Works matching DE "WORTMANNIN"

Results: 64

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling.

Published in:

BioMetals, 2014, v. 27, n. 2, p. 317, doi. 10.1007/s10534-014-9714-y

By:

Hamann, Ingrit;
Petroll, Kerstin;
Hou, Xiaoqing;
Anwar-Mohamed, Anwar;
El-Kadi, Ayman;
Klotz, Lars-Oliver

Publication type:

Article

Wortmannin-induced vacuole fusion enhances amyloplast dynamics in Arabidopsis zigzag1 hypocotyls.

Published in:

Journal of Experimental Botany, 2016, v. 67, n. 22, p. 6459, doi. 10.1093/jxb/erw418

By:

Alvarez, Ashley Ann;
Sang Won Han;
Masatsugu Toyota;
Brillada, Carla;
Jiameng Zheng;
Gilroy, Simon;
Rojas-Pierce, Marcela

Publication type:

Article

Роль і регуляція фосфоліпази Д у сигнальному каскаді інсуліну в мозку.

Published in:

Physiological Journal / Fiziologichnyi Zhurnal, 2018, v. 64, n. 2, p. 40

By:

Бабенко, Н. О.;
Харченко, В. С.

Publication type:

Article

Autophagy enhances the replication of Peste des petits ruminants virus and inhibits caspase-dependent apoptosis in vitro.

Published in:

Virulence, 2018, v. 9, n. 1, p. 1176, doi. 10.1080/21505594.2018.1496776

By:

Yang, Bo;
Xue, Qinghong;
Qi, Xuefeng;
Wang, Xueping;
Jia, Peilong;
Chen, Shuying;
Wang, Ting;
Xue, Tianxia;
Wang, Jingyu

Publication type:

Article

PI3K/Akt Pathway is Required for Spinal Central Sensitization in Neuropathic Pain.

Published in:

Cellular & Molecular Neurobiology, 2018, v. 38, n. 3, p. 747, doi. 10.1007/s10571-017-0541-x

By:

Liu, Wei;
Lv, Yanling;
Ren, Facheng

Publication type:

Article

CL316243 Induces Phosphatidylinositol 3,4,5-triphosphate Production in Rat Adipocytes in an Adenosine Deaminase-, Pertussis Toxin-, or Wortmannin-Sensitive Manner.

Published in:

Physiological Research, 2016, v. 65, n. 3, p. 543, doi. 10.33549/physiolres.933162

By:

OHSAKA, Y.;
NOMURA, Y.

Publication type:

Article

Activation of EGFR-PI3K-AKT signaling is required for Mycoplasma hyorhinis-promoted gastric cancer cell migration.

Published in:

Cancer Cell International, 2014, v. 14, n. 1, p. 97, doi. 10.1186/s12935-014-0135-3

By:

Hongying Duan;
Like Qu;
Chengchao Shou

Publication type:

Article

Evolving possible link between PI3K and NO pathways in neuroprotective mechanism of ischemic postconditioning in mice.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 397, n. 1/2, p. 255, doi. 10.1007/s11010-014-2193-1

By:

Gulati, Puja;
Singh, Nirmal

Publication type:

Article

Inhibition of TREK-2 K channels by PI(4,5)P: an intrinsic mode of regulation by intracellular ATP via phosphatidylinositol kinase.

Published in:

Pflügers Archiv: European Journal of Physiology, 2016, v. 468, n. 8, p. 1389, doi. 10.1007/s00424-016-1847-0

By:

Woo, Joohan;
Shin, Dong;
Kim, Hyun;
Yoo, Hae;
Zhang, Yin-Hua;
Nam, Joo;
Kim, Woo;
Kim, Sung

Publication type:

Article

A role of autophagy in Trypanosoma brucei cell death.

Published in:

Cellular Microbiology, 2012, v. 14, n. 8, p. 1242, doi. 10.1111/j.1462-5822.2012.01795.x

By:

Li, Feng-Jun;
Shen, Qian;
Wang, Chao;
Sun, Ying;
Yuan, Adam Y.;
He, Cynthia Y.

