Works matching DE "WNT signal transduction"

Results: 3894

From preneoplastic lesion to heterogenous tumor: recent insights into hepatoblastoma biology and therapeutic opportunities.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02405-8

By:

Yang, Jun;
Davidoff, Andrew M.;
Murphy, Andrew J.

Publication type:

Article

Abnormal development of gastrointestinal system of homozygous Foxp2(R552H)-mutated mice.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08468-z

By:

Fujita-Jimbo, Eriko;
Nakamura, Sachie;
Sudo, Katsuko;
Momoi, Takashi

Publication type:

Article

Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.

Published in:

Cancer Medicine, 2025, v. 14, n. 13, p. 1, doi. 10.1002/cam4.70993

By:

Liu, Jun;
Chen, Jiayu;
Jiang, Lianglei

Publication type:

Article

Wnt Signaling and Circular RNAs in Esophageal and Gastric Cancers: Opportunities for Early Detection and Targeted Therapy.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4805, doi. 10.3390/jcm14134805

By:

Chmielewski, Piotr Paweł;
Strzelec, Bartłomiej;
Rudno-Rudzińska, Julia

Publication type:

Article

Expression of WNT Family Genes in Mesenchymal Stromal Cells of the Hematopoietic Niche in Patients with Different Responses to Multiple Myeloma Treatment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6236, doi. 10.3390/ijms26136236

By:

Belik, Liubov A.;
Enukashvily, Natella I.;
Semenova, Natalia Y.;
Ostromyshenskii, Dmitrii I.;
Motyko, Ekaterina V.;
Kirienko, Anna N.;
Kustova, Daria V.;
Bessmeltsev, Stanislav S.;
Sidorkevich, Sergey V.;
Martynkevich, Irina S.

Publication type:

Article

Ursolic Acid Suppresses Colorectal Cancer Through Autophagy–Lysosomal Degradation of β-Catenin.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6210, doi. 10.3390/ijms26136210

By:

Lin, Chung-Ming;
Chao, Min-Chih;
Chen, Hsin-Han;
Chen, Hui-Jye

Publication type:

Article

Stem-Cell Niches in Health and Disease: Microenvironmental Determinants of Regeneration and Pathology.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 981, doi. 10.3390/cells14130981

By:

Yushkov, Boris;
Chereshnev, Valerii;
Korneva, Elena;
Yushkova, Victoria;
Sarapultsev, Alexey

Publication type:

Article

Epigenetic Modifiers to Treat Retinal Degenerative Diseases.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 961, doi. 10.3390/cells14130961

By:

Popova, Evgenya Y.;
Schneper, Lisa;
Sebastian, Aswathy;
Albert, Istvan;
Tombran-Tink, Joyce;
Barnstable, Colin J.

Publication type:

Article

Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization.

Published in:

Mediators of Inflammation, 2025, v. 2025, p. 1, doi. 10.1155/mi/7977933

By:

Lin, Jiahui;
Ke, Lingling;
Cheng, Sha;
Lu, Wei;
Hu, Yanan;
He, Xiyi;
Luo, Tingting;
Liu, Yuting;
Xu, Canxia;
Qi, Jian;
Medina-Contreras, Oscar

Publication type:

Article

Berberine hinders the malignant progression of non-small cell lung cancer via regulating E2F1/FZD8 signaling pathway.

Published in:

Applied Biological Chemistry, 2025, v. 68, n. 1, p. 1, doi. 10.1186/s13765-025-01013-w

By:

Liu, Shenping;
Tang, Chunmei

Publication type:

Article

Clinical and Functional Characterization of CD-NTase Enzymes in Esophageal Squamous Cell Carcinoma.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2822, doi. 10.7150/jca.100226

By:

Zhiwen Gong;
Hongcheng Zhong;
Shijiancong Liu;
Xujie Xiao;
Yuanquan Wu;
Xiaojian Li;
Qingdong Cao

Publication type:

Article

Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61551-1

By:

