners of NF2 in Schwann cells.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49298-7
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- Article
The RNF214-TEAD-YAP signaling axis promotes hepatocellular carcinoma progression via TEAD ubiquitylation.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49045-y
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- Article
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49230-z
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- Article
A Novel Mechanism of MSCs Responding to Occlusal Force for Bone Homeostasis.
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- Journal of Dental Research, 2024, v. 103, n. 6, p. 642, doi. 10.1177/00220345241236120
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- Article
Honokiol regulates ovarian cancer cell malignant behavior through YAP/TAZ pathway modulation.
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- Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 6, p. 1010, doi. 10.1111/jog.15940
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- Article
Low concentrations of saracatinib promote definitive endoderm differentiation through inhibition of FAK-YAP signaling axis.
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- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01679-7
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- Article
Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00484-z
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- Article
Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.95640
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- Article
A connection between phosphatidylinositol 5-phosphate and the Hippo pathway to prevent epithelial-mesenchymal transition in cancer.
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- Science Signaling, 2024, v. 17, n. 838, p. 1, doi. 10.1126/scisignal.adp3504
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- Article
Hippo and PI5P4K signaling intersect to control the transcriptional activation of YAP.
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- Science Signaling, 2024, v. 17, n. 838, p. 1, doi. 10.1126/scisignal.ado6266
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- Article
Regulation of YAP and Wnt signaling by the endosomal protein MAMDC4.
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- PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0296003
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- Article
Editorial: Targeting ion homeostasis for cancer therapy: mechanisms and immunomodulatory effects.
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- Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1418700
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- Article
TSG-6-Mediated Extracellular Matrix Modifications Regulate Hypoxic-Ischemic Brain Injury.
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- Journal of Neuroscience, 2024, v. 44, n. 21, p. 1, doi. 10.1523/JNEUROSCI.2215-23.2024
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- Article
YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells.
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- Respiratory Research, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12931-024-02832-z
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- Article
Leveraging the Fragment Molecular Orbital and MM-GBSA Methods in Virtual Screening for the Discovery of Novel Non-Covalent Inhibitors Targeting the TEAD Lipid Binding Pocket.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5358, doi. 10.3390/ijms25105358
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- Article
Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48179-3
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- Article
Generation of Anterior Segment of the Eye Cells from hiPSCs in Microfluidic Platforms.
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- Advanced Biology, 2024, v. 8, n. 5, p. 1, doi. 10.1002/adbi.202400018
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- Article
Farnesoid X Receptor Protects Murine Lung against IL-6–promoted Ferroptosis Induced by Polyriboinosinic-Polyribocytidylic Acid.
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- American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 5, p. 364, doi. 10.1165/rcmb.2023-0172OC
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- Article
Dynamic relationship among extracellular matrix and body wall cells in Hirudo verbana morphogenesis.
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- Cell & Tissue Research, 2024, v. 396, n. 2, p. 213, doi. 10.1007/s00441-024-03874-x
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- Article
YAP prevents senescence of dermal fibroblast and inhibits melanogenesis via paracrine effect of DKK1.
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- Experimental Dermatology, 2024, v. 33, n. 5, p. 1, doi. 10.1111/exd.15093
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- Article
Honokiol induces ferroptosis in ovarian cancer cells through the regulation of YAP by OTUB2.
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- Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 5, p. 864, doi. 10.1111/jog.15922
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- Publication type:
- Article
Inhibition of Connective Tissue Growth Factor Expression in Adult Retinal Pigment Epithelial-19 Cells by Blocking Yes-Associated Protein/Transcriptional Coactivator with PDZ-Binding Motif Activity.
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- Journal of Ocular Pharmacology & Therapeutics, 2024, v. 40, n. 4, p. 246, doi. 10.1089/jop.2023.0141
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- Article
The roles of Hippo/YAP signaling pathway in physical therapy.
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- Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01972-x
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- Article
Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma.
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- Cancers, 2024, v. 16, n. 8, p. 1593, doi. 10.3390/cancers16081593
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- Article
Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.
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- Molecules, 2024, v. 29, n. 8, p. 1729, doi. 10.3390/molecules29081729
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- Article
Enhancing the productivity and proliferation of CHO-K1 cells by oncoprotein YAP (Yes-associated protein).
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- Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-024-13122-5
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- Article
CCDC25 suppresses clear cell renal cell carcinoma progression by LATS1/YAP-mediated regulation of the hippo pathway.
- Published in:
- Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03318-0
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- Article
Hippo Signaling at the Hallmarks of Cancer and Drug Resistance.
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- Cells (2073-4409), 2024, v. 13, n. 7, p. 564, doi. 10.3390/cells13070564
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- Article
ZO-1 Regulates Hippo-Independent YAP Activity and Cell Proliferation via a GEF-H1- and TBK1-Regulated Signalling Network.
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- Cells (2073-4409), 2024, v. 13, n. 7, p. 640, doi. 10.3390/cells13070640
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- Article
Identification of PTPN12 Phosphatase as a Novel Negative Regulator of Hippo Pathway Effectors YAP/TAZ in Breast Cancer.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 4064, doi. 10.3390/ijms25074064
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- Article
Reversible and monitorable nephrotoxicity in rats by the novel potent transcriptional enhanced associate domain (TEAD) inhibitor, K-975.
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- Journal of Toxicological Sciences, 2024, v. 49, n. 4, p. 175, doi. 10.2131/jts.49.175
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- Article
Mechanisms of mechanical force aggravating periodontitis: A review.
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- Oral Diseases, 2024, v. 30, n. 3, p. 895, doi. 10.1111/odi.14566
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- Article
17β-Estradiol promotes metastasis in triple-negative breast cancer through the Calpain/YAP/β-catenin signaling axis.
- Published in:
- PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0298184
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- Article
Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46531-1
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- Article
TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.87394
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- Article
The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.90818
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- Article
Role of hippo pathway and cuproptosis-related genes in immune infiltration and prognosis of skin cutaneous melanoma.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1344755
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- Publication type:
- Article
Hypoxia-inducible factor-2α promotes fibrosis in nonalcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells.
- Published in:
- Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1344971
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- Article
Low-intensity pulsed ultrasound delays the progression of osteoarthritis by regulating the YAP–RIPK1–NF-κB axis and influencing autophagy.
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- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05086-x
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- Article
YAP1/TAZ Mediates Rumen Epithelial Cell Proliferation but Not Short-Chain Fatty Acid Metabolism In Vitro.
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- Animals (2076-2615), 2024, v. 14, n. 6, p. 922, doi. 10.3390/ani14060922
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- Article
STAT3–mediated up-regulation of DAB2 via SRC-YAP1 signaling axis promotes Helicobacter pylori-driven gastric tumorigenesis.
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- Biomarker Research, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40364-024-00577-x
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- Article
GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation.
- Published in:
- Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-00930-4
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- Article
Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46193-z
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- Article
AMPK stimulation inhibits YAP/TAZ signaling to ameliorate hepatic fibrosis.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55764-5
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- Article
RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway.
- Published in:
- Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03282-9
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- Article