Publication type:

Article

TNF-α Mediated Secretory Component is Positively Regulated by PI3K/AKT/MTOR in CACO-2 Cells.

Published in:

Journal of Medical Biochemistry, 2013, v. 32, n. 2, p. 116, doi. 10.2478/jomb-2013-0008

By:

Liu, Dongyan;
Wang, Si;
Jiang, Teng;
Ding, Peng

Publication type:

Article

Regulatory Roles of the PI3K/Akt Signaling Pathway in Rats with Severe Acute Pancreatitis.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081767

By:

Xu, Ping;
Wang, Jing;
Yang, Zhi-wen;
Lou, Xiao-li;
Chen, Cheng

Publication type:

Article

Cardioprotective Effect of Ghrelin in Cardiopulmonary Bypass Involves a Reduction in Inflammatory Response.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055021

By:

Yukun Cao;
Jun Tang;
Ting Yang;
Heng Ma;
Dinghua Yi;
Chunhu Gu;
Shiqiang Yu

Publication type:

Article

Repair of DNA Strand Breaks in a Minichromosome In Vivo: Kinetics, Modeling, and Effects of Inhibitors.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0052966

By:

Kumala, Slawomir;
Fujarewicz, Krzysztof;
Jayaraju, Dheekollu;
Rzeszowska-Wolny, Joanna;
Hancock, Ronald

Publication type:

Article

Integrin αIIb-Mediated PI3K/Akt Activation in Platelets.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047356

By:

Haixia Niu;
Xue Chen;
Ralph A. Gruppo;
Ding Li;
Yanhua Wang;
Lin Zhang;
Kemin Wang;
Weiran Chai;
Yueping Sun;
Zhongren Ding;
T. Kent Gartner;
Junling Liu

Publication type:

Article

Wortmannin Reduces Insulin Signaling and Death in Seizure-Prone Pcmt1<sup>-/-</sup> Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046719

By:

MacKay, Kennen B.;
Lowenson, Jonathan D.;
Clarke, Steven G.

Publication type:

Article

Regulation of NF-κB Activation through a Novel PI-3K-Independent and PKA/Akt-Dependent Pathway in Human Umbilical Vein Endothelial Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046528

By:

Balwani, Sakshi;
Chaudhuri, Rituparna;
Nandi, Debkumar;
Jaisankar, Parasuraman;
Agrawal, Anurag;
Ghosh, Balaram

Publication type:

Article

NFAT5 Is Activated by Hypoxia: Role in Ischemia and Reperfusion in the Rat Kidney.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0039665

By:

Villanueva, Sandra;
Suazo, Cristian;
Santapau, Daniela;
Pérez, Francisco;
Quiroz, Mariana;
Carreño, Juan E.;
Illanes, Sebastián;
Lavandero, Sergio;
Michea, Luis;
Irarrazabal, Carlos E.

Publication type:

Article

Luteolin Limits Infarct Size and Improves Cardiac Function after Myocardium Ischemia/Reperfusion Injury in Diabetic Rats.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033491

By:

Dongdong Sun;
Jie Huang.;
Zheng Zhang;
Haokao Gao;
Jiayi Li;
Min Shen;
Feng Cao;
Haichang Wang

Publication type:

Article

Activation of Akt by the Bacterial Inositol Phosphatase, SopB, is Wortmannin Insensitive.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022260

By:

Cooper, Kendal G.;
Winfree, Seth;
Malik-Kale, Preeti;
Jolly, Carrie;
Ireland, Robin;
Knodler, Leigh A.;
Steele-Mortimer, Olivia

Publication type:

Article

P154 Wortmannin abolishes the protective effect of simvastatin against the ischaemia and reperfusion-induced ventricular arrhythmias in the anaesthetized canine.

Published in:

Cardiovascular Research, 2014, v. 103, n. suppl_1, p. S27, doi. 10.1093/cvr/cvu082.92

By:

Kisvari, G;
Seprenyi, GY;
Vegh, A

Publication type:

Article

Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, induces accumulation of DNA double-strand breaks.