Martinez-Marin, Dalia;
Sharma, Monica;
van Wunnik, Jenna C.;
Sardela de Miranda, Flávia;
Boligala, Geetha Priya;
Jull, Ella C.;
Stroman, Grace C.;
Babcock, Rachel L.;
Pruitt, Kevin

Publication type:

Article

Distinct structural mechanisms of LGR4 modulation by Norrin and RSPOs in Wnt/β-catenin signaling.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61545-z

By:

Qiao, Huarui;
Hu, Fangzheng;
Wang, Yiang;
Wang, Lu;
Zhou, Siyu;
Guo, Shaojue;
Xu, Yiwen;
Xu, Jianfeng;
Cui, Qianqian;
Yang, Qilun;
Xu, H. Eric;
Zhu, Jianwei;
Geng, Yong

Publication type:

Article

Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104508

By:

Uveira, Julie;
Donati, Antoine;
Léria, Marvin;
Lechable, Marion;
Lahaye, François;
Vesque, Christine;
Houliston, Evelyn;
Tsuyoshi Momose

Publication type:

Article

Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100604

By:

Hanna, Joseph;
Touahri, Yacine;
Pak, Alissa;
Belfiore, Lauren;
van Oosten, Edwin;
David, Luke Ajay;
Han, Sisu;
Ilnytskyy, Yaroslav;
Kovalchuk, Igor;
Kurrasch, Deborah;
Satoshi Okawa;
del Sol, Antonio;
Screaton, Robert A.;
Aubert, Isabelle;
Schuurmans, Carol

Publication type:

Article

BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100497

By:

Guozhu Ning;
Yu Lin;
Haixia Ma;
Jiaqi Zhang;
Liping Yang;
Zhengyu Liu;
Lei Li;
Xinyu He;
Qiang Wang

Publication type:

Article

Endometrial stromal Menin supports endometrial receptivity by maintaining homeostasis of WNT signaling pathway through H3K4me3 during WOI.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08434-9

By:

Xu, Xin;
Han, Yichen;
Jin, Keer;
Xu, Weina;
Zhang, Huanyu;
Ma, Yana;
Li, Xiangjuan;
Wang, Haibin;
Liu, Mengying;
Lin, Xiaona

Publication type:

Article

Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1545952

By:

Zhang, Lingqiu;
Zhang, Fan;
Liang, Haimei;
Qin, Xiangling;
Mo, Yuemi;
Chen, Shiyi;
Xie, Jinling;
Hou, Xiaotao;
Deng, Jiagang;
Hao, Erwei;
Du, Zhengcai

Publication type:

Article

β-catenin safeguards cell survival via a transcription-independent mechanism during the induction of primitive streak from hESCs.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02559-w

By:

Zhang, Peng;
Li, Xu-Xia;
Bai, Hua-Jun;
Zhao, Yongxu;
Rao, Senle;
Liang, He;
Luo, Xiao-Ling;
Yang, Huang-Tian

Publication type:

Article

STK3 is a transcriptional target of YAP1 and a hub component in the crosstalk between Hippo and Wnt signaling pathways during gastric carcinogenesis.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02391-x

By:

Xie, Fuda;
Lyu, Yang;
Chen, Bonan;
Leung, Hoi Wing;
Yu, Peiyao;
Feng, Tiejun;
Fang, Canbin;
Cheung, Alvin H.K.;
Zhou, Bin;
Jiang, Jianhui;
Zhang, Ge;
Xu, Dazhi;
Li, Liang;
Jiang, Chen;
Chen, Jianwu;
Zhou, Zhaocai;
An, Liwei;
Huang, Bing;
Zhuang, Kangmin;
Luo, Xiaobei

Publication type:

Article

Positional BMP signaling orchestrates villus length in the small intestine.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60643-2

By:

Wang, Xu;
Li, Siqi;
Liu, Yuan;
Kuang, Xiangyu;
Chen, Jianxin;
Yu, Pei;
Zhao, Lianzheng;
Zhang, Ze;
Huang, Meimei;
Liu, Liansheng;
Zhang, Mengxian;
Wang, Yalong;
Ji, Weizhi;
Li, Jinsong;
Zhang, Lei;
Chen, Ye-Guang

Publication type:

Article

Non-canonical nuclear function of glutaminase cooperates with Wnt signaling to drive EMT during neural crest development.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58573-0

By:

Nekooie Marnany, Nioosha;
Dady, Alwyn;
Duband-Goulet, Isabelle;
Relaix, Frédéric;
Motterlini, Roberto;
Foresti, Roberta;
Dufour, Sylvie;
Duband, Jean-Loup

Publication type:

Article

Interplay between tumor cells and immune cells of the colorectal cancer tumor microenvironment: Wnt/β-catenin pathway.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587950

By:

Janeeh, Aisha Saleh;
Bajbouj, Khuloud;
Rah, Bilal;
Abu-Gharbieh, Eman;
Hamad, Mawieh

Publication type:

Article

Disruption of small intestinal mucosal homeostasis in mice with amiodarone induced steatohepatitis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-04680-3

By:

Kawauchi, Shoji;
Horibe, Sayo;
Tanaka, Toru;
Sasaki, Naoto;
Kunimasa, Junichi;
Rikitake, Yoshiyuki

Publication type:

Article

Wnt/Ca<sup>2+</sup> signaling: Dichotomous roles in regulating tumor progress (Review).

Published in:

Oncology Letters, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/ol.2025.15145

By:

Jing, Licong;
Wang, Hui;
Xia, Sheng;
Shao, Qixiang

Publication type:

Article

Diagnostic value of the wnt target and cancer-associated blood biomarker hPG80: ONCOPRO case-control prospective study.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00793-z

By:

You, Benoit;
Couraud, Sebastien;
Ceruse, Philippe;
Badet, Lionel;
Paparel, Philippe;
Durand, Alice;
Guillet, Marielle;
Merle, Philippe;
Lescuyer, Gaelle;
Philip, Charles-André;
Ducray, Francois;
Pioche, Mathieu;
Karlin, Lionel;
Lifante, Jean-Christophe;
Glehen, Olivier;
Bolze, Pierre-Adrien;
Chauvenet, Marion;
Langlois-Jacques, Carole;
Subtil, Fabien;
Piecyk, Marie

Publication type:

Article

Surgical Management of Intrathoracic Triton Tumors: Insights into Emerging Molecular and Epigenetic Mechanisms with a Case Series of Three Patients.

Published in:

Journal of Molecular Pathology, 2025, v. 6, n. 2, p. 10, doi. 10.3390/jmp6020010

By:

Bonis, Alessandro;
Busetto, Alberto;
Pezzuto, Federica;
Pagliarini, Giulia;
Verzeletti, Vincenzo;
Pezzella, Mario;
Cannone, Giorgio;
Faccioli, Eleonora;
Mammana, Marco;
Comacchio, Giovanni Maria;
Rebusso, Alessandro;
Schiavon, Marco;
Giraudo, Chiara;
Calabrese, Fiorella;
Dell'Amore, Andrea;
Nicotra, Samuele;
Dei Tos, Angelo Paolo;
Rea, Federico

Publication type:

Article

Targeting Cancer with Paris' Arrow: An Updated Perspective on Targeting Wnt Receptor Frizzled 7.

Published in:

Sci (2413-4155), 2025, v. 7, n. 2, p. 61, doi. 10.3390/sci7020061

By:

Hodson, Kieran;
Arredondo, Hector M.;
Humphrey, William E.;
Flanagan, Dustin J.;
Vincan, Elizabeth;
Willert, Karl;
Pearson, Helen B.;
Phesse, Toby J.

Publication type:

Article

Arhgef7 as a key target for enriched environment rescuing spatial cognitive deficits and anxiety-like behaviors in a mouse model of Alzheimer's disease following early social isolation.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01797-5

By:

Wang, Yimiao;
Wang, Ze;
Li, Yue;
Cao, Min;
Zhang, Shuying;
Ding, Shixin;
Chen, Sijia;
Jin, Yuxi;
Zhang, Yanli;
Gao, Junying;
Xiao, Ming

Publication type:

Article

Downregulation of S6 Kinase and Hedgehog–Gli1 by Inhibition of Fatty Acid Synthase in AML with FLT3-ITD Mutation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5721, doi. 10.3390/ijms26125721

By:

Kebenko, Maxim;
Zhuang, Ruimeng;
Hoffer, Konstantin;
Worthmann, Anna;
Horn, Stefan;
Kriegs, Malte;
Vorwerk, Jan;
von Bubnoff, Nikolas;
Khandanpour, Cyrus;
Gebauer, Niklas;
Gorantla, Sivahari Prasad;
Fiedler, Walter;
Bokemeyer, Carsten;
Jücker, Manfred

Publication type:

Article

PKA-Mediated Phosphorylation of SFRP4 Promotes Wnt/β-Catenin Activation and Cancer Stemness in Gastric Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5572, doi. 10.3390/ijms26125572

By:

Jhe, Yoo-Lim;
Lee, Suji;
Jung, Youjin;
Cheong, Jae-Ho

Publication type:

Article

XMU-MP-1, Inhibitor of STE20-like MST1/2 Kinases of the Hippo Signaling Pathway, Suppresses the Cell Cycle, Activates Apoptosis and Autophagy, and Induces Death of Hematopoietic Tumor Cells.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 874, doi. 10.3390/ph18060874

By:

Stepchenko, Alexander G.;
Georgieva, Sofia G.;
Pankratova, Elizaveta V.

Publication type:

Article

Colorectal Cancer Biomarker Identification via Joint DNA-Methylation and Transcriptomics Analysis Workflow.

Published in:

Genes, 2025, v. 16, n. 6, p. 620, doi. 10.3390/genes16060620

By:

Oladapo, Olajumoke B.;
Moussa, Marmar R.

Publication type:

Article

The you Gene Encodes an EGF-CUB Protein Essential for Hedgehog Signaling in Zebrafish.

Published in:

PLoS Biology, 2005, v. 3, n. 1, p. 1, doi. 10.1371/journal.pbio.0030066

By:

Woods, Ian G;
Talbot, William S

Publication type:

Article

Subcellular Localization of Frizzled Receptors, Mediated by Their Cytoplasmic Tails, Regulates Signaling Pathway Specificity.

Published in:

PLoS Biology, 2004, v. 2, n. 7, p. 1, doi. 10.1371/journal.pbio.0020158

By:

Wu, Jun;
Klein, Thomas J;
Mlodzik, Marek

Publication type:

Article

Neural Induction in Xenopus: Requirement for Ectodermal and Endomesodermal Signals via Chordin, Noggin, β-Catenin, and Cerberus.

Published in:

PLoS Biology, 2004, v. 2, n. 5, p. 1, doi. 10.1371/journal.pbio.0020092

By:

Kuroda, Hiroki;
Wessely, Oliver;
Robertis, E. M. De

Publication type:

Article

Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor.

Published in:

PLoS Biology, 2004, v. 2, n. 3, p. 1, doi. 10.1371/journal.pbio.0020065

By:

Yao, Guang;
Craven, Mark;
Drinkwater, Norman;
Bradfield, Christopher A

Publication type:

Article

A Nuclear Function for Armadillo/β-Catenin.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020095

By:

Tolwinski, Nicholas S;
Wieschaus, Eric

Publication type:

Article

A Wingless Flight.

Published in:

PLoS Biology, 2003, v. 1, n. 12, p. 1, doi. 10.1371/journal.pbio.0000049

By:

Yu, Xiang

Publication type:

Article

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway.