Published in:

Journal of Radiation Research, 2020, v. 61, n. 2, p. 171, doi. 10.1093/jrr/rrz102

By:

Ihara, Makoto;
Shichijo, Kazuko;
Takeshita, Satoshi;
Kudo, Takashi

Publication type:

Article

Autophagy-related (ATG) 11, ATG9 and the phosphatidylinositol 3-kinase control ATG2-mediated formation of autophagosomes in Arabidopsis.

Published in:

Plant Cell Reports, 2018, v. 37, n. 4, p. 653, doi. 10.1007/s00299-018-2258-9

By:

Kang, Sangwoo;
Shin, Kwang Deok;
Kim, Jeong Hun;
Chung, Taijoon

Publication type:

Article

Extracellular signal-regulated kinases 1/2 and Akt contribute to triclosan-stimulated proliferation of JB6 Cl 41-5a cells.

Published in:

Archives of Toxicology, 2015, v. 89, n. 8, p. 1297, doi. 10.1007/s00204-014-1308-5

By:

Wu, Yuanfeng;
Beland, Frederick;
Chen, Si;
Fang, Jia-Long

Publication type:

Article

The N-Terminal Propeptide and the C Terminus of the Precursor to 20-kilo-dalton Potato Tuber Protein Can Function as Different Types of Vacuolar Sorting Signals.

Published in:

Plant & Cell Physiology, 1999, v. 40, n. 11, p. 1152, doi. 10.1093/oxfordjournals.pcp.a029500

By:

Koide, Yasuhiro;
Matsuoka, Ken;
Ohto, Masa-aki;
Nakamura, Kenzo

Publication type:

Article

Wortmannin induces MCF-7 breast cancer cell death via the apoptotic pathway, involving chromatin condensation, generation of reactive oxygen species, and membrane blebbing.

Published in:

Breast Cancer: Targets & Therapy, 2012, v. 4, p. 103, doi. 10.2147/BCTT.S31712

By:

Akter, Rozina;
Hossain, Md. Zakir;
Kleve, Maurice G.;
Gealt, Michael A.

Publication type:

Article

ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling.

Published in:

Autophagy, 2021, v. 17, n. 5, p. 1131, doi. 10.1080/15548627.2020.1749401

By:

Dalle Pezze, Piero;
Karanasios, Eleftherios;
Kandia, Varvara;
Manifava, Maria;
Walker, Simon A.;
Gambardella Le Novère, Nicolas;
Ktistakis, Nicholas T.

Publication type:

Article

Wortmannin and Li+ Specifically Inhibit Clathrin-Independent Endocytic Internalization of Bulk Fluid.

Published in:

Journal of Biochemistry, 1996, v. 119, n. 5, p. 887, doi. 10.1093/oxfordjournals.jbchem.a021326

By:

Sato, Satoshi B.;
Taguchi, Takahisa;
Yamashina, Shohei;
Toyama, Sakuji

Publication type:

Article

Prolactin Regulates Tuberoinfundibular Dopamine Neuron Discharge Pattern: Novel Feedback Control Mechanisms in the Lactotrophic Axis.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 23, p. 8074, doi. 10.1523/JNEUROSCI.0129-12.2012

By:

Lyons, David J.;
Hellysaz, Arash;
Broberger, Christian

Publication type:

Article

Isolation, characterization and antifungal docking studies of wortmannin isolated from Penicillium radicum.

Published in:

Scientific Reports, 2015, p. 11948, doi. 10.1038/srep11948

By:

Singh, Vineeta;
Praveen, Vandana;
Tripathi, C. K. M.;
Tripathi, Divya;
Haque, Shafiul;
Somvanshi, Pallavi;
Katti, S. B.

Publication type:

Article

The PI3K/Akt pathway mediates the expression of type I collagen induced by TGF-β2 in human retinal pigment epithelial cells.

Published in:

Graefe's Archive of Clinical & Experimental Ophthalmology, 2012, v. 250, n. 1, p. 15, doi. 10.1007/s00417-011-1766-x

By:

Yokoyama, Katsuhiko;
Kimoto, Kenichi;
Itoh, Yuji;
Nakatsuka, Kazuo;
Matsuo, Noritaka;
Yoshioka, Hidekatsu;
Kubota, Toshiaki

Publication type:

Article

Camel Whey Protein Disrupts the Cross-Talk Between PI3K and BCL-2 Signals and Mediates Apoptosis in Primary Acute Myeloid Leukemia Cells.

Published in:

Nutrition & Cancer, 2019, v. 71, n. 6, p. 1040, doi. 10.1080/01635581.2019.1595054

By:

Badr, Gamal;
Zahran, Asmaa M.;
Omar, Hossam M.;
Barsoum, Martina A.;
Mahmoud, Mohamed H.

Publication type:

Article

Meme Kanseri Hücre Dizilerinde HIF-1 alfa Ekspresyonunun PI3K/Akt Yolağı İnhibitörleri ile Kontrolü.

Published in:

Turkish Journal of Biochemistry / Turk Biyokimya Dergisi, 2012, v. 37, n. 3, p. 264, doi. 10.5505/tjb.2012.54254

By:

Dogan, A. Lale;
Çimen, Eren;
Oskay, Sevil;
Oksuz, Samet;
Guc, Dicle

Publication type:

Article

Inhibitory Effects of ML-9, Wortmannin, and Y-27632 on the Chemotaxis of Vascular Smooth Muscle Cells in Response to Platelet-Derived Growth Factor-BB1.

Published in:

Journal of Biochemistry, 2000, v. 128, n. 5, p. 719, doi. 10.1093/oxfordjournals.jbchem.a022806

By:

Kishi, Hiroko;
Bao, Jianjun;
Kohama, Kazuhiro

Publication type:

Article

Protective Effects of Pretreatment with Oleanolic Acid in Rats in the Acute Phase of Hepatic Ischemia-Reperfusion Injury: Role of the PI3K/Akt Pathway.

Published in:

Mediators of Inflammation, 2014, v. 2014, p. 1, doi. 10.1155/2014/451826

By:

Bo Gui;
Fuzhou Hua;
Jie Chen;
Zeping Xu;
Hongbin Sun;
Yanning Qian

Publication type:

Article

Cover Picture.

Published in:: 2016
Publication type:: Other

Erratum for "Wortmannin as targeted therapeutic agent for the treatment of triple-negative breast cancer".

Published in:: 2017
Publication type:: Correction Notice

Wortmannin as Targeted Therapeutic Agent for the Treatment of Triple-Negative Breast Cancer.

Published in:

Tropical Journal of Pharmaceutical Research, 2016, v. 15, n. 1, p. 95, doi. 10.4314/tjpr.v15i1.13

By:

Jian Li;
Fei Liu;
Yang Liu;
Jia-Jun Du;
Qi Liu

Publication type:

Article

Late Exercise Preconditioning Promotes Autophagy against Exhaustive Exercise-Induced Myocardial Injury through the Activation of the AMPK-mTOR-ULK1 Pathway.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/5697380

By:

Liu, Hong-Tao;
Pan, Shan-Shan

Publication type:

Article

Anti-hyperglycemic activity of Caralluma umbellata Haw.

Published in:

BioImpacts, 2014, v. 4, n. 3, p. 113, doi. 10.15171/bi.2014.003

By:

Bellamakondi, Pavan Kumar;
Godavarthi, Ashok;
Ibrahim, Mohammed

Publication type:

Article

Erythropoietin ameliorates PA-induced insulin resistance through the IRS/AKT/FOXO1 and GSK-3_ signaling pathway, and inhibits the inflammatory response in HepG2 cells.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 2, p. 2295, doi. 10.3892/mmr.2017.6810

By:

HONG ZHANG;
ZHIJUAN GE;
SUNYINYAN TANG;
RAN MENG;
YAN BI;
DALONG ZHU

Publication type:

Article

Inhibition of Rho-kinase by fasudil restores the cardioprotection of ischemic postconditioninng in hypercholesterolemic rat heart.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 5, p. 2517, doi. 10.3892/mmr.2014.2566

By:

NAN WU;
WENNA LI;
WENQI SHU;
YAN LV;
DALIN JIA

Publication type:

Article

Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways.