Published in:

PLoS Biology, 2003, v. 1, n. 10, p. 1, doi. 10.1371/journal.pbio.0000010

By:

Lee, Ethan;
Salic, Adrian;
Krüger, Roland;
Heinrich, Reinhart;
Kirschner, Marc W

Publication type:

Article

Nanodiamonds Interfere with Wnt-Regulated Cell Migration and Adipocyte Differentiation in Cells and Embryonic Development In Vivo.

Published in:

Particle & Particle Systems Characterization, 2017, v. 34, n. 1, p. n/a, doi. 10.1002/ppsc.201600208

By:

Yi, Hongyang;
Li, Xiaojiao;
Wang, Zhuyao;
Yin, Min;
Wang, Lihua;
Aldalbahi, Ali;
El‐Sayed, Nahed Nasser;
Wang, Hui;
Chen, Nan;
Chen, Luonan;
Fan, Chunhai;
Song, Haiyun

Publication type:

Article

Epigenetically controlled Six3 expression regulates glioblastoma cell proliferation and invasion alongside modulating the activation levels of WNT pathway members.

Published in:

Journal of Neuro-Oncology, 2017, v. 133, n. 3, p. 509, doi. 10.1007/s11060-017-2476-y

By:

Zhang, Baoxin;
Shen, Chenfu;
Ge, Fengyun;
Ma, Tingting;
Zhang, Zuping

Publication type:

Article

Stimulation of mouse vibrissal follicle growth by recombinant human fibroblast growth factor 20.

Published in:

Biotechnology Letters, 2018, v. 40, n. 6, p. 1009, doi. 10.1007/s10529-018-2554-z

By:

Xu, Xue-Gang;
Gong, Lin;
Jiang, Tian-Ling;
Li, Yuan-Hong;
Gao, Xing-Hua;
Tian, Haishan;
Chen, Hong-Duo

Publication type:

Article

FZD7 accelerates hepatic metastases in pancreatic cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00509-1

By:

Zhang, Zhongbo;
Xu, Yuanhong

Publication type:

Article

Roles of ARID1A variations in colorectal cancer: a collaborative review.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00469-6

By:

Zhao, Shankun;
Wu, Weizhou;
Jiang, Zufu;
Tang, Fuqin;
Ding, Lingzhi;
Xu, Weifang;
Ruan, Libin

Publication type:

Article

Microfibrillar-associated protein 5 regulates osteogenic differentiation by modulating the Wnt/β-catenin and AMPK signaling pathways.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00413-0

By:

Li, Haoran;
Zhou, Wuling;
Sun, Shiwei;
Zhang, Tianlong;
Zhang, Tieqi;
Huang, Haitian;
Wang, Minghai

Publication type:

Article

Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/β-catenin signaling in immune cells from PTSD patients leading to inflammatory phenotype.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00238-3

By:

Bam, Marpe;
Yang, Xiaoming;
Busbee, Brandon P.;
Aiello, Allison E.;
Uddin, Monica;
Ginsberg, Jay P.;
Galea, Sandro;
Nagarkatti, Prakash S.;
Nagarkatti, Mitzi

Publication type:

Article

Investigation of the Effects of Silymarin on Ovarian Ischemia Reperfusion via Nrf‐2/HO‐1/NQO1, Ki‐67 and Wnt Signaling Pathways.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70138

By:

Öztürk, Ayşe Betül;
Akaras, Nurhan;
Şimşek, Hasan;
Kandemir, Fatih Mehmet

Publication type:

Article

FZD3 regulates the viability, apoptosis, and extracellular matrix degradation of vaginal wall fibroblasts in pelvic organ prolapse via the Wnt signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 2, p. 1, doi. 10.1002/jbt.23654

By:

Li, Jie;
Zhang, Junqin;
Chu, Zhaoping;
Han, Hua;
Zhang, Yuan

Publication type:

Article

CGRP induces myofibroblast differentiation and the production of extracellular matrix in MRC5s via autocrine and paracrine signalings.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 12, p. 1, doi. 10.1002/jbt.23204

By:

Kayalar, Ozgecan;
Oztay, Fusun

Publication type:

Article