Published in:

Molecular Medicine Reports, 2014, v. 9, n. 4, p. 1371, doi. 10.3892/mmr.2014.1932

By:

GONGLI YANG;
FENG MA;
MUXIAO ZHONG;
LIN FANG;
YAO PENG;
XIAOMING XIN;
JIETAO ZHONG;
WEI ZHU;
YALI ZHANG

Publication type:

Article

Human and rodent pancreatic β-cells express IL-4 receptors and IL-4 protects against β-cell apoptosis by activation of the PI3K and JAK/STAT pathways.

Published in:

Bioscience Reports, 2010, v. 30, n. 3, p. 169, doi. 10.1042/BSR20090021

By:

KAMINSKI, Anna;
WELTERS, Hannah J.;
KAMINSKI, Edward R.;
MORGAN, Noel G.

Publication type:

Article

Uptake of fluorescent nano beads into BY2-cells involves clathrin-dependent and clathrin-independent endocytosis

Published in:

FEBS Letters, 2012, v. 586, n. 20, p. 3626, doi. 10.1016/j.febslet.2012.08.008

By:

Bandmann, Vera;
Müller, Jasmin Daniela;
Köhler, Tim;
Homann, Ulrike

Publication type:

Article

LY294002 inhibits TLR3/4-mediated IFN-β production via inhibition of IRF3 activation with a PI3K-independent mechanism

Published in:

FEBS Letters, 2012, v. 586, n. 6, p. 705, doi. 10.1016/j.febslet.2012.01.016

By:

Zhao, Wei;
Qi, Jianni;
Wang, Lijuan;
Zhang, Meng;
Wang, Peng;
Gao, Chengjiang

Publication type:

Article

Ameliorative effect of sevoflurane on endoplasmic reticulum stress mediates cardioprotection against ischemia–reperfusion injury1.

Published in:

Canadian Journal of Physiology & Pharmacology, 2019, v. 97, n. 5, p. 345, doi. 10.1139/cjpp-2018-0016

By:

Liu, Ai-Jie;
Pang, Chun-Xia;
Liu, Guo-Qiang;
Wang, Shi-Duan;
Chu, Chun-Qin;
Li, Lin-Zhang;
Dong, Yan;
Zhu, De-Zhang

Publication type:

Article

PI3Kγ contributes to MEK1/2 activation in oxidative glutamate toxicity via PDK1.

Published in:

Journal of Neurochemistry, 2013, v. 127, n. 1, p. 139, doi. 10.1111/jnc.12364

By:

Ha, Jong Seong;
Kwon, Ki‐Sun;
Park, Sung Sup

Publication type:

Article

Effect of pioglitazone on the abrogated cardioprotective effect of ischemic preconditioning in hyperlipidemic rat heart.

Published in:

Indian Journal of Pharmacology, 2016, v. 48, n. 1, p. 59, doi. 10.4103/0253-7613.174545

By:

Mittal, Dhiraj;
Taliyan, Rajeev;
Sharma, P. L.;
Yadav, Harlokesh Narayan

Publication type:

Article

Influences of S100A8 and S100A9 on Proliferation of Nasopharyngeal Carcinoma Cells through PI3K/Akt Signaling Pathway.

Published in:

BioMed Research International, 2021, p. 1, doi. 10.1155/2021/9917365

By:

Wen, Liting;
Ding, Yu;
Chen, Xiaodong;
Tian, Keyong;
Li, Danfeng;
Liang, Kun;
Yue, Bo

Publication type:

